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The map label for this gene is trkA

Identifier: 16272568

GI number: 16272568

Start: 665535

End: 666911

Strand: Direct

Name: trkA

Synonym: HI0625

Alternate gene names: 16272568

Gene position: 665535-666911 (Clockwise)

Preceding gene: 16272567

Following gene: 16272569

Centisome position: 36.37

GC content: 38.85

Gene sequence:

>1377_bases
ATGAAAATTATCATTTTGGGTGCAGGTCAGGTAGGAACGACGCTTGCAGAAAACTTAGTCAGTGAAGATAACGATATTAC
CTTAGTGGATAATGAATCTCCTCAGTTACAAACATTGCAAGAAAAGCACGATTTGCGTGTGGTACAAGGCTCTCCATCAT
CTCCAAAAGTGCTTCGTGACGCAGGCGCGGCAGATGCCGATTTAATGGTTGCTGTGACAGCCTCTGATGAAATCAATATG
GTCGCCTGCCAAATGGGCTATACATTATTTAATACGCCAACGCGAATTGCACGTATCCGTAATTCAGAATATTTACGTGA
AAAAGACAAGTTGTTCAACAATGAAAATATTCCTATTGATCATTTAATTTCGCCTGAAAATCTTGTAACTGATGAAATTA
CACGTTTAATTGCTTATCCAGGCGCATTACAAGTTGCCCATTTTGCCAATAATCGTATTAGTATTGTTGTAGTGAAAGCT
TATTATGGGGGGGCTTTGGTTGGATATGCACTTTCCGCATTTCGCGAACATATGCCACATATTGATTGTCGCATTATGTC
TATTTTACGTAATGGCAAACCGATTCGTCCACAAGGCTCAACCATTGTAGAAGCTGGCGATGAAATCACGTTTATTTGCG
CTACTGAACATATTAAGGCGATAATGGGAGAGTTACAACGTTTGGAGAAACCTTATAAGCGAGTAATGATTGTTGGTGGA
GGAAATGTTGCTTTTGGCGTAGCAAAACGTTTGGAAAATTCTTGTACTGTAAAGCTTATTGAACGAGATTCAAACAGAGC
GCAAGCCTTAGCAGAAAAGTTGCCAAAAACGTTAGTATTTAATGGAGATGCCTCAGACCAAAACTTGCTTTTTGAAGAAC
ATATTGAAAGTGTGGATGTATTTCTTTCATTAAGTAGCGACGATGAAGCGAATATTATGTCAGCTTTGTTAGCCAAGCGT
TTAGGTGCGAAAAAAGCAATGGTACTGATTCAACGGATTGCTTATATTAATCTTATTCAGGGAGGCACGATTGATATTGC
GGTTTCTCCACAACAAGTAACGATTTCTGCTTTGTTAGGTCACGTGCGTAAAGGCGATGTAAAAAATGTGGCAACATTAC
GACATGGCATTGCCGAAGCCATTGAAATTGTTGCACACGGTAATGTGAATACTTCAAATATAGTAGGGCGAAAAATTGGT
GAGTTGCGTTTGCCGATGGGAATCATTATTGGTGCTTTATTACGAGGGAATGATGTAATTATTGCTCGTCGTCAAGTGAT
TATTGAAGAAGGCGATCATATAGTGATTTATTTAAGTGATAAGAAAAATGTGCCAGAAATTGAGAAATTATTCCAACCAA
GCGCATTCTTTATTTAG

Upstream 100 bases:

>100_bases
TAAAAGTGCGGTGGGTTTTCAATTTATTCCGCAACCAAATAGTGGCGATGGGTTCTATTATGCGAAATTGCTTAAACGAG
CATCATAAAGGAGGGTGATA

Downstream 100 bases:

>100_bases
TTTTTTTACTTTTCAGAGTGATTTATTATAATAGTCGCTCTTTTTATGTAATTTTTGAAGGGGAACATTATTATGAATTT
TATTAAAGAATTTCGCGAAT

Product: potassium transporter peripheral membrane component

Products: NA

Alternate protein names: K(+)-uptake protein trkA

Number of amino acids: Translated: 458; Mature: 458

Protein sequence:

>458_residues
MKIIILGAGQVGTTLAENLVSEDNDITLVDNESPQLQTLQEKHDLRVVQGSPSSPKVLRDAGAADADLMVAVTASDEINM
VACQMGYTLFNTPTRIARIRNSEYLREKDKLFNNENIPIDHLISPENLVTDEITRLIAYPGALQVAHFANNRISIVVVKA
YYGGALVGYALSAFREHMPHIDCRIMSILRNGKPIRPQGSTIVEAGDEITFICATEHIKAIMGELQRLEKPYKRVMIVGG
GNVAFGVAKRLENSCTVKLIERDSNRAQALAEKLPKTLVFNGDASDQNLLFEEHIESVDVFLSLSSDDEANIMSALLAKR
LGAKKAMVLIQRIAYINLIQGGTIDIAVSPQQVTISALLGHVRKGDVKNVATLRHGIAEAIEIVAHGNVNTSNIVGRKIG
ELRLPMGIIIGALLRGNDVIIARRQVIIEEGDHIVIYLSDKKNVPEIEKLFQPSAFFI

Sequences:

>Translated_458_residues
MKIIILGAGQVGTTLAENLVSEDNDITLVDNESPQLQTLQEKHDLRVVQGSPSSPKVLRDAGAADADLMVAVTASDEINM
VACQMGYTLFNTPTRIARIRNSEYLREKDKLFNNENIPIDHLISPENLVTDEITRLIAYPGALQVAHFANNRISIVVVKA
YYGGALVGYALSAFREHMPHIDCRIMSILRNGKPIRPQGSTIVEAGDEITFICATEHIKAIMGELQRLEKPYKRVMIVGG
GNVAFGVAKRLENSCTVKLIERDSNRAQALAEKLPKTLVFNGDASDQNLLFEEHIESVDVFLSLSSDDEANIMSALLAKR
LGAKKAMVLIQRIAYINLIQGGTIDIAVSPQQVTISALLGHVRKGDVKNVATLRHGIAEAIEIVAHGNVNTSNIVGRKIG
ELRLPMGIIIGALLRGNDVIIARRQVIIEEGDHIVIYLSDKKNVPEIEKLFQPSAFFI
>Mature_458_residues
MKIIILGAGQVGTTLAENLVSEDNDITLVDNESPQLQTLQEKHDLRVVQGSPSSPKVLRDAGAADADLMVAVTASDEINM
VACQMGYTLFNTPTRIARIRNSEYLREKDKLFNNENIPIDHLISPENLVTDEITRLIAYPGALQVAHFANNRISIVVVKA
YYGGALVGYALSAFREHMPHIDCRIMSILRNGKPIRPQGSTIVEAGDEITFICATEHIKAIMGELQRLEKPYKRVMIVGG
GNVAFGVAKRLENSCTVKLIERDSNRAQALAEKLPKTLVFNGDASDQNLLFEEHIESVDVFLSLSSDDEANIMSALLAKR
LGAKKAMVLIQRIAYINLIQGGTIDIAVSPQQVTISALLGHVRKGDVKNVATLRHGIAEAIEIVAHGNVNTSNIVGRKIG
ELRLPMGIIIGALLRGNDVIIARRQVIIEEGDHIVIYLSDKKNVPEIEKLFQPSAFFI

Specific function: Part of a potassium transport system

COG id: COG0569

COG function: function code P; K+ transport systems, NAD-binding component

Gene ontology:

Cell location: Peripherally Bound To The Inner Side Of The Inner Membrane Via The Trkg And Trkh Proteins [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 RCK N-terminal domains

Homologues:

Organism=Escherichia coli, GI1789685, Length=458, Percent_Identity=65.938864628821, Blast_Score=642, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): TRKA_HAEIN (P71354)

Other databases:

- EMBL:   L42023
- RefSeq:   NP_438785.1
- ProteinModelPortal:   P71354
- SMR:   P71354
- GeneID:   949682
- GenomeReviews:   L42023_GR
- KEGG:   hin:HI0625
- NMPDR:   fig|71421.1.peg.595
- TIGR:   HI_0625
- HOGENOM:   HBG697234
- OMA:   HTPTKIA
- ProtClustDB:   PRK09496
- BioCyc:   HINF71421:HI_0625-MONOMER
- GO:   GO:0005488
- InterPro:   IPR006036
- InterPro:   IPR016040
- InterPro:   IPR006037
- InterPro:   IPR003148
- Gene3D:   G3DSA:3.40.50.720
- PRINTS:   PR00335

Pfam domain/function: PF02080 TrkA_C; PF02254 TrkA_N

EC number: NA

Molecular weight: Translated: 50175; Mature: 50175

Theoretical pI: Translated: 6.59; Mature: 6.59

Prosite motif: PS51202 RCK_C; PS51201 RCK_N

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIIILGAGQVGTTLAENLVSEDNDITLVDNESPQLQTLQEKHDLRVVQGSPSSPKVLRD
CEEEEEECCCHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHCCEEEEECCCCCCHHHHH
AGAADADLMVAVTASDEINMVACQMGYTLFNTPTRIARIRNSEYLREKDKLFNNENIPID
CCCCCCCEEEEEECCCCCEEEEEECCCEEECCCHHHHHHCCHHHHHHHHHHCCCCCCCHH
HLISPENLVTDEITRLIAYPGALQVAHFANNRISIVVVKAYYGGALVGYALSAFREHMPH
HCCCCCHHHHHHHHHHHHCCCCEEEEEECCCEEEEEEEEECCCCHHHHHHHHHHHHHCCC
IDCRIMSILRNGKPIRPQGSTIVEAGDEITFICATEHIKAIMGELQRLEKPYKRVMIVGG
HHHHHHHHHHCCCCCCCCCCEEEECCCCEEEEEEHHHHHHHHHHHHHHCCHHHEEEEECC
GNVAFGVAKRLENSCTVKLIERDSNRAQALAEKLPKTLVFNGDASDQNLLFEEHIESVDV
CCCHHHHHHHCCCCCEEEEEECCCCHHHHHHHHCCCEEEECCCCCCCCCHHHHHHCCEEE
FLSLSSDDEANIMSALLAKRLGAKKAMVLIQRIAYINLIQGGTIDIAVSPQQVTISALLG
EEEECCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHEEECCCEEEEEECCCCEEHHHHHH
HVRKGDVKNVATLRHGIAEAIEIVAHGNVNTSNIVGRKIGELRLPMGIIIGALLRGNDVI
HHCCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHCCCEEE
IARRQVIIEEGDHIVIYLSDKKNVPEIEKLFQPSAFFI
EEEEEEEEECCCEEEEEECCCCCCCHHHHHCCCCCCCC
>Mature Secondary Structure
MKIIILGAGQVGTTLAENLVSEDNDITLVDNESPQLQTLQEKHDLRVVQGSPSSPKVLRD
CEEEEEECCCHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHCCEEEEECCCCCCHHHHH
AGAADADLMVAVTASDEINMVACQMGYTLFNTPTRIARIRNSEYLREKDKLFNNENIPID
CCCCCCCEEEEEECCCCCEEEEEECCCEEECCCHHHHHHCCHHHHHHHHHHCCCCCCCHH
HLISPENLVTDEITRLIAYPGALQVAHFANNRISIVVVKAYYGGALVGYALSAFREHMPH
HCCCCCHHHHHHHHHHHHCCCCEEEEEECCCEEEEEEEEECCCCHHHHHHHHHHHHHCCC
IDCRIMSILRNGKPIRPQGSTIVEAGDEITFICATEHIKAIMGELQRLEKPYKRVMIVGG
HHHHHHHHHHCCCCCCCCCCEEEECCCCEEEEEEHHHHHHHHHHHHHHCCHHHEEEEECC
GNVAFGVAKRLENSCTVKLIERDSNRAQALAEKLPKTLVFNGDASDQNLLFEEHIESVDV
CCCHHHHHHHCCCCCEEEEEECCCCHHHHHHHHCCCEEEECCCCCCCCCHHHHHHCCEEE
FLSLSSDDEANIMSALLAKRLGAKKAMVLIQRIAYINLIQGGTIDIAVSPQQVTISALLG
EEEECCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHEEECCCEEEEEECCCCEEHHHHHH
HVRKGDVKNVATLRHGIAEAIEIVAHGNVNTSNIVGRKIGELRLPMGIIIGALLRGNDVI
HHCCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHCCCEEE
IARRQVIIEEGDHIVIYLSDKKNVPEIEKLFQPSAFFI
EEEEEEEEECCCEEEEEECCCCCCCHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800