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The map label for this gene is 15668211

Identifier: 15668211

GI number: 15668211

Start: 40474

End: 41838

Strand: Reverse

Name: 15668211

Synonym: MJ0041

Alternate gene names: NA

Gene position: 41838-40474 (Counterclockwise)

Preceding gene: 15668212

Following gene: 15668210

Centisome position: 2.51

GC content: 31.28

Gene sequence:

>1365_bases
ATGGCTAGTATAATAAATAAGCAAATAATAAGTCCAACGGGGAGAAACATGGAGATTATAAATTATGAAATATTAAAAAA
ATATCCTCTCTGTGATAGATGCTTTGGAAGGTTGTATGCTAAGTTATTACATACAACAAACACTGAAAGAGGTAGGGCGT
TAAAGCTATATAAAGCTTTGGAACTTGAGGCAAAGATAAAAAAAGCTAAGGAAAAAGGAATAAATTATGAAGAAGAATTA
GAGTTATTAAAAGCTTTGGCAAAAAGTGGAGTTGATGAAATAAGATTGGAAGATATAGAGATAGAGAAAGAGAACTGCCC
ATGGTGTAGAGGCATTTTTAACAAACAAAAAATGGAAAAGTTGTTAAATAAAGCCATTGAACTTTTAAAAGAATATGATT
TTGATACATTTTTAATTGGAACTCACATACCAGAAGAGATTAAAGACCTTGAGAAAGAGATTGAAACAGAATTTATGGAG
AGTATAAAGCAGGAATTTGGTAGAGAATTTGGGAAGATGTTGGCAGTTAGGTTAGATAAAGCCCCAGATAAAGAATATCC
AGATATTGTTGTGCATATAAATCCATACACTGAAGAAATCTATCTACAAATAAATCCTTTATTTATTAAAGGAAGATATA
GAAAATTAGTTAGGGGGATTCCACAAACAAGATGGCCTTGCAGAAAGTGTAGAGGAAAAGGTTGTGAGCTCTGCAACTAC
ACAGGTAAAAAATATCCAATATCAGTTGAAGAAATTATTGCCAAACCATTCTTAGAGGCAACAAAAGGAGTAGATGCAAA
ATTCCATGGAGCTGGGAGAGAAGATATTGATGTAAGAATGCTTGGAGATGGAAGACCATTTGTTTTAGAGATTAAAGAGC
CAAAGATAAGAAAAATTGATTTAAATAAAATTGCTGAGGAAATTAATAAGGATGGTAGAGTAGAGGTTTTAAACTTAGAG
TTTGGTGTTAGGAAGGATAAAGTTATATTTAAAAACACTCCACATAGAAAAACATATAGGGCTTTAGTTGAATGCTCTGA
TAAAATTACTGATGAAGAACTAAAACTCCTTGAAAAAGAACTTGAAAATAGAACTATCTATCAAAAAACACCAAAAAGGG
TTTTACATAGAAGAGCTGATTTAGAGAGAATCCGTAAGGTATATAAAGTTAAAACCAGTAAAGTAGATGACAATCATTTT
GAGATGATTATATATTGTGATGGTGGATTATATATAAAAGAGCTAATCAGTGGAGATGATGGGAGAACAAACCCATCAGT
CTCATCTATATTAAATAAAAACTGTATCTGTAAGGAATTAGATGTTTTGAAAATACACGATAACAACCTTTTAGAAAAAG
GTTGA

Upstream 100 bases:

>100_bases
AGTTAATTGAAAAGCTTATAAAGTGTTGGATTGCATTTTGGGAGCCAACAATGATTTAAAACTTACTTAATTTTTAATAT
TAACTATATTATGAACTATC

Downstream 100 bases:

>100_bases
TCAAAACAGATGCATTAAGTTGCCTCTTTCAGAGGCAATTAATGCCTCATTTAAAAACCTATTCAAAAAGGTGAGAATTA
TGGTTCAAATGAGTGAAGGA

Product: putative pseudouridylate synthase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 454; Mature: 453

Protein sequence:

>454_residues
MASIINKQIISPTGRNMEIINYEILKKYPLCDRCFGRLYAKLLHTTNTERGRALKLYKALELEAKIKKAKEKGINYEEEL
ELLKALAKSGVDEIRLEDIEIEKENCPWCRGIFNKQKMEKLLNKAIELLKEYDFDTFLIGTHIPEEIKDLEKEIETEFME
SIKQEFGREFGKMLAVRLDKAPDKEYPDIVVHINPYTEEIYLQINPLFIKGRYRKLVRGIPQTRWPCRKCRGKGCELCNY
TGKKYPISVEEIIAKPFLEATKGVDAKFHGAGREDIDVRMLGDGRPFVLEIKEPKIRKIDLNKIAEEINKDGRVEVLNLE
FGVRKDKVIFKNTPHRKTYRALVECSDKITDEELKLLEKELENRTIYQKTPKRVLHRRADLERIRKVYKVKTSKVDDNHF
EMIIYCDGGLYIKELISGDDGRTNPSVSSILNKNCICKELDVLKIHDNNLLEKG

Sequences:

>Translated_454_residues
MASIINKQIISPTGRNMEIINYEILKKYPLCDRCFGRLYAKLLHTTNTERGRALKLYKALELEAKIKKAKEKGINYEEEL
ELLKALAKSGVDEIRLEDIEIEKENCPWCRGIFNKQKMEKLLNKAIELLKEYDFDTFLIGTHIPEEIKDLEKEIETEFME
SIKQEFGREFGKMLAVRLDKAPDKEYPDIVVHINPYTEEIYLQINPLFIKGRYRKLVRGIPQTRWPCRKCRGKGCELCNY
TGKKYPISVEEIIAKPFLEATKGVDAKFHGAGREDIDVRMLGDGRPFVLEIKEPKIRKIDLNKIAEEINKDGRVEVLNLE
FGVRKDKVIFKNTPHRKTYRALVECSDKITDEELKLLEKELENRTIYQKTPKRVLHRRADLERIRKVYKVKTSKVDDNHF
EMIIYCDGGLYIKELISGDDGRTNPSVSSILNKNCICKELDVLKIHDNNLLEKG
>Mature_453_residues
ASIINKQIISPTGRNMEIINYEILKKYPLCDRCFGRLYAKLLHTTNTERGRALKLYKALELEAKIKKAKEKGINYEEELE
LLKALAKSGVDEIRLEDIEIEKENCPWCRGIFNKQKMEKLLNKAIELLKEYDFDTFLIGTHIPEEIKDLEKEIETEFMES
IKQEFGREFGKMLAVRLDKAPDKEYPDIVVHINPYTEEIYLQINPLFIKGRYRKLVRGIPQTRWPCRKCRGKGCELCNYT
GKKYPISVEEIIAKPFLEATKGVDAKFHGAGREDIDVRMLGDGRPFVLEIKEPKIRKIDLNKIAEEINKDGRVEVLNLEF
GVRKDKVIFKNTPHRKTYRALVECSDKITDEELKLLEKELENRTIYQKTPKRVLHRRADLERIRKVYKVKTSKVDDNHFE
MIIYCDGGLYIKELISGDDGRTNPSVSSILNKNCICKELDVLKIHDNNLLEKG

Specific function: Unknown

COG id: COG1258

COG function: function code J; Predicted pseudouridylate synthase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 THUMP domain

Homologues:

Organism=Homo sapiens, GI207113130, Length=250, Percent_Identity=34, Blast_Score=132, Evalue=5e-31,
Organism=Caenorhabditis elegans, GI17537241, Length=246, Percent_Identity=34.5528455284553, Blast_Score=123, Evalue=2e-28,
Organism=Drosophila melanogaster, GI19920442, Length=257, Percent_Identity=35.408560311284, Blast_Score=110, Evalue=2e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): Y041_METJA (Q60346)

Other databases:

- EMBL:   L77117
- PIR:   A64305
- RefSeq:   NP_247004.1
- ProteinModelPortal:   Q60346
- SMR:   Q60346
- GeneID:   1450879
- GenomeReviews:   L77117_GR
- KEGG:   mja:MJ_0041
- NMPDR:   fig|243232.1.peg.41
- TIGR:   MJ0041
- HOGENOM:   HBG512884
- OMA:   CNFTGKQ
- ProtClustDB:   PRK14554
- BioCyc:   MJAN243232:MJ_0041-MONOMER
- InterPro:   IPR005912
- InterPro:   IPR020103
- InterPro:   IPR004114
- TIGRFAMs:   TIGR01213

