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The map label for this gene is yitJ [H]

Identifier: 86605986

GI number: 86605986

Start: 1314340

End: 1315251

Strand: Reverse

Name: yitJ [H]

Synonym: CYA_1304

Alternate gene names: 86605986

Gene position: 1315251-1314340 (Counterclockwise)

Preceding gene: 86605987

Following gene: 86605979

Centisome position: 44.85

GC content: 66.23

Gene sequence:

>912_bases
GTGGCCCTGACCTGCCCACCACCGTCGCGCTTTGCCCAAGCCATCCAGCGGGGGGAATTTTTGCTCACGGCTGAGATCAC
CCCCCCCAAGGGATCCGACACCAGCACCCTGCTCTCTCTGGCCCAGCAGCTCAAGGGCCGGGTGCATGCCGTCAACATCA
CGGACTCCAACCGCGCCATGGCCCGCATGAGCCCCCTGGCCGCCTCGCTGCTGTTGCAGCAGGCGGGCGTTGAACCCATC
CTGCAGCTGGCCTGCCGGGATCGCAACCGCCTGGCTCTGCAGGGGGATCTGTTGGGGGCCTCAGCGCTCGGCCTGCGCAA
CGTGCTGGCCCTCACCGGGGATCCCATCCAGGTGGGGGATTGCCCCGATGCCCGCCCAGTCTTTGACCTGGAATCGGTGC
GTCTGCTGCAGCTTATCCAACGCCTCAACAACGGCCTCGACTGCAACGGCAAGCCCCTCCCCGACGGCGGCACCTGTCTG
TTCCCGGGGGCAGCCGTAGAGCCGCAATCCCCCAGCTTTTCCGGCCTGGAGCGGCGCTTCCACCGCAAGCTGGAGAACGG
AGCCCAGTTTTTCCAAAGCCAGATGGTGACCGACTTCGAGCAACTGGAGCGCTTCATGGACAAGCTGGGCCGCCCCGCCG
GCAAGCCCATCCTGGCGGGCATCTTCCTGCTCAAATCCGCCAAAAACGCCCTCTTCATCAACCGCAACTTGCCGGGGGTG
CAGATCCCGGACGCCATTATCCAGCGGCTGGCCGATGCCCCCGATCCCCTCGAAGAAGGGATCCGCATTGCTGCCGAACA
GGTGCGCCAGGCCCGCCAGATCTGTCACGGCGTGCACCTGATGGCCGTCAAGGCCGAACACCTCATCCCGCACATCCTGG
ACGAGGCCGGGATCCCGCCCCTGAGCAGCTAG

Upstream 100 bases:

>100_bases
TCGCCCAAGCCCTGAGAAAAGCGCTTTGGCTGGAAAAACCCTCCCAAAACAGCGGATAATAGGCCAACCCACTGCTTTTT
CTTTCGGTCTTCCCAGAATT

Downstream 100 bases:

>100_bases
CTCAACACCTGCTCCAAGCCGTAGACCAGCCCCTTGAGCTGCAGCACCTTGCGAATGCCCAGGATCACTCCCGGCATGAA
GGCCATCCGATCCGTGATGT

Product: methylenetetrahydrofolate reductase family protein

Products: NA

Alternate protein names: Homocysteine S-methyltransferase; S-methylmethionine:homocysteine methyltransferase; 5,10-methylenetetrahydrofolate reductase [H]

Number of amino acids: Translated: 303; Mature: 302

Protein sequence:

>303_residues
MALTCPPPSRFAQAIQRGEFLLTAEITPPKGSDTSTLLSLAQQLKGRVHAVNITDSNRAMARMSPLAASLLLQQAGVEPI
LQLACRDRNRLALQGDLLGASALGLRNVLALTGDPIQVGDCPDARPVFDLESVRLLQLIQRLNNGLDCNGKPLPDGGTCL
FPGAAVEPQSPSFSGLERRFHRKLENGAQFFQSQMVTDFEQLERFMDKLGRPAGKPILAGIFLLKSAKNALFINRNLPGV
QIPDAIIQRLADAPDPLEEGIRIAAEQVRQARQICHGVHLMAVKAEHLIPHILDEAGIPPLSS

Sequences:

>Translated_303_residues
MALTCPPPSRFAQAIQRGEFLLTAEITPPKGSDTSTLLSLAQQLKGRVHAVNITDSNRAMARMSPLAASLLLQQAGVEPI
LQLACRDRNRLALQGDLLGASALGLRNVLALTGDPIQVGDCPDARPVFDLESVRLLQLIQRLNNGLDCNGKPLPDGGTCL
FPGAAVEPQSPSFSGLERRFHRKLENGAQFFQSQMVTDFEQLERFMDKLGRPAGKPILAGIFLLKSAKNALFINRNLPGV
QIPDAIIQRLADAPDPLEEGIRIAAEQVRQARQICHGVHLMAVKAEHLIPHILDEAGIPPLSS
>Mature_302_residues
ALTCPPPSRFAQAIQRGEFLLTAEITPPKGSDTSTLLSLAQQLKGRVHAVNITDSNRAMARMSPLAASLLLQQAGVEPIL
QLACRDRNRLALQGDLLGASALGLRNVLALTGDPIQVGDCPDARPVFDLESVRLLQLIQRLNNGLDCNGKPLPDGGTCLF
PGAAVEPQSPSFSGLERRFHRKLENGAQFFQSQMVTDFEQLERFMDKLGRPAGKPILAGIFLLKSAKNALFINRNLPGVQ
IPDAIIQRLADAPDPLEEGIRIAAEQVRQARQICHGVHLMAVKAEHLIPHILDEAGIPPLSS

Specific function: Unknown

COG id: COG0685

COG function: function code E; 5,10-methylenetetrahydrofolate reductase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 Hcy-binding domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003171
- InterPro:   IPR003726 [H]

Pfam domain/function: PF02219 MTHFR; PF02574 S-methyl_trans [H]

EC number: =2.1.1.10; =1.5.1.20 [H]

Molecular weight: Translated: 32794; Mature: 32663

Theoretical pI: Translated: 7.85; Mature: 7.85

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MALTCPPPSRFAQAIQRGEFLLTAEITPPKGSDTSTLLSLAQQLKGRVHAVNITDSNRAM
CCCCCCCHHHHHHHHHCCCEEEEEEECCCCCCCHHHHHHHHHHHCCCEEEEEECCCCHHH
ARMSPLAASLLLQQAGVEPILQLACRDRNRLALQGDLLGASALGLRNVLALTGDPIQVGD
HHHHHHHHHHHHHHHCHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHHHHCCCCEEECC
CPDARPVFDLESVRLLQLIQRLNNGLDCNGKPLPDGGTCLFPGAAVEPQSPSFSGLERRF
CCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEECCCCCCCCCCCCHHHHHHHH
HRKLENGAQFFQSQMVTDFEQLERFMDKLGRPAGKPILAGIFLLKSAKNALFINRNLPGV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCEEEEECCCCCC
QIPDAIIQRLADAPDPLEEGIRIAAEQVRQARQICHGVHLMAVKAEHLIPHILDEAGIPP
CCCHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHEEHHHHHHHHHHHHHCCCCC
LSS
CCC
>Mature Secondary Structure 
ALTCPPPSRFAQAIQRGEFLLTAEITPPKGSDTSTLLSLAQQLKGRVHAVNITDSNRAM
CCCCCCHHHHHHHHHCCCEEEEEEECCCCCCCHHHHHHHHHHHCCCEEEEEECCCCHHH
ARMSPLAASLLLQQAGVEPILQLACRDRNRLALQGDLLGASALGLRNVLALTGDPIQVGD
HHHHHHHHHHHHHHHCHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHHHHCCCCEEECC
CPDARPVFDLESVRLLQLIQRLNNGLDCNGKPLPDGGTCLFPGAAVEPQSPSFSGLERRF
CCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEECCCCCCCCCCCCHHHHHHHH
HRKLENGAQFFQSQMVTDFEQLERFMDKLGRPAGKPILAGIFLLKSAKNALFINRNLPGV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCEEEEECCCCCC
QIPDAIIQRLADAPDPLEEGIRIAAEQVRQARQICHGVHLMAVKAEHLIPHILDEAGIPP
CCCHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHEEHHHHHHHHHHHHHCCCCC
LSS
CCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9353932; 9384377 [H]