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The map label for this gene is sapB

Identifier: 16273528

GI number: 16273528

Start: 1704660

End: 1705625

Strand: Direct

Name: sapB

Synonym: HI1639

Alternate gene names: 16273528

Gene position: 1704660-1705625 (Clockwise)

Preceding gene: 16273527

Following gene: 16273529

Centisome position: 93.14

GC content: 35.09

Gene sequence:

>966_bases
ATGTTATGGTCGGTTCTTCGCCATATTCTGTGGGTGGCATTATTATTACTCGTATTATCGCTATTAGGCTTTGTCATTTT
ATTGCGCGATCCTCTTAATGCGAATCTTGTTACACAAAACATTTATATCGGCTATTTCCATTATTTAGGCACCTTGTTAC
AAGGTGATTTTGGCATTACCTATAACGGTGGAAAATCATTAATGAACCTTATTCTTACGGTTCTTCCTCCCACATTGGAA
CTTTGTTTCATTACATTGTTTTTGGCATTTATTTTTGGTTTGCCACTTGGCATTATAAGTGCGGTCAATTCTGAACAAGT
TTTTGCAAAAAGTTTACAAATCCTATCTTATGTAGGGCTATCTATTCCAATATTTTGGTTAGCCCCCATTTTACTGTATG
TTGCCGCGCTCTCACATTGGGAAATTGCCGCTATTGGACAATATAATTTGCTTTACGAAATTAAATCCATTACGGGATTT
CCTGTTATTGATATGTGGTTTATGGAAGTACCTTATCGTACAAAAATCGTACAAAACATATTGCAACATTTAGCCTTACC
AACATTGGTATTGTGTATTTTGCCAACAATGGAAATTATCCGCATTATTCATCAACGAGCAGAATATATTTTGAATCAAA
ATTTTTCTAAAGTAGCGACAACACGGGGTTGGTCAAAATGGAAAATTCTCCATCAATATGTATTCCGTAATACTTTTCCC
CTGCTTGTTCCACAAGTACCACGTGTATTCACATTAGTATTAACGCAATGTATGTTGGTAGAAACGGCTTTAGGTTGGCC
TGGCATTGGTCGTTGGTTAATTAATGCCGTAAATGAACAAGATTACAACAGCATTGCCGCAGGTGTAATTGTTATTGGTG
TATGTATTATTTTGATTGATACATTCACTAAAATATTCACTTTTATACTCGATCCATTTAAAAAGAAAGGTTGGTATGCA
AAATAA

Upstream 100 bases:

>100_bases
AACGAATTTTAGTCGCAAATAGTCGTGTGAAAGGAGTAAAAATGACGCCTTTTGGTAGCTTAGATTTTTCCACCTTATAT
TTTATTCAGGAGAAATACTA

Downstream 100 bases:

>100_bases
AGAACCTGATGAATTCCGCGAAAGCACCTCAATCTTTCAAATTTGGTTACGCTTTCGTCAAAATACCATCGCACTTTTTA
GCTTTTATTTATTAATCGCA

Product: peptide ABC transporter permease

Products: ADP; phosphate; peptides [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 321; Mature: 321

Protein sequence:

>321_residues
MLWSVLRHILWVALLLLVLSLLGFVILLRDPLNANLVTQNIYIGYFHYLGTLLQGDFGITYNGGKSLMNLILTVLPPTLE
LCFITLFLAFIFGLPLGIISAVNSEQVFAKSLQILSYVGLSIPIFWLAPILLYVAALSHWEIAAIGQYNLLYEIKSITGF
PVIDMWFMEVPYRTKIVQNILQHLALPTLVLCILPTMEIIRIIHQRAEYILNQNFSKVATTRGWSKWKILHQYVFRNTFP
LLVPQVPRVFTLVLTQCMLVETALGWPGIGRWLINAVNEQDYNSIAAGVIVIGVCIILIDTFTKIFTFILDPFKKKGWYA
K

Sequences:

>Translated_321_residues
MLWSVLRHILWVALLLLVLSLLGFVILLRDPLNANLVTQNIYIGYFHYLGTLLQGDFGITYNGGKSLMNLILTVLPPTLE
LCFITLFLAFIFGLPLGIISAVNSEQVFAKSLQILSYVGLSIPIFWLAPILLYVAALSHWEIAAIGQYNLLYEIKSITGF
PVIDMWFMEVPYRTKIVQNILQHLALPTLVLCILPTMEIIRIIHQRAEYILNQNFSKVATTRGWSKWKILHQYVFRNTFP
LLVPQVPRVFTLVLTQCMLVETALGWPGIGRWLINAVNEQDYNSIAAGVIVIGVCIILIDTFTKIFTFILDPFKKKGWYA
K
>Mature_321_residues
MLWSVLRHILWVALLLLVLSLLGFVILLRDPLNANLVTQNIYIGYFHYLGTLLQGDFGITYNGGKSLMNLILTVLPPTLE
LCFITLFLAFIFGLPLGIISAVNSEQVFAKSLQILSYVGLSIPIFWLAPILLYVAALSHWEIAAIGQYNLLYEIKSITGF
PVIDMWFMEVPYRTKIVQNILQHLALPTLVLCILPTMEIIRIIHQRAEYILNQNFSKVATTRGWSKWKILHQYVFRNTFP
LLVPQVPRVFTLVLTQCMLVETALGWPGIGRWLINAVNEQDYNSIAAGVIVIGVCIILIDTFTKIFTFILDPFKKKGWYA
K

