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The map label for this gene is fabI1 [H]

Identifier: 78189374

GI number: 78189374

Start: 1879918

End: 1880796

Strand: Reverse

Name: fabI1 [H]

Synonym: Cag_1411

Alternate gene names: 78189374

Gene position: 1880796-1879918 (Counterclockwise)

Preceding gene: 78189375

Following gene: 78189373

Centisome position: 73.12

GC content: 43.23

Gene sequence:

>879_bases
ATGTCCGAGAAAGCGCATTACGGTTTATTAAAAGGAAAAAAAGGAATTGTCTTCGGTCCTCTTGATGAAAGCAGTATTGG
CTGGCAAATTGCCTTATATGCTTACAACGAGGGGGCAACCATTGCCATCTCGAACATAGCAGCGGCACAGCGTTTTGGCA
ATATGGATGAGCTTTCAGCCTTATGTGGTAATGCTCCCATTATTGTATGCGATGCCTCAAAAAATGAGGATGTTGATAAC
TGTTTTCGTGAGCTCAAAGAAAAAATTGGCTCTGTTGACTTTATTGTACACTCTATTGGCATGTCGCAAAACATTCGTAA
GCAAATGCCATACGAGGATCTTAATTACGAGTGGTTTGTTAGAACGCTTGATGTTTCAGCACTCTCATTGCACCGTATTG
TGTCGTATGCACTAAAGCATGAAGCCATTAACCCTGGCGGTAGTATTCTTGCGCTCTCCTACATTGCATCACAGCGCAAT
TACTGGACATACTCCGATATGGGCGATGCAAAATCACTGCTTGAGTCTATTGTGCGGAGTTATGGACCTCGCCTTGCACG
TAAAGGTATTCGTATTAACACGATATCTCAAAGCCCAACCTACACCAAAGCAGGTAGTGGTATTCCTGGGTTTGATAAAA
TGTATGAATATAGCGACTTAATGTCGCCCCTTGGCAATGCCTCGGCTGAAGAGTGTGCCGAATATACTATGACGATTCTT
AGCGACCTTTCACGTAAGGTTACTATGCAGAATTTGTTCCATGATGGTGGATATAGCTCTATGGGTGCCACTATTCCAAT
GATCAAGCTTGCTCACGAAGTGCTTAACGATAAAGAACTTGCTGAGCGCGTTGGGCTTGATGAATTTATGCCTTCCTAA

Upstream 100 bases:

>100_bases
TATATTTTTAGGTTTTCAGTTGAAAACCGTATCTTGAACACTTACAGTCCCCCGACGACAAGGGAATTATCCCACTTTTT
TAAAGAATCAGCATTCCATT

Downstream 100 bases:

>100_bases
GTAGTTTTCTTTTTGCACAAGCAACGTAATACCATTGCTTTGCTTGTGCCTTTTTTACAGGACTATCATTTTTTTACATA
CAAGGCTTATTTGTGCCGTG

Product: enoyl-(acyl-carrier protein) reductase (NADH)

Products: NA

Alternate protein names: NADH-dependent enoyl-ACP reductase 1 [H]

Number of amino acids: Translated: 292; Mature: 291

Protein sequence:

>292_residues
MSEKAHYGLLKGKKGIVFGPLDESSIGWQIALYAYNEGATIAISNIAAAQRFGNMDELSALCGNAPIIVCDASKNEDVDN
CFRELKEKIGSVDFIVHSIGMSQNIRKQMPYEDLNYEWFVRTLDVSALSLHRIVSYALKHEAINPGGSILALSYIASQRN
YWTYSDMGDAKSLLESIVRSYGPRLARKGIRINTISQSPTYTKAGSGIPGFDKMYEYSDLMSPLGNASAEECAEYTMTIL
SDLSRKVTMQNLFHDGGYSSMGATIPMIKLAHEVLNDKELAERVGLDEFMPS

Sequences:

>Translated_292_residues
MSEKAHYGLLKGKKGIVFGPLDESSIGWQIALYAYNEGATIAISNIAAAQRFGNMDELSALCGNAPIIVCDASKNEDVDN
