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The map label for this gene is murZ [H]

Identifier: 16273009

GI number: 16273009

Start: 1147762

End: 1149036

Strand: Reverse

Name: murZ [H]

Synonym: HI1081

Alternate gene names: 16273009

Gene position: 1149036-1147762 (Counterclockwise)

Preceding gene: 16273010

Following gene: 16273008

Centisome position: 62.78

GC content: 40.39

Gene sequence:

>1275_bases
ATGGATAAATTTCGTGTTTATGGGCAATCTCGTTTAAGTGGAAGTGTGAATATTTCAGGCGCAAAAAACGCCGCACTTCC
AATTCTTTTTGCGGCTATTTTAGCGACAGAACCTGTTAAATTGACAAATGTTCCCGAACTTAAAGATATTGAAACTACTT
TGAAAATTTTGCGTCAATTAGGCGTGGTTGTAGATCGTGATGCAACTGGTGCAGTTTTATTAGATGCCTCTAATATCAAT
CATTTCACTGCACCTTATGAATTGGTTAAAACTATGCGAGCTTCAATTTGGGCATTGGCACCTTTAGTCGCTCGTTTCCA
TCAAGGTCAAGTATCATTACCTGGAGGTTGTTCTATTGGGGCTAGACCTGTTGATCTCCATATTAGCGGTTTAGAAAAAT
TAGGTGCGGATATTGTTCTTGAAGAAGGATATGTAAAAGCACAAGTATCGGATCGTCTTGTGGGAACTCGTATTGTAATA
GAAAAAGTAAGTGTAGGCGCCACTTTATCTATTATGATGGCAGCAACCCTTGCGAAAGGTACGACTGTTATTGAAAACGC
CGCTCGTGAGCCTGAAATTGTTGATACCGCCGATTTCCTTAATAAAATGGGTGCGAAAATAACAGGTGCAGGATCTGCTC
ACATCACGATTGAAGGTGTTGAACGTTTAACTGGTTGTGAGCACAGTGTCGTGCCAGATCGCATTGAAACGGGTACATTC
TTAATTGCTGCAGCAATTTCGGGCGGTTGTGTTGTTTGTCAAAATACTAAAGCGGATACTTTAGATGCCGTAATTGATAA
ACTCCGTGAAGCTGGTGCGCAAGTTGATGTAACTGAAAATAGCATTACTTTAGATATGCTTGGTAATCGCCCTAAAGCAG
TGAATATTCGTACTGCACCACATCCAGGGTTCCCAACTGATATGCAGGCTCAATTTACTTTATTAAATATGGTGGCAGAA
GGTACAAGCATTATCACTGAAACGATTTTTGAAAATCGTTTTATGCATATTCCTGAATTAATTCGTATGGGTGGTAAAGC
TGAAATTGAAGGGAATACAGCGGTATGTCACGGGGTTGAACAATTGTCTGGCACAGAGGTAATAGCGACAGATTTACGCG
CTTCAATCAGTTTAGTGCTTGCAGGTTGTATCGCAACGGGTGAAACCATTGTAGATCGTATTTATCATATCGATCGTGGT
TATGAACATATCGAAGATAAATTACGTGGCCTAGGTGCGAAAATTGAACGTTTTTCTGGAAGTGATGAAGCGTAA

Upstream 100 bases:

>100_bases
TTTAGTACTGGTGAAATTCACGCTCTAACCATCAAAACTTATACCGTAGAAAAATGGAAACGCGATCGTGCATTAAACCA
GTTTAATTAAGGATTTAAAA

Downstream 100 bases:

>100_bases
TTAGATACGCTGCTTTTCTATTAGACATTACAAGTTTATTTATAATCTTAAATTTCTATTAATGCCTTTCTTTAGAAAGG
CATTTTTTTACTGAAATTTT

Product: UDP-N-acetylglucosamine 1-carboxyvinyltransferase

Products: NA

Alternate protein names: Enoylpyruvate transferase; UDP-N-acetylglucosamine enolpyruvyl transferase; EPT [H]

Number of amino acids: Translated: 424; Mature: 424

Protein sequence:

>424_residues
MDKFRVYGQSRLSGSVNISGAKNAALPILFAAILATEPVKLTNVPELKDIETTLKILRQLGVVVDRDATGAVLLDASNIN
HFTAPYELVKTMRASIWALAPLVARFHQGQVSLPGGCSIGARPVDLHISGLEKLGADIVLEEGYVKAQVSDRLVGTRIVI
EKVSVGATLSIMMAATLAKGTTVIENAAREPEIVDTADFLNKMGAKITGAGSAHITIEGVERLTGCEHSVVPDRIETGTF
LIAAAISGGCVVCQNTKADTLDAVIDKLREAGAQVDVTENSITLDMLGNRPKAVNIRTAPHPGFPTDMQAQFTLLNMVAE
GTSIITETIFENRFMHIPELIRMGGKAEIEGNTAVCHGVEQLSGTEVIATDLRASISLVLAGCIATGETIVDRIYHIDRG
YEHIEDKLRGLGAKIERFSGSDEA

Sequences:

>Translated_424_residues
MDKFRVYGQSRLSGSVNISGAKNAALPILFAAILATEPVKLTNVPELKDIETTLKILRQLGVVVDRDATGAVLLDASNIN
HFTAPYELVKTMRASIWALAPLVARFHQGQVSLPGGCSIGARPVDLHISGLEKLGADIVLEEGYVKAQVSDRLVGTRIVI
EKVSVGATLSIMMAATLAKGTTVIENAAREPEIVDTADFLNKMGAKITGAGSAHITIEGVERLTGCEHSVVPDRIETGTF
LIAAAISGGCVVCQNTKADTLDAVIDKLREAGAQVDVTENSITLDMLGNRPKAVNIRTAPHPGFPTDMQAQFTLLNMVAE
GTSIITETIFENRFMHIPELIRMGGKAEIEGNTAVCHGVEQLSGTEVIATDLRASISLVLAGCIATGETIVDRIYHIDRG
YEHIEDKLRGLGAKIERFSGSDEA
>Mature_424_residues
MDKFRVYGQSRLSGSVNISGAKNAALPILFAAILATEPVKLTNVPELKDIETTLKILRQLGVVVDRDATGAVLLDASNIN
HFTAPYELVKTMRASIWALAPLVARFHQGQVSLPGGCSIGARPVDLHISGLEKLGADIVLEEGYVKAQVSDRLVGTRIVI
EKVSVGATLSIMMAATLAKGTTVIENAAREPEIVDTADFLNKMGAKITGAGSAHITIEGVERLTGCEHSVVPDRIETGTF
LIAAAISGGCVVCQNTKADTLDAVIDKLREAGAQVDVTENSITLDMLGNRPKAVNIRTAPHPGFPTDMQAQFTLLNMVAE
GTSIITETIFENRFMHIPELIRMGGKAEIEGNTAVCHGVEQLSGTEVIATDLRASISLVLAGCIATGETIVDRIYHIDRG
YEHIEDKLRGLGAKIERFSGSDEA

Specific function: Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine [H]

COG id: COG0766

COG function: function code M; UDP-N-acetylglucosamine enolpyruvyl transferase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the EPSP synthase family. MurA subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789580, Length=420, Percent_Identity=72.3809523809524, Blast_Score=624, Evalue=1e-180,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001986
- InterPro:   IPR013792
- InterPro:   IPR005750 [H]

Pfam domain/function: PF00275 EPSP_synthase [H]

EC number: =2.5.1.7 [H]

Molecular weight: Translated: 45188; Mature: 45188

Theoretical pI: Translated: 5.31; Mature: 5.31

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDKFRVYGQSRLSGSVNISGAKNAALPILFAAILATEPVKLTNVPELKDIETTLKILRQL
CCCEEEECCCCCCCEEEECCCCCCHHHHHHHHHHHCCCEEECCCCCHHHHHHHHHHHHHH
GVVVDRDATGAVLLDASNINHFTAPYELVKTMRASIWALAPLVARFHQGQVSLPGGCSIG
CCEEECCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEECCCCCCCC
ARPVDLHISGLEKLGADIVLEEGYVKAQVSDRLVGTRIVIEKVSVGATLSIMMAATLAKG
CEEEEEEECCHHHCCCCEEEECCEEEEEHHCCHHHHEEEEEECCCCCHHHHHHHHHHHCC
TTVIENAAREPEIVDTADFLNKMGAKITGAGSAHITIEGVERLTGCEHSVVPDRIETGTF
CHHHHHCCCCCCCCCHHHHHHHHCCEEECCCCEEEEEEEHHHHCCCCCCCCCCCCCCCCE
LIAAAISGGCVVCQNTKADTLDAVIDKLREAGAQVDVTENSITLDMLGNRPKAVNIRTAP
EEEEECCCCEEEECCCCCHHHHHHHHHHHHCCCEEEECCCEEEEEECCCCCCEEEEEECC
HPGFPTDMQAQFTLLNMVAEGTSIITETIFENRFMHIPELIRMGGKAEIEGNTAVCHGVE
CCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHCCCCCCHHHHHCCCCEEECCCHHHHHHHH
QLSGTEVIATDLRASISLVLAGCIATGETIVDRIYHIDRGYEHIEDKLRGLGAKIERFSG
HCCCCEEEHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCHHHHHHHHHHCCCHHHHCCC
SDEA
CCCC
>Mature Secondary Structure
MDKFRVYGQSRLSGSVNISGAKNAALPILFAAILATEPVKLTNVPELKDIETTLKILRQL
CCCEEEECCCCCCCEEEECCCCCCHHHHHHHHHHHCCCEEECCCCCHHHHHHHHHHHHHH
GVVVDRDATGAVLLDASNINHFTAPYELVKTMRASIWALAPLVARFHQGQVSLPGGCSIG
CCEEECCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEECCCCCCCC
ARPVDLHISGLEKLGADIVLEEGYVKAQVSDRLVGTRIVIEKVSVGATLSIMMAATLAKG
CEEEEEEECCHHHCCCCEEEECCEEEEEHHCCHHHHEEEEEECCCCCHHHHHHHHHHHCC
TTVIENAAREPEIVDTADFLNKMGAKITGAGSAHITIEGVERLTGCEHSVVPDRIETGTF
CHHHHHCCCCCCCCCHHHHHHHHCCEEECCCCEEEEEEEHHHHCCCCCCCCCCCCCCCCE
LIAAAISGGCVVCQNTKADTLDAVIDKLREAGAQVDVTENSITLDMLGNRPKAVNIRTAP
EEEEECCCCEEEECCCCCHHHHHHHHHHHHCCCEEEECCCEEEEEECCCCCCEEEEEECC
HPGFPTDMQAQFTLLNMVAEGTSIITETIFENRFMHIPELIRMGGKAEIEGNTAVCHGVE
CCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHCCCCCCHHHHHCCCCEEECCCHHHHHHHH
QLSGTEVIATDLRASISLVLAGCIATGETIVDRIYHIDRGYEHIEDKLRGLGAKIERFSG
HCCCCEEEHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCHHHHHHHHHHCCCHHHHCCC
SDEA
CCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA