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The map label for this gene is 16273577

Identifier: 16273577

GI number: 16273577

Start: 1759981

End: 1761354

Strand: Direct

Name: 16273577

Synonym: HI1690

Alternate gene names: NA

Gene position: 1759981-1761354 (Clockwise)

Preceding gene: 16273576

Following gene: 16273581

Centisome position: 96.17

GC content: 37.7

Gene sequence:

>1374_bases
ATGACAACAAACAATAAACAGCGACAAACTTGGTCGAGCCGCCTCACTTATGTAATGACGGTCGCAGGCGCAACAGTCGG
TTTCGGTGCAACTTGGCGTTTCCCTTATCTTGTGGGTGAAAATGGTGGCGGTGCTTACGTTTTACTTTTCTGTATCGCAA
TGATTGTAATCGGTATCCCAATGATTTTAGTTGAAAACGTGATAGGTCGCCGCTTACGTGTAAATTCCATTGATGCATTC
GGCGATAAAATTCTCGACAAAGGAAAAGGCATTTCTAAATATTGGAAAATATTAGGTTATATGGGCTTACTCGGCGCATT
TGGCATTATGGCGTATTATATGGTGCTTGGTGGCTGGGTTATTTCTTATATCATTAGCCTAATCAGCGGTACCTTAGACA
TTTCAACCCCCATCACAAAAGACATTGCCAAAAATTTCTACGATCTTCACATCGGCAATAGCCCTTATGAAATTATATTC
TACACTCTCTTATTTGTTATCGTGAATTACATTATCTTGGCAAAAGGTATCATTGGTGGAATTGAACGTTCGGTAAAATA
TTTAATGCCATTACTATTTATCTTCTTAATTGGAATGGTAATTCGCAACGTAACATTACCGGGTGCAATGGAAGGCATTA
CATTCTATTTAAAACCAGATTTCAGCAAAATTACCCCACAATTATTTATCTTTGTTTTAGGGCAAGTCTTCTTCGCATTA
AGCCTTGGTTTTGGCGTATTAATTACCCTTTCCAGTTACTTAAATAAAGAAGAAAACTTAATCCACACCGCCGTAATTAC
AGGTTTCACCAACACAATTATTGCCGTACTTGCTGGCTTTATGATTTTCCCCTCACTTTTCACTTTTGGGATTGAACCAA
ACGCAGGGCCAACATTAGTATTCCAAAGTTTACCTATCGTATTTTCTCACTTATGGGCAGGCAAATTCTTTGCGATTATC
TTCTTCGGCTTATTATTAATTGCTGCGCTGACTACTTCCATCACAATTTATGAAGTGATCATTACAGCATTACAAGAAAA
GCTCAGAATGTGCCGTGGCAAAGCCATTGTCTTAACCCTTAGTGGCATTTTTCTATTAGGCAATATCCCTGCAATTTTAG
GCGATAATCTATGGAAAAACGTAACCATTTTCGGCAAAAGCATTTTTGATTTCTACGATTACGCCAGTGGAAATATTCTC
TTTATGCTGACCGCACTTGGCTGTGCTATTTTCGTTGGTTTCGTGTTAAAAGATGAAGCCAAAAAAGAACTTTCTTCAAC
AAAATATTCAACTTTCATCAAAATTTGGTTTAACTACGTGAAATTTGTTGTACCCTTGATCATCTTAGTTATCTTTATCA
GCAACCTGTTCTAA

Upstream 100 bases:

>100_bases
TATTGAAGATCTTTGTGAATATAAAGAAAAAGTTGAATTTTAATTTTGCGGTAAAACAACCTAATTATTTACCGCACTTT
TATTAAAAATAGGATAAAAA

Downstream 100 bases:

>100_bases
AAATTAAAAATGCGGTAAGGCGACTACATTACCGACACCGCTTTAATTTGAACATAAACATCTTGCCCAATAGCAAAACG
CAGTTCATTTTGCGCCCATT

Product: sodium-dependent transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 457; Mature: 456

Protein sequence:

