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The map label for this gene is icd [H]

Identifier: 78189373

GI number: 78189373

Start: 1877389

End: 1879614

Strand: Reverse

Name: icd [H]

Synonym: Cag_1410

Alternate gene names: 78189373

Gene position: 1879614-1877389 (Counterclockwise)

Preceding gene: 78189374

Following gene: 78189372

Centisome position: 73.08

GC content: 45.06

Gene sequence:

>2226_bases
ATGGCACAAAACGCAACTATTATTTACACCAAAATTGATGAAGCGCCAGCGCTTGCTACGTATTCGCTGTTGCCTATTCT
GCAAGCTTATTTTAAGGGCACGGGTGTAACTATTGAATCGAGCGATATTTCACTCGCTGGTAGAATTATTGCCAACTTTC
CAGAAAATCTTACTGAAAGCCAGCGCATCCCCGATAACTTGAGTGCGTTAGGCCAACTTGCTTTAACTCCTGAAGCGAAT
ATTATTAAGCTGCCAAACATTAGCGCTTCAATTCCTCAGCTTCAAGCGGCTATTAAAGAGCTGCAAGAGCACGGCTATAA
TATTCCCAATTATCCTGAAGCGCCAGCAAACGACGCAGAAAAAGAGTTGCAAGTTCGTTTTGCAAAAGTGCTTGGTAGTG
CCGTAAACCCTGTACTTCGCGAAGGTAACTCCGACCGTCGTGCACCGCTTTCGGTTAAAAATTATGCAAAAAAGAATCCC
CATAAAATGTCGGCATGGAGCGCTGATTCAGCTTCTCATATTGCTCATATGGAGGGTGGCGACTTTTATGGTAGCGAAAA
ATCGGTTACTGTGGCTGATGCTACCAATGTAAAAATTGAGTTTGTAGGTAATGATGGCAGCAGCAAGGTTTTGAAAGAGA
AAACGGCGTTGCTTGCTGGTGAAGTTATTGATACGTCGGTTATGAACGTTCGTTCACTCCGAGCATTTTTTGACCAGCAA
ATTACCGATGCTAAAGAAAATGGCTTGCTTTTGTCGCTACACTTAAAAGCCACCATGATGAAGATTTCGGATCCCATCAT
GTTTGGTCATGCTGTTACTGTTTATTATAAGGATGTGTTTGAAAAACATGCGGCTACTATTGCAGAGCTTGGTGTGAATG
TCAATAACGGTCTTGGCGACTTGTATGCAAAGATTGAGAAGTTGCCTGCCGATAAAAAAGCTGCAATTGAGGCTGATATT
CAAGCGGTGTATGCAAATCGTCCCCCGCTTGCTATGGTTGATTCCGATAAAGGAATTACCAACCTCCACGTTCCAAACGA
TATTATTGTTGATGCTTCCATGCCGGTTGTTATTCGTGATGGTGGCAAAATGTGGGGACCTGATGGCAAATTGCACGACA
CTAAAGCAATGGTGCCTGATCGTTGCTATGCAACCATGTATCAAGCAATGGTTGAGGATTGCAAAAAGAATGGAGCATTT
AACCCATCAACCATTGGCAGCGTGCCTAACGTTGGTTTAATGGCTCAAAAAGCTGAAGAGTACGGTTCGCACGATAAAAC
CTTTACCGCTCCAGCAAACGGTGTGATTCGCGTGGTGGATGCTTCGGGCAAAACTCTGCTTGAGCAGAATGTTGAAACGG
GCGACATTTTTAGAATGTGCCAAACCAAAGATGCTCCAATTCGTGATTGGGTAAAACTTGCCGTTAATCGTGCACGCATT
ACGGGTGCGCCTGCTATTTTCTGGCTCGACAGCAACCGTGCTCACGATGCTCAAATTATCAACAAGGTAAACGAGTACCT
CAAAGAGCACGATACCAACGGTCTTGATATTCGCATTATGACGCCAGTGGATGCAATGCGCTTTTCGCTTGAGCGCTTCC
GTGCTGGAGAGGATACCATTTCGGTTACGGGTAACGTGCTTCGCGACTACCTCACCGACCTCTTCCCAATTATTGAGCTT
GGCACCAGTGCAAAAATGCTCTCAATTGTGCCATTGATGAATGGTGGTGGATTGTTTGAAACCGGTGCAGGTGGATCTGC
TCCAAAACATGTGCAGCAGTTCCAAAAAGAGGGATACCTCCGTTGGGATTCACTTGGTGAGTTCTCAGCGCTTGCCGCTT
CGCTTGATCACCTTTCTCGTGTGTTCAACAATCCAAAAGCAGCAGTTCTTGCTGAAACATTGGATGAGGCTATTGGCAAG
TTCCTTGATACCAACAAATCACCAGCCCGTAAAGTTGGTCAAATTGACAACCGTGGTAGCCACTACTATCTTGCTATGTA
TTGGGCTGAAGCACTTGCTGCACAAAGCAAGGATGCTGAGTTGCAAGCTTGTTTTGCCTCTGTAGCTAAAGCATTGGCTG
AGAACGAAGAAAAAATTAACGCTGAGTTAATTGGTGCCCAAGGCTCTCCTGTTGATATGGGCGGTTACTATCATCCAAAT
GATGAGCTGACCTCAAAGGCAATGCGCCCAAGTGCCACTTTAAATGCAATTATTGATGCGATCTAA

Upstream 100 bases:

>100_bases
TTGCTGCGGCGGTGTTCTGGTTGGTTTGTTGCTTATTTTTTCTTGTTCTTTCTTCTCTCTTGTAATAACTCTCTCAATCA
ATTAAACCTTATTGTAGCTT

Downstream 100 bases:

>100_bases
GAAGTTGCTTACAAGCTCATAATTGTTTAGAACGCTAAGAAGCCCGGAGTTTTGCTCTGGGCTTCTTTTATTTATGGGGA
AAAAATGCGCACTCAGAGTT

Product: isocitrate dehydrogenase NADP-dependent, monomeric type

Products: NA

Alternate protein names: IDH; Oxalosuccinate decarboxylase [H]

Number of amino acids: Translated: 741; Mature: 740

Protein sequence:

>741_residues
MAQNATIIYTKIDEAPALATYSLLPILQAYFKGTGVTIESSDISLAGRIIANFPENLTESQRIPDNLSALGQLALTPEAN
IIKLPNISASIPQLQAAIKELQEHGYNIPNYPEAPANDAEKELQVRFAKVLGSAVNPVLREGNSDRRAPLSVKNYAKKNP
HKMSAWSADSASHIAHMEGGDFYGSEKSVTVADATNVKIEFVGNDGSSKVLKEKTALLAGEVIDTSVMNVRSLRAFFDQQ
ITDAKENGLLLSLHLKATMMKISDPIMFGHAVTVYYKDVFEKHAATIAELGVNVNNGLGDLYAKIEKLPADKKAAIEADI
QAVYANRPPLAMVDSDKGITNLHVPNDIIVDASMPVVIRDGGKMWGPDGKLHDTKAMVPDRCYATMYQAMVEDCKKNGAF
NPSTIGSVPNVGLMAQKAEEYGSHDKTFTAPANGVIRVVDASGKTLLEQNVETGDIFRMCQTKDAPIRDWVKLAVNRARI
TGAPAIFWLDSNRAHDAQIINKVNEYLKEHDTNGLDIRIMTPVDAMRFSLERFRAGEDTISVTGNVLRDYLTDLFPIIEL
GTSAKMLSIVPLMNGGGLFETGAGGSAPKHVQQFQKEGYLRWDSLGEFSALAASLDHLSRVFNNPKAAVLAETLDEAIGK
FLDTNKSPARKVGQIDNRGSHYYLAMYWAEALAAQSKDAELQACFASVAKALAENEEKINAELIGAQGSPVDMGGYYHPN
DELTSKAMRPSATLNAIIDAI

Sequences:

