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The map label for this gene is hns

Identifier: 16273481

GI number: 16273481

Start: 1655765

End: 1656169

Strand: Direct

Name: hns

Synonym: HI1587

Alternate gene names: 16273481

Gene position: 1655765-1656169 (Clockwise)

Preceding gene: 16273477

Following gene: 16273482

Centisome position: 90.47

GC content: 36.3

Gene sequence:

>405_bases
ATGAACGAATTAGTAAGAGGTTTAACAAATCTTCGTAGTTTACGTGCAGCTGTACGTGAATTAACGTTAGAACAAGCAGA
AAATGCCCTAGAAAAATTACAAACAGCTATCGAAGAAAAACGTGCTAATGAAGCAGAATTAATTAAAGCAGAGACAGAGC
GAAAAGAGCGTTTAGCTAAATATAAAGAATTAATGGAAAAAGAAGGTATTACACCTGAAGAATTACACGAAATTTTTGGC
ACAAAAACTGTATCAATTCGAGCAAAACGTGCTCCACGCCCTGCAAAATATGCGTTTATTGATGAAAATGGCGAGCATAA
AACTTGGACGGGTCAAGGTCGCACACCACGCCCAATTCAAAATGCGTTGAACAAAGGTAAATCATTATCTGATTTCGAAA
TTTAA

Upstream 100 bases:

>100_bases
TTTCGACCATTTATTTAATAATAGATATTTACAATAAATTTTATTTTCTCTATTATTAAATAAATTTTCCCACATTTAAT
GTTATTTATTGAGGTTTATT

Downstream 100 bases:

>100_bases
TTTTTCTATTTGAAACTAGAACCTATTTTATGGGTTCTATTTTTTTATCTAAACATAGCACACAACATTATGATCGAAAA
AAAAATATTACTCACTGATT

Product: DNA-binding protein H-NS

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 134; Mature: 134

Protein sequence:

>134_residues
MNELVRGLTNLRSLRAAVRELTLEQAENALEKLQTAIEEKRANEAELIKAETERKERLAKYKELMEKEGITPEELHEIFG
TKTVSIRAKRAPRPAKYAFIDENGEHKTWTGQGRTPRPIQNALNKGKSLSDFEI

Sequences:

>Translated_134_residues
MNELVRGLTNLRSLRAAVRELTLEQAENALEKLQTAIEEKRANEAELIKAETERKERLAKYKELMEKEGITPEELHEIFG
TKTVSIRAKRAPRPAKYAFIDENGEHKTWTGQGRTPRPIQNALNKGKSLSDFEI
>Mature_134_residues
MNELVRGLTNLRSLRAAVRELTLEQAENALEKLQTAIEEKRANEAELIKAETERKERLAKYKELMEKEGITPEELHEIFG
TKTVSIRAKRAPRPAKYAFIDENGEHKTWTGQGRTPRPIQNALNKGKSLSDFEI

Specific function: Binds tightly to ds-DNA, increases its thermal stability and inhibits transcription

COG id: COG2916

COG function: function code R; DNA-binding protein H-NS

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the histone-like protein H-NS family

Homologues:

Organism=Escherichia coli, GI1789023, Length=136, Percent_Identity=47.0588235294118, Blast_Score=115, Evalue=8e-28,
Organism=Escherichia coli, GI1787489, Length=135, Percent_Identity=47.4074074074074, Blast_Score=114, Evalue=2e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): HNS_HAEIN (P43841)

Other databases:

- EMBL:   L42023
- PIR:   D64131
- RefSeq:   NP_439732.1
- ProteinModelPortal:   P43841
- GeneID:   950451
- GenomeReviews:   L42023_GR
- KEGG:   hin:HI1587
- TIGR:   HI_1587
- HOGENOM:   HBG740436
- OMA:   NTWLELM
- ProtClustDB:   CLSK808542
- BioCyc:   HINF71421:HI_1587-MONOMER
- GO:   GO:0005622
- GO:   GO:0006350
- InterPro:   IPR001801
- SMART:   SM00528

Pfam domain/function: PF00816 Histone_HNS

EC number: NA

Molecular weight: Translated: 15329; Mature: 15329

Theoretical pI: Translated: 9.53; Mature: 9.53

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNELVRGLTNLRSLRAAVRELTLEQAENALEKLQTAIEEKRANEAELIKAETERKERLAK
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHH
YKELMEKEGITPEELHEIFGTKTVSIRAKRAPRPAKYAFIDENGEHKTWTGQGRTPRPIQ
HHHHHHHCCCCHHHHHHHHCCCCCEEEECCCCCCCCEEEECCCCCCCCCCCCCCCCHHHH
NALNKGKSLSDFEI
HHHHCCCCCCCCCC
>Mature Secondary Structure
MNELVRGLTNLRSLRAAVRELTLEQAENALEKLQTAIEEKRANEAELIKAETERKERLAK
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHH
YKELMEKEGITPEELHEIFGTKTVSIRAKRAPRPAKYAFIDENGEHKTWTGQGRTPRPIQ
HHHHHHHCCCCHHHHHHHHCCCCCEEEECCCCCCCCEEEECCCCCCCCCCCCCCCCHHHH
NALNKGKSLSDFEI
HHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800