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The map label for this gene is pheC [H]

Identifier: 91790052

GI number: 91790052

Start: 4432927

End: 4433748

Strand: Direct

Name: pheC [H]

Synonym: Bpro_4214

Alternate gene names: 91790052

Gene position: 4432927-4433748 (Clockwise)

Preceding gene: 91790051

Following gene: 91790053

Centisome position: 85.24

GC content: 63.38

Gene sequence:

>822_bases
ATGTCATTTCGTCAGAAACTGCAGCCCCGCCTGGTCGCACTCGGCCTTGTTTCGGCCGCGTCCTTCGTCATGCTTTCCGG
CGCCTCGGCGCAGACTGCTGCTGCCAGCGTGCCGCCGGCTTCCAGCCTGGATGCCGTGCAAAAGGCGGGGGTGCTGCGCA
TCTGCACGCCGGGCGACTACAAGCCCTTCAGCTTCCAGAAGCCTGATGGCGCCTTTGAGGGCATTGACGTGGACCTGATG
GCCTCGCTGACGGCCAGCCTGGGCGTGAAGCCCGAGTGGGTCAAGACCAGCTGGTCCAACCTCATGCCCGACATGGTGGC
CGGCAAGTGCGACCTGGCCGTCGGCGGGATCTCGGTGACCACCGAGCGGCAAAAGAAAGCCTTCTTCAGCACCGCCTACA
TGGTCAACGGCAAGACGCCGATTGCCCGCTGCGCCGATGTTGCCAAATACCAGACGGTGGCCGACATCGACAAGCCGGCG
ACGCGCGTGATCTTCAACCCCGGCGGCAGCAATGAGCGCTTTGCCCGCGCCAACTTCAAGCAGGCGCAGATGCGGCTGAA
CCCCGAGAACCTGACGATTTTTGACGAAATCCTGGCCAACCGCGCGGATGTGTTCGTCACGGAATCGGCCGAAGCCATCA
CCCAGCAACGGCTCAAGCCCGGGCTGTGCGCCATCAACCCCGACAAGCCCCTGCAATACGGCGAAATGGCCTATCTGCTG
CCGCGTGGCGATGTGACCTTCAAGGCCTATGTAGACCAGTGGCTGCACCTGGCCAAGGCCAGCGGCGAGTACCAGCGGGT
GGAAGGACAATGGCTGAAGTAG

Upstream 100 bases:

>100_bases
AGGCACTGTTCGAAAGCATCGAGCTGGACCAGATGCGCCGAGGGGTTTTGGCGAGTGCACAATAAAGTCCGTCCATTTAC
CCACCCTCCCGGAGATTGCC

Downstream 100 bases:

>100_bases
CAGGCGGCGCCCCCGAACCGGTGGTGTACGGTCAATCCGACCGGCCACCGCGGGGCGACTATTCACGCGGCGGCCAGGTC
AGGGCCGACTACACCTGCCC

Product: cyclohexadienyl dehydratase

Products: NA

Alternate protein names: Prephenate dehydratase; Arogenate dehydratase [H]

Number of amino acids: Translated: 273; Mature: 272

Protein sequence:

>273_residues
MSFRQKLQPRLVALGLVSAASFVMLSGASAQTAAASVPPASSLDAVQKAGVLRICTPGDYKPFSFQKPDGAFEGIDVDLM
ASLTASLGVKPEWVKTSWSNLMPDMVAGKCDLAVGGISVTTERQKKAFFSTAYMVNGKTPIARCADVAKYQTVADIDKPA
TRVIFNPGGSNERFARANFKQAQMRLNPENLTIFDEILANRADVFVTESAEAITQQRLKPGLCAINPDKPLQYGEMAYLL
PRGDVTFKAYVDQWLHLAKASGEYQRVEGQWLK

Sequences:

>Translated_273_residues
MSFRQKLQPRLVALGLVSAASFVMLSGASAQTAAASVPPASSLDAVQKAGVLRICTPGDYKPFSFQKPDGAFEGIDVDLM
ASLTASLGVKPEWVKTSWSNLMPDMVAGKCDLAVGGISVTTERQKKAFFSTAYMVNGKTPIARCADVAKYQTVADIDKPA
TRVIFNPGGSNERFARANFKQAQMRLNPENLTIFDEILANRADVFVTESAEAITQQRLKPGLCAINPDKPLQYGEMAYLL
PRGDVTFKAYVDQWLHLAKASGEYQRVEGQWLK
>Mature_272_residues
SFRQKLQPRLVALGLVSAASFVMLSGASAQTAAASVPPASSLDAVQKAGVLRICTPGDYKPFSFQKPDGAFEGIDVDLMA
SLTASLGVKPEWVKTSWSNLMPDMVAGKCDLAVGGISVTTERQKKAFFSTAYMVNGKTPIARCADVAKYQTVADIDKPAT
RVIFNPGGSNERFARANFKQAQMRLNPENLTIFDEILANRADVFVTESAEAITQQRLKPGLCAINPDKPLQYGEMAYLLP
RGDVTFKAYVDQWLHLAKASGEYQRVEGQWLK

Specific function: Forms alternative pathway for phenylalanine biosynthesis. Can catalyze two reactions:prephenate dehydratase and arogenate dehydratase. May have a role in chemotaxis or transport [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial solute-binding protein 3 family [H]

Homologues:

Organism=Escherichia coli, GI1788228, Length=207, Percent_Identity=24.1545893719807, Blast_Score=81, Evalue=9e-17,
Organism=Escherichia coli, GI1787031, Length=249, Percent_Identity=24.8995983935743, Blast_Score=71, Evalue=8e-14,

Paralogues:

None

Copy number: 1920 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1060 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 80 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015683
- InterPro:   IPR001638
- InterPro:   IPR018313 [H]

Pfam domain/function: PF00497 SBP_bac_3 [H]

EC number: =4.2.1.51; =4.2.1.91 [H]

Molecular weight: Translated: 29718; Mature: 29587

Theoretical pI: Translated: 9.11; Mature: 9.11

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSFRQKLQPRLVALGLVSAASFVMLSGASAQTAAASVPPASSLDAVQKAGVLRICTPGDY
CCHHHHHCHHHHHHHHHHHHHHHEECCCCCCCHHCCCCCCCHHHHHHHCCEEEEECCCCC
KPFSFQKPDGAFEGIDVDLMASLTASLGVKPEWVKTSWSNLMPDMVAGKCDLAVGGISVT
CCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCHHHHCCHHHCCHHHHCCCCCEEECCEEEE
TERQKKAFFSTAYMVNGKTPIARCADVAKYQTVADIDKPATRVIFNPGGSNERFARANFK
CHHHHHHHHHEEEEECCCCHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCEECCCHH
QAQMRLNPENLTIFDEILANRADVFVTESAEAITQQRLKPGLCAINPDKPLQYGEMAYLL
HHHEEECCCCCHHHHHHHCCCCCEEEECCHHHHHHHHCCCCCEEECCCCCCCCCCEEEEE
PRGDVTFKAYVDQWLHLAKASGEYQRVEGQWLK
CCCCEEHHHHHHHHHHHHHCCCCEEECCCCCCC
>Mature Secondary Structure 
SFRQKLQPRLVALGLVSAASFVMLSGASAQTAAASVPPASSLDAVQKAGVLRICTPGDY
CHHHHHCHHHHHHHHHHHHHHHEECCCCCCCHHCCCCCCCHHHHHHHCCEEEEECCCCC
KPFSFQKPDGAFEGIDVDLMASLTASLGVKPEWVKTSWSNLMPDMVAGKCDLAVGGISVT
CCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCHHHHCCHHHCCHHHHCCCCCEEECCEEEE
TERQKKAFFSTAYMVNGKTPIARCADVAKYQTVADIDKPATRVIFNPGGSNERFARANFK
CHHHHHHHHHEEEEECCCCHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCEECCCHH
QAQMRLNPENLTIFDEILANRADVFVTESAEAITQQRLKPGLCAINPDKPLQYGEMAYLL
HHHEEECCCCCHHHHHHHCCCCCEEEECCHHHHHHHHCCCCCEEECCCCCCCCCCEEEEE
PRGDVTFKAYVDQWLHLAKASGEYQRVEGQWLK
CCCCEEHHHHHHHHHHHHHCCCCEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1733946; 10984043; 8515238; 7604006 [H]