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The map label for this gene is gltC [H]

Identifier: 91790203

GI number: 91790203

Start: 4609701

End: 4610603

Strand: Reverse

Name: gltC [H]

Synonym: Bpro_4368

Alternate gene names: 91790203

Gene position: 4610603-4609701 (Counterclockwise)

Preceding gene: 91790205

Following gene: 91790200

Centisome position: 88.66

GC content: 55.04

Gene sequence:

>903_bases
ATGGATATTGCACGCCTCAAAGCATTGCGAGAACTTTCAATCCGCCAAACGATGGCTGCGGTTGCTGAGGCACTAAACCT
CACCCCGTCGGCTGTTTCCCAACAGATCGCCCAGCTTGAAGAGGAAGTCGGTGTTCCTCTAACCGAGCGCAGAGGCCGTG
GGGTCAAGCTGACTTACGCGGGCGAAGTCTTGGTATCGCATGTGGAGCGCATCATGGGCGTTCTAGATGAGGCCAGCTCG
GAGCTGGCCCTAATACGTAAAGAGATCGCCGGCACCTTGCGGATCGCCGCCTTTGCGACTGCTGCAGCGGCACTGCTCCC
TCCTGTGCTGCAAGCGCTTCGAAAAAGCTATCCGCGTCTTCAGATAACAATTATTGAGATGGAGCCGTCTGAGGGTTTGG
CAGCCCTTGGTTCCTGGAACGTTGATTTGGCAATAGTGGACGATCTTTCCGTCCGTTTGGCCCGTATGGAGAAGACGGTT
CACAAGGTGCGCCTTATTGATGACGAGCTGAAAGTAGTGATGGCAAAGAACCATCATCTTGCGGTCAAAGCATCCATTGT
CCTATCTGAGCTAAAGGATGAGGAGTGGGCGATGGATTCCGCAACTAGTTTCTATGGTGAATTCGTAATGAATCTTTGCC
GCCAAGCCGGCTTCACCCCTCAGGTCAACGCCGCTTGCCGCGGCTCAGAAATCATTGCCGCGATGGTGGCATCCGGTTGC
TCTGTGTCCATCATTCCCGGACTACGCCTTGGGCAGATCTCGCAGCAGTTGGTTGCTCGCCCCCTACGGCCGGCTGTGAC
TCGTCGAATCTCAGTAGCTTTTCGCCAAGGGGAAAGGTCGCATCCCGCCATAAAGGTTTTCGTTGAACAGCTGCTGCGCA
CTGCGCAAACGATGACGCCTTAA

Upstream 100 bases:

>100_bases
AATGTAGGAACGTGCATAGTACGGGTGCTATTCAGGCAATACAATTTATCTTTATTTGATGTATACATTAGGAATATTTA
CTTATTGATCGGGGATGGAT

Downstream 100 bases:

>100_bases
CTCGATCGGTTGCTTCGTAATGCGTGATGGCGGACCACCCACGCATCGTTGTTTAGTCAATCCGATTAAGCATGTGCAAT
AGAGGAGGGTATGTTCGAGG

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 300; Mature: 300

Protein sequence:

>300_residues
MDIARLKALRELSIRQTMAAVAEALNLTPSAVSQQIAQLEEEVGVPLTERRGRGVKLTYAGEVLVSHVERIMGVLDEASS
ELALIRKEIAGTLRIAAFATAAAALLPPVLQALRKSYPRLQITIIEMEPSEGLAALGSWNVDLAIVDDLSVRLARMEKTV
HKVRLIDDELKVVMAKNHHLAVKASIVLSELKDEEWAMDSATSFYGEFVMNLCRQAGFTPQVNAACRGSEIIAAMVASGC
SVSIIPGLRLGQISQQLVARPLRPAVTRRISVAFRQGERSHPAIKVFVEQLLRTAQTMTP

Sequences:

>Translated_300_residues
MDIARLKALRELSIRQTMAAVAEALNLTPSAVSQQIAQLEEEVGVPLTERRGRGVKLTYAGEVLVSHVERIMGVLDEASS
ELALIRKEIAGTLRIAAFATAAAALLPPVLQALRKSYPRLQITIIEMEPSEGLAALGSWNVDLAIVDDLSVRLARMEKTV
HKVRLIDDELKVVMAKNHHLAVKASIVLSELKDEEWAMDSATSFYGEFVMNLCRQAGFTPQVNAACRGSEIIAAMVASGC
SVSIIPGLRLGQISQQLVARPLRPAVTRRISVAFRQGERSHPAIKVFVEQLLRTAQTMTP
>Mature_300_residues
MDIARLKALRELSIRQTMAAVAEALNLTPSAVSQQIAQLEEEVGVPLTERRGRGVKLTYAGEVLVSHVERIMGVLDEASS
ELALIRKEIAGTLRIAAFATAAAALLPPVLQALRKSYPRLQITIIEMEPSEGLAALGSWNVDLAIVDDLSVRLARMEKTV
HKVRLIDDELKVVMAKNHHLAVKASIVLSELKDEEWAMDSATSFYGEFVMNLCRQAGFTPQVNAACRGSEIIAAMVASGC
SVSIIPGLRLGQISQQLVARPLRPAVTRRISVAFRQGERSHPAIKVFVEQLLRTAQTMTP

Specific function: Positive regulator of glutamate biosynthesis (gltAB genes). Negatively regulates its own expression [H]

COG id: COG0583

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI157672245, Length=204, Percent_Identity=31.8627450980392, Blast_Score=93, Evalue=2e-20,
Organism=Escherichia coli, GI1790399, Length=283, Percent_Identity=26.1484098939929, Blast_Score=89, Evalue=3e-19,
Organism=Escherichia coli, GI1790262, Length=290, Percent_Identity=24.1379310344828, Blast_Score=82, Evalue=4e-17,
Organism=Escherichia coli, GI1787879, Length=227, Percent_Identity=26.8722466960352, Blast_Score=82, Evalue=5e-17,
Organism=Escherichia coli, GI2367136, Length=225, Percent_Identity=25.7777777777778, Blast_Score=82, Evalue=6e-17,
Organism=Escherichia coli, GI1787601, Length=244, Percent_Identity=24.5901639344262, Blast_Score=76, Evalue=2e-15,
Organism=Escherichia coli, GI1788706, Length=215, Percent_Identity=30.2325581395349, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1790208, Length=257, Percent_Identity=24.124513618677, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI1789506, Length=201, Percent_Identity=24.8756218905473, Blast_Score=66, Evalue=3e-12,
Organism=Escherichia coli, GI1787530, Length=250, Percent_Identity=24, Blast_Score=64, Evalue=9e-12,
Organism=Escherichia coli, GI1788296, Length=151, Percent_Identity=35.0993377483444, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1788887, Length=294, Percent_Identity=25.8503401360544, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI48994962, Length=106, Percent_Identity=39.622641509434, Blast_Score=62, Evalue=3e-11,
Organism=Escherichia coli, GI1788297, Length=151, Percent_Identity=29.8013245033113, Blast_Score=62, Evalue=6e-11,
Organism=Escherichia coli, GI87081904, Length=184, Percent_Identity=28.804347826087, Blast_Score=61, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 32707; Mature: 32707

Theoretical pI: Translated: 8.86; Mature: 8.86

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDIARLKALRELSIRQTMAAVAEALNLTPSAVSQQIAQLEEEVGVPLTERRGRGVKLTYA
CCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCHHCCCCCEEEEEH
GEVLVSHVERIMGVLDEASSELALIRKEIAGTLRIAAFATAAAALLPPVLQALRKSYPRL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCE
QITIIEMEPSEGLAALGSWNVDLAIVDDLSVRLARMEKTVHKVRLIDDELKVVMAKNHHL
EEEEEEECCCCCCCHHCCCCEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCE
AVKASIVLSELKDEEWAMDSATSFYGEFVMNLCRQAGFTPQVNAACRGSEIIAAMVASGC
EEHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHCCC
SVSIIPGLRLGQISQQLVARPLRPAVTRRISVAFRQGERSHPAIKVFVEQLLRTAQTMTP
CEEECCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MDIARLKALRELSIRQTMAAVAEALNLTPSAVSQQIAQLEEEVGVPLTERRGRGVKLTYA
CCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCHHCCCCCEEEEEH
GEVLVSHVERIMGVLDEASSELALIRKEIAGTLRIAAFATAAAALLPPVLQALRKSYPRL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCE
QITIIEMEPSEGLAALGSWNVDLAIVDDLSVRLARMEKTVHKVRLIDDELKVVMAKNHHL
EEEEEEECCCCCCCHHCCCCEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCE
AVKASIVLSELKDEEWAMDSATSFYGEFVMNLCRQAGFTPQVNAACRGSEIIAAMVASGC
EEHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHCCC
SVSIIPGLRLGQISQQLVARPLRPAVTRRISVAFRQGERSHPAIKVFVEQLLRTAQTMTP
CEEECCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2548995; 9384377 [H]