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The map label for this gene is 86606444

Identifier: 86606444

GI number: 86606444

Start: 1790928

End: 1792973

Strand: Reverse

Name: 86606444

Synonym: CYA_1791

Alternate gene names: NA

Gene position: 1792973-1790928 (Counterclockwise)

Preceding gene: 86606445

Following gene: 86606443

Centisome position: 61.14

GC content: 67.2

Gene sequence:

>2046_bases
ATGGCCAATGCCAGTAGCGCGCAAGGCAAGCAACAGGATGGGAGGCAGGGGGGCCTGGTCCGCCTGGGGATCGACGTGGG
AGGCACCTTCACGGATCTGGTGCTCCTCCAGGAAGGCCAGATCCGGACAGCCAAGGTGCTCTCCACCCCCAGCCCAGAAG
CGGGGGTCTTTGGCGCCCTGGACAAGCTGGGCCCAGTTGAGGTGGACGTGTTCTGCCACGGCATGACGGTGGCCACCAAC
GCCCTCTTGGAGCGCAAGGGATCCCCCACCCTGTTTCTGACCACGGCGGGCTTCCGGGATGTGCTGGCCATTGGTCGCCA
AAACCGCCCTTCCCTTTACGACCTCACCCAGCCCAAGCCAGAGCCGGTGGTGCCCCGCCACCACTGCCTGGAGGTGAAGG
AGCGCTGCAGCGCCGGCGGCGTGGTCGAGCCGCTGACGGAAGAGGAAATCCAGCGCGTCCTCCGGGAAGTGGGCGAGCGG
GTAGAGCGGGATGGGATCCGTGCCGTGGGGGTGGGATTCTTGTTTTCTTTCCTCTACCCGGAGCACGAGCAGCGCCTGGG
GGCGGCCCTGAGAGAGGCTTTCCCCGACTTGCATGTTTCCCTCTCCTGCGAAGTGGCGCCGGAGTTTCGGGAATACGAGC
GCTTTAGCACCACGGCCATTGATGCCTACCTCAGCCCGGTGCTGGCGGGCTACCTGCACCGCTTGGCGCAGGGCTGCCGG
CAGCGAGGGATCCCCGAACCCCTGATCATGCAATCCTCCGGCGGCGTCACTTCCATTGCCCAGGCAGCGGCTCATGCCTC
GGTGGCGCTGCTTTCGGGGCCAGCGGGCGGCGTTTACGGGGCGGCCTACCTGGGCTGGCTGAGCGGCTATTCCCATCTGC
TCAGCTTCGATATGGGGGGAACCAGTACCGATGTGGCCCTCATTCAAGACGGCCTCCCTCAGGTTACCCCGTCAGCGGTG
GTGTGCGGCCTGCCGGTGCAACAGCCCCAGATCGACATCCATACCGTCAGCGCCGGGGGCGGATCCCTGGCCTCGCTGTT
GCCGGGCGGGGGGCTGCAGGTGGGGCCGGAAAGTGCCGGCTCCAACCCTGGGCCGGCCTGCTACGGTCGGGGGGGAACGG
CTCCCACGGTAACCGATGCCAACCTCTGGCTGGGCTACCTGCCGGATGGGGGCTGGCTGGGGGATGCCGTTTGCCTACGG
CGGGACTTGGCCGGCCAGGCCATCGGAACGCTGGCGGAGCCCTTGGGTTTGACTTTGGAGGAGACGGCTGTTGGCATTCG
CACCCTGGCCAATGTGGCCATGGCGCGGGCTTTGCGGGTCATCAGCGTGGAGCGGGGCTTGGATCCTGCCGATTTTGCCC
TGTTGGCCTTTGGCGGAGCCGGGCCCATGCACGCCTGTGCCCTGGCGGAAGAGCTGGGGATCCGCCGCGTCCTCGTCCCA
GCCTTTGCCGGTGTCCTCTCGGCTCTGGGTATGGCTTTGGCCGATCTGCGGCGGGACTACCGGCGGGCCATCCTGCAGCC
GCTGCAACAGTTGGAGGGGGAAGGGGGAGGATCCCTTTTGGCCCAGTGGGCGGCGCCCCTCATCCGCCAGGCGCAAGCCG
ACCTGCAGGAGCCGGGGCTCTCCTTCAGCCTCGACCTGCGCTACCGCGGCCAGTCTTTTGAGCTGGAGATCCCGGCCCAG
TTGTCGGATCCGGTTTCTCTCTTGGAGCAGCGGTTTCACCAGGCCCACCGCCAGCGCTACGGCTGGCAGGATCCCGACCA
AGAGGTGGAGGTGATCCAGCTGCGTCTGCGGGCGGTACAAGCTTTGCCCCCTGTGCCTTTAAAGGCGCCGCCCCCCCTGC
CAGGGGATCCCTTCAAGGGGGAGCGCCAGGCCTGGACGGGCGGCCGGATGCGACCGGTCCCAGTCTACGATCGGCGGCGC
ATGGGGGTGGGGTTTCAACTGGGCGGGCCAGCGATTGTGGAGATGCCGGAGGCTACCGTGGTGATCGAAGCCGGTTGGAC
GGGCAATATCGACGCCGTGGGAACCCTAATCCTGAGCTGCGGGTGA

Upstream 100 bases:

>100_bases
CTTTTGCAGCAGGAGCAACCCCTGGAAAGCAAGTCGGAAGAGGTGCCCCGGCCTCGTCTCTAGCGAGGGGTTGAGGCCTG
CCCAAGGGTCTTATCGAGCC

Downstream 100 bases:

>100_bases
TTCCGTTGCCAGGTGCGGCCCTCGGGAACCCTTCCTCAGCTTGGTTGCCAGCAGTTTTGCAAGGTTTTGAGGTTTTCTCT
AAATTGGCAGGGCCCAGGTT

Product: hydantoin utilization protein A

Products: ADP; phosphate; N-carbamoylsarcosine

Alternate protein names: NA

Number of amino acids: Translated: 681; Mature: 680

Protein sequence:

>681_residues
MANASSAQGKQQDGRQGGLVRLGIDVGGTFTDLVLLQEGQIRTAKVLSTPSPEAGVFGALDKLGPVEVDVFCHGMTVATN
ALLERKGSPTLFLTTAGFRDVLAIGRQNRPSLYDLTQPKPEPVVPRHHCLEVKERCSAGGVVEPLTEEEIQRVLREVGER
VERDGIRAVGVGFLFSFLYPEHEQRLGAALREAFPDLHVSLSCEVAPEFREYERFSTTAIDAYLSPVLAGYLHRLAQGCR
QRGIPEPLIMQSSGGVTSIAQAAAHASVALLSGPAGGVYGAAYLGWLSGYSHLLSFDMGGTSTDVALIQDGLPQVTPSAV
VCGLPVQQPQIDIHTVSAGGGSLASLLPGGGLQVGPESAGSNPGPACYGRGGTAPTVTDANLWLGYLPDGGWLGDAVCLR
RDLAGQAIGTLAEPLGLTLEETAVGIRTLANVAMARALRVISVERGLDPADFALLAFGGAGPMHACALAEELGIRRVLVP
AFAGVLSALGMALADLRRDYRRAILQPLQQLEGEGGGSLLAQWAAPLIRQAQADLQEPGLSFSLDLRYRGQSFELEIPAQ
LSDPVSLLEQRFHQAHRQRYGWQDPDQEVEVIQLRLRAVQALPPVPLKAPPPLPGDPFKGERQAWTGGRMRPVPVYDRRR
MGVGFQLGGPAIVEMPEATVVIEAGWTGNIDAVGTLILSCG

Sequences:

>Translated_681_residues
MANASSAQGKQQDGRQGGLVRLGIDVGGTFTDLVLLQEGQIRTAKVLSTPSPEAGVFGALDKLGPVEVDVFCHGMTVATN
ALLERKGSPTLFLTTAGFRDVLAIGRQNRPSLYDLTQPKPEPVVPRHHCLEVKERCSAGGVVEPLTEEEIQRVLREVGER
VERDGIRAVGVGFLFSFLYPEHEQRLGAALREAFPDLHVSLSCEVAPEFREYERFSTTAIDAYLSPVLAGYLHRLAQGCR
QRGIPEPLIMQSSGGVTSIAQAAAHASVALLSGPAGGVYGAAYLGWLSGYSHLLSFDMGGTSTDVALIQDGLPQVTPSAV
VCGLPVQQPQIDIHTVSAGGGSLASLLPGGGLQVGPESAGSNPGPACYGRGGTAPTVTDANLWLGYLPDGGWLGDAVCLR
RDLAGQAIGTLAEPLGLTLEETAVGIRTLANVAMARALRVISVERGLDPADFALLAFGGAGPMHACALAEELGIRRVLVP
AFAGVLSALGMALADLRRDYRRAILQPLQQLEGEGGGSLLAQWAAPLIRQAQADLQEPGLSFSLDLRYRGQSFELEIPAQ
LSDPVSLLEQRFHQAHRQRYGWQDPDQEVEVIQLRLRAVQALPPVPLKAPPPLPGDPFKGERQAWTGGRMRPVPVYDRRR
MGVGFQLGGPAIVEMPEATVVIEAGWTGNIDAVGTLILSCG
>Mature_680_residues
ANASSAQGKQQDGRQGGLVRLGIDVGGTFTDLVLLQEGQIRTAKVLSTPSPEAGVFGALDKLGPVEVDVFCHGMTVATNA
LLERKGSPTLFLTTAGFRDVLAIGRQNRPSLYDLTQPKPEPVVPRHHCLEVKERCSAGGVVEPLTEEEIQRVLREVGERV
ERDGIRAVGVGFLFSFLYPEHEQRLGAALREAFPDLHVSLSCEVAPEFREYERFSTTAIDAYLSPVLAGYLHRLAQGCRQ
RGIPEPLIMQSSGGVTSIAQAAAHASVALLSGPAGGVYGAAYLGWLSGYSHLLSFDMGGTSTDVALIQDGLPQVTPSAVV
CGLPVQQPQIDIHTVSAGGGSLASLLPGGGLQVGPESAGSNPGPACYGRGGTAPTVTDANLWLGYLPDGGWLGDAVCLRR
DLAGQAIGTLAEPLGLTLEETAVGIRTLANVAMARALRVISVERGLDPADFALLAFGGAGPMHACALAEELGIRRVLVPA
FAGVLSALGMALADLRRDYRRAILQPLQQLEGEGGGSLLAQWAAPLIRQAQADLQEPGLSFSLDLRYRGQSFELEIPAQL
SDPVSLLEQRFHQAHRQRYGWQDPDQEVEVIQLRLRAVQALPPVPLKAPPPLPGDPFKGERQAWTGGRMRPVPVYDRRRM
GVGFQLGGPAIVEMPEATVVIEAGWTGNIDAVGTLILSCG

Specific function: Unknown

COG id: COG0145

COG function: function code EQ; N-methylhydantoinase A/acetone carboxylase, beta subunit

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the oxoprolinase family [H]

Homologues:

Organism=Homo sapiens, GI48314820, Length=730, Percent_Identity=34.1095890410959, Blast_Score=250, Evalue=3e-66,
Organism=Caenorhabditis elegans, GI133901900, Length=719, Percent_Identity=29.9026425591099, Blast_Score=233, Evalue=3e-61,
Organism=Saccharomyces cerevisiae, GI6322634, Length=640, Percent_Identity=33.59375, Blast_Score=264, Evalue=4e-71,
Organism=Drosophila melanogaster, GI45550492, Length=741, Percent_Identity=33.7381916329285, Blast_Score=290, Evalue=2e-78,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008040
- InterPro:   IPR002821 [H]

Pfam domain/function: PF05378 Hydant_A_N; PF01968 Hydantoinase_A [H]

EC number: 3.5.2.14

Molecular weight: Translated: 72226; Mature: 72094

Theoretical pI: Translated: 5.29; Mature: 5.29

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MANASSAQGKQQDGRQGGLVRLGIDVGGTFTDLVLLQEGQIRTAKVLSTPSPEAGVFGAL
CCCCCCCCCCCCCCCCCCEEEEEECCCCCCEEEEEEECCCCEEEEEECCCCCCCCHHHHH
DKLGPVEVDVFCHGMTVATNALLERKGSPTLFLTTAGFRDVLAIGRQNRPSLYDLTQPKP
HCCCCEEEEEEECCHHHHHHHHHHCCCCCEEEEEECCHHHHHHHCCCCCCCCEECCCCCC
EPVVPRHHCLEVKERCSAGGVVEPLTEEEIQRVLREVGERVERDGIRAVGVGFLFSFLYP
CCCCCHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCC
EHEQRLGAALREAFPDLHVSLSCEVAPEFREYERFSTTAIDAYLSPVLAGYLHRLAQGCR
HHHHHHHHHHHHHCCCCEEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QRGIPEPLIMQSSGGVTSIAQAAAHASVALLSGPAGGVYGAAYLGWLSGYSHLLSFDMGG
HCCCCCCEEEECCCCHHHHHHHHHHHEEEEEECCCCCHHHHHHHHHHHHHHHHHEECCCC
TSTDVALIQDGLPQVTPSAVVCGLPVQQPQIDIHTVSAGGGSLASLLPGGGLQVGPESAG
CCCCHHHHHCCCCCCCCCCEEECCCCCCCCEEEEEECCCCCCHHHHCCCCCCEECCCCCC
SNPGPACYGRGGTAPTVTDANLWLGYLPDGGWLGDAVCLRRDLAGQAIGTLAEPLGLTLE
CCCCCCCCCCCCCCCCEECCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHH
ETAVGIRTLANVAMARALRVISVERGLDPADFALLAFGGAGPMHACALAEELGIRRVLVP
HHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHEEEEEECCCCHHHHHHHHHHHCCHHHHHH
AFAGVLSALGMALADLRRDYRRAILQPLQQLEGEGGGSLLAQWAAPLIRQAQADLQEPGL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCC
SFSLDLRYRGQSFELEIPAQLSDPVSLLEQRFHQAHRQRYGWQDPDQEVEVIQLRLRAVQ
EEEEEEEECCCEEEEEECCCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHH
ALPPVPLKAPPPLPGDPFKGERQAWTGGRMRPVPVYDRRRMGVGFQLGGPAIVEMPEATV
HCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEECCCCEEEECCCEEE
VIEAGWTGNIDAVGTLILSCG
EEECCCCCCHHHHHHHHEECC
>Mature Secondary Structure 
ANASSAQGKQQDGRQGGLVRLGIDVGGTFTDLVLLQEGQIRTAKVLSTPSPEAGVFGAL
CCCCCCCCCCCCCCCCCEEEEEECCCCCCEEEEEEECCCCEEEEEECCCCCCCCHHHHH
DKLGPVEVDVFCHGMTVATNALLERKGSPTLFLTTAGFRDVLAIGRQNRPSLYDLTQPKP
HCCCCEEEEEEECCHHHHHHHHHHCCCCCEEEEEECCHHHHHHHCCCCCCCCEECCCCCC
EPVVPRHHCLEVKERCSAGGVVEPLTEEEIQRVLREVGERVERDGIRAVGVGFLFSFLYP
CCCCCHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCC
EHEQRLGAALREAFPDLHVSLSCEVAPEFREYERFSTTAIDAYLSPVLAGYLHRLAQGCR
HHHHHHHHHHHHHCCCCEEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QRGIPEPLIMQSSGGVTSIAQAAAHASVALLSGPAGGVYGAAYLGWLSGYSHLLSFDMGG
HCCCCCCEEEECCCCHHHHHHHHHHHEEEEEECCCCCHHHHHHHHHHHHHHHHHEECCCC
TSTDVALIQDGLPQVTPSAVVCGLPVQQPQIDIHTVSAGGGSLASLLPGGGLQVGPESAG
CCCCHHHHHCCCCCCCCCCEEECCCCCCCCEEEEEECCCCCCHHHHCCCCCCEECCCCCC
SNPGPACYGRGGTAPTVTDANLWLGYLPDGGWLGDAVCLRRDLAGQAIGTLAEPLGLTLE
CCCCCCCCCCCCCCCCEECCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHH
ETAVGIRTLANVAMARALRVISVERGLDPADFALLAFGGAGPMHACALAEELGIRRVLVP
HHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHEEEEEECCCCHHHHHHHHHHHCCHHHHHH
AFAGVLSALGMALADLRRDYRRAILQPLQQLEGEGGGSLLAQWAAPLIRQAQADLQEPGL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCC
SFSLDLRYRGQSFELEIPAQLSDPVSLLEQRFHQAHRQRYGWQDPDQEVEVIQLRLRAVQ
EEEEEEEECCCEEEEEECCCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHH
ALPPVPLKAPPPLPGDPFKGERQAWTGGRMRPVPVYDRRRMGVGFQLGGPAIVEMPEATV
HCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEECCCCEEEECCCEEE
VIEAGWTGNIDAVGTLILSCG
EEECCCCCCHHHHHHHHEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; N-methylimidazolidine-2,4-dione; H2O

Specific reaction: ATP + N-methylimidazolidine-2,4-dione + 2 H2O = ADP + phosphate + N-carbamoylsarcosine

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]