Specific function: Involved in a peptide intake transport system that plays a role in the resistance to antimicrobial peptides

COG id: COG4168

COG function: function code V; ABC-type antimicrobial peptide transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain

Homologues:

Organism=Escherichia coli, GI1787550, Length=288, Percent_Identity=34.375, Blast_Score=214, Evalue=5e-57,
Organism=Escherichia coli, GI1789965, Length=274, Percent_Identity=25.5474452554745, Blast_Score=119, Evalue=2e-28,
Organism=Escherichia coli, GI1787761, Length=342, Percent_Identity=26.3157894736842, Blast_Score=91, Evalue=1e-19,
Organism=Escherichia coli, GI1787497, Length=283, Percent_Identity=24.7349823321555, Blast_Score=90, Evalue=2e-19,
Organism=Escherichia coli, GI1787053, Length=275, Percent_Identity=24, Blast_Score=89, Evalue=4e-19,
Organism=Escherichia coli, GI1789888, Length=280, Percent_Identity=22.1428571428571, Blast_Score=86, Evalue=3e-18,
Organism=Escherichia coli, GI1788504, Length=275, Percent_Identity=24.3636363636364, Blast_Score=62, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): SAPB_HAEIN (P45286)

Other databases:

- EMBL:   L42023
- PIR:   B64134
- RefSeq:   NP_439781.1
- GeneID:   950849
- GenomeReviews:   L42023_GR
- KEGG:   hin:HI1639
- NMPDR:   fig|71421.1.peg.1553
- TIGR:   HI_1639
- HOGENOM:   HBG724229
- OMA:   PTLELCF
- ProtClustDB:   CLSK870294
- BioCyc:   HINF71421:HI_1639-MONOMER
- InterPro:   IPR000515

Pfam domain/function: PF00528 BPD_transp_1

EC number: NA

Molecular weight: Translated: 36529; Mature: 36529

Theoretical pI: Translated: 9.22; Mature: 9.22

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0xe47fce4)-; HASH(0xe9ba590)-; HASH(0xdd1da60)-; HASH(0xb0a6b14)-; HASH(0xeab2d50)-; HASH(0xece8dd8)-; HASH(0xee5686c)-; HASH(0xece8dc0)-;

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLWSVLRHILWVALLLLVLSLLGFVILLRDPLNANLVTQNIYIGYFHYLGTLLQGDFGIT
CHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEHHHHHHHHHHHHHHHCCCCCEE
YNGGKSLMNLILTVLPPTLELCFITLFLAFIFGLPLGIISAVNSEQVFAKSLQILSYVGL
ECCHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHH
SIPIFWLAPILLYVAALSHWEIAAIGQYNLLYEIKSITGFPVIDMWFMEVPYRTKIVQNI
HHHHHHHHHHHHHHHHHCCCCEEEECCHHHHHHHHHCCCCCHHHHHHHHCCHHHHHHHHH
LQHLALPTLVLCILPTMEIIRIIHQRAEYILNQNFSKVATTRGWSKWKILHQYVFRNTFP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCHHHHHHHHHHHHHCCCC
LLVPQVPRVFTLVLTQCMLVETALGWPGIGRWLINAVNEQDYNSIAAGVIVIGVCIILID
HHHCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHH
TFTKIFTFILDPFKKKGWYAK
HHHHHHHHHHHHHHCCCCCCH
>Mature Secondary Structure
MLWSVLRHILWVALLLLVLSLLGFVILLRDPLNANLVTQNIYIGYFHYLGTLLQGDFGIT
CHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEHHHHHHHHHHHHHHHCCCCCEE
YNGGKSLMNLILTVLPPTLELCFITLFLAFIFGLPLGIISAVNSEQVFAKSLQILSYVGL
ECCHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHH
SIPIFWLAPILLYVAALSHWEIAAIGQYNLLYEIKSITGFPVIDMWFMEVPYRTKIVQNI
HHHHHHHHHHHHHHHHHCCCCEEEECCHHHHHHHHHCCCCCHHHHHHHHCCHHHHHHHHH
LQHLALPTLVLCILPTMEIIRIIHQRAEYILNQNFSKVATTRGWSKWKILHQYVFRNTFP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCHHHHHHHHHHHHHCCCC
LLVPQVPRVFTLVLTQCMLVETALGWPGIGRWLINAVNEQDYNSIAAGVIVIGVCIILID
HHHCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHH
TFTKIFTFILDPFKKKGWYAK
HHHHHHHHHHHHHHCCCCCCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; peptides [Periplasm]; H2O [C]

Specific reaction: ATP + peptides [Periplasm] + H2O = ADP + phosphate + peptides [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7542800