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The map label for this gene is sdcS [H]

Identifier: 87200574

GI number: 87200574

Start: 2763327

End: 2764727

Strand: Direct

Name: sdcS [H]

Synonym: Saro_2561

Alternate gene names: 87200574

Gene position: 2763327-2764727 (Clockwise)

Preceding gene: 87200573

Following gene: 87200575

Centisome position: 77.59

GC content: 67.95

Gene sequence:

>1401_bases
ATGGACGCGCGCAGGATCGGGCTGCTGGCCGGACCGCTGGGATTTGCCGCTACGCTGTTGCTGGCCCCGCCTGCGGGCAT
GCCGGACAACGCGTGGGCCGCGGCCGGGCTGGTGTGGTGGATGGCTGCCTGGTGGATGACCGAGGCGATGCCGCTTTCGG
CGACCGCGCTGCTGCCGTTCCTCGTTCTTCCGCTGACCGGCGTTGCCGATGCGAACAAGACCGCCGGCTCCTACTATTCG
CCGATCATGTTCCTGTTCGTGGGCGGCGCGTTTCTCGCGCTGGCCATCGAGCGCACCGGACTGCACCGGCGACTGGCCGT
CTTCATCATGGGACTGGCGGGAACGAAGCCGAGCCAGTTGCTGCTGGCCGTGATGGCCGCCACGGCGACGCTTTCCAGCT
TCATCTCGAACACTTCGACGGCTCTCATCATGATGCCGATGGCGCTGGCCATGCTGGCGGCAGGCGGAGTGCGCGAAGGC
GAGACGCGCGGCATGGCGGGCGCCCTGCCGATGGGCATTGCATTTGCCGCGAGCATCGGCGGGCTGGCGACGCTGATCGG
CACGCCGACCAACGCGATTGCTGCCGGCCTCATCGAGAAGTCGCTCGGCACCGAGATCACCTTCCTGCGCTGGGCGATGT
ACGGCGTACCCATCGTGCTCATCGCCGTGCCCCTGGCCGCGTGGATCATCGCCCGGGTGCAGAAGCTTGACGAAGACAGC
TTCGACCCCCTCGCCGCGCGAGAGGCCATCGGAAGCGCAACGGCATGGACGACGCCGGAAAGACGCCTTGTCCCGGTCGC
CCTGCTGGCCTTTCTCGCCTGGGTGGCGCAGCCCTGGCTCGAAGGCCTGTTCCCCAAGGGGGGCCTGACCGACGGGACCA
TCGCCGCCGCAGCAGGCCTCGTGCTGTTCTTCCTGCCTGACGGCACCGGGCGCCCCATGCTGACCTGGCCCGAGGCGAAC
CGGGCACCGTGGGACGTCGTGCTGATGTTCGGCGGCGGGCTGGCAATGGCGATGGGCATGACCGAATCCGGCCTGACGAA
ATGGATGGGCGAAATGCTGCTGCCGCTTGCCGGCGTACCGCTTCCGGTCGTGGCGCTCGTCCTGGTGGCATTCGTCATTC
TCGTGACGGAATTTGCCAGCAACATCGCCGCTGCCAGCGGGATCATGCCCGTGGTGGCGGCGCTCGTCGCCGCACTGGGG
GCCGATCCGATCATGCTCGCGCTGCCGGCGGCATTCGCGGCGACATGGGGATTCATGCTGCCAGCCGGCACCGGACCCAA
CGCCCTGGCATGGGCAACGGGGCACTGTTCGATGCGGTCGATGATAAAGGCCGGGTTCGCGCTGGACGTGGCCGGCGTGT
TCCTGCTGGTCGGGGTGGTCTGGACGGTTACTTCTCTCTGA

Upstream 100 bases:

>100_bases
GGCAAGACGGCTGCAAGAAGGGCATCCGCTCGCGCTTTCCCGCCCATCCTGGCTCTGCTAGGCCCCCTCCCGGGACATCG
GGGGGAGTGACGCAAGGGTG

Downstream 100 bases:

>100_bases
ACAGGCCCGGCGCACTAATACGTAATTCCCTCTTCACCGAACCGGCCTTTCCGGGTTAGACAATCTTCCAAGGGCCTCCG
GCTGAATCGCTGTTTTCATG

Product: anion transporter

Products: NA

Alternate protein names: Na(+)/dicarboxylate symporter [H]

Number of amino acids: Translated: 466; Mature: 466

Protein sequence:

>466_residues
MDARRIGLLAGPLGFAATLLLAPPAGMPDNAWAAAGLVWWMAAWWMTEAMPLSATALLPFLVLPLTGVADANKTAGSYYS
PIMFLFVGGAFLALAIERTGLHRRLAVFIMGLAGTKPSQLLLAVMAATATLSSFISNTSTALIMMPMALAMLAAGGVREG
ETRGMAGALPMGIAFAASIGGLATLIGTPTNAIAAGLIEKSLGTEITFLRWAMYGVPIVLIAVPLAAWIIARVQKLDEDS
FDPLAAREAIGSATAWTTPERRLVPVALLAFLAWVAQPWLEGLFPKGGLTDGTIAAAAGLVLFFLPDGTGRPMLTWPEAN
RAPWDVVLMFGGGLAMAMGMTESGLTKWMGEMLLPLAGVPLPVVALVLVAFVILVTEFASNIAAASGIMPVVAALVAALG
ADPIMLALPAAFAATWGFMLPAGTGPNALAWATGHCSMRSMIKAGFALDVAGVFLLVGVVWTVTSL

Sequences:

>Translated_466_residues
MDARRIGLLAGPLGFAATLLLAPPAGMPDNAWAAAGLVWWMAAWWMTEAMPLSATALLPFLVLPLTGVADANKTAGSYYS
PIMFLFVGGAFLALAIERTGLHRRLAVFIMGLAGTKPSQLLLAVMAATATLSSFISNTSTALIMMPMALAMLAAGGVREG
ETRGMAGALPMGIAFAASIGGLATLIGTPTNAIAAGLIEKSLGTEITFLRWAMYGVPIVLIAVPLAAWIIARVQKLDEDS
FDPLAAREAIGSATAWTTPERRLVPVALLAFLAWVAQPWLEGLFPKGGLTDGTIAAAAGLVLFFLPDGTGRPMLTWPEAN
RAPWDVVLMFGGGLAMAMGMTESGLTKWMGEMLLPLAGVPLPVVALVLVAFVILVTEFASNIAAASGIMPVVAALVAALG
ADPIMLALPAAFAATWGFMLPAGTGPNALAWATGHCSMRSMIKAGFALDVAGVFLLVGVVWTVTSL
>Mature_466_residues
MDARRIGLLAGPLGFAATLLLAPPAGMPDNAWAAAGLVWWMAAWWMTEAMPLSATALLPFLVLPLTGVADANKTAGSYYS
PIMFLFVGGAFLALAIERTGLHRRLAVFIMGLAGTKPSQLLLAVMAATATLSSFISNTSTALIMMPMALAMLAAGGVREG
ETRGMAGALPMGIAFAASIGGLATLIGTPTNAIAAGLIEKSLGTEITFLRWAMYGVPIVLIAVPLAAWIIARVQKLDEDS
FDPLAAREAIGSATAWTTPERRLVPVALLAFLAWVAQPWLEGLFPKGGLTDGTIAAAAGLVLFFLPDGTGRPMLTWPEAN
RAPWDVVLMFGGGLAMAMGMTESGLTKWMGEMLLPLAGVPLPVVALVLVAFVILVTEFASNIAAASGIMPVVAALVAALG
ADPIMLALPAAFAATWGFMLPAGTGPNALAWATGHCSMRSMIKAGFALDVAGVFLLVGVVWTVTSL

Specific function: Mediates the transport of dicarboxylates across the cytoplasmic membrane via a Na(+)-electrochemical gradient [H]

COG id: COG0471

COG function: function code P; Di- and tricarboxylate transporters

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the SLC13A transporter (TC 2.A.47) family. NADC subfamily [H]

Homologues:

Organism=Homo sapiens, GI31377715, Length=515, Percent_Identity=30.6796116504854, Blast_Score=210, Evalue=2e-54,
Organism=Homo sapiens, GI58761541, Length=515, Percent_Identity=30.0970873786408, Blast_Score=206, Evalue=4e-53,
Organism=Homo sapiens, GI301069349, Length=494, Percent_Identity=30.9716599190283, Blast_Score=202, Evalue=8e-52,
Organism=Homo sapiens, GI4506979, Length=510, Percent_Identity=29.0196078431373, Blast_Score=195, Evalue=9e-50,
Organism=Homo sapiens, GI29171306, Length=513, Percent_Identity=28.2651072124756, Blast_Score=192, Evalue=4e-49,
Organism=Homo sapiens, GI225637549, Length=571, Percent_Identity=26.2697022767075, Blast_Score=171, Evalue=9e-43,
Organism=Homo sapiens, GI225637552, Length=479, Percent_Identity=27.7661795407098, Blast_Score=162, Evalue=8e-40,
Organism=Homo sapiens, GI301069353, Length=464, Percent_Identity=28.448275862069, Blast_Score=159, Evalue=6e-39,
Organism=Homo sapiens, GI219802232, Length=454, Percent_Identity=27.5330396475771, Blast_Score=145, Evalue=6e-35,
Organism=Homo sapiens, GI31795546, Length=341, Percent_Identity=26.6862170087977, Blast_Score=143, Evalue=4e-34,
Organism=Homo sapiens, GI301069346, Length=192, Percent_Identity=38.0208333333333, Blast_Score=127, Evalue=3e-29,
Organism=Homo sapiens, GI19923838, Length=322, Percent_Identity=29.8136645962733, Blast_Score=121, Evalue=2e-27,
Organism=Escherichia coli, GI1786829, Length=486, Percent_Identity=23.8683127572016, Blast_Score=71, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI71988385, Length=456, Percent_Identity=32.0175438596491, Blast_Score=205, Evalue=3e-53,
Organism=Caenorhabditis elegans, GI32565804, Length=442, Percent_Identity=31.9004524886878, Blast_Score=194, Evalue=8e-50,
Organism=Caenorhabditis elegans, GI17551790, Length=491, Percent_Identity=25.050916496945, Blast_Score=171, Evalue=7e-43,
Organism=Caenorhabditis elegans, GI71989118, Length=486, Percent_Identity=26.1316872427983, Blast_Score=171, Evalue=1e-42,
Organism=Caenorhabditis elegans, GI32564681, Length=523, Percent_Identity=24.8565965583174, Blast_Score=167, Evalue=1e-41,
Organism=Saccharomyces cerevisiae, GI6324340, Length=405, Percent_Identity=24.1975308641975, Blast_Score=86, Evalue=1e-17,
Organism=Saccharomyces cerevisiae, GI6319885, Length=419, Percent_Identity=26.7303102625298, Blast_Score=85, Evalue=2e-17,
Organism=Saccharomyces cerevisiae, GI6322263, Length=423, Percent_Identity=26.9503546099291, Blast_Score=81, Evalue=3e-16,
Organism=Drosophila melanogaster, GI281362116, Length=465, Percent_Identity=29.0322580645161, Blast_Score=156, Evalue=3e-38,
Organism=Drosophila melanogaster, GI281362114, Length=465, Percent_Identity=28.8172043010753, Blast_Score=149, Evalue=4e-36,
Organism=Drosophila melanogaster, GI281362112, Length=465, Percent_Identity=28.8172043010753, Blast_Score=149, Evalue=4e-36,
Organism=Drosophila melanogaster, GI281366409, Length=472, Percent_Identity=27.1186440677966, Blast_Score=147, Evalue=1e-35,
Organism=Drosophila melanogaster, GI17737623, Length=472, Percent_Identity=27.1186440677966, Blast_Score=147, Evalue=1e-35,
Organism=Drosophila melanogaster, GI24666468, Length=472, Percent_Identity=27.1186440677966, Blast_Score=147, Evalue=1e-35,
Organism=Drosophila melanogaster, GI45551633, Length=472, Percent_Identity=27.1186440677966, Blast_Score=147, Evalue=1e-35,
Organism=Drosophila melanogaster, GI78706796, Length=496, Percent_Identity=26.008064516129, Blast_Score=109, Evalue=3e-24,
Organism=Drosophila melanogaster, GI78706798, Length=496, Percent_Identity=26.008064516129, Blast_Score=109, Evalue=3e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001898 [H]

Pfam domain/function: PF00939 Na_sulph_symp [H]

EC number: NA

Molecular weight: Translated: 48186; Mature: 48186

Theoretical pI: Translated: 5.35; Mature: 5.35

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
5.8 %Met     (Translated Protein)
6.0 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
5.8 %Met     (Mature Protein)
6.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDARRIGLLAGPLGFAATLLLAPPAGMPDNAWAAAGLVWWMAAWWMTEAMPLSATALLPF
CCCCCEEHHCCCHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
LVLPLTGVADANKTAGSYYSPIMFLFVGGAFLALAIERTGLHRRLAVFIMGLAGTKPSQL
HHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHCCCCCHHHH
LLAVMAATATLSSFISNTSTALIMMPMALAMLAAGGVREGETRGMAGALPMGIAFAASIG
HHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHH
GLATLIGTPTNAIAAGLIEKSLGTEITFLRWAMYGVPIVLIAVPLAAWIIARVQKLDEDS
HHHHHHCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
FDPLAAREAIGSATAWTTPERRLVPVALLAFLAWVAQPWLEGLFPKGGLTDGTIAAAAGL
CCHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHCE
VLFFLPDGTGRPMLTWPEANRAPWDVVLMFGGGLAMAMGMTESGLTKWMGEMLLPLAGVP
EEEEECCCCCCCEEECCCCCCCCCEEEEEECCCHHHHHCCCHHHHHHHHHHHHHHHCCCC
LPVVALVLVAFVILVTEFASNIAAASGIMPVVAALVAALGADPIMLALPAAFAATWGFML
HHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHC
PAGTGPNALAWATGHCSMRSMIKAGFALDVAGVFLLVGVVWTVTSL
CCCCCCCCEEEECCCHHHHHHHHHCHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MDARRIGLLAGPLGFAATLLLAPPAGMPDNAWAAAGLVWWMAAWWMTEAMPLSATALLPF
CCCCCEEHHCCCHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
LVLPLTGVADANKTAGSYYSPIMFLFVGGAFLALAIERTGLHRRLAVFIMGLAGTKPSQL
HHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHCCCCCHHHH
LLAVMAATATLSSFISNTSTALIMMPMALAMLAAGGVREGETRGMAGALPMGIAFAASIG
HHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHH
GLATLIGTPTNAIAAGLIEKSLGTEITFLRWAMYGVPIVLIAVPLAAWIIARVQKLDEDS
HHHHHHCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
FDPLAAREAIGSATAWTTPERRLVPVALLAFLAWVAQPWLEGLFPKGGLTDGTIAAAAGL
CCHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHCE
VLFFLPDGTGRPMLTWPEANRAPWDVVLMFGGGLAMAMGMTESGLTKWMGEMLLPLAGVP
EEEEECCCCCCCEEECCCCCCCCCEEEEEECCCHHHHHCCCHHHHHHHHHHHHHHHCCCC
LPVVALVLVAFVILVTEFASNIAAASGIMPVVAALVAALGADPIMLALPAAFAATWGFML
HHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHC
PAGTGPNALAWATGHCSMRSMIKAGFALDVAGVFLLVGVVWTVTSL
CCCCCCCCEEEECCCHHHHHHHHHCHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA