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The map label for this gene is gnuT [H]

Identifier: 91785188

GI number: 91785188

Start: 4222426

End: 4223823

Strand: Reverse

Name: gnuT [H]

Synonym: Bxe_A0591

Alternate gene names: 91785188

Gene position: 4223823-4222426 (Counterclockwise)

Preceding gene: 91785189

Following gene: 91785187

Centisome position: 86.27

GC content: 62.66

Gene sequence:

>1398_bases
ATGGAAGCTGTCCACGGCAGCATGCTGCTGGTCTTCGCGGCGATCGCCATCGCATTGCTGATCCTGCTGATCACGCGCTA
CAAGGTTTACCCGTTCCTCGTTCTGATCATCGTGTCGCTGCTGCTGGGTCTCGCATCCGGCATGCCGATCGGCACCATCG
TCAAATCGTTCGAAACGGGCAACGGCAATACGCTTGGCCACATCGCGATCGTGGTCGGCCTCGGCACGATGCTCGGCAAG
ATGATGGCCGAATCCGGCGGCGCGGAGCGCATCGCCACCACGCTGATCGACTTCTTCGGCGAGAAGAACATCCACTGGGC
GATGATGATCGTCGCGATCATCGTGGGCTTGCCGGTGTTCTTCGAAGTCGGCTTCGTGCTGCTGATTCCGATCGCTTTCA
ACGTCGCGAAGCGCACCAACAAGTCGTTGCTGCTGGTCGGCTTGCCAATGGTCGCGGGTCTGTCCGTCGTGCACGGGCTG
CTTCCGCCGCACCCGGCCGCGATGCTCGCGGTGCAGGCATATCACGCGGATATCGGCAGGACCATCGCCTATGGCCTGAT
TGTCGGCGTGCCGACCGCGATCGTCGCGGGTCCGTTGTTTGCGTTGATGATCAGCCGCTATATCAAGCTGCCGAAAGACA
ACGCGCTCGCCTCGCAATTTCTCGGCGCCGATGAAACCGGTGCGGCGAACAACGGCAACGGCGAGCAAAAGACCGCGCCC
AGGCGCGAACTGCCGAGCTTCGGCGTGACGCTGTTCACGATCCTGTTGCCGGTTATCCTGATGCTGGTGGGCAGTTGGGC
CGACCTCGTGTTCACGCCGAAGACCCTCGCGAACGATCTGCTGCGTTTCGTCGGCAATTCGGATGTGGCGCTGCTGGTCG
CGGTGCTGGTCAGTTTCTGGACCTTTGGTGCGAGCCGTGGCTTCGATCGCGAGCAGATCCAGAAATTCTGCGGCGAATGT
CTCGCGCCGATCGCGGGCATTACGCTGATTGTCGGCGCGGGCGGCGGCTTTGGGCGCGTGCTGATGGATAGCGGCATTTC
GAAGGAGATCGTCAACGCGGCGACGTCGGCGCATCTGTCGCCGCTGCTGTTCGGCTGGCTGGTCGCGGCGCTGATTCGCC
TGGCCACCGGCTCGGCGACGGTCGCGATGACCACCGCTTGCGGCATCGTCGCGCCGATCGCGGCGGCGGGCGCGGTGCAG
GTGAAGCCGGAACTGCTGGTGCTGGCCACGGGTTCGGGCTCGCTGATCTTTTCGCACGTGAACGACGGCGGTTTCTGGCT
GATCAAGGAATACTTCGGGATGACGGTGGGGCAGACCTTCAAGACATGGTCGCTCCTCGAAACCATCATCTCGCTGATGG
GTCTGGGTTTGACCTTCGCACTCGCGACGGTCGTGTAA

Upstream 100 bases:

>100_bases
GCGCGGTGAGCCCGGTTTCAGGGTGCCGCACAGGTCACCGTGAGACAAGGTGCTGACCGTGTTCCGCACTCAGAATCAAT
AACGCAAAAGGAGGAGCTTC

Downstream 100 bases:

>100_bases
GGAGTTTTTGATGATTCTGATCGCAATGGGCGTGTCGGGCGCCGGCAAGACGAGAATTGGCGAAATGCTGGCGGAGCGCC
TGCACTGCGCGTTCACCGAC

Product: Na+/gluconate symporter, GntP

Products: Proton [Cytoplasm]; gluconate [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 465; Mature: 465

Protein sequence:

>465_residues
MEAVHGSMLLVFAAIAIALLILLITRYKVYPFLVLIIVSLLLGLASGMPIGTIVKSFETGNGNTLGHIAIVVGLGTMLGK
MMAESGGAERIATTLIDFFGEKNIHWAMMIVAIIVGLPVFFEVGFVLLIPIAFNVAKRTNKSLLLVGLPMVAGLSVVHGL
LPPHPAAMLAVQAYHADIGRTIAYGLIVGVPTAIVAGPLFALMISRYIKLPKDNALASQFLGADETGAANNGNGEQKTAP
RRELPSFGVTLFTILLPVILMLVGSWADLVFTPKTLANDLLRFVGNSDVALLVAVLVSFWTFGASRGFDREQIQKFCGEC
LAPIAGITLIVGAGGGFGRVLMDSGISKEIVNAATSAHLSPLLFGWLVAALIRLATGSATVAMTTACGIVAPIAAAGAVQ
VKPELLVLATGSGSLIFSHVNDGGFWLIKEYFGMTVGQTFKTWSLLETIISLMGLGLTFALATVV

Sequences:

>Translated_465_residues
MEAVHGSMLLVFAAIAIALLILLITRYKVYPFLVLIIVSLLLGLASGMPIGTIVKSFETGNGNTLGHIAIVVGLGTMLGK
MMAESGGAERIATTLIDFFGEKNIHWAMMIVAIIVGLPVFFEVGFVLLIPIAFNVAKRTNKSLLLVGLPMVAGLSVVHGL
LPPHPAAMLAVQAYHADIGRTIAYGLIVGVPTAIVAGPLFALMISRYIKLPKDNALASQFLGADETGAANNGNGEQKTAP
RRELPSFGVTLFTILLPVILMLVGSWADLVFTPKTLANDLLRFVGNSDVALLVAVLVSFWTFGASRGFDREQIQKFCGEC
LAPIAGITLIVGAGGGFGRVLMDSGISKEIVNAATSAHLSPLLFGWLVAALIRLATGSATVAMTTACGIVAPIAAAGAVQ
VKPELLVLATGSGSLIFSHVNDGGFWLIKEYFGMTVGQTFKTWSLLETIISLMGLGLTFALATVV
>Mature_465_residues
MEAVHGSMLLVFAAIAIALLILLITRYKVYPFLVLIIVSLLLGLASGMPIGTIVKSFETGNGNTLGHIAIVVGLGTMLGK
MMAESGGAERIATTLIDFFGEKNIHWAMMIVAIIVGLPVFFEVGFVLLIPIAFNVAKRTNKSLLLVGLPMVAGLSVVHGL
LPPHPAAMLAVQAYHADIGRTIAYGLIVGVPTAIVAGPLFALMISRYIKLPKDNALASQFLGADETGAANNGNGEQKTAP
RRELPSFGVTLFTILLPVILMLVGSWADLVFTPKTLANDLLRFVGNSDVALLVAVLVSFWTFGASRGFDREQIQKFCGEC
LAPIAGITLIVGAGGGFGRVLMDSGISKEIVNAATSAHLSPLLFGWLVAALIRLATGSATVAMTTACGIVAPIAAAGAVQ
VKPELLVLATGSGSLIFSHVNDGGFWLIKEYFGMTVGQTFKTWSLLETIISLMGLGLTFALATVV

Specific function: Part Of The Gluconate Utilization System Gnt-I; High- Affinity Intake Of Gluconate. [C]

COG id: COG2610

COG function: function code GE; H+/gluconate symporter and related permeases

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the gntP permease family [H]

Homologues:

Organism=Escherichia coli, GI48994935, Length=448, Percent_Identity=45.7589285714286, Blast_Score=367, Evalue=1e-103,
Organism=Escherichia coli, GI1790716, Length=448, Percent_Identity=43.0803571428571, Blast_Score=358, Evalue=1e-100,
Organism=Escherichia coli, GI2367370, Length=430, Percent_Identity=39.7674418604651, Blast_Score=300, Evalue=1e-82,
Organism=Escherichia coli, GI1788707, Length=456, Percent_Identity=38.1578947368421, Blast_Score=286, Evalue=3e-78,
Organism=Escherichia coli, GI1790776, Length=444, Percent_Identity=35.1351351351351, Blast_Score=271, Evalue=6e-74,
Organism=Escherichia coli, GI48994939, Length=450, Percent_Identity=35.5555555555556, Blast_Score=249, Evalue=4e-67,
Organism=Escherichia coli, GI1789097, Length=457, Percent_Identity=33.2603938730853, Blast_Score=229, Evalue=3e-61,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003474 [H]

Pfam domain/function: PF02447 GntP_permease [H]

EC number: NA

Molecular weight: Translated: 48743; Mature: 48743

Theoretical pI: Translated: 8.47; Mature: 8.47

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEAVHGSMLLVFAAIAIALLILLITRYKVYPFLVLIIVSLLLGLASGMPIGTIVKSFETG
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCC
NGNTLGHIAIVVGLGTMLGKMMAESGGAERIATTLIDFFGEKNIHWAMMIVAIIVGLPVF
CCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHH
FEVGFVLLIPIAFNVAKRTNKSLLLVGLPMVAGLSVVHGLLPPHPAAMLAVQAYHADIGR
HHHHHHHHHHHHHHHHHHCCCCEEEECCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHH
TIAYGLIVGVPTAIVAGPLFALMISRYIKLPKDNALASQFLGADETGAANNGNGEQKTAP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCCCCCCCCCCCCCCCCCC
RRELPSFGVTLFTILLPVILMLVGSWADLVFTPKTLANDLLRFVGNSDVALLVAVLVSFW
HHHCCCCHHHHHHHHHHHHHHHHCCCHHHEECHHHHHHHHHHHHCCCCHHHHHHHHHHHH
TFGASRGFDREQIQKFCGECLAPIAGITLIVGAGGGFGRVLMDSGISKEIVNAATSAHLS
HHCCCCCCCHHHHHHHHHHHHHHHHCCEEEEECCCCHHHHHHHCCCHHHHHHHHHHHHHH
PLLFGWLVAALIRLATGSATVAMTTACGIVAPIAAAGAVQVKPELLVLATGSGSLIFSHV
HHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCEEECCCEEEEEECCCCEEEEEE
NDGGFWLIKEYFGMTVGQTFKTWSLLETIISLMGLGLTFALATVV
CCCCEEHHHHHHCCHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MEAVHGSMLLVFAAIAIALLILLITRYKVYPFLVLIIVSLLLGLASGMPIGTIVKSFETG
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCC
NGNTLGHIAIVVGLGTMLGKMMAESGGAERIATTLIDFFGEKNIHWAMMIVAIIVGLPVF
CCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHH
FEVGFVLLIPIAFNVAKRTNKSLLLVGLPMVAGLSVVHGLLPPHPAAMLAVQAYHADIGR
HHHHHHHHHHHHHHHHHHCCCCEEEECCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHH
TIAYGLIVGVPTAIVAGPLFALMISRYIKLPKDNALASQFLGADETGAANNGNGEQKTAP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCCCCCCCCCCCCCCCCCC
RRELPSFGVTLFTILLPVILMLVGSWADLVFTPKTLANDLLRFVGNSDVALLVAVLVSFW
HHHCCCCHHHHHHHHHHHHHHHHCCCHHHEECHHHHHHHHHHHHCCCCHHHHHHHHHHHH
TFGASRGFDREQIQKFCGECLAPIAGITLIVGAGGGFGRVLMDSGISKEIVNAATSAHLS
HHCCCCCCCHHHHHHHHHHHHHHHHCCEEEEECCCCHHHHHHHCCCHHHHHHHHHHHHHH
PLLFGWLVAALIRLATGSATVAMTTACGIVAPIAAAGAVQVKPELLVLATGSGSLIFSHV
HHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCEEECCCEEEEEECCCCEEEEEE
NDGGFWLIKEYFGMTVGQTFKTWSLLETIISLMGLGLTFALATVV
CCCCEEHHHHHHCCHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; gluconate [Periplasm] [C]

Specific reaction: Proton [Periplasm] + gluconate [Periplasm] = Proton [Cytoplasm] + gluconate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]