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The map label for this gene is atoD

Identifier: 16272715

GI number: 16272715

Start: 836708

End: 837361

Strand: Reverse

Name: atoD

Synonym: HI0774

Alternate gene names: 16272715

Gene position: 837361-836708 (Counterclockwise)

Preceding gene: 16272746

Following gene: 16272714

Centisome position: 45.75

GC content: 40.06

Gene sequence:

>654_bases
ATGACACAAAAACATCTTAAGCTTAATAATCTAAATCAACACCTACATGATGGTATGAGCATCATGTTTGGTGGATTTAT
GGGTATCGGCACTCCAGCCAAACTTGTCCAACAAATCTTAGATTCTGGCGTAAAGGATCTCACACTCATAGGCAATGACA
CAGCCTTTATTGACACTGGCGTAGGCCCTTTAATTGTAAATAATCGAGTCAAACGTTTAATTACCTCCCATATTGGTACA
AATCCAGAAACTGGCAAAAAAATGATTGCTGGTGAAATAGATGTAGAACTCGTTCCACAGGGAACCTTAGCTGAACGGAT
TCGTGCAGGTGGCGCCGGATTAGGTGGTATTTTAACACCAACGGGTGTCGGCACTGTTGTTGAAGAAGGAAAACAAAAAA
TTCAAATTGATGGCAGAGAATATTTGCTTGAACTCCCACTAAAAGCTGATATTGCCATTATCCATGCTCAAAAAGGTGAC
ATGAATGGCAATTTAGCTTATGAATTATCTGCTAGGAACTTTAATCCACTAGTTGCTTTAGCAGCCAAAACTGTCATTGC
CCAAGTTGATAATCTACTAGAGGTCGGTCAGTTACCCCCAGATGAAGTCATCACGCCAGCCGCATTAATTGATTACATTG
TTTGTTCAGAATAA

Upstream 100 bases:

>100_bases
ATTGCCTATCAAGGATCATCGCAAGAAACATATCCATTTGAAATATAAGATACTTATTTGTTGATATTCTTTCTTTTAAT
CTCGTTATTAGGAGGTCTCT

Downstream 100 bases:

>100_bases
GGAGAACGCCATGAATGCAAAAGAATTAATCGCTCGCCGAATTGCGATGGAATTACATGATGGAGATATTGTTAATCTCG
GTATTGGTTTACCAACACAG

Product: acetyl-CoA:acetoacetyl-CoA transferase subunit alpha

Products: NA

Alternate protein names: Acetyl-CoA:acetoacetate-CoA transferase subunit alpha

Number of amino acids: Translated: 217; Mature: 216

Protein sequence:

>217_residues
MTQKHLKLNNLNQHLHDGMSIMFGGFMGIGTPAKLVQQILDSGVKDLTLIGNDTAFIDTGVGPLIVNNRVKRLITSHIGT
NPETGKKMIAGEIDVELVPQGTLAERIRAGGAGLGGILTPTGVGTVVEEGKQKIQIDGREYLLELPLKADIAIIHAQKGD
MNGNLAYELSARNFNPLVALAAKTVIAQVDNLLEVGQLPPDEVITPAALIDYIVCSE

Sequences:

>Translated_217_residues
MTQKHLKLNNLNQHLHDGMSIMFGGFMGIGTPAKLVQQILDSGVKDLTLIGNDTAFIDTGVGPLIVNNRVKRLITSHIGT
NPETGKKMIAGEIDVELVPQGTLAERIRAGGAGLGGILTPTGVGTVVEEGKQKIQIDGREYLLELPLKADIAIIHAQKGD
MNGNLAYELSARNFNPLVALAAKTVIAQVDNLLEVGQLPPDEVITPAALIDYIVCSE
>Mature_216_residues
TQKHLKLNNLNQHLHDGMSIMFGGFMGIGTPAKLVQQILDSGVKDLTLIGNDTAFIDTGVGPLIVNNRVKRLITSHIGTN
PETGKKMIAGEIDVELVPQGTLAERIRAGGAGLGGILTPTGVGTVVEEGKQKIQIDGREYLLELPLKADIAIIHAQKGDM
NGNLAYELSARNFNPLVALAAKTVIAQVDNLLEVGQLPPDEVITPAALIDYIVCSE

Specific function: SHORT-CHAIN FATTY ACIDS METABOLISM. [C]

COG id: COG1788

COG function: function code I; Acyl CoA:acetate/3-ketoacid CoA transferase, alpha subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 3-oxoacid CoA-transferase subunit A family

Homologues:

Organism=Homo sapiens, GI4557817, Length=219, Percent_Identity=35.6164383561644, Blast_Score=157, Evalue=5e-39,
Organism=Homo sapiens, GI11545841, Length=220, Percent_Identity=36.3636363636364, Blast_Score=149, Evalue=3e-36,
Organism=Escherichia coli, GI1788551, Length=217, Percent_Identity=63.1336405529954, Blast_Score=294, Evalue=3e-81,
Organism=Escherichia coli, GI1787985, Length=176, Percent_Identity=27.8409090909091, Blast_Score=67, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17531517, Length=222, Percent_Identity=33.3333333333333, Blast_Score=140, Evalue=7e-34,
Organism=Drosophila melanogaster, GI21358325, Length=217, Percent_Identity=39.63133640553, Blast_Score=161, Evalue=3e-40,
Organism=Drosophila melanogaster, GI24655794, Length=217, Percent_Identity=39.63133640553, Blast_Score=160, Evalue=4e-40,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ATOD_HAEIN (P44875)

Other databases:

- EMBL:   L42023
- PIR:   B64092
- RefSeq:   NP_438933.1
- ProteinModelPortal:   P44875
- SMR:   P44875
- GeneID:   949792
- GenomeReviews:   L42023_GR
- KEGG:   hin:HI0774
- NMPDR:   fig|71421.1.peg.742
- TIGR:   HI_0774
- HOGENOM:   HBG288750
- OMA:   YLLELPI
- ProtClustDB:   PRK09920
- BioCyc:   HINF71421:HI_0774-MONOMER
- BRENDA:   2.8.3.8
- InterPro:   IPR012792
- InterPro:   IPR004165
- InterPro:   IPR004163
- PANTHER:   PTHR13707
- SMART:   SM00882
- TIGRFAMs:   TIGR02429

Pfam domain/function: PF01144 CoA_trans

EC number: =2.8.3.8

Molecular weight: Translated: 23090; Mature: 22959

Theoretical pI: Translated: 5.27; Mature: 5.27

Prosite motif: PS01273 COA_TRANSF_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTQKHLKLNNLNQHLHDGMSIMFGGFMGIGTPAKLVQQILDSGVKDLTLIGNDTAFIDTG
CCCCCCCHHHHHHHHHCCHHHHHCCCCCCCCHHHHHHHHHHCCCCEEEEECCCCEEEECC
VGPLIVNNRVKRLITSHIGTNPETGKKMIAGEIDVELVPQGTLAERIRAGGAGLGGILTP
CCCEEHHHHHHHHHHHHCCCCCCCCCEEEECCCCEEEECCCHHHHHHHCCCCCCCCCCCC
TGVGTVVEEGKQKIQIDGREYLLELPLKADIAIIHAQKGDMNGNLAYELSARNFNPLVAL
CCCHHHHHCCCCEEEECCCEEEEECCCCCCEEEEEECCCCCCCCEEEEEECCCCCHHHHH
AAKTVIAQVDNLLEVGQLPPDEVITPAALIDYIVCSE
HHHHHHHHHHHHHHHCCCCCHHHCCHHHHHHHHHCCC
>Mature Secondary Structure 
TQKHLKLNNLNQHLHDGMSIMFGGFMGIGTPAKLVQQILDSGVKDLTLIGNDTAFIDTG
CCCCCCHHHHHHHHHCCHHHHHCCCCCCCCHHHHHHHHHHCCCCEEEEECCCCEEEECC
VGPLIVNNRVKRLITSHIGTNPETGKKMIAGEIDVELVPQGTLAERIRAGGAGLGGILTP
CCCEEHHHHHHHHHHHHCCCCCCCCCEEEECCCCEEEECCCHHHHHHHCCCCCCCCCCCC
TGVGTVVEEGKQKIQIDGREYLLELPLKADIAIIHAQKGDMNGNLAYELSARNFNPLVAL
CCCHHHHHCCCCEEEECCCEEEEECCCCCCEEEEEECCCCCCCCEEEEEECCCCCHHHHH
AAKTVIAQVDNLLEVGQLPPDEVITPAALIDYIVCSE
HHHHHHHHHHHHHHHCCCCCHHHCCHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800