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The map label for this gene is degS

Identifier: 16272882

GI number: 16272882

Start: 1004486

End: 1005508

Strand: Direct

Name: degS

Synonym: HI0945

Alternate gene names: 16272882

Gene position: 1004486-1005508 (Clockwise)

Preceding gene: 16272881

Following gene: 16272891

Centisome position: 54.89

GC content: 39.3

Gene sequence:

>1023_bases
ATGCTTAAAAAACTTTTCCATTCCGCACTTTGGGGCTTGGCTGCTGCGGGCGTGATTTTGTTTGCGGTTCCAAGACTGAA
TAACAGCAATATCTTCACTTCAGACGATATTATATCGTTCAAAAATGCTGTGCGTATTGCCTCTCCAGCAGTAGTGAATG
TTTATAACCGCTCTTTTTCTTCCGCCAGCATTAATGATAATGATCAGCTACAAGTGAATAACTTAGGTTCTGGTGTGATT
ATGAGTAAAGATGGCTATATTCTGACGAATAAACACCTCATCCAAAATGCAGATCAAATTGTAGTAGCGTTGCAAAATGG
AAATATTTTTGAGGCCAGTCTTGTTGGTTCAGATGATCTCACTGATCTCGCTGTTCTTAAAATTCGTGCAGATAATCTTT
CAACTATTCCACAAAATTCAGCGCGTCAAGCTCACGTCGGCGATGTGGTATTAGCAATCGGTAATCCCTACAACTTAGGA
CAAAGCGTGTCTCAAGGAATCATTAGCGCAATCGGTCGTAATGCGGTAGGCGATTCGGTGGGCAGACAAAATTTTATTCA
AACTGATGCTTCAATTAATCGCGGAAACTCAGGCGGTGCCTTAATTAACTCTGCTGGGGAATTGGTTGGAATTAGCACGC
TAAGTATTGGCAAAACCGCCAATGAAATCGCAGAAGGACTAAATTTTGCCATTCCAATAGATATTGCAAATGATGTACTA
CGTAAAATTATGCGTGATGGACGTGTGATTCGAGGTTATTTTGGTGTACAAAGTGATATTAGTTCAAGTAGTGAAGAAGG
CATAGTTATCACAGATGTAAGTCCGAACAGCCCAGCTGCGAAATCAGGTATTCAAGTTGGCGATGTGATTTTGAAATTAA
ATAATCAAGAAGGTATTTCAGCCCGAGAAATGATGCAAATTATCGCAAATACAAAACCTAATTCAAAAGTTCTCGTCACC
ATTCTACGATTAGGCAAAATCTTACAAATTCCAGTTGTTATTGAAGAATTTCCAGTAAATTAA

Upstream 100 bases:

>100_bases
GAATTTAACTAAACTTGCTGATGCACCATTATGGCAACTCAATGAATTAGAACAAATCGGTGACGATATAAAATTAACTT
ACACACCGAAAGGAGTCTAA

Downstream 100 bases:

>100_bases
AAATAGCGGTCTATTTTGACCGCTGTTTTCATTATATTTAATACTTTCTTTTCAATTTGAAAATTTATTTGTTCTAACCC
CTTTTCTGACATTTCGGGCA

Product: protease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 340; Mature: 340

Protein sequence:

>340_residues
MLKKLFHSALWGLAAAGVILFAVPRLNNSNIFTSDDIISFKNAVRIASPAVVNVYNRSFSSASINDNDQLQVNNLGSGVI
MSKDGYILTNKHLIQNADQIVVALQNGNIFEASLVGSDDLTDLAVLKIRADNLSTIPQNSARQAHVGDVVLAIGNPYNLG
QSVSQGIISAIGRNAVGDSVGRQNFIQTDASINRGNSGGALINSAGELVGISTLSIGKTANEIAEGLNFAIPIDIANDVL
RKIMRDGRVIRGYFGVQSDISSSSEEGIVITDVSPNSPAAKSGIQVGDVILKLNNQEGISAREMMQIIANTKPNSKVLVT
ILRLGKILQIPVVIEEFPVN

Sequences:

>Translated_340_residues
MLKKLFHSALWGLAAAGVILFAVPRLNNSNIFTSDDIISFKNAVRIASPAVVNVYNRSFSSASINDNDQLQVNNLGSGVI
MSKDGYILTNKHLIQNADQIVVALQNGNIFEASLVGSDDLTDLAVLKIRADNLSTIPQNSARQAHVGDVVLAIGNPYNLG
QSVSQGIISAIGRNAVGDSVGRQNFIQTDASINRGNSGGALINSAGELVGISTLSIGKTANEIAEGLNFAIPIDIANDVL
RKIMRDGRVIRGYFGVQSDISSSSEEGIVITDVSPNSPAAKSGIQVGDVILKLNNQEGISAREMMQIIANTKPNSKVLVT
ILRLGKILQIPVVIEEFPVN
>Mature_340_residues
MLKKLFHSALWGLAAAGVILFAVPRLNNSNIFTSDDIISFKNAVRIASPAVVNVYNRSFSSASINDNDQLQVNNLGSGVI
MSKDGYILTNKHLIQNADQIVVALQNGNIFEASLVGSDDLTDLAVLKIRADNLSTIPQNSARQAHVGDVVLAIGNPYNLG
QSVSQGIISAIGRNAVGDSVGRQNFIQTDASINRGNSGGALINSAGELVGISTLSIGKTANEIAEGLNFAIPIDIANDVL
RKIMRDGRVIRGYFGVQSDISSSSEEGIVITDVSPNSPAAKSGIQVGDVILKLNNQEGISAREMMQIIANTKPNSKVLVT
ILRLGKILQIPVVIEEFPVN

Specific function: Unknown

COG id: COG0265

COG function: function code O; Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain

Gene ontology:

Cell location: Periplasm (Potential)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PDZ (DHR) domain

Homologues:

Organism=Homo sapiens, GI4506141, Length=293, Percent_Identity=33.1058020477816, Blast_Score=129, Evalue=3e-30,
Organism=Homo sapiens, GI22129776, Length=268, Percent_Identity=32.4626865671642, Blast_Score=125, Evalue=5e-29,
Organism=Homo sapiens, GI7019477, Length=288, Percent_Identity=30.2083333333333, Blast_Score=115, Evalue=6e-26,
Organism=Homo sapiens, GI24308541, Length=246, Percent_Identity=32.1138211382114, Blast_Score=107, Evalue=2e-23,
Organism=Escherichia coli, GI1789630, Length=356, Percent_Identity=51.4044943820225, Blast_Score=328, Evalue=3e-91,
Organism=Escherichia coli, GI1789629, Length=290, Percent_Identity=38.6206896551724, Blast_Score=190, Evalue=1e-49,
Organism=Escherichia coli, GI1786356, Length=274, Percent_Identity=39.4160583941606, Blast_Score=175, Evalue=4e-45,
Organism=Drosophila melanogaster, GI24646839, Length=291, Percent_Identity=29.553264604811, Blast_Score=121, Evalue=8e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): DEGS_HAEIN (P44947)

Other databases:

- EMBL:   L42023
- PIR:   I64103
- RefSeq:   NP_439105.1
- ProteinModelPortal:   P44947
- SMR:   P44947
- MEROPS:   S01.275
- GeneID:   949947
- GenomeReviews:   L42023_GR
- KEGG:   hin:HI0945
- NMPDR:   fig|71421.1.peg.911
- TIGR:   HI_0945
- HOGENOM:   HBG585708
- OMA:   PARSIIE
- ProtClustDB:   CLSK870232
- BioCyc:   HINF71421:HI_0945-MONOMER
- GO:   GO:0006508
- InterPro:   IPR001478
- InterPro:   IPR009003
- InterPro:   IPR011783
- InterPro:   IPR001254
- InterPro:   IPR001940
- PRINTS:   PR00834
- SMART:   SM00228
- TIGRFAMs:   TIGR02038

