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The map label for this gene is argS [H]

Identifier: 16273477

GI number: 16273477

Start: 1649297

End: 1651030

Strand: Direct

Name: argS [H]

Synonym: HI1583

Alternate gene names: 16273477

Gene position: 1649297-1651030 (Clockwise)

Preceding gene: 16273473

Following gene: 16273481

Centisome position: 90.12

GC content: 36.97

Gene sequence:

>1734_bases
GTGAATATTCAATCTATTCTATCCGATAAAATTAAACAAGCGATGATTCTTGCAGGTGCTGATCAATCTTGCGATGCGCT
TATTCGTCAATCAGGAAAACCACAATTTGGCGATTATCAAGCCAATGGCATTATGGCTGCGGCAAAAAAATTAGGTTTAA
ATCCACGAGAATTTGCTCAAAAAGTTTTAGACAATCTTCAACTATCTGATATTGCAGAAAAATTAGAAATCGCAGGTCCA
GGTTTTATCAATATTTTCTTAAATCCAACTTGGCTAACAACTGAAATTTCAGCTGCACTTTCCCACAAAAATTTAGGTAT
TCAAGCTACCAATAAACAAACAGTTGTGATTGATTATTCATCTCCAAACGTAGCAAAAGAAATGCACGTAGGTCATTTAC
GCTCTACGATAATCGGCGATGCTGTAGCCAGAACCCTTGAGTTTTTAGGTCACAATGTCATCCGAGCTAACCACGTAGGC
GACTGGGGAACGCAATTCGGAATGCTTATTGCTTATCTTGAAAAAATGCAAAACGAGCATGCGAGTGAAATGGAATTACA
AGATCTTGAAGCCTTTTATCGCGAAGCCAAAAAACACTACGATGAAGATGAAGTATTCGCAGAAAAAGCGCGTAATTATG
TTGTGAAATTACAAAGTGGAGATGAATATTGTCGAACGATGTGGAAACGTTTAGTCGATATCACTATGCAACAAAATCAG
CACAACTATGCTCGCTTAAACGTGACTTTAACCGAAAAAGATGTAATGGGCGAAAGTCTTTATAATCCTATGTTACCAAG
CATTGTAAAAGATCTTAAAAAACAAGGTTTGGCTGTGGAAAATGATGGTGCATTGGTTGTTTATTTAGATGAATTTAAAA
ATAAAGATGGCGACCCAATGGGTGTAATCGTTCAAAAAAAAGACGGCGGTTTCCTTTATACTACAACCGATATTGCTGCA
GCAAAATATCGTTATGAAACATTAAAAGCTAATCGCGCCCTTGTTTTTTCAGATACTCGCCAAAGCCAACATATGCAACA
AGCTTGGTTAATTACTCGTAAAGCAGGTTATGTACCAGATAGTTTCTCGTTAGAGCATAAAAACTTTGGGATGATGCTTG
GTAAAGATGGCAAACCATTTAAAACCCGTACTGGCGGCACAGTGAAATTGGCCGATCTATTAGATGAAGCCATTGAACGC
GCCACTGTATTAATTAATGAAAAAAATACCAATTTATCTAATGATGAAAAAGAAGCTGTGATTGAGGCTGTCGGTATTGG
TGCGGTGAAATATGCCGATCTCTCCAAAAACCGTACTACTGATTACGTTTTTGATTGGGATAATATGTTAAGTTTCGAAG
GTAACACGGCACCTTATATGCAATATGCCTACACCCGTATTCGTTCGATCTTTAATAAAACAGATATAAATTCAACCGCA
CTTTTGGCTGCACCTTTAACTATTAAAGATGATAAAGAAAGAACGCTTGCTATTAAACTTCTACAATTTGAAGAAGCCGT
GCAAACTGTCGGAAAAGAAGGCACGCCGCACGTGCTTTGTGCTTATTTATATGAACTTGCTGGCATCTTCTCGTCATTCT
ACGAACATTGTCCAATTTTAAATGCTGAAGATGAATCTATAAAATTAAGTCGTTTGAAATTAGCATTATTAACGGAAAAA
ACCTTAAAACAGGGTTTAACGTTACTCGGTATTAAAACCGTAGAAAAAATGTAA

Upstream 100 bases:

>100_bases
ATTTTCCTGTAAATTTGTCATTTTGTCCCTTTGAGAAATATACAAAGAACGGTATCATAACCGATTATTTTTATTATTCA
ATTTGAACATAGGAAAAAAC

Downstream 100 bases:

>100_bases
TTTAGATAATTAAAATCCCTTTCTCAGGAAAGGGATTTTTTATACTTGTTTACTGAATAAAAAAAAGCCCCATTGGGGCA
CTACTCGGAAAGCAAAATAG

Product: arginyl-tRNA synthetase

Products: NA

Alternate protein names: Arginine--tRNA ligase; ArgRS [H]

Number of amino acids: Translated: 577; Mature: 577

Protein sequence:

>577_residues
MNIQSILSDKIKQAMILAGADQSCDALIRQSGKPQFGDYQANGIMAAAKKLGLNPREFAQKVLDNLQLSDIAEKLEIAGP
GFINIFLNPTWLTTEISAALSHKNLGIQATNKQTVVIDYSSPNVAKEMHVGHLRSTIIGDAVARTLEFLGHNVIRANHVG
DWGTQFGMLIAYLEKMQNEHASEMELQDLEAFYREAKKHYDEDEVFAEKARNYVVKLQSGDEYCRTMWKRLVDITMQQNQ
HNYARLNVTLTEKDVMGESLYNPMLPSIVKDLKKQGLAVENDGALVVYLDEFKNKDGDPMGVIVQKKDGGFLYTTTDIAA
AKYRYETLKANRALVFSDTRQSQHMQQAWLITRKAGYVPDSFSLEHKNFGMMLGKDGKPFKTRTGGTVKLADLLDEAIER
ATVLINEKNTNLSNDEKEAVIEAVGIGAVKYADLSKNRTTDYVFDWDNMLSFEGNTAPYMQYAYTRIRSIFNKTDINSTA
LLAAPLTIKDDKERTLAIKLLQFEEAVQTVGKEGTPHVLCAYLYELAGIFSSFYEHCPILNAEDESIKLSRLKLALLTEK
TLKQGLTLLGIKTVEKM

Sequences:

>Translated_577_residues
MNIQSILSDKIKQAMILAGADQSCDALIRQSGKPQFGDYQANGIMAAAKKLGLNPREFAQKVLDNLQLSDIAEKLEIAGP
GFINIFLNPTWLTTEISAALSHKNLGIQATNKQTVVIDYSSPNVAKEMHVGHLRSTIIGDAVARTLEFLGHNVIRANHVG
DWGTQFGMLIAYLEKMQNEHASEMELQDLEAFYREAKKHYDEDEVFAEKARNYVVKLQSGDEYCRTMWKRLVDITMQQNQ
HNYARLNVTLTEKDVMGESLYNPMLPSIVKDLKKQGLAVENDGALVVYLDEFKNKDGDPMGVIVQKKDGGFLYTTTDIAA
AKYRYETLKANRALVFSDTRQSQHMQQAWLITRKAGYVPDSFSLEHKNFGMMLGKDGKPFKTRTGGTVKLADLLDEAIER
ATVLINEKNTNLSNDEKEAVIEAVGIGAVKYADLSKNRTTDYVFDWDNMLSFEGNTAPYMQYAYTRIRSIFNKTDINSTA
LLAAPLTIKDDKERTLAIKLLQFEEAVQTVGKEGTPHVLCAYLYELAGIFSSFYEHCPILNAEDESIKLSRLKLALLTEK
TLKQGLTLLGIKTVEKM
>Mature_577_residues
MNIQSILSDKIKQAMILAGADQSCDALIRQSGKPQFGDYQANGIMAAAKKLGLNPREFAQKVLDNLQLSDIAEKLEIAGP
GFINIFLNPTWLTTEISAALSHKNLGIQATNKQTVVIDYSSPNVAKEMHVGHLRSTIIGDAVARTLEFLGHNVIRANHVG
DWGTQFGMLIAYLEKMQNEHASEMELQDLEAFYREAKKHYDEDEVFAEKARNYVVKLQSGDEYCRTMWKRLVDITMQQNQ
HNYARLNVTLTEKDVMGESLYNPMLPSIVKDLKKQGLAVENDGALVVYLDEFKNKDGDPMGVIVQKKDGGFLYTTTDIAA
AKYRYETLKANRALVFSDTRQSQHMQQAWLITRKAGYVPDSFSLEHKNFGMMLGKDGKPFKTRTGGTVKLADLLDEAIER
ATVLINEKNTNLSNDEKEAVIEAVGIGAVKYADLSKNRTTDYVFDWDNMLSFEGNTAPYMQYAYTRIRSIFNKTDINSTA
LLAAPLTIKDDKERTLAIKLLQFEEAVQTVGKEGTPHVLCAYLYELAGIFSSFYEHCPILNAEDESIKLSRLKLALLTEK
TLKQGLTLLGIKTVEKM

Specific function: Unknown

COG id: COG0018

COG function: function code J; Arginyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Homo sapiens, GI15149476, Length=600, Percent_Identity=37.6666666666667, Blast_Score=384, Evalue=1e-106,
Organism=Homo sapiens, GI197100773, Length=595, Percent_Identity=28.9075630252101, Blast_Score=206, Evalue=4e-53,
Organism=Escherichia coli, GI1788184, Length=577, Percent_Identity=71.4038128249567, Blast_Score=883, Evalue=0.0,
Organism=Caenorhabditis elegans, GI71985061, Length=595, Percent_Identity=40.3361344537815, Blast_Score=395, Evalue=1e-110,
Organism=Caenorhabditis elegans, GI71985068, Length=563, Percent_Identity=40.6749555950266, Blast_Score=382, Evalue=1e-106,
Organism=Caenorhabditis elegans, GI17532153, Length=490, Percent_Identity=26.734693877551, Blast_Score=144, Evalue=9e-35,
Organism=Saccharomyces cerevisiae, GI6320548, Length=545, Percent_Identity=34.6788990825688, Blast_Score=265, Evalue=2e-71,
Organism=Saccharomyces cerevisiae, GI6321883, Length=522, Percent_Identity=29.5019157088123, Blast_Score=229, Evalue=1e-60,
Organism=Drosophila melanogaster, GI18859963, Length=566, Percent_Identity=38.339222614841, Blast_Score=384, Evalue=1e-106,
Organism=Drosophila melanogaster, GI28571570, Length=477, Percent_Identity=30.6079664570231, Blast_Score=177, Evalue=2e-44,

Paralogues:

None

Copy number: 789 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 800 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001412
- InterPro:   IPR001278
- InterPro:   IPR015945
- InterPro:   IPR005148
- InterPro:   IPR008909
- InterPro:   IPR014729
- InterPro:   IPR009080 [H]

Pfam domain/function: PF03485 Arg_tRNA_synt_N; PF05746 DALR_1; PF00750 tRNA-synt_1d [H]

EC number: =6.1.1.19 [H]