>457_residues
MTTNNKQRQTWSSRLTYVMTVAGATVGFGATWRFPYLVGENGGGAYVLLFCIAMIVIGIPMILVENVIGRRLRVNSIDAF
GDKILDKGKGISKYWKILGYMGLLGAFGIMAYYMVLGGWVISYIISLISGTLDISTPITKDIAKNFYDLHIGNSPYEIIF
YTLLFVIVNYIILAKGIIGGIERSVKYLMPLLFIFLIGMVIRNVTLPGAMEGITFYLKPDFSKITPQLFIFVLGQVFFAL
SLGFGVLITLSSYLNKEENLIHTAVITGFTNTIIAVLAGFMIFPSLFTFGIEPNAGPTLVFQSLPIVFSHLWAGKFFAII
FFGLLLIAALTTSITIYEVIITALQEKLRMCRGKAIVLTLSGIFLLGNIPAILGDNLWKNVTIFGKSIFDFYDYASGNIL
FMLTALGCAIFVGFVLKDEAKKELSSTKYSTFIKIWFNYVKFVVPLIILVIFISNLF

Sequences:

>Translated_457_residues
MTTNNKQRQTWSSRLTYVMTVAGATVGFGATWRFPYLVGENGGGAYVLLFCIAMIVIGIPMILVENVIGRRLRVNSIDAF
GDKILDKGKGISKYWKILGYMGLLGAFGIMAYYMVLGGWVISYIISLISGTLDISTPITKDIAKNFYDLHIGNSPYEIIF
YTLLFVIVNYIILAKGIIGGIERSVKYLMPLLFIFLIGMVIRNVTLPGAMEGITFYLKPDFSKITPQLFIFVLGQVFFAL
SLGFGVLITLSSYLNKEENLIHTAVITGFTNTIIAVLAGFMIFPSLFTFGIEPNAGPTLVFQSLPIVFSHLWAGKFFAII
FFGLLLIAALTTSITIYEVIITALQEKLRMCRGKAIVLTLSGIFLLGNIPAILGDNLWKNVTIFGKSIFDFYDYASGNIL
FMLTALGCAIFVGFVLKDEAKKELSSTKYSTFIKIWFNYVKFVVPLIILVIFISNLF
>Mature_456_residues
TTNNKQRQTWSSRLTYVMTVAGATVGFGATWRFPYLVGENGGGAYVLLFCIAMIVIGIPMILVENVIGRRLRVNSIDAFG
DKILDKGKGISKYWKILGYMGLLGAFGIMAYYMVLGGWVISYIISLISGTLDISTPITKDIAKNFYDLHIGNSPYEIIFY
TLLFVIVNYIILAKGIIGGIERSVKYLMPLLFIFLIGMVIRNVTLPGAMEGITFYLKPDFSKITPQLFIFVLGQVFFALS
LGFGVLITLSSYLNKEENLIHTAVITGFTNTIIAVLAGFMIFPSLFTFGIEPNAGPTLVFQSLPIVFSHLWAGKFFAIIF
FGLLLIAALTTSITIYEVIITALQEKLRMCRGKAIVLTLSGIFLLGNIPAILGDNLWKNVTIFGKSIFDFYDYASGNILF
MLTALGCAIFVGFVLKDEAKKELSSTKYSTFIKIWFNYVKFVVPLIILVIFISNLF

Specific function: Putative sodium-dependent transporter

COG id: COG0733

COG function: function code R; Na+-dependent transporters of the SNF family

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family

Homologues:

Organism=Homo sapiens, GI188528618, Length=492, Percent_Identity=26.0162601626016, Blast_Score=148, Evalue=9e-36,
Organism=Homo sapiens, GI4507043, Length=389, Percent_Identity=29.0488431876607, Blast_Score=145, Evalue=1e-34,
Organism=Homo sapiens, GI21361581, Length=450, Percent_Identity=26, Blast_Score=132, Evalue=8e-31,
Organism=Homo sapiens, GI171184408, Length=459, Percent_Identity=25.7080610021786, Blast_Score=130, Evalue=2e-30,
Organism=Homo sapiens, GI171184406, Length=459, Percent_Identity=25.7080610021786, Blast_Score=130, Evalue=2e-30,
Organism=Homo sapiens, GI171184404, Length=459, Percent_Identity=25.7080610021786, Blast_Score=130, Evalue=2e-30,
Organism=Homo sapiens, GI289191351, Length=408, Percent_Identity=27.4509803921569, Blast_Score=130, Evalue=3e-30,
Organism=Homo sapiens, GI4557046, Length=408, Percent_Identity=27.4509803921569, Blast_Score=130, Evalue=3e-30,
Organism=Homo sapiens, GI289191377, Length=413, Percent_Identity=27.3607748184019, Blast_Score=130, Evalue=3e-30,
Organism=Homo sapiens, GI7657587, Length=462, Percent_Identity=25.974025974026, Blast_Score=128, Evalue=1e-29,
Organism=Homo sapiens, GI33354281, Length=304, Percent_Identity=29.6052631578947, Blast_Score=126, Evalue=4e-29,
Organism=Homo sapiens, GI58219014, Length=306, Percent_Identity=30.3921568627451, Blast_Score=123, Evalue=3e-28,
Organism=Homo sapiens, GI4507041, Length=510, Percent_Identity=24.7058823529412, Blast_Score=123, Evalue=3e-28,
Organism=Homo sapiens, GI51468073, Length=299, Percent_Identity=29.0969899665552, Blast_Score=122, Evalue=8e-28,
Organism=Homo sapiens, GI92859670, Length=432, Percent_Identity=27.5462962962963, Blast_Score=120, Evalue=3e-27,
Organism=Homo sapiens, GI5032097, Length=511, Percent_Identity=25.6360078277886, Blast_Score=117, Evalue=3e-26,
Organism=Homo sapiens, GI134304856, Length=383, Percent_Identity=27.9373368146214, Blast_Score=115, Evalue=7e-26,
Organism=Homo sapiens, GI194018524, Length=302, Percent_Identity=27.4834437086093, Blast_Score=114, Evalue=2e-25,
Organism=Homo sapiens, GI197276623, Length=345, Percent_Identity=26.6666666666667, Blast_Score=110, Evalue=3e-24,
Organism=Homo sapiens, GI54607094, Length=345, Percent_Identity=26.6666666666667, Blast_Score=110, Evalue=3e-24,
Organism=Homo sapiens, GI218563756, Length=504, Percent_Identity=25.3968253968254, Blast_Score=108, Evalue=1e-23,
Organism=Homo sapiens, GI11181770, Length=302, Percent_Identity=27.1523178807947, Blast_Score=107, Evalue=2e-23,
Organism=Homo sapiens, GI67782317, Length=396, Percent_Identity=26.2626262626263, Blast_Score=101, Evalue=2e-21,
Organism=Homo sapiens, GI67782313, Length=396, Percent_Identity=26.2626262626263, Blast_Score=100, Evalue=3e-21,
Organism=Homo sapiens, GI67782315, Length=396, Percent_Identity=26.2626262626263, Blast_Score=100, Evalue=5e-21,
Organism=Homo sapiens, GI12408638, Length=280, Percent_Identity=26.0714285714286, Blast_Score=95, Evalue=2e-19,
Organism=Homo sapiens, GI289191353, Length=241, Percent_Identity=29.8755186721992, Blast_Score=87, Evalue=4e-17,
Organism=Homo sapiens, GI21361693, Length=151, Percent_Identity=33.112582781457, Blast_Score=86, Evalue=1e-16,
Organism=Homo sapiens, GI300360519, Length=273, Percent_Identity=28.2051282051282, Blast_Score=85, Evalue=2e-16,
Organism=Homo sapiens, GI6005715, Length=203, Percent_Identity=30.0492610837438, Blast_Score=78, Evalue=1e-14,
Organism=Homo sapiens, GI226437581, Length=254, Percent_Identity=26.3779527559055, Blast_Score=73, Evalue=6e-13,
Organism=Homo sapiens, GI218563758, Length=271, Percent_Identity=27.6752767527675, Blast_Score=70, Evalue=3e-12,
Organism=Homo sapiens, GI197276625, Length=126, Percent_Identity=33.3333333333333, Blast_Score=70, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17555248, Length=403, Percent_Identity=28.287841191067, Blast_Score=137, Evalue=1e-32,
Organism=Caenorhabditis elegans, GI25146584, Length=403, Percent_Identity=25.5583126550869, Blast_Score=123, Evalue=2e-28,
Organism=Caenorhabditis elegans, GI17554804, Length=495, Percent_Identity=25.0505050505051, Blast_Score=100, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI17569475, Length=419, Percent_Identity=22.673031026253, Blast_Score=94, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI133952791, Length=217, Percent_Identity=29.9539170506912, Blast_Score=85, Evalue=6e-17,
Organism=Caenorhabditis elegans, GI71995588, Length=192, Percent_Identity=29.1666666666667, Blast_Score=74, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI71998244, Length=373, Percent_Identity=24.3967828418231, Blast_Score=73, Evalue=3e-13,
Organism=Drosophila melanogaster, GI45550877, Length=424, Percent_Identity=28.7735849056604, Blast_Score=144, Evalue=2e-34,
Organism=Drosophila melanogaster, GI45551183, Length=424, Percent_Identity=28.7735849056604, Blast_Score=143, Evalue=3e-34,
Organism=Drosophila melanogaster, GI24762620, Length=507, Percent_Identity=28.0078895463511, Blast_Score=140, Evalue=1e-33,
Organism=Drosophila melanogaster, GI24661428, Length=506, Percent_Identity=26.2845849802372, Blast_Score=131, Evalue=1e-30,
Organism=Drosophila melanogaster, GI17136952, Length=384, Percent_Identity=24.7395833333333, Blast_Score=126, Evalue=3e-29,
Organism=Drosophila melanogaster, GI281364394, Length=383, Percent_Identity=24.2819843342037, Blast_Score=122, Evalue=4e-28,
Organism=Drosophila melanogaster, GI28574704, Length=383, Percent_Identity=24.2819843342037, Blast_Score=122, Evalue=4e-28,
Organism=Drosophila melanogaster, GI17136950, Length=383, Percent_Identity=24.2819843342037, Blast_Score=122, Evalue=4e-28,
Organism=Drosophila melanogaster, GI28574702, Length=383, Percent_Identity=24.2819843342037, Blast_Score=122, Evalue=4e-28,
Organism=Drosophila melanogaster, GI19921936, Length=413, Percent_Identity=24.2130750605327, Blast_Score=120, Evalue=2e-27,
Organism=Drosophila melanogaster, GI24652942, Length=390, Percent_Identity=24.8717948717949, Blast_Score=119, Evalue=3e-27,
Organism=Drosophila melanogaster, GI45551088, Length=390, Percent_Identity=24.8717948717949, Blast_Score=119, Evalue=3e-27,
Organism=Drosophila melanogaster, GI281363702, Length=405, Percent_Identity=24.9382716049383, Blast_Score=111, Evalue=1e-24,
Organism=Drosophila melanogaster, GI24639514, Length=300, Percent_Identity=26, Blast_Score=109, Evalue=3e-24,
Organism=Drosophila melanogaster, GI24639516, Length=300, Percent_Identity=26, Blast_Score=109, Evalue=4e-24,
Organism=Drosophila melanogaster, GI221329674, Length=300, Percent_Identity=26, Blast_Score=109, Evalue=4e-24,
Organism=Drosophila melanogaster, GI24655079, Length=302, Percent_Identity=26.8211920529801, Blast_Score=107, Evalue=2e-23,
Organism=Drosophila melanogaster, GI24582567, Length=435, Percent_Identity=23.6781609195402, Blast_Score=106, Evalue=3e-23,
Organism=Drosophila melanogaster, GI281365034, Length=401, Percent_Identity=24.6882793017456, Blast_Score=103, Evalue=3e-22,
Organism=Drosophila melanogaster, GI19921352, Length=399, Percent_Identity=25.31328320802, Blast_Score=102, Evalue=6e-22,
Organism=Drosophila melanogaster, GI24584353, Length=399, Percent_Identity=25.31328320802, Blast_Score=102, Evalue=6e-22,
Organism=Drosophila melanogaster, GI281363700, Length=311, Percent_Identity=26.0450160771704, Blast_Score=101, Evalue=1e-21,
Organism=Drosophila melanogaster, GI24654186, Length=235, Percent_Identity=33.1914893617021, Blast_Score=97, Evalue=2e-20,
Organism=Drosophila melanogaster, GI24639853, Length=433, Percent_Identity=22.6327944572748, Blast_Score=92, Evalue=7e-19,
Organism=Drosophila melanogaster, GI281364136, Length=178, Percent_Identity=33.1460674157303, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24582569, Length=394, Percent_Identity=22.5888324873096, Blast_Score=69, Evalue=5e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): Y1690_HAEIN (P45320)

Other databases:

- EMBL:   L42023
- PIR:   H64136
- RefSeq:   NP_439832.1
- ProteinModelPortal:   P45320
- GeneID:   950500
- GenomeReviews:   L42023_GR
- KEGG:   hin:HI1690
- NMPDR:   fig|71421.1.peg.1603
- TIGR:   HI_1690
- HOGENOM:   HBG702834
- OMA:   IQTAVIT
- ProtClustDB:   CLSK870075
- BioCyc:   HINF71421:HI_1690-MONOMER
- InterPro:   IPR000175
- PANTHER:   PTHR11616
- PRINTS:   PR00176

Pfam domain/function: PF00209 SNF

EC number: NA

Molecular weight: Translated: 50757; Mature: 50625

Theoretical pI: Translated: 9.68; Mature: 9.68

Prosite motif: PS00610 NA_NEUROTRAN_SYMP_1; PS00754 NA_NEUROTRAN_SYMP_2; PS50267 NA_NEUROTRAN_SYMP_3

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0xee28038)-; HASH(0xedb1fbc)-; HASH(0xe76929c)-; HASH(0xecb5ea8)-; HASH(0xe6b4804)-; HASH(0xe14d7b0)-; HASH(0xef73e60)-; HASH(0xebb2dec)-; HASH(0xee88b24)-; HASH(0xe03e454)-; HASH(0xeda6f10)-; HASH(0xb16a06c)-;

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTNNKQRQTWSSRLTYVMTVAGATVGFGATWRFPYLVGENGGGAYVLLFCIAMIVIGIP
CCCCCHHHHHHHHHHHHHHEECCCCCCCCCEEECCEEEECCCCCHHHHHHHHHHHHHHHH
MILVENVIGRRLRVNSIDAFGDKILDKGKGISKYWKILGYMGLLGAFGIMAYYMVLGGWV
HHHHHHHHCCCEEECCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ISYIISLISGTLDISTPITKDIAKNFYDLHIGNSPYEIIFYTLLFVIVNYIILAKGIIGG
HHHHHHHHHCCCCCCCCHHHHHHCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
IERSVKYLMPLLFIFLIGMVIRNVTLPGAMEGITFYLKPDFSKITPQLFIFVLGQVFFAL
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHCEEEEECCCHHHHHHHHHHHHHHHHHHHH
SLGFGVLITLSSYLNKEENLIHTAVITGFTNTIIAVLAGFMIFPSLFTFGIEPNAGPTLV
HHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHH
FQSLPIVFSHLWAGKFFAIIFFGLLLIAALTTSITIYEVIITALQEKLRMCRGKAIVLTL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEE
SGIFLLGNIPAILGDNLWKNVTIFGKSIFDFYDYASGNILFMLTALGCAIFVGFVLKDEA
HHHHHHCCCHHHHCCHHHCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHH
KKELSSTKYSTFIKIWFNYVKFVVPLIILVIFISNLF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCH
>Mature Secondary Structure 
TTNNKQRQTWSSRLTYVMTVAGATVGFGATWRFPYLVGENGGGAYVLLFCIAMIVIGIP
CCCCHHHHHHHHHHHHHHEECCCCCCCCCEEECCEEEECCCCCHHHHHHHHHHHHHHHH
MILVENVIGRRLRVNSIDAFGDKILDKGKGISKYWKILGYMGLLGAFGIMAYYMVLGGWV
HHHHHHHHCCCEEECCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ISYIISLISGTLDISTPITKDIAKNFYDLHIGNSPYEIIFYTLLFVIVNYIILAKGIIGG
HHHHHHHHHCCCCCCCCHHHHHHCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
IERSVKYLMPLLFIFLIGMVIRNVTLPGAMEGITFYLKPDFSKITPQLFIFVLGQVFFAL
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHCEEEEECCCHHHHHHHHHHHHHHHHHHHH
SLGFGVLITLSSYLNKEENLIHTAVITGFTNTIIAVLAGFMIFPSLFTFGIEPNAGPTLV
HHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHH
FQSLPIVFSHLWAGKFFAIIFFGLLLIAALTTSITIYEVIITALQEKLRMCRGKAIVLTL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEE
SGIFLLGNIPAILGDNLWKNVTIFGKSIFDFYDYASGNILFMLTALGCAIFVGFVLKDEA
HHHHHHCCCHHHHCCHHHCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHH
KKELSSTKYSTFIKIWFNYVKFVVPLIILVIFISNLF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800