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The map label for this gene is trpG

Identifier: 15668413

GI number: 15668413

Start: 229852

End: 230445

Strand: Direct

Name: trpG

Synonym: MJ0238

Alternate gene names: 15668413

Gene position: 229852-230445 (Clockwise)

Preceding gene: 15668412

Following gene: 15668414

Centisome position: 13.81

GC content: 32.66

Gene sequence:

>594_bases
ATGGAGGTTAAAAAAGTGCTTGTTATCGACAATATTGACTCATTTGTCTGGAATTTAGTCCAATATGTAGGGACTTTAGG
GTATAAAGTTAAGTTAGTGGATAACAAAATCACATTAGATGAAATAAAGAAAATAAATCCAGATAGAATAATTATAAGCC
CAGGACCAAAAACTCCAAAAGAGGCTGGAAATTGTATAAAGATTATTCAAGAGGTAGATATTCCAATATTGGGAGTTTGT
TTAGGACATCAGTGTATTGTTGAGGCGTTTGGTGGAGAGGTTGGGAGAGCAAAGAGAGTTATGCATGGAAAGGCAAGTTT
AATAAATCATGATGGAGAAGGTATCTTTAAAGACATTCCCAATCCATTCTATGGAGGAAGGTATCATTCTTTAATAGCTA
AAGAAGTTCCAAAAGAGTTAAAAATAACTGCTAAGAGTTTAGATGATAACTATATTATGGGAGTTAGGCATAAAAAGCTA
CCAATTGAAGGTGTTCAGTTCCATCCGGAGAGTATATTAACTGAATCAGATAACTTAAAATTCCCAGATTTGGGCTTAAA
ACTTATTAAAAATTTTGTTGAAAGTGAATATTAA

Upstream 100 bases:

>100_bases
AAATTTTTAAGATTTTTATAGTAAAAGGTGATTATTATCCTTTATAATTATGTCTTATATTTTAATGTTAGGATGGGACA
ATTTTGGGGGATTGATTTAA

Downstream 100 bases:

>100_bases
CTTCTTAAAATTAGTTAAAAATTTAAAAATTTCAAAAAGAAATCTTAAGTGAAAAATATGGATGTTTATGAAATACTATA
CCAATTTTGCTTAGAATATG

Product: anthranilate synthase component II TrpG

Products: NA

Alternate protein names: Glutamine amido-transferase

Number of amino acids: Translated: 197; Mature: 197

Protein sequence:

>197_residues
MEVKKVLVIDNIDSFVWNLVQYVGTLGYKVKLVDNKITLDEIKKINPDRIIISPGPKTPKEAGNCIKIIQEVDIPILGVC
LGHQCIVEAFGGEVGRAKRVMHGKASLINHDGEGIFKDIPNPFYGGRYHSLIAKEVPKELKITAKSLDDNYIMGVRHKKL
PIEGVQFHPESILTESDNLKFPDLGLKLIKNFVESEY

Sequences:

>Translated_197_residues
MEVKKVLVIDNIDSFVWNLVQYVGTLGYKVKLVDNKITLDEIKKINPDRIIISPGPKTPKEAGNCIKIIQEVDIPILGVC
LGHQCIVEAFGGEVGRAKRVMHGKASLINHDGEGIFKDIPNPFYGGRYHSLIAKEVPKELKITAKSLDDNYIMGVRHKKL
PIEGVQFHPESILTESDNLKFPDLGLKLIKNFVESEY
>Mature_197_residues
MEVKKVLVIDNIDSFVWNLVQYVGTLGYKVKLVDNKITLDEIKKINPDRIIISPGPKTPKEAGNCIKIIQEVDIPILGVC
LGHQCIVEAFGGEVGRAKRVMHGKASLINHDGEGIFKDIPNPFYGGRYHSLIAKEVPKELKITAKSLDDNYIMGVRHKKL
PIEGVQFHPESILTESDNLKFPDLGLKLIKNFVESEY

Specific function: Catalyzes The Biosynthesis Of 4-Amino-4-Deoxychorismate (Adc) From Chorismate And Glutamine. [C]

COG id: COG0512

COG function: function code EH; Anthranilate/para-aminobenzoate synthases component II

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 glutamine amidotransferase type-1 domain

Homologues:

Organism=Escherichia coli, GI1789760, Length=194, Percent_Identity=47.9381443298969, Blast_Score=178, Evalue=3e-46,
Organism=Escherichia coli, GI1787517, Length=178, Percent_Identity=41.0112359550562, Blast_Score=146, Evalue=7e-37,
Organism=Escherichia coli, GI1786215, Length=180, Percent_Identity=28.8888888888889, Blast_Score=77, Evalue=8e-16,
Organism=Saccharomyces cerevisiae, GI6322638, Length=183, Percent_Identity=49.1803278688525, Blast_Score=170, Evalue=1e-43,
Organism=Saccharomyces cerevisiae, GI6324361, Length=220, Percent_Identity=30, Blast_Score=73, Evalue=3e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): TRPG_METJA (Q57690)

Other databases:

- EMBL:   L77117
- PIR:   G64329
- RefSeq:   NP_247209.1
- ProteinModelPortal:   Q57690
- SMR:   Q57690
- GeneID:   1451092
- GenomeReviews:   L77117_GR
- KEGG:   mja:MJ_0238
- NMPDR:   fig|243232.1.peg.246
- TIGR:   MJ0238
- HOGENOM:   HBG292341
- OMA:   NSENIIM
- ProtClustDB:   CLSK2517561
- BioCyc:   MJAN243232:MJ_0238-MONOMER
- BRENDA:   4.1.3.27
- InterPro:   IPR006220
- InterPro:   IPR011702
- InterPro:   IPR017926
- InterPro:   IPR000991
- InterPro:   IPR006221
- PRINTS:   PR00097
- PRINTS:   PR00096
- TIGRFAMs:   TIGR00566

Pfam domain/function: PF00117 GATase

EC number: =4.1.3.27

Molecular weight: Translated: 22061; Mature: 22061

Theoretical pI: Translated: 8.08; Mature: 8.08

Prosite motif: PS51273 GATASE_TYPE_1; PS00442 GATASE_TYPE_I

Important sites: ACT_SITE 80-80 ACT_SITE 168-168 ACT_SITE 170-170

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEVKKVLVIDNIDSFVWNLVQYVGTLGYKVKLVDNKITLDEIKKINPDRIIISPGPKTPK
CCCEEEEEEECHHHHHHHHHHHHHCCCEEEEEECCEECHHHHHCCCCCEEEECCCCCCHH
EAGNCIKIIQEVDIPILGVCLGHQCIVEAFGGEVGRAKRVMHGKASLINHDGEGIFKDIP
HHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHCHHHHCCCCCCCHHHHCC
NPFYGGRYHSLIAKEVPKELKITAKSLDDNYIMGVRHKKLPIEGVQFHPESILTESDNLK
CCCCCCHHHHHHHHHCCHHHEEHHHCCCCCEEEEEECCCCCCCCCEECCHHHCCCCCCCC
FPDLGLKLIKNFVESEY
CCHHHHHHHHHHHHCCC
>Mature Secondary Structure
MEVKKVLVIDNIDSFVWNLVQYVGTLGYKVKLVDNKITLDEIKKINPDRIIISPGPKTPK
CCCEEEEEEECHHHHHHHHHHHHHCCCEEEEEECCEECHHHHHCCCCCEEEECCCCCCHH
EAGNCIKIIQEVDIPILGVCLGHQCIVEAFGGEVGRAKRVMHGKASLINHDGEGIFKDIP
HHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHCHHHHCCCCCCCHHHHCC
NPFYGGRYHSLIAKEVPKELKITAKSLDDNYIMGVRHKKLPIEGVQFHPESILTESDNLK
CCCCCCHHHHHHHHHCCHHHEEHHHCCCCCEEEEEECCCCCCCCCEECCHHHCCCCCCCC
FPDLGLKLIKNFVESEY
CCHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087