Molecular weight: Translated: 64733; Mature: 64733

Theoretical pI: Translated: 6.39; Mature: 6.39

Prosite motif: PS00178 AA_TRNA_LIGASE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNIQSILSDKIKQAMILAGADQSCDALIRQSGKPQFGDYQANGIMAAAKKLGLNPREFAQ
CCHHHHHHHHHHHHHEEECCCHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHCCCHHHHHH
KVLDNLQLSDIAEKLEIAGPGFINIFLNPTWLTTEISAALSHKNLGIQATNKQTVVIDYS
HHHHCCCHHHHHHHHHHCCCCEEEEEECCEEEHHHHHHHHHHCCCCEEECCCEEEEEECC
SPNVAKEMHVGHLRSTIIGDAVARTLEFLGHNVIRANHVGDWGTQFGMLIAYLEKMQNEH
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCHHHHHHHHHHHHHHHHHCC
ASEMELQDLEAFYREAKKHYDEDEVFAEKARNYVVKLQSGDEYCRTMWKRLVDITMQQNQ
CHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHHHHHHCCC
HNYARLNVTLTEKDVMGESLYNPMLPSIVKDLKKQGLAVENDGALVVYLDEFKNKDGDPM
CCEEEEEEEEEHHHHHHHHHHCCHHHHHHHHHHHCCCEEECCCEEEEEEHHHCCCCCCCE
GVIVQKKDGGFLYTTTDIAAAKYRYETLKANRALVFSDTRQSQHMQQAWLITRKAGYVPD
EEEEEECCCCEEEEECHHHHHHHHHHHHHCCCEEEEECCHHHHHHHHHHHHHHCCCCCCC
SFSLEHKNFGMMLGKDGKPFKTRTGGTVKLADLLDEAIERATVLINEKNTNLSNDEKEAV
CCCCCCCCCCEEECCCCCCCEECCCCEEEHHHHHHHHHHHHEEEEECCCCCCCCCHHHHH
IEAVGIGAVKYADLSKNRTTDYVFDWDNMLSFEGNTAPYMQYAYTRIRSIFNKTDINSTA
HHHHCCCCEEEECCCCCCCCCEEEECCCEEECCCCCCHHHHHHHHHHHHHHHHCCCCCCE
LLAAPLTIKDDKERTLAIKLLQFEEAVQTVGKEGTPHVLCAYLYELAGIFSSFYEHCPIL
EEEECEEECCCCCCEEHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCC
NAEDESIKLSRLKLALLTEKTLKQGLTLLGIKTVEKM
CCCCCCEEHHHHHHHHHHHHHHHCCCEEEEHHHHHCC
>Mature Secondary Structure
MNIQSILSDKIKQAMILAGADQSCDALIRQSGKPQFGDYQANGIMAAAKKLGLNPREFAQ
CCHHHHHHHHHHHHHEEECCCHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHCCCHHHHHH
KVLDNLQLSDIAEKLEIAGPGFINIFLNPTWLTTEISAALSHKNLGIQATNKQTVVIDYS
HHHHCCCHHHHHHHHHHCCCCEEEEEECCEEEHHHHHHHHHHCCCCEEECCCEEEEEECC
SPNVAKEMHVGHLRSTIIGDAVARTLEFLGHNVIRANHVGDWGTQFGMLIAYLEKMQNEH
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCHHHHHHHHHHHHHHHHHCC
ASEMELQDLEAFYREAKKHYDEDEVFAEKARNYVVKLQSGDEYCRTMWKRLVDITMQQNQ
CHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHHHHHHCCC
HNYARLNVTLTEKDVMGESLYNPMLPSIVKDLKKQGLAVENDGALVVYLDEFKNKDGDPM
CCEEEEEEEEEHHHHHHHHHHCCHHHHHHHHHHHCCCEEECCCEEEEEEHHHCCCCCCCE
GVIVQKKDGGFLYTTTDIAAAKYRYETLKANRALVFSDTRQSQHMQQAWLITRKAGYVPD
EEEEEECCCCEEEEECHHHHHHHHHHHHHCCCEEEEECCHHHHHHHHHHHHHHCCCCCCC
SFSLEHKNFGMMLGKDGKPFKTRTGGTVKLADLLDEAIERATVLINEKNTNLSNDEKEAV
CCCCCCCCCCEEECCCCCCCEECCCCEEEHHHHHHHHHHHHEEEEECCCCCCCCCHHHHH
IEAVGIGAVKYADLSKNRTTDYVFDWDNMLSFEGNTAPYMQYAYTRIRSIFNKTDINSTA
HHHHCCCCEEEECCCCCCCCCEEEECCCEEECCCCCCHHHHHHHHHHHHHHHHCCCCCCE
LLAAPLTIKDDKERTLAIKLLQFEEAVQTVGKEGTPHVLCAYLYELAGIFSSFYEHCPIL
EEEECEEECCCCCCEEHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCC
NAEDESIKLSRLKLALLTEKTLKQGLTLLGIKTVEKM
CCCCCCEEHHHHHHHHHHHHHHHCCCEEEEHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA