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The map label for this gene is qseD [H]

Identifier: 91785184

GI number: 91785184

Start: 4218288

End: 4219244

Strand: Reverse

Name: qseD [H]

Synonym: Bxe_A0595

Alternate gene names: 91785184

Gene position: 4219244-4218288 (Counterclockwise)

Preceding gene: 91785187

Following gene: 91785183

Centisome position: 86.18

GC content: 66.56

Gene sequence:

>957_bases
ATGGAACTGAAATGGCTCGAAGACTTCGTCTCGCTCGCGGAAACGCGTAGTTTCAGTCGTTCGGCGGAGTTGCGGCACGT
CACGCAGCCGGCTTTCTCACGGCGGATCCAGGCGCTGGAAGCATGGCTCGGCACGGAACTGATCGACCGTTCGGTTTACC
CGACGCGGCTGACGGCGGCCGGCCAGGTGTTCAACGAGCAGGCGCTCGCCATGCTGTCGCAATTCCACGAGGCGCGGGCG
TTGCTGCGCGGCCATACGGCGACGCCGCAGGCGACCATCGAGTTCGCGGTGCCGCATACGCTGTCCTTGACTTACTTTCC
GCGCTGGCTGCAGCGTATCGAAGCGCAGATGGGCCCGATCCATACGCGGCTGCGCGCGCTGAACGTGCACGATGCGGCGT
TGTCGCTCGTGGAAGGCGGCTGCGATCTGATGATGGGCTATCACCATCCGAGCCACCCGGTCGCCCTCGATCCGGGCCGC
TACGACATGCTGACGCTCGGCAACGAGCCGATCAGTCCGTTTTCGGCGCCCGGCCGCGCGGGCCGGCCGCGTCACACGTT
GCCGGGCAGCGCCGAGGCGCCCACGCCGTATCTGTCCTATACGCCGAACGCCTATCTGGGCCGCATGACCGAAGTGATCC
TGGCCAACGCGCCGGAGCGTCTCTATCTCGACCGGCTCTATGAAACCGACATGGCCGAAGGACTCAAGGCGATGGCGCTG
GCCGGACACGGCATCGCCTTCCTGCCGCACAGCGCGGTGGAAGACGCGGTCGCCGACGGCAAGCTGATCCGCCTCGACCG
CGCCACCCGCGGCACACCGGAAGGCCAGCTCACGCTGACAATGGAGATCCGTCTCTATCGCGACAAGCTCGCGGCGAAGA
GCGACGATGCCCGCCAGATCCTCGTGCGTCAGTTGTGGGACGTGGTGTCGCAGGAACTGGCGCCGGACGCGCCCTGA

Upstream 100 bases:

>100_bases
TCGCGGGCAGACATGGCCGGACCTTGCCGCGTCGCCGTGGTCCGCTTCGCGACAGCATCTAGAATGCTGACTTCTTCCCT
CCGCTGGTGGCAGGCCCCGC

Downstream 100 bases:

>100_bases
ACCTGCGTCCTTACGACGCGAATTTGCAGCTTCCCGATGGTTATGCAAAAAAAACATAATCGGATAAGGAAACGGCATTG
GATTTCAAAACGGCGTTTTT

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: Quorum-sensing regulator protein D [H]

Number of amino acids: Translated: 318; Mature: 318

Protein sequence:

>318_residues
MELKWLEDFVSLAETRSFSRSAELRHVTQPAFSRRIQALEAWLGTELIDRSVYPTRLTAAGQVFNEQALAMLSQFHEARA
LLRGHTATPQATIEFAVPHTLSLTYFPRWLQRIEAQMGPIHTRLRALNVHDAALSLVEGGCDLMMGYHHPSHPVALDPGR
YDMLTLGNEPISPFSAPGRAGRPRHTLPGSAEAPTPYLSYTPNAYLGRMTEVILANAPERLYLDRLYETDMAEGLKAMAL
AGHGIAFLPHSAVEDAVADGKLIRLDRATRGTPEGQLTLTMEIRLYRDKLAAKSDDARQILVRQLWDVVSQELAPDAP

Sequences:

>Translated_318_residues
MELKWLEDFVSLAETRSFSRSAELRHVTQPAFSRRIQALEAWLGTELIDRSVYPTRLTAAGQVFNEQALAMLSQFHEARA
LLRGHTATPQATIEFAVPHTLSLTYFPRWLQRIEAQMGPIHTRLRALNVHDAALSLVEGGCDLMMGYHHPSHPVALDPGR
YDMLTLGNEPISPFSAPGRAGRPRHTLPGSAEAPTPYLSYTPNAYLGRMTEVILANAPERLYLDRLYETDMAEGLKAMAL
AGHGIAFLPHSAVEDAVADGKLIRLDRATRGTPEGQLTLTMEIRLYRDKLAAKSDDARQILVRQLWDVVSQELAPDAP
>Mature_318_residues
MELKWLEDFVSLAETRSFSRSAELRHVTQPAFSRRIQALEAWLGTELIDRSVYPTRLTAAGQVFNEQALAMLSQFHEARA
LLRGHTATPQATIEFAVPHTLSLTYFPRWLQRIEAQMGPIHTRLRALNVHDAALSLVEGGCDLMMGYHHPSHPVALDPGR
YDMLTLGNEPISPFSAPGRAGRPRHTLPGSAEAPTPYLSYTPNAYLGRMTEVILANAPERLYLDRLYETDMAEGLKAMAL
AGHGIAFLPHSAVEDAVADGKLIRLDRATRGTPEGQLTLTMEIRLYRDKLAAKSDDARQILVRQLWDVVSQELAPDAP

Specific function: Down-regulates expression of the flagellar regulon, decreasing motility [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790783, Length=286, Percent_Identity=34.965034965035, Blast_Score=155, Evalue=4e-39,
Organism=Escherichia coli, GI145693193, Length=272, Percent_Identity=24.6323529411765, Blast_Score=65, Evalue=4e-12,
Organism=Escherichia coli, GI1788887, Length=79, Percent_Identity=41.7721518987342, Blast_Score=63, Evalue=3e-11,
Organism=Escherichia coli, GI1787879, Length=266, Percent_Identity=28.1954887218045, Blast_Score=61, Evalue=8e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 35352; Mature: 35352

Theoretical pI: Translated: 6.66; Mature: 6.66

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MELKWLEDFVSLAETRSFSRSAELRHVTQPAFSRRIQALEAWLGTELIDRSVYPTRLTAA
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHH
GQVFNEQALAMLSQFHEARALLRGHTATPQATIEFAVPHTLSLTYFPRWLQRIEAQMGPI
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCEEEHHHHHHHHHHHHHHHCHH
HTRLRALNVHDAALSLVEGGCDLMMGYHHPSHPVALDPGRYDMLTLGNEPISPFSAPGRA
HHHHHHCCHHHHHHHHHHCCCCEEECCCCCCCCEEECCCCEEEEEECCCCCCCCCCCCCC
GRPRHTLPGSAEAPTPYLSYTPNAYLGRMTEVILANAPERLYLDRLYETDMAEGLKAMAL
CCCCCCCCCCCCCCCCCEECCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHH
AGHGIAFLPHSAVEDAVADGKLIRLDRATRGTPEGQLTLTMEIRLYRDKLAAKSDDARQI
CCCCEEECCCHHHHHHHCCCCEEEEECCCCCCCCCEEEEEEEEEEHHHHHHCCCCHHHHH
LVRQLWDVVSQELAPDAP
HHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MELKWLEDFVSLAETRSFSRSAELRHVTQPAFSRRIQALEAWLGTELIDRSVYPTRLTAA
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHH
GQVFNEQALAMLSQFHEARALLRGHTATPQATIEFAVPHTLSLTYFPRWLQRIEAQMGPI
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCEEEHHHHHHHHHHHHHHHCHH
HTRLRALNVHDAALSLVEGGCDLMMGYHHPSHPVALDPGRYDMLTLGNEPISPFSAPGRA
HHHHHHCCHHHHHHHHHHCCCCEEECCCCCCCCEEECCCCEEEEEECCCCCCCCCCCCCC
GRPRHTLPGSAEAPTPYLSYTPNAYLGRMTEVILANAPERLYLDRLYETDMAEGLKAMAL
CCCCCCCCCCCCCCCCCEECCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHH
AGHGIAFLPHSAVEDAVADGKLIRLDRATRGTPEGQLTLTMEIRLYRDKLAAKSDDARQI
CCCCEEECCCHHHHHHHCCCCEEEEECCCCCCCCCEEEEEEEEEEHHHHHHCCCCHHHHH
LVRQLWDVVSQELAPDAP
HHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7610040; 9278503; 7876157 [H]