Click here to switch to the map view.

The map label for this gene is kdgK

Identifier: 16272024

GI number: 16272024

Start: 49848

End: 50792

Strand: Reverse

Name: kdgK

Synonym: HI0049

Alternate gene names: 16272024

Gene position: 50792-49848 (Counterclockwise)

Preceding gene: 16273630

Following gene: 16272023

Centisome position: 2.78

GC content: 35.34

Gene sequence:

>945_bases
ATGAAAAAAATAGCATTTATCGGCGAGTGTATGATTGAACTCAATGGGAAACCCTTTGCGGAAATGTGGCAAAGTTATGG
TGGAGATACCTTAAATTCTGCAACTTATCTTAGTCGAGTAAGTTCATCAAAAGAGATTCAAGTTCATTATGTCTCTGCAT
TAGGAACCGATAATTTAAGCAAGCAAATGCTTAAATATTGGCAAGCTGATGGCATCCAAACAAATTGGGTTTTACAGGAT
GAACAGCACCAACCAGGTCTTTATCTAATCCAATTAGATGCTCAAGGCGAACGCACGTTCCTTTATTGGCGTAATCAATC
TGCAGCACGTTATATGGTTCAACATCCGGATTTTGCTAAGGTTATTGCAGAACTTCAGCAAGTTGATGTGATTTATTTAA
GTGGTATTTCATTAGCAATCTTACCTAAAAATGACCGCACTTTTTTAATTGAACAATTATCTTCTTTAGCTAAAAAAGGC
ACAGAAATTGTTTTTGATAGTAATTATCGCCCAAAACTTTGGGATTCATTAGAAGAAGCACAAGATTGTTATTTGCAGCT
TTTGCCTAGTGTCAATATAGCGTTGGTGACTTTTGATGATGAACAAGCATTATGGAAAGATAAAACATCTAGGGATACTT
TAGAGCGATTACATAAAATTGGTATACCAAAAGTGATTGTGAAGTGCGGTAAGAATGGTGCTATTTTTTCAGATAGGTAT
TTATCTCAATATGGGCAAGTGATACCTGAACCTATTTTAAATGTAGTGGATACAACCTCGGCTGGTGATTCTTTTAATGC
TGGATTTCTGAACGGTTATTTACGAAATAAATCTCTCGAAATTTGTTGTCAGCAAGGCAATCGTATTGCTGGTATCGTCA
TTCAACATAAAGGTGCGATTATAGATAAAGTCGCAATTTCTCATCTTCAATCTGAATTTAATTAA

Upstream 100 bases:

>100_bases
TTATTTGTGTACGCAATTATTATGATGTTGATCGTATTTTTTCCTGAAATTGTAATTGTTCCAATGAATTGGTTATCTTG
ATTTATTAGGAAGTTACATC

Downstream 100 bases:

>100_bases
TGGAGTTTACTATGAATATTGCAGCAAACCATAACTTAGAAAATAAACTAATTATAATCACGGGGGCTGGCGGAGTGTTA
TGTTCATTTCTCGCTAAGCA

Product: 2-dehydro-3-deoxygluconokinase

Products: NA

Alternate protein names: 2-keto-3-deoxygluconokinase; 3-deoxy-2-oxo-D-gluconate kinase; KDG kinase

Number of amino acids: Translated: 314; Mature: 314

Protein sequence:

>314_residues
MKKIAFIGECMIELNGKPFAEMWQSYGGDTLNSATYLSRVSSSKEIQVHYVSALGTDNLSKQMLKYWQADGIQTNWVLQD
EQHQPGLYLIQLDAQGERTFLYWRNQSAARYMVQHPDFAKVIAELQQVDVIYLSGISLAILPKNDRTFLIEQLSSLAKKG
TEIVFDSNYRPKLWDSLEEAQDCYLQLLPSVNIALVTFDDEQALWKDKTSRDTLERLHKIGIPKVIVKCGKNGAIFSDRY
LSQYGQVIPEPILNVVDTTSAGDSFNAGFLNGYLRNKSLEICCQQGNRIAGIVIQHKGAIIDKVAISHLQSEFN

Sequences:

>Translated_314_residues
MKKIAFIGECMIELNGKPFAEMWQSYGGDTLNSATYLSRVSSSKEIQVHYVSALGTDNLSKQMLKYWQADGIQTNWVLQD
EQHQPGLYLIQLDAQGERTFLYWRNQSAARYMVQHPDFAKVIAELQQVDVIYLSGISLAILPKNDRTFLIEQLSSLAKKG
TEIVFDSNYRPKLWDSLEEAQDCYLQLLPSVNIALVTFDDEQALWKDKTSRDTLERLHKIGIPKVIVKCGKNGAIFSDRY
LSQYGQVIPEPILNVVDTTSAGDSFNAGFLNGYLRNKSLEICCQQGNRIAGIVIQHKGAIIDKVAISHLQSEFN
>Mature_314_residues
MKKIAFIGECMIELNGKPFAEMWQSYGGDTLNSATYLSRVSSSKEIQVHYVSALGTDNLSKQMLKYWQADGIQTNWVLQD
EQHQPGLYLIQLDAQGERTFLYWRNQSAARYMVQHPDFAKVIAELQQVDVIYLSGISLAILPKNDRTFLIEQLSSLAKKG
TEIVFDSNYRPKLWDSLEEAQDCYLQLLPSVNIALVTFDDEQALWKDKTSRDTLERLHKIGIPKVIVKCGKNGAIFSDRY
LSQYGQVIPEPILNVVDTTSAGDSFNAGFLNGYLRNKSLEICCQQGNRIAGIVIQHKGAIIDKVAISHLQSEFN

Specific function: Unknown

COG id: COG0524

COG function: function code G; Sugar kinases, ribokinase family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the carbohydrate kinase pfkB family

Homologues:

Organism=Escherichia coli, GI87082281, Length=309, Percent_Identity=43.6893203883495, Blast_Score=259, Evalue=2e-70,
Organism=Escherichia coli, GI87081971, Length=289, Percent_Identity=23.8754325259516, Blast_Score=81, Evalue=9e-17,
Organism=Escherichia coli, GI1789775, Length=304, Percent_Identity=26.3157894736842, Blast_Score=69, Evalue=4e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): KDGK_HAEIN (P44482)

Other databases:

- EMBL:   L42023
- PIR:   C64045
- RefSeq:   NP_438222.1
- ProteinModelPortal:   P44482
- GeneID:   950949
- GenomeReviews:   L42023_GR
- KEGG:   hin:HI0049
- NMPDR:   fig|71421.1.peg.48
- TIGR:   HI_0049
- HOGENOM:   HBG697973
- OMA:   YWQADGI
- ProtClustDB:   CLSK892352
- BioCyc:   HINF71421:HI_0049-MONOMER
- BRENDA:   2.7.1.45
- InterPro:   IPR011611
- InterPro:   IPR002173

Pfam domain/function: PF00294 PfkB

EC number: =2.7.1.45

Molecular weight: Translated: 35463; Mature: 35463

Theoretical pI: Translated: 6.25; Mature: 6.25

Prosite motif: PS00583 PFKB_KINASES_1; PS00584 PFKB_KINASES_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKIAFIGECMIELNGKPFAEMWQSYGGDTLNSATYLSRVSSSKEIQVHYVSALGTDNLS
CCCHHEEEEEEEEECCCCHHHHHHHHCCCCCCHHHHHHHHCCCCEEEEEEEEECCCCHHH
KQMLKYWQADGIQTNWVLQDEQHQPGLYLIQLDAQGERTFLYWRNQSAARYMVQHPDFAK
HHHHHHHHCCCCEEEEEEECCCCCCCEEEEEEECCCCEEEEEEECCCHHHHHHCCCCHHH
VIAELQQVDVIYLSGISLAILPKNDRTFLIEQLSSLAKKGTEIVFDSNYRPKLWDSLEEA
HHHHHHHCCEEEECCCEEEEEECCCCHHHHHHHHHHHHCCCEEEECCCCCCHHHHHHHHH
QDCYLQLLPSVNIALVTFDDEQALWKDKTSRDTLERLHKIGIPKVIVKCGKNGAIFSDRY
HHHHHHHCCCCCEEEEEECCCHHHHCCCCCHHHHHHHHHCCCCHHHHHCCCCCCEEHHHH
LSQYGQVIPEPILNVVDTTSAGDSFNAGFLNGYLRNKSLEICCQQGNRIAGIVIQHKGAI
HHHHHHHCCHHHHHHHCCCCCCCCCCCHHHHHHHCCCHHHHHHHCCCEEEEEEEECCCCH
IDKVAISHLQSEFN
HHHHHHHHHHHHCC
>Mature Secondary Structure
MKKIAFIGECMIELNGKPFAEMWQSYGGDTLNSATYLSRVSSSKEIQVHYVSALGTDNLS
CCCHHEEEEEEEEECCCCHHHHHHHHCCCCCCHHHHHHHHCCCCEEEEEEEEECCCCHHH
KQMLKYWQADGIQTNWVLQDEQHQPGLYLIQLDAQGERTFLYWRNQSAARYMVQHPDFAK
HHHHHHHHCCCCEEEEEEECCCCCCCEEEEEEECCCCEEEEEEECCCHHHHHHCCCCHHH
VIAELQQVDVIYLSGISLAILPKNDRTFLIEQLSSLAKKGTEIVFDSNYRPKLWDSLEEA
HHHHHHHCCEEEECCCEEEEEECCCCHHHHHHHHHHHHCCCEEEECCCCCCHHHHHHHHH
QDCYLQLLPSVNIALVTFDDEQALWKDKTSRDTLERLHKIGIPKVIVKCGKNGAIFSDRY
HHHHHHHCCCCCEEEEEECCCHHHHCCCCCHHHHHHHHHCCCCHHHHHCCCCCCEEHHHH
LSQYGQVIPEPILNVVDTTSAGDSFNAGFLNGYLRNKSLEICCQQGNRIAGIVIQHKGAI
HHHHHHHCCHHHHHHHCCCCCCCCCCCHHHHHHHCCCHHHHHHHCCCEEEEEEEECCCCH
IDKVAISHLQSEFN
HHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800