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The map label for this gene is gntK [H]

Identifier: 91785187

GI number: 91785187

Start: 4221918

End: 4222415

Strand: Reverse

Name: gntK [H]

Synonym: Bxe_A0592

Alternate gene names: 91785187

Gene position: 4222415-4221918 (Counterclockwise)

Preceding gene: 91785188

Following gene: 91785184

Centisome position: 86.25

GC content: 61.65

Gene sequence:

>498_bases
ATGATTCTGATCGCAATGGGCGTGTCGGGCGCCGGCAAGACGAGAATTGGCGAAATGCTGGCGGAGCGCCTGCACTGCGC
GTTCACCGACGGCGACGCATTTCACAGCGCCGCCAACAAGGAGAAAATGCACCACGGCATTCCGCTGACGGATGAAGACC
GCTGGCCCTGGCTGAAAACGATCCGCGCGGCGATTGAGGAGAAGCAGACGGCGGGCGAGACGGCGGTGTTCACGTGTTCG
TCGCTGAAGCGCTCGTATCGCGACGTTCTGCGCGACGGCGACAAGGACGTGTGCTTCGTCTACCTCAAGGGTTCGCGTGA
GGTGCTGGAGCAGCGCCTGACCACGCGCACCGGCCATTTTTTCGATCCGTCGCTGCTGCAAAGCCAGCTCGATACGCTCG
AAGAACCGGGCGCCGATGAGGCGATCACGGTAAGCATCGAACTGTCGCCGGAAGAGATCGTCGACAGCGTGCTGATTCAG
GTCGAAGCGCGTAAGTGA

Upstream 100 bases:

>100_bases
GGGCAGACCTTCAAGACATGGTCGCTCCTCGAAACCATCATCTCGCTGATGGGTCTGGGTTTGACCTTCGCACTCGCGAC
GGTCGTGTAAGGAGTTTTTG

Downstream 100 bases:

>100_bases
GTTTGCCTGGTTGCAGGTAGATAGATGTAAAAAAACCGCTTCTCGGAGCGGTTTTTTCATGCCTGGTGCAACAGGCGGGC
AACAGGCGGCCAACAACCGA

Product: gluconate kinase

Products: NA

Alternate protein names: Gluconate kinase 2 [H]

Number of amino acids: Translated: 165; Mature: 165

Protein sequence:

>165_residues
MILIAMGVSGAGKTRIGEMLAERLHCAFTDGDAFHSAANKEKMHHGIPLTDEDRWPWLKTIRAAIEEKQTAGETAVFTCS
SLKRSYRDVLRDGDKDVCFVYLKGSREVLEQRLTTRTGHFFDPSLLQSQLDTLEEPGADEAITVSIELSPEEIVDSVLIQ
VEARK

Sequences:

>Translated_165_residues
MILIAMGVSGAGKTRIGEMLAERLHCAFTDGDAFHSAANKEKMHHGIPLTDEDRWPWLKTIRAAIEEKQTAGETAVFTCS
SLKRSYRDVLRDGDKDVCFVYLKGSREVLEQRLTTRTGHFFDPSLLQSQLDTLEEPGADEAITVSIELSPEEIVDSVLIQ
VEARK
>Mature_165_residues
MILIAMGVSGAGKTRIGEMLAERLHCAFTDGDAFHSAANKEKMHHGIPLTDEDRWPWLKTIRAAIEEKQTAGETAVFTCS
SLKRSYRDVLRDGDKDVCFVYLKGSREVLEQRLTTRTGHFFDPSLLQSQLDTLEEPGADEAITVSIELSPEEIVDSVLIQ
VEARK

Specific function: Gluconate utilization system GNT-I. [C]

COG id: COG3265

COG function: function code G; Gluconate kinase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the gluconokinase gntK/gntV family [H]

Homologues:

Organism=Homo sapiens, GI299758445, Length=175, Percent_Identity=39.4285714285714, Blast_Score=132, Evalue=2e-31,
Organism=Escherichia coli, GI87082265, Length=159, Percent_Identity=44.6540880503145, Blast_Score=150, Evalue=6e-38,
Organism=Escherichia coli, GI1790719, Length=147, Percent_Identity=46.9387755102041, Blast_Score=138, Evalue=2e-34,
Organism=Caenorhabditis elegans, GI25146487, Length=161, Percent_Identity=43.4782608695652, Blast_Score=132, Evalue=8e-32,
Organism=Saccharomyces cerevisiae, GI6320454, Length=150, Percent_Identity=37.3333333333333, Blast_Score=101, Evalue=5e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000623
- InterPro:   IPR006001 [H]

Pfam domain/function: PF01202 SKI [H]

EC number: =2.7.1.12 [H]

Molecular weight: Translated: 18406; Mature: 18406

Theoretical pI: Translated: 4.93; Mature: 4.93

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MILIAMGVSGAGKTRIGEMLAERLHCAFTDGDAFHSAANKEKMHHGIPLTDEDRWPWLKT
CEEEEECCCCCCHHHHHHHHHHHHHEECCCCHHHHHHHHHHHHHCCCCCCCCCCCHHHHH
IRAAIEEKQTAGETAVFTCSSLKRSYRDVLRDGDKDVCFVYLKGSREVLEQRLTTRTGHF
HHHHHHHHHCCCCHHEEEHHHHHHHHHHHHHCCCCCEEEEEECCCHHHHHHHHHHHCCCC
FDPSLLQSQLDTLEEPGADEAITVSIELSPEEIVDSVLIQVEARK
CCHHHHHHHHHHHCCCCCCCEEEEEEEECHHHHHHHHHHEEECCC
>Mature Secondary Structure
MILIAMGVSGAGKTRIGEMLAERLHCAFTDGDAFHSAANKEKMHHGIPLTDEDRWPWLKT
CEEEEECCCCCCHHHHHHHHHHHHHEECCCCHHHHHHHHHHHHHCCCCCCCCCCCHHHHH
IRAAIEEKQTAGETAVFTCSSLKRSYRDVLRDGDKDVCFVYLKGSREVLEQRLTTRTGHF
HHHHHHHHHCCCCHHEEEHHHHHHHHHHHHHCCCCCEEEEEECCCHHHHHHHHHHHCCCC
FDPSLLQSQLDTLEEPGADEAITVSIELSPEEIVDSVLIQVEARK
CCHHHHHHHHHHHCCCCCCCEEEEEEEECHHHHHHHHHHEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9135111; 9278503; 8655507; 11468405 [H]