Pfam domain/function: PF02926 THUMP; SSF55120 PsdUridine_synth_cat_dom

EC number: NA

Molecular weight: Translated: 52927; Mature: 52796

Theoretical pI: Translated: 8.70; Mature: 8.70

Prosite motif: PS51165 THUMP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MASIINKQIISPTGRNMEIINYEILKKYPLCDRCFGRLYAKLLHTTNTERGRALKLYKAL
CCCHHHHHHCCCCCCCEEEEEHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCEEHHHHHH
ELEAKIKKAKEKGINYEEELELLKALAKSGVDEIRLEDIEIEKENCPWCRGIFNKQKMEK
HHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCEEEECEEECCCCCCHHHHHCCHHHHHH
LLNKAIELLKEYDFDTFLIGTHIPEEIKDLEKEIETEFMESIKQEFGREFGKMLAVRLDK
HHHHHHHHHHHCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
APDKEYPDIVVHINPYTEEIYLQINPLFIKGRYRKLVRGIPQTRWPCRKCRGKGCELCNY
CCCCCCCEEEEEECCCCEEEEEEEEEEEECHHHHHHHHCCCCCCCCHHHHCCCCCCEECC
TGKKYPISVEEIIAKPFLEATKGVDAKFHGAGREDIDVRMLGDGRPFVLEIKEPKIRKID
CCCCCCCCHHHHHHHHHHHHHCCCCCEECCCCCCCCEEEEECCCCCEEEEECCCCCEEEC
LNKIAEEINKDGRVEVLNLEFGVRKDKVIFKNTPHRKTYRALVECSDKITDEELKLLEKE
HHHHHHHHCCCCCEEEEEEEECCCCCCEEECCCCCHHHHHHHHHHHHCCCHHHHHHHHHH
LENRTIYQKTPKRVLHRRADLERIRKVYKVKTSKVDDNHFEMIIYCDGGLYIKELISGDD
HHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCHHHHHHHCCCC
GRTNPSVSSILNKNCICKELDVLKIHDNNLLEKG
CCCCCHHHHHHCCCCCCCCCCEEEECCCCCCCCC
>Mature Secondary Structure 
ASIINKQIISPTGRNMEIINYEILKKYPLCDRCFGRLYAKLLHTTNTERGRALKLYKAL
CCHHHHHHCCCCCCCEEEEEHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCEEHHHHHH
ELEAKIKKAKEKGINYEEELELLKALAKSGVDEIRLEDIEIEKENCPWCRGIFNKQKMEK
HHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCEEEECEEECCCCCCHHHHHCCHHHHHH
LLNKAIELLKEYDFDTFLIGTHIPEEIKDLEKEIETEFMESIKQEFGREFGKMLAVRLDK
HHHHHHHHHHHCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
APDKEYPDIVVHINPYTEEIYLQINPLFIKGRYRKLVRGIPQTRWPCRKCRGKGCELCNY
CCCCCCCEEEEEECCCCEEEEEEEEEEEECHHHHHHHHCCCCCCCCHHHHCCCCCCEECC
TGKKYPISVEEIIAKPFLEATKGVDAKFHGAGREDIDVRMLGDGRPFVLEIKEPKIRKID
CCCCCCCCHHHHHHHHHHHHHCCCCCEECCCCCCCCEEEEECCCCCEEEEECCCCCEEEC
LNKIAEEINKDGRVEVLNLEFGVRKDKVIFKNTPHRKTYRALVECSDKITDEELKLLEKE
HHHHHHHHCCCCCEEEEEEEECCCCCCEEECCCCCHHHHHHHHHHHHCCCHHHHHHHHHH
LENRTIYQKTPKRVLHRRADLERIRKVYKVKTSKVDDNHFEMIIYCDGGLYIKELISGDD
HHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCHHHHHHHCCCC
GRTNPSVSSILNKNCICKELDVLKIHDNNLLEKG
CCCCCHHHHHHCCCCCCCCCCEEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087