Pfam domain/function: PF00595 PDZ; PF00089 Trypsin; SSF50156 PDZ; SSF50494 Pept_Ser_Cys

EC number: 3.4.21.-

Molecular weight: Translated: 36040; Mature: 36040

Theoretical pI: Translated: 6.29; Mature: 6.29

Prosite motif: PS50106 PDZ

Important sites: ACT_SITE 92-92 ACT_SITE 122-122 ACT_SITE 197-197

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLKKLFHSALWGLAAAGVILFAVPRLNNSNIFTSDDIISFKNAVRIASPAVVNVYNRSFS
CHHHHHHHHHHHHHHHCCCEEEECCCCCCCEECCCCHHHHHHHHEECCCEEEEEECCCCC
SASINDNDQLQVNNLGSGVIMSKDGYILTNKHLIQNADQIVVALQNGNIFEASLVGSDDL
CCCCCCCCCEEEECCCCEEEEECCCEEEECCHHHCCCCEEEEEEECCCEEEEEECCCCCC
TDLAVLKIRADNLSTIPQNSARQAHVGDVVLAIGNPYNLGQSVSQGIISAIGRNAVGDSV
CCEEEEEEECCCCCCCCCCCCCCEECCEEEEEECCCCCCHHHHHHHHHHHHCCCCCCCHH
GRQNFIQTDASINRGNSGGALINSAGELVGISTLSIGKTANEIAEGLNFAIPIDIANDVL
CCCHHEECCCCCCCCCCCCEEEECCCCEEEEEEEECCCCHHHHHHCCCEEEEECHHHHHH
RKIMRDGRVIRGYFGVQSDISSSSEEGIVITDVSPNSPAAKSGIQVGDVILKLNNQEGIS
HHHHHCCCEEEEEECCCCCCCCCCCCCEEEEECCCCCCCHHCCCEEEEEEEEECCCCCCC
AREMMQIIANTKPNSKVLVTILRLGKILQIPVVIEEFPVN
HHHHHHHHHCCCCCCHHHHEEHHHCCEEECCEEEECCCCC
>Mature Secondary Structure
MLKKLFHSALWGLAAAGVILFAVPRLNNSNIFTSDDIISFKNAVRIASPAVVNVYNRSFS
CHHHHHHHHHHHHHHHCCCEEEECCCCCCCEECCCCHHHHHHHHEECCCEEEEEECCCCC
SASINDNDQLQVNNLGSGVIMSKDGYILTNKHLIQNADQIVVALQNGNIFEASLVGSDDL
CCCCCCCCCEEEECCCCEEEEECCCEEEECCHHHCCCCEEEEEEECCCEEEEEECCCCCC
TDLAVLKIRADNLSTIPQNSARQAHVGDVVLAIGNPYNLGQSVSQGIISAIGRNAVGDSV
CCEEEEEEECCCCCCCCCCCCCCEECCEEEEEECCCCCCHHHHHHHHHHHHCCCCCCCHH
GRQNFIQTDASINRGNSGGALINSAGELVGISTLSIGKTANEIAEGLNFAIPIDIANDVL
CCCHHEECCCCCCCCCCCCEEEECCCCEEEEEEEECCCCHHHHHHCCCEEEEECHHHHHH
RKIMRDGRVIRGYFGVQSDISSSSEEGIVITDVSPNSPAAKSGIQVGDVILKLNNQEGIS
HHHHHCCCEEEEEECCCCCCCCCCCCCEEEEECCCCCCCHHCCCEEEEEEEEECCCCCCC
AREMMQIIANTKPNSKVLVTILRLGKILQIPVVIEEFPVN
HHHHHHHHHCCCCCCHHHHEEHHHCCEEECCEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases); Serine endopeptidases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800