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The map label for this gene is argS

Identifier: 15668412

GI number: 15668412

Start: 228020

End: 229720

Strand: Direct

Name: argS

Synonym: MJ0237

Alternate gene names: 15668412

Gene position: 228020-229720 (Clockwise)

Preceding gene: 15668411

Following gene: 15668413

Centisome position: 13.7

GC content: 31.22

Gene sequence:

>1701_bases
ATGGATATCAAAAGTAATATCATCAATGCATTAAAAGAAGTAATTAGCAAAGAGATATGTAAAGAGATTGACATAAAGTT
GGATAAAACACCAAACTTAGAGTTAGGAGATTATTCTGTAAATATCTGCTTCAGATTAGCTAAAGAGCTAAAAAAGAATC
CAAAAATTATTGCTGAAGAGTTGGTAGATAAGTTAAAAGCTATGAACATTGAAGGAGTTAAAGAGATAAAGGCAGTCAAT
GGATATATAAACTTCTATATTGATTATAACAAATTTGCTAAAAATTTAATGGAAGAGATTGATAAAAAAGGAAATAATTA
TGGTAGAGGAGATAAAAAATCTATAAAAATCATCTTAGAACATACATCAGCAAATCCAAATGGGCCTTTACATATTGGAC
ATTTAAGAAATGCCATTATTGGAGATTGTTTAAAGAGAATATTAGAATTCTATGGATATGATGTTGAAACCCACTACTAT
GTAAATGATATGGGTAGGCAGATGGCTTTGGTTGTTTATGGAATTGAATTATTTGGTTTAGACAAAGAAAAAAAGAAAGA
CCATGCAATTGCTGAAACTTATGTAAAAATTAATAAATATTTGGAAGAGCATCCAGAAGAGGAAGAAAAGATTCTTGAAT
TAATGAGAAAGTATGAAGATGCTTTAGAAAACAATGAAGATAATGAAATAACTAAAAAATTTGAATTTGCAGTAAATTAT
GCATTGGATGGAATAAAAGAGACATTAAAGAATTTAAATATTAAGCATGATACCTTTGTTTGGGAAAGCTCTTATGTAAG
AAATGGAATGGTTAAAAAGGTTATAGAAAAATTAATGGAAACTGGAAAGGTAATTAAAGAAGAAACCTATATGCTTGATT
TATCAGACTTTGGCATTGAAAAGAAAATGGTTTTAGCAAGGGCAAACGGAACAAGCTTGTATTCAACAAGAGATATTGCC
TATCACTTAGATAAGTTATCAAAGTGCGATATAGGAATAGATGTCTTAGGGGCTGACCACAAATTAACGGCAGAGATGGT
TAAAGCAGCTTTAAAACTCCTTGGAAGCAAAGTGCCAGAAGTTATATTCTATGAATTCATCTCCCTTCCAGAAGGTTCAA
TGAGTACAAGAAGAGGAAGATTTATAAGTACCGATGAGTTGTTAGAAGAGGCGATAAAAAGGGCTAAAGAAGAGTGTAAT
AAGAGAGGTGTTGAGGAAAATATTGCCTATGATATTGGATTAGGGGCAGTTAGATACAACATTGCAAGAATTTCTCCTGA
AAAGCCAATGGTATTTAGATGGGAAGAAGCCTTAGACTTTGAAAAAGTTGGATGTCCATTTATACAGTATGCACACGCAA
GATGTTGCAGTATTTTAAAAGAAGCGGAAAATAAAGGAGTTAAAGATGAAGCAGTATTTAACTATGAACTAACCAGTGAG
GAGAAAGAATTAATTAAGATGTTGGATGAATTTAAGGATATAATTAAAGAGAGTGCTGAAAGTAGAAGAGTACATATATT
AGCCAACTACTTATTAGAGCTTGCCAAGGCATTCAATAGATTTTACGCAAACTGTCCAATTTTAATGACAAAAGTTGATG
ATGATGTTAAAAAATCAAGATTAAAGTTGGTTAAAAGCACTAAGACAGTATTAGAGACAGGTTTAGAATTGTTAGGAATA
AATTGCCCAGGAAGGATGTAG

Upstream 100 bases:

>100_bases
AAACTTTTCTATCATTTATTTAAATTAATAAATTAAAAAGAAGGTATTTAAAGAAAATCCCCAATTTTTAAATTAAATAA
AAAATGAGAGAGGGAAGACT

Downstream 100 bases:

>100_bases
GATGTAAAATTATTTAATTATTTTTTGTACTAAATTTTTAAGATTTTTATAGTAAAAGGTGATTATTATCCTTTATAATT
ATGTCTTATATTTTAATGTT

Product: arginyl-tRNA synthetase

Products: NA

Alternate protein names: Arginine--tRNA ligase; ArgRS

Number of amino acids: Translated: 566; Mature: 566

Protein sequence:

>566_residues
MDIKSNIINALKEVISKEICKEIDIKLDKTPNLELGDYSVNICFRLAKELKKNPKIIAEELVDKLKAMNIEGVKEIKAVN
GYINFYIDYNKFAKNLMEEIDKKGNNYGRGDKKSIKIILEHTSANPNGPLHIGHLRNAIIGDCLKRILEFYGYDVETHYY
VNDMGRQMALVVYGIELFGLDKEKKKDHAIAETYVKINKYLEEHPEEEEKILELMRKYEDALENNEDNEITKKFEFAVNY
ALDGIKETLKNLNIKHDTFVWESSYVRNGMVKKVIEKLMETGKVIKEETYMLDLSDFGIEKKMVLARANGTSLYSTRDIA
YHLDKLSKCDIGIDVLGADHKLTAEMVKAALKLLGSKVPEVIFYEFISLPEGSMSTRRGRFISTDELLEEAIKRAKEECN
KRGVEENIAYDIGLGAVRYNIARISPEKPMVFRWEEALDFEKVGCPFIQYAHARCCSILKEAENKGVKDEAVFNYELTSE
EKELIKMLDEFKDIIKESAESRRVHILANYLLELAKAFNRFYANCPILMTKVDDDVKKSRLKLVKSTKTVLETGLELLGI
NCPGRM

Sequences:

>Translated_566_residues
MDIKSNIINALKEVISKEICKEIDIKLDKTPNLELGDYSVNICFRLAKELKKNPKIIAEELVDKLKAMNIEGVKEIKAVN
GYINFYIDYNKFAKNLMEEIDKKGNNYGRGDKKSIKIILEHTSANPNGPLHIGHLRNAIIGDCLKRILEFYGYDVETHYY
VNDMGRQMALVVYGIELFGLDKEKKKDHAIAETYVKINKYLEEHPEEEEKILELMRKYEDALENNEDNEITKKFEFAVNY
ALDGIKETLKNLNIKHDTFVWESSYVRNGMVKKVIEKLMETGKVIKEETYMLDLSDFGIEKKMVLARANGTSLYSTRDIA
YHLDKLSKCDIGIDVLGADHKLTAEMVKAALKLLGSKVPEVIFYEFISLPEGSMSTRRGRFISTDELLEEAIKRAKEECN
KRGVEENIAYDIGLGAVRYNIARISPEKPMVFRWEEALDFEKVGCPFIQYAHARCCSILKEAENKGVKDEAVFNYELTSE
EKELIKMLDEFKDIIKESAESRRVHILANYLLELAKAFNRFYANCPILMTKVDDDVKKSRLKLVKSTKTVLETGLELLGI
NCPGRM
>Mature_566_residues
MDIKSNIINALKEVISKEICKEIDIKLDKTPNLELGDYSVNICFRLAKELKKNPKIIAEELVDKLKAMNIEGVKEIKAVN
GYINFYIDYNKFAKNLMEEIDKKGNNYGRGDKKSIKIILEHTSANPNGPLHIGHLRNAIIGDCLKRILEFYGYDVETHYY
VNDMGRQMALVVYGIELFGLDKEKKKDHAIAETYVKINKYLEEHPEEEEKILELMRKYEDALENNEDNEITKKFEFAVNY
ALDGIKETLKNLNIKHDTFVWESSYVRNGMVKKVIEKLMETGKVIKEETYMLDLSDFGIEKKMVLARANGTSLYSTRDIA
YHLDKLSKCDIGIDVLGADHKLTAEMVKAALKLLGSKVPEVIFYEFISLPEGSMSTRRGRFISTDELLEEAIKRAKEECN
KRGVEENIAYDIGLGAVRYNIARISPEKPMVFRWEEALDFEKVGCPFIQYAHARCCSILKEAENKGVKDEAVFNYELTSE
EKELIKMLDEFKDIIKESAESRRVHILANYLLELAKAFNRFYANCPILMTKVDDDVKKSRLKLVKSTKTVLETGLELLGI
NCPGRM

Specific function: Unknown

COG id: COG0018

COG function: function code J; Arginyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family

Homologues:

Organism=Homo sapiens, GI197100773, Length=560, Percent_Identity=25.5357142857143, Blast_Score=135, Evalue=8e-32,
Organism=Homo sapiens, GI15149476, Length=610, Percent_Identity=22.9508196721311, Blast_Score=107, Evalue=4e-23,
Organism=Escherichia coli, GI1788184, Length=587, Percent_Identity=25.5536626916525, Blast_Score=176, Evalue=3e-45,
Organism=Caenorhabditis elegans, GI71985061, Length=621, Percent_Identity=23.8325281803543, Blast_Score=130, Evalue=2e-30,
Organism=Caenorhabditis elegans, GI71985068, Length=584, Percent_Identity=23.6301369863014, Blast_Score=121, Evalue=9e-28,
Organism=Caenorhabditis elegans, GI17532153, Length=497, Percent_Identity=24.9496981891348, Blast_Score=99, Evalue=7e-21,
Organism=Saccharomyces cerevisiae, GI6320548, Length=594, Percent_Identity=27.6094276094276, Blast_Score=182, Evalue=2e-46,
Organism=Saccharomyces cerevisiae, GI6321883, Length=566, Percent_Identity=23.8515901060071, Blast_Score=139, Evalue=8e-34,
Organism=Drosophila melanogaster, GI28571570, Length=620, Percent_Identity=26.6129032258064, Blast_Score=147, Evalue=3e-35,
Organism=Drosophila melanogaster, GI18859963, Length=595, Percent_Identity=24.3697478991597, Blast_Score=107, Evalue=2e-23,

Paralogues:

None

Copy number: 789 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 800 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): SYR_METJA (Q57689)

Other databases:

- EMBL:   L77117
- PIR:   F64329
- RefSeq:   NP_247208.1
- ProteinModelPortal:   Q57689
- SMR:   Q57689
- GeneID:   1451091
- GenomeReviews:   L77117_GR
- KEGG:   mja:MJ_0237
- NMPDR:   fig|243232.1.peg.245
- TIGR:   MJ0237
- HOGENOM:   HBG695395
- OMA:   NDMGRQI
- ProtClustDB:   PRK01611
- BioCyc:   MJAN243232:MJ_0237-MONOMER
- BRENDA:   6.1.1.19
- GO:   GO:0005737
- HAMAP:   MF_00123
- InterPro:   IPR001412
- InterPro:   IPR001278
- InterPro:   IPR015945
- InterPro:   IPR005148
- InterPro:   IPR008909
- InterPro:   IPR014729
- InterPro:   IPR009080
- Gene3D:   G3DSA:3.30.1360.70
- Gene3D:   G3DSA:3.40.50.620
- PANTHER:   PTHR11956
- PRINTS:   PR01038
- SMART:   SM00836
- TIGRFAMs:   TIGR00456

Pfam domain/function: PF03485 Arg_tRNA_synt_N; PF05746 DALR_1; PF00750 tRNA-synt_1d; SSF55190 Arg-tRNA-synth_Ic_N; SSF47323 tRNAsyn_1a_bind

EC number: =6.1.1.19

Molecular weight: Translated: 64980; Mature: 64980

Theoretical pI: Translated: 6.33; Mature: 6.33

Prosite motif: PS00178 AA_TRNA_LIGASE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDIKSNIINALKEVISKEICKEIDIKLDKTPNLELGDYSVNICFRLAKELKKNPKIIAEE
CCCHHHHHHHHHHHHHHHHHHHHCCEECCCCCCEECCCHHHHHHHHHHHHHCCCHHHHHH
LVDKLKAMNIEGVKEIKAVNGYINFYIDYNKFAKNLMEEIDKKGNNYGRGDKKSIKIILE
HHHHHHHCCCCHHHHHHHHCCEEEEEEEHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEEE
HTSANPNGPLHIGHLRNAIIGDCLKRILEFYGYDVETHYYVNDMGRQMALVVYGIELFGL
ECCCCCCCCEEHHHHHHHHHHHHHHHHHHHHCCCCEEEEEHHHHCHHHHHHEEEHHHCCC
DKEKKKDHAIAETYVKINKYLEEHPEEEEKILELMRKYEDALENNEDNEITKKFEFAVNY
CCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHH
ALDGIKETLKNLNIKHDTFVWESSYVRNGMVKKVIEKLMETGKVIKEETYMLDLSDFGIE
HHHHHHHHHHHCCCCCCEEEECHHHHHCHHHHHHHHHHHHHHHHHHHHHEEEEHHHCCCC
KKMVLARANGTSLYSTRDIAYHLDKLSKCDIGIDVLGADHKLTAEMVKAALKLLGSKVPE
CEEEEEECCCCCCCCHHHHHHHHHHHCCCCCCEEEECCCCHHHHHHHHHHHHHHHCCCHH
VIFYEFISLPEGSMSTRRGRFISTDELLEEAIKRAKEECNKRGVEENIAYDIGLGAVRYN
HHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHCHHCCCCHHHHHH
IARISPEKPMVFRWEEALDFEKVGCPFIQYAHARCCSILKEAENKGVKDEAVFNYELTSE
HEEECCCCCCEEEEHHHCCHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCH
EKELIKMLDEFKDIIKESAESRRVHILANYLLELAKAFNRFYANCPILMTKVDDDVKKSR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCHHHHHHH
LKLVKSTKTVLETGLELLGINCPGRM
HHHHHHHHHHHHCCHHHEECCCCCCC
>Mature Secondary Structure
MDIKSNIINALKEVISKEICKEIDIKLDKTPNLELGDYSVNICFRLAKELKKNPKIIAEE
CCCHHHHHHHHHHHHHHHHHHHHCCEECCCCCCEECCCHHHHHHHHHHHHHCCCHHHHHH
LVDKLKAMNIEGVKEIKAVNGYINFYIDYNKFAKNLMEEIDKKGNNYGRGDKKSIKIILE
HHHHHHHCCCCHHHHHHHHCCEEEEEEEHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEEE
HTSANPNGPLHIGHLRNAIIGDCLKRILEFYGYDVETHYYVNDMGRQMALVVYGIELFGL
ECCCCCCCCEEHHHHHHHHHHHHHHHHHHHHCCCCEEEEEHHHHCHHHHHHEEEHHHCCC
DKEKKKDHAIAETYVKINKYLEEHPEEEEKILELMRKYEDALENNEDNEITKKFEFAVNY
CCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHH
ALDGIKETLKNLNIKHDTFVWESSYVRNGMVKKVIEKLMETGKVIKEETYMLDLSDFGIE
HHHHHHHHHHHCCCCCCEEEECHHHHHCHHHHHHHHHHHHHHHHHHHHHEEEEHHHCCCC
KKMVLARANGTSLYSTRDIAYHLDKLSKCDIGIDVLGADHKLTAEMVKAALKLLGSKVPE
CEEEEEECCCCCCCCHHHHHHHHHHHCCCCCCEEEECCCCHHHHHHHHHHHHHHHCCCHH
VIFYEFISLPEGSMSTRRGRFISTDELLEEAIKRAKEECNKRGVEENIAYDIGLGAVRYN
HHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHCHHCCCCHHHHHH
IARISPEKPMVFRWEEALDFEKVGCPFIQYAHARCCSILKEAENKGVKDEAVFNYELTSE
HEEECCCCCCEEEEHHHCCHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCH
EKELIKMLDEFKDIIKESAESRRVHILANYLLELAKAFNRFYANCPILMTKVDDDVKKSR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCHHHHHHH
LKLVKSTKTVLETGLELLGINCPGRM
HHHHHHHHHHHHCCHHHEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087