>Translated_741_residues
MAQNATIIYTKIDEAPALATYSLLPILQAYFKGTGVTIESSDISLAGRIIANFPENLTESQRIPDNLSALGQLALTPEAN
IIKLPNISASIPQLQAAIKELQEHGYNIPNYPEAPANDAEKELQVRFAKVLGSAVNPVLREGNSDRRAPLSVKNYAKKNP
HKMSAWSADSASHIAHMEGGDFYGSEKSVTVADATNVKIEFVGNDGSSKVLKEKTALLAGEVIDTSVMNVRSLRAFFDQQ
ITDAKENGLLLSLHLKATMMKISDPIMFGHAVTVYYKDVFEKHAATIAELGVNVNNGLGDLYAKIEKLPADKKAAIEADI
QAVYANRPPLAMVDSDKGITNLHVPNDIIVDASMPVVIRDGGKMWGPDGKLHDTKAMVPDRCYATMYQAMVEDCKKNGAF
NPSTIGSVPNVGLMAQKAEEYGSHDKTFTAPANGVIRVVDASGKTLLEQNVETGDIFRMCQTKDAPIRDWVKLAVNRARI
TGAPAIFWLDSNRAHDAQIINKVNEYLKEHDTNGLDIRIMTPVDAMRFSLERFRAGEDTISVTGNVLRDYLTDLFPIIEL
GTSAKMLSIVPLMNGGGLFETGAGGSAPKHVQQFQKEGYLRWDSLGEFSALAASLDHLSRVFNNPKAAVLAETLDEAIGK
FLDTNKSPARKVGQIDNRGSHYYLAMYWAEALAAQSKDAELQACFASVAKALAENEEKINAELIGAQGSPVDMGGYYHPN
DELTSKAMRPSATLNAIIDAI
>Mature_740_residues
AQNATIIYTKIDEAPALATYSLLPILQAYFKGTGVTIESSDISLAGRIIANFPENLTESQRIPDNLSALGQLALTPEANI
IKLPNISASIPQLQAAIKELQEHGYNIPNYPEAPANDAEKELQVRFAKVLGSAVNPVLREGNSDRRAPLSVKNYAKKNPH
KMSAWSADSASHIAHMEGGDFYGSEKSVTVADATNVKIEFVGNDGSSKVLKEKTALLAGEVIDTSVMNVRSLRAFFDQQI
TDAKENGLLLSLHLKATMMKISDPIMFGHAVTVYYKDVFEKHAATIAELGVNVNNGLGDLYAKIEKLPADKKAAIEADIQ
AVYANRPPLAMVDSDKGITNLHVPNDIIVDASMPVVIRDGGKMWGPDGKLHDTKAMVPDRCYATMYQAMVEDCKKNGAFN
PSTIGSVPNVGLMAQKAEEYGSHDKTFTAPANGVIRVVDASGKTLLEQNVETGDIFRMCQTKDAPIRDWVKLAVNRARIT
GAPAIFWLDSNRAHDAQIINKVNEYLKEHDTNGLDIRIMTPVDAMRFSLERFRAGEDTISVTGNVLRDYLTDLFPIIELG
TSAKMLSIVPLMNGGGLFETGAGGSAPKHVQQFQKEGYLRWDSLGEFSALAASLDHLSRVFNNPKAAVLAETLDEAIGKF
LDTNKSPARKVGQIDNRGSHYYLAMYWAEALAAQSKDAELQACFASVAKALAENEEKINAELIGAQGSPVDMGGYYHPND
ELTSKAMRPSATLNAIIDAI

Specific function: Unknown

COG id: COG2838

COG function: function code C; Monomeric isocitrate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the monomeric-type IDH family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001804
- InterPro:   IPR004436 [H]

Pfam domain/function: PF03971 IDH [H]

EC number: =1.1.1.42 [H]

Molecular weight: Translated: 80468; Mature: 80337

Theoretical pI: Translated: 5.65; Mature: 5.65

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAQNATIIYTKIDEAPALATYSLLPILQAYFKGTGVTIESSDISLAGRIIANFPENLTES
CCCCCEEEEEECCCCCCHHHHHHHHHHHHHHCCCCEEEECCCCHHHHHHHHHCCHHHHHH
QRIPDNLSALGQLALTPEANIIKLPNISASIPQLQAAIKELQEHGYNIPNYPEAPANDAE
HCCCCCHHHHCCEEECCCCCEEECCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCHH
KELQVRFAKVLGSAVNPVLREGNSDRRAPLSVKNYAKKNPHKMSAWSADSASHIAHMEGG
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHCCCCCCCCCCCCCCCHHEEECCCC
DFYGSEKSVTVADATNVKIEFVGNDGSSKVLKEKTALLAGEVIDTSVMNVRSLRAFFDQQ
CCCCCCCEEEEEECCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ITDAKENGLLLSLHLKATMMKISDPIMFGHAVTVYYKDVFEKHAATIAELGVNVNNGLGD
HCCCCCCCEEEEEEHHHHHHHHCCCEEECCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHH
LYAKIEKLPADKKAAIEADIQAVYANRPPLAMVDSDKGITNLHVPNDIIVDASMPVVIRD
HHHHHHHCCCCCHHHHHHHHHHEECCCCCEEEEECCCCCEEEECCCCEEEECCCCEEEEC
GGKMWGPDGKLHDTKAMVPDRCYATMYQAMVEDCKKNGAFNPSTIGSVPNVGLMAQKAEE
CCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCHHCCCCCCCCHHHHHHHH
YGSHDKTFTAPANGVIRVVDASGKTLLEQNVETGDIFRMCQTKDAPIRDWVKLAVNRARI
HCCCCCEEECCCCCEEEEEECCCCHHHHCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHEE
TGAPAIFWLDSNRAHDAQIINKVNEYLKEHDTNGLDIRIMTPVDAMRFSLERFRAGEDTI
CCCCEEEEECCCCCHHHHHHHHHHHHHHHCCCCCEEEEEECCHHHHHHHHHHHHCCCCEE
SVTGNVLRDYLTDLFPIIELGTSAKMLSIVPLMNGGGLFETGAGGSAPKHVQQFQKEGYL
EHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEECCCCEEECCCCCCCHHHHHHHHHCCCE
RWDSLGEFSALAASLDHLSRVFNNPKAAVLAETLDEAIGKFLDTNKSPARKVGQIDNRGS
ECCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHCCCCCCCC
HYYLAMYWAEALAAQSKDAELQACFASVAKALAENEEKINAELIGAQGSPVDMGGYYHPN
EEEEHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCHHHCCEEEECCCCCCCCCCCEECCC
DELTSKAMRPSATLNAIIDAI
HHHHHHHCCCCHHHHHHHHCC
>Mature Secondary Structure 
AQNATIIYTKIDEAPALATYSLLPILQAYFKGTGVTIESSDISLAGRIIANFPENLTES
CCCCEEEEEECCCCCCHHHHHHHHHHHHHHCCCCEEEECCCCHHHHHHHHHCCHHHHHH
QRIPDNLSALGQLALTPEANIIKLPNISASIPQLQAAIKELQEHGYNIPNYPEAPANDAE
HCCCCCHHHHCCEEECCCCCEEECCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCHH
KELQVRFAKVLGSAVNPVLREGNSDRRAPLSVKNYAKKNPHKMSAWSADSASHIAHMEGG
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHCCCCCCCCCCCCCCCHHEEECCCC
DFYGSEKSVTVADATNVKIEFVGNDGSSKVLKEKTALLAGEVIDTSVMNVRSLRAFFDQQ
CCCCCCCEEEEEECCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ITDAKENGLLLSLHLKATMMKISDPIMFGHAVTVYYKDVFEKHAATIAELGVNVNNGLGD
HCCCCCCCEEEEEEHHHHHHHHCCCEEECCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHH
LYAKIEKLPADKKAAIEADIQAVYANRPPLAMVDSDKGITNLHVPNDIIVDASMPVVIRD
HHHHHHHCCCCCHHHHHHHHHHEECCCCCEEEEECCCCCEEEECCCCEEEECCCCEEEEC
GGKMWGPDGKLHDTKAMVPDRCYATMYQAMVEDCKKNGAFNPSTIGSVPNVGLMAQKAEE
CCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCHHCCCCCCCCHHHHHHHH
YGSHDKTFTAPANGVIRVVDASGKTLLEQNVETGDIFRMCQTKDAPIRDWVKLAVNRARI
HCCCCCEEECCCCCEEEEEECCCCHHHHCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHEE
TGAPAIFWLDSNRAHDAQIINKVNEYLKEHDTNGLDIRIMTPVDAMRFSLERFRAGEDTI
CCCCEEEEECCCCCHHHHHHHHHHHHHHHCCCCCEEEEEECCHHHHHHHHHHHHCCCCEE
SVTGNVLRDYLTDLFPIIELGTSAKMLSIVPLMNGGGLFETGAGGSAPKHVQQFQKEGYL
EHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEECCCCEEECCCCCCCHHHHHHHHHCCCE
RWDSLGEFSALAASLDHLSRVFNNPKAAVLAETLDEAIGKFLDTNKSPARKVGQIDNRGS
ECCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHCCCCCCCC
HYYLAMYWAEALAAQSKDAELQACFASVAKALAENEEKINAELIGAQGSPVDMGGYYHPN
EEEEHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCHHHCCEEEECCCCCCCCCCCEECCC
DELTSKAMRPSATLNAIIDAI
HHHHHHHCCCCHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12005040; 4149369; 12467571 [H]