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The map label for this gene is glsA [H]

Identifier: 91790205

GI number: 91790205

Start: 4612224

End: 4613117

Strand: Reverse

Name: glsA [H]

Synonym: Bpro_4370

Alternate gene names: 91790205

Gene position: 4613117-4612224 (Counterclockwise)

Preceding gene: 91790206

Following gene: 91790203

Centisome position: 88.71

GC content: 56.82

Gene sequence:

>894_bases
ATGCCAATTGACGATGCCGACGGGCTCCTGGCCCACATTGCCGCGCAAGTGCGGCCCCTTCTGCCACAGGGCCAGTTGCC
CCAATACATTCCACAACTGGGAAGGGTGGACAAGATGCAGTTCGGCATGGCGCTGCTCATGCTGGACGGCCGGGAAGCAT
TCGTCGGAGACGCTGATGTGCCGTTTTCGATTCAAAGTATTTCCAAATTGTTCGCCCTCATGCTGGCTCTCGAACGGGTG
CAGGTGGATCAGGAGGCAGGTGCCACGCGCAACCCGTTCATCAATGCGGGCGCGCTTGTCGTCACCGATGTGCTTTGCTC
TAGTTTTGCGCAACCTGAACTCGCACTACTCCAAACTTTGAGACAAAGCGCAGATGATGAGCGGGTAGACATTGATCAAA
TAGTCATGCGCTCGGAACGCGAGAGCTGCCACCGCAACGCCGCCATTGCCCACCTACTTAAAAGCTACGGCCGCATCTGC
AACTCAGTCGATACGGTGCTGGATACCTATTGTCGGCAGTGCGCACTAACCATGAATACCCGCCAGATTGCCCGGTGTGC
ATTGCCATTGGCAATTAGCGGAAGGCTTTCAGCTCATCGCGCACGCGAAAGGCTATCAGCAGTGCAACGCCATAGCGTGA
CTGCGTTGATGCTCACATGCGGAACATACAACGCTGCAGGCGATTTTGCCGCGCGCGTTGGATTGCCTATGAAAAGCGGC
GTGGGGGGAGGCATTGTCGCGGTCATTCCCGGGGTTGGCAGTGTGTGTGCGTGGTCGCCCGGTCTCGACGGTGCTGGCAA
TAGCTTGGCCGCCGGACGTGCAATTGAACTATTTGCAAAACATACAGGTTTGTCGGTACTGGGATCACCCGCAAGAACCT
TTAAGGCGCTGTGA

Upstream 100 bases:

>100_bases
GACACCGGCAAGATCCGGCAATGAGCGAACTTCCGGTAGCGCTTGCCGATAGCCGTATCGCGGGTTTCCCCGCTCCGTCG
GGGAATTGACCCCTAGCGAC

Downstream 100 bases:

>100_bases
CAAGCGTTTAGCCTGGATTCAAAACTAATAAGGTACGGCCTACCCGGGTTAGATTTCGACGGAATTCAACATGCGGTCTT
CGGGACAAACCTGTGGCGTA

Product: glutaminase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 297; Mature: 296

Protein sequence:

>297_residues
MPIDDADGLLAHIAAQVRPLLPQGQLPQYIPQLGRVDKMQFGMALLMLDGREAFVGDADVPFSIQSISKLFALMLALERV
QVDQEAGATRNPFINAGALVVTDVLCSSFAQPELALLQTLRQSADDERVDIDQIVMRSERESCHRNAAIAHLLKSYGRIC
NSVDTVLDTYCRQCALTMNTRQIARCALPLAISGRLSAHRARERLSAVQRHSVTALMLTCGTYNAAGDFAARVGLPMKSG
VGGGIVAVIPGVGSVCAWSPGLDGAGNSLAAGRAIELFAKHTGLSVLGSPARTFKAL

Sequences:

>Translated_297_residues
MPIDDADGLLAHIAAQVRPLLPQGQLPQYIPQLGRVDKMQFGMALLMLDGREAFVGDADVPFSIQSISKLFALMLALERV
QVDQEAGATRNPFINAGALVVTDVLCSSFAQPELALLQTLRQSADDERVDIDQIVMRSERESCHRNAAIAHLLKSYGRIC
NSVDTVLDTYCRQCALTMNTRQIARCALPLAISGRLSAHRARERLSAVQRHSVTALMLTCGTYNAAGDFAARVGLPMKSG
VGGGIVAVIPGVGSVCAWSPGLDGAGNSLAAGRAIELFAKHTGLSVLGSPARTFKAL
>Mature_296_residues
PIDDADGLLAHIAAQVRPLLPQGQLPQYIPQLGRVDKMQFGMALLMLDGREAFVGDADVPFSIQSISKLFALMLALERVQ
VDQEAGATRNPFINAGALVVTDVLCSSFAQPELALLQTLRQSADDERVDIDQIVMRSERESCHRNAAIAHLLKSYGRICN
SVDTVLDTYCRQCALTMNTRQIARCALPLAISGRLSAHRARERLSAVQRHSVTALMLTCGTYNAAGDFAARVGLPMKSGV
GGGIVAVIPGVGSVCAWSPGLDGAGNSLAAGRAIELFAKHTGLSVLGSPARTFKAL

Specific function: Unknown

COG id: COG2066

COG function: function code E; Glutaminase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glutaminase family [H]

Homologues:

Organism=Homo sapiens, GI156104878, Length=270, Percent_Identity=32.2222222222222, Blast_Score=130, Evalue=2e-30,
Organism=Homo sapiens, GI20336214, Length=273, Percent_Identity=30.7692307692308, Blast_Score=119, Evalue=3e-27,
Organism=Escherichia coli, GI1787804, Length=302, Percent_Identity=42.0529801324503, Blast_Score=217, Evalue=7e-58,
Organism=Escherichia coli, GI1786693, Length=290, Percent_Identity=33.448275862069, Blast_Score=138, Evalue=5e-34,
Organism=Caenorhabditis elegans, GI17532727, Length=271, Percent_Identity=30.6273062730627, Blast_Score=126, Evalue=2e-29,
Organism=Caenorhabditis elegans, GI17507019, Length=307, Percent_Identity=31.9218241042345, Blast_Score=125, Evalue=2e-29,
Organism=Caenorhabditis elegans, GI193204073, Length=275, Percent_Identity=31.2727272727273, Blast_Score=120, Evalue=6e-28,
Organism=Caenorhabditis elegans, GI193204075, Length=277, Percent_Identity=31.0469314079422, Blast_Score=120, Evalue=9e-28,
Organism=Drosophila melanogaster, GI281363241, Length=276, Percent_Identity=32.6086956521739, Blast_Score=139, Evalue=3e-33,
Organism=Drosophila melanogaster, GI24653164, Length=276, Percent_Identity=32.6086956521739, Blast_Score=139, Evalue=3e-33,
Organism=Drosophila melanogaster, GI24653162, Length=276, Percent_Identity=32.6086956521739, Blast_Score=138, Evalue=4e-33,
Organism=Drosophila melanogaster, GI24653156, Length=276, Percent_Identity=32.6086956521739, Blast_Score=138, Evalue=4e-33,
Organism=Drosophila melanogaster, GI281363239, Length=276, Percent_Identity=32.6086956521739, Blast_Score=138, Evalue=4e-33,
Organism=Drosophila melanogaster, GI24653158, Length=276, Percent_Identity=32.6086956521739, Blast_Score=138, Evalue=5e-33,
Organism=Drosophila melanogaster, GI24653166, Length=276, Percent_Identity=32.6086956521739, Blast_Score=138, Evalue=6e-33,
Organism=Drosophila melanogaster, GI116008307, Length=276, Percent_Identity=32.6086956521739, Blast_Score=137, Evalue=6e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012338
- InterPro:   IPR015868 [H]

Pfam domain/function: PF04960 Glutaminase [H]

EC number: =3.5.1.2 [H]

Molecular weight: Translated: 31622; Mature: 31491

Theoretical pI: Translated: 8.01; Mature: 8.01

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.7 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
2.7 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPIDDADGLLAHIAAQVRPLLPQGQLPQYIPQLGRVDKMQFGMALLMLDGREAFVGDADV
CCCCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHCCHHHHHHCEEEEEECCCHHCCCCCCC
PFSIQSISKLFALMLALERVQVDQEAGATRNPFINAGALVVTDVLCSSFAQPELALLQTL
CCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHH
RQSADDERVDIDQIVMRSERESCHRNAAIAHLLKSYGRICNSVDTVLDTYCRQCALTMNT
HHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCH
RQIARCALPLAISGRLSAHRARERLSAVQRHSVTALMLTCGTYNAAGDFAARVGLPMKSG
HHHHHHHCCHHHCCCHHHHHHHHHHHHHHHHHHHEEEEECCCCCCCCHHHHHHCCCHHCC
VGGGIVAVIPGVGSVCAWSPGLDGAGNSLAAGRAIELFAKHTGLSVLGSPARTFKAL
CCCCEEEEECCCCCHHCCCCCCCCCCCCCCCCHHHHHHHHHCCCHHHCCCHHHHCCC
>Mature Secondary Structure 
PIDDADGLLAHIAAQVRPLLPQGQLPQYIPQLGRVDKMQFGMALLMLDGREAFVGDADV
CCCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHCCHHHHHHCEEEEEECCCHHCCCCCCC
PFSIQSISKLFALMLALERVQVDQEAGATRNPFINAGALVVTDVLCSSFAQPELALLQTL
CCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHH
RQSADDERVDIDQIVMRSERESCHRNAAIAHLLKSYGRICNSVDTVLDTYCRQCALTMNT
HHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCH
RQIARCALPLAISGRLSAHRARERLSAVQRHSVTALMLTCGTYNAAGDFAARVGLPMKSG
HHHHHHHCCHHHCCCHHHHHHHHHHHHHHHHHHHEEEEECCCCCCCCHHHHHHCCCHHCC
VGGGIVAVIPGVGSVCAWSPGLDGAGNSLAAGRAIELFAKHTGLSVLGSPARTFKAL
CCCCEEEEECCCCCHHCCCCCCCCCCCCCCCCHHHHHHHHHCCCHHHCCCHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11823852 [H]