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The map label for this gene is atoA

Identifier: 16272714

GI number: 16272714

Start: 836026

End: 836697

Strand: Reverse

Name: atoA

Synonym: HI0773

Alternate gene names: 16272714

Gene position: 836697-836026 (Counterclockwise)

Preceding gene: 16272715

Following gene: 16272713

Centisome position: 45.72

GC content: 38.69

Gene sequence:

>672_bases
ATGAATGCAAAAGAATTAATCGCTCGCCGAATTGCGATGGAATTACATGATGGAGATATTGTTAATCTCGGTATTGGTTT
ACCAACACAGGTTGTTAATTATTTACCTGATAATGTCAATATTACACTTCAATCAGAAAATGGCTTTCTTGGTTTAACTG
CATTTGACCCAGAAAATGCTAATTCAAACTTAGTAAATGCTGGTGGTCAGCCTTGTGGAATTAAAAAAGGCGGCTCTACT
TTTGATAGTGCTTTTTCTTTCGCTTTAATTCGTGGCGGTCATGTTGATGCCTGTGTGCTAGGTGGACTTGAAGTTGATCA
AGAAGCAAATCTCGCTAACTGGATGGTGCCTGGCAAAATGGTACCAGGAATGGGCGGAGCAATGGACTTAGTGACTGGTG
CAAAAAAAGTGATTATTGGCATGGAACATTGTGCCAAGTCAGGTTCCTCAAAAATTCTAAAGAAATGTACATTACCGCTC
ACAGCAAGTAAAAAAGTTGCCATGGTGGTTACCGAATTGGCAGTATTTAACTTCATTGAAGGCAGATTAGTTCTAAAAGA
ACATGCTCCTCATGTGGATTTAGAAACAATTAAAGCCAAAACAGAAGCCGATTTCATTGTTGCCGATGATTTCAAAGAAA
TGCAAATCAGCCAGAAAGGACTTGAATTATGA

Upstream 100 bases:

>100_bases
GTTGATAATCTACTAGAGGTCGGTCAGTTACCCCCAGATGAAGTCATCACGCCAGCCGCATTAATTGATTACATTGTTTG
TTCAGAATAAGGAGAACGCC

Downstream 100 bases:

>100_bases
TTAGTCGCGTTTCTCGTTTTATGACGACATTCGTCAGTAAATACCTGCCAGACCCACTTATTTTTGCCGTGTTACTCACC
TTTGTCACATTCATTTGTGC

Product: acetate CoA-transferase subunit beta

Products: NA

Alternate protein names: Acetyl-CoA:acetoacetate-CoA transferase subunit beta

Number of amino acids: Translated: 223; Mature: 223

Protein sequence:

>223_residues
MNAKELIARRIAMELHDGDIVNLGIGLPTQVVNYLPDNVNITLQSENGFLGLTAFDPENANSNLVNAGGQPCGIKKGGST
FDSAFSFALIRGGHVDACVLGGLEVDQEANLANWMVPGKMVPGMGGAMDLVTGAKKVIIGMEHCAKSGSSKILKKCTLPL
TASKKVAMVVTELAVFNFIEGRLVLKEHAPHVDLETIKAKTEADFIVADDFKEMQISQKGLEL

Sequences:

>Translated_223_residues
MNAKELIARRIAMELHDGDIVNLGIGLPTQVVNYLPDNVNITLQSENGFLGLTAFDPENANSNLVNAGGQPCGIKKGGST
FDSAFSFALIRGGHVDACVLGGLEVDQEANLANWMVPGKMVPGMGGAMDLVTGAKKVIIGMEHCAKSGSSKILKKCTLPL
TASKKVAMVVTELAVFNFIEGRLVLKEHAPHVDLETIKAKTEADFIVADDFKEMQISQKGLEL
>Mature_223_residues
MNAKELIARRIAMELHDGDIVNLGIGLPTQVVNYLPDNVNITLQSENGFLGLTAFDPENANSNLVNAGGQPCGIKKGGST
FDSAFSFALIRGGHVDACVLGGLEVDQEANLANWMVPGKMVPGMGGAMDLVTGAKKVIIGMEHCAKSGSSKILKKCTLPL
TASKKVAMVVTELAVFNFIEGRLVLKEHAPHVDLETIKAKTEADFIVADDFKEMQISQKGLEL

Specific function: SHORT-CHAIN FATTY ACIDS METABOLISM. [C]

COG id: COG2057

COG function: function code I; Acyl CoA:acetate/3-ketoacid CoA transferase, beta subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 3-oxoacid CoA-transferase subunit B family

Homologues:

Organism=Homo sapiens, GI4557817, Length=217, Percent_Identity=45.6221198156682, Blast_Score=186, Evalue=2e-47,
Organism=Homo sapiens, GI11545841, Length=217, Percent_Identity=42.8571428571429, Blast_Score=180, Evalue=1e-45,
Organism=Escherichia coli, GI1788552, Length=220, Percent_Identity=68.1818181818182, Blast_Score=305, Evalue=1e-84,
Organism=Caenorhabditis elegans, GI17531517, Length=215, Percent_Identity=43.2558139534884, Blast_Score=177, Evalue=3e-45,
Organism=Drosophila melanogaster, GI21358325, Length=214, Percent_Identity=49.5327102803738, Blast_Score=197, Evalue=6e-51,
Organism=Drosophila melanogaster, GI24655794, Length=214, Percent_Identity=49.5327102803738, Blast_Score=197, Evalue=6e-51,

Paralogues:

None

Copy number: 369 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): ATOA_HAEIN (P44874)

Other databases:

- EMBL:   L42023
- PIR:   G64158
- RefSeq:   NP_438932.1
- ProteinModelPortal:   P44874
- SMR:   P44874
- GeneID:   949789
- GenomeReviews:   L42023_GR
- KEGG:   hin:HI0773
- NMPDR:   fig|71421.1.peg.741
- TIGR:   HI_0773
- HOGENOM:   HBG353770
- OMA:   PENANSN
- ProtClustDB:   CLSK891766
- BioCyc:   HINF71421:HI_0773-MONOMER
- BRENDA:   2.8.3.8
- InterPro:   IPR012791
- InterPro:   IPR004165
- InterPro:   IPR004164
- PANTHER:   PTHR13707
- SMART:   SM00882
- TIGRFAMs:   TIGR02428

Pfam domain/function: PF01144 CoA_trans

EC number: =2.8.3.8

Molecular weight: Translated: 23750; Mature: 23750

Theoretical pI: Translated: 5.64; Mature: 5.64

Prosite motif: PS01274 COA_TRANSF_2

Important sites: ACT_SITE 46-46

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
5.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNAKELIARRIAMELHDGDIVNLGIGLPTQVVNYLPDNVNITLQSENGFLGLTAFDPENA
CCHHHHHHHHHHHHCCCCCEEEECCCCHHHHHHHCCCCCEEEEECCCCEEEEEEECCCCC
NSNLVNAGGQPCGIKKGGSTFDSAFSFALIRGGHVDACVLGGLEVDQEANLANWMVPGKM
CCCEEECCCCCCCCCCCCCCHHHHHEEEEEECCCCCEEEECCCCCCCCCCCCCEECCCCC
VPGMGGAMDLVTGAKKVIIGMEHCAKSGSSKILKKCTLPLTASKKVAMVVTELAVFNFIE
CCCCCCHHHHHHCCHHEEEEHHHHHCCCCHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHC
GRLVLKEHAPHVDLETIKAKTEADFIVADDFKEMQISQKGLEL
CEEEEECCCCCCCHHHHHCCCCCCEEEECCHHHHHHHHCCCCC
>Mature Secondary Structure
MNAKELIARRIAMELHDGDIVNLGIGLPTQVVNYLPDNVNITLQSENGFLGLTAFDPENA
CCHHHHHHHHHHHHCCCCCEEEECCCCHHHHHHHCCCCCEEEEECCCCEEEEEEECCCCC
NSNLVNAGGQPCGIKKGGSTFDSAFSFALIRGGHVDACVLGGLEVDQEANLANWMVPGKM
CCCEEECCCCCCCCCCCCCCHHHHHEEEEEECCCCCEEEECCCCCCCCCCCCCEECCCCC
VPGMGGAMDLVTGAKKVIIGMEHCAKSGSSKILKKCTLPLTASKKVAMVVTELAVFNFIE
CCCCCCHHHHHHCCHHEEEEHHHHHCCCCHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHC
GRLVLKEHAPHVDLETIKAKTEADFIVADDFKEMQISQKGLEL
CEEEEECCCCCCCHHHHHCCCCCCEEEECCHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800