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The map label for this gene is cysH [H]

Identifier: 87200573

GI number: 87200573

Start: 2762385

End: 2763197

Strand: Direct

Name: cysH [H]

Synonym: Saro_2560

Alternate gene names: 87200573

Gene position: 2762385-2763197 (Clockwise)

Preceding gene: 87200572

Following gene: 87200574

Centisome position: 77.56

GC content: 65.44

Gene sequence:

>813_bases
ATGGACAGCACCGTGACCCGCAAGATCGACCTGCTCGACACCGCGCCGCGCTTTACCGAGACGGACGCGATCCGCCTCAA
CAACCTGTTCCGGGGCACCGACACGCACGACATGCTGCGTTCGGTGATCCGCGACGGGCTGGCGGGCGACCTCGCGGTCG
TGTCGAGCTTCGGCGCGGAAAGCGCGGTGCTGCTCCACCTGATCGCCGAAGTCGACCCTTCGGTGCCGGTCCTGTTTCTC
GAAACGGGCAAGCATTTCCGCGAGACCGTTGCCTATCGCGACGAGTTGATCGGCTTCCTGGGCATGACCAACCTGCAGAT
CATCGAACCCGACGCGGCGGTCATCGCCAAGAAGGACGAGAACGGGCTGCGCTGGTCCTGGGACCCGGATGGCTGCTGCG
AGATCCGCAAGGTCGAGCCGCTGGCCAGGGCCCTGCTCCACTTCGATGCATCGATCACCGGCCGCAAGGGCTTCCAGTCG
AAGACCCGCGCAGGGCTTCCACGGTTCGAGATCGACCGTTCGGACGCGCAAGGACGGTTGAAGATCAACCCGCTCGCGTC
ATGGGACAAGACCATGCTCGAGGCCTATTTCGCAGAGCATGGCTTGCCGCCGCATCCGCTGGTCGCGCAGGGCTATCCCT
CGATCGGCTGCGCGCCCTGCACCAGCAAGGTTGCCCCCGGTGAAGACCCGCGCTCGGGCCGCTGGAAGGGCTGGGACAAG
ACCGAATGCGGCATCCATTCGCCCACCGACGACGAAGCCGCAGGCAAGAAGCCTGGCGACGAACTGCCCCCAGGATACGA
ACCGGTCTTCTGA

Upstream 100 bases:

>100_bases
TCGCGACCAGGCCGGAGGTCTACCAGAAGACCGTCGACGGGCGCCCGGCCATCTGGGCGAAGCGTCACCCGGCCTGAGCC
GGGATCGAGGAACGAAGCCA

Downstream 100 bases:

>100_bases
GGCAGCGCCCTGCCGCAGACGCGCGGTGGGGCAAGACGGCTGCAAGAAGGGCATCCGCTCGCGCTTTCCCGCCCATCCTG
GCTCTGCTAGGCCCCCTCCC

Product: phosphoadenosine phosphosulfate reductase

Products: NA

Alternate protein names: 3'-phosphoadenylylsulfate reductase; PAPS reductase, thioredoxin dependent; PAPS sulfotransferase; PAdoPS reductase [H]

Number of amino acids: Translated: 270; Mature: 270

Protein sequence:

>270_residues
MDSTVTRKIDLLDTAPRFTETDAIRLNNLFRGTDTHDMLRSVIRDGLAGDLAVVSSFGAESAVLLHLIAEVDPSVPVLFL
ETGKHFRETVAYRDELIGFLGMTNLQIIEPDAAVIAKKDENGLRWSWDPDGCCEIRKVEPLARALLHFDASITGRKGFQS
KTRAGLPRFEIDRSDAQGRLKINPLASWDKTMLEAYFAEHGLPPHPLVAQGYPSIGCAPCTSKVAPGEDPRSGRWKGWDK
TECGIHSPTDDEAAGKKPGDELPPGYEPVF

Sequences:

>Translated_270_residues
MDSTVTRKIDLLDTAPRFTETDAIRLNNLFRGTDTHDMLRSVIRDGLAGDLAVVSSFGAESAVLLHLIAEVDPSVPVLFL
ETGKHFRETVAYRDELIGFLGMTNLQIIEPDAAVIAKKDENGLRWSWDPDGCCEIRKVEPLARALLHFDASITGRKGFQS
KTRAGLPRFEIDRSDAQGRLKINPLASWDKTMLEAYFAEHGLPPHPLVAQGYPSIGCAPCTSKVAPGEDPRSGRWKGWDK
TECGIHSPTDDEAAGKKPGDELPPGYEPVF
>Mature_270_residues
MDSTVTRKIDLLDTAPRFTETDAIRLNNLFRGTDTHDMLRSVIRDGLAGDLAVVSSFGAESAVLLHLIAEVDPSVPVLFL
ETGKHFRETVAYRDELIGFLGMTNLQIIEPDAAVIAKKDENGLRWSWDPDGCCEIRKVEPLARALLHFDASITGRKGFQS
KTRAGLPRFEIDRSDAQGRLKINPLASWDKTMLEAYFAEHGLPPHPLVAQGYPSIGCAPCTSKVAPGEDPRSGRWKGWDK
TECGIHSPTDDEAAGKKPGDELPPGYEPVF

Specific function: Reduction of activated sulfate into sulfite [H]

COG id: COG0175

COG function: function code EH; 3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase and related enzymes

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PAPS reductase family. CysH subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789121, Length=207, Percent_Identity=35.7487922705314, Blast_Score=117, Evalue=8e-28,
Organism=Saccharomyces cerevisiae, GI6325425, Length=211, Percent_Identity=34.5971563981043, Blast_Score=105, Evalue=1e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004511
- InterPro:   IPR002500
- InterPro:   IPR014729 [H]

Pfam domain/function: PF01507 PAPS_reduct [H]

EC number: =1.8.4.8 [H]

Molecular weight: Translated: 29680; Mature: 29680

Theoretical pI: Translated: 5.22; Mature: 5.22

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDSTVTRKIDLLDTAPRFTETDAIRLNNLFRGTDTHDMLRSVIRDGLAGDLAVVSSFGAE
CCCCHHEEEEHHCCCCCCCCCCHHHEHHHHCCCCHHHHHHHHHHCCCCCHHHHHHHCCCH
SAVLLHLIAEVDPSVPVLFLETGKHFRETVAYRDELIGFLGMTNLQIIEPDAAVIAKKDE
HHHHHHHHHHCCCCCCEEEECCCHHHHHHHHHHHHHHHHHCCCCEEEECCCCEEEEECCC
NGLRWSWDPDGCCEIRKVEPLARALLHFDASITGRKGFQSKTRAGLPRFEIDRSDAQGRL
CCCEECCCCCCCEEHHHHHHHHHHHHHHCCCCCCCCCCCHHHHCCCCCEEECCCCCCCEE
KINPLASWDKTMLEAYFAEHGLPPHPLVAQGYPSIGCAPCTSKVAPGEDPRSGRWKGWDK
EECCCCHHHHHHHHHHHHHCCCCCCCCHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
TECGIHSPTDDEAAGKKPGDELPPGYEPVF
CCCCCCCCCCCHHCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MDSTVTRKIDLLDTAPRFTETDAIRLNNLFRGTDTHDMLRSVIRDGLAGDLAVVSSFGAE
CCCCHHEEEEHHCCCCCCCCCCHHHEHHHHCCCCHHHHHHHHHHCCCCCHHHHHHHCCCH
SAVLLHLIAEVDPSVPVLFLETGKHFRETVAYRDELIGFLGMTNLQIIEPDAAVIAKKDE
HHHHHHHHHHCCCCCCEEEECCCHHHHHHHHHHHHHHHHHCCCCEEEECCCCEEEEECCC
NGLRWSWDPDGCCEIRKVEPLARALLHFDASITGRKGFQSKTRAGLPRFEIDRSDAQGRL
CCCEECCCCCCCEEHHHHHHHHHHHHHHCCCCCCCCCCCHHHHCCCCCEEECCCCCCCEE
KINPLASWDKTMLEAYFAEHGLPPHPLVAQGYPSIGCAPCTSKVAPGEDPRSGRWKGWDK
EECCCCHHHHHHHHHHHHHCCCCCCCCHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
TECGIHSPTDDEAAGKKPGDELPPGYEPVF
CCCCCCCCCCCHHCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11214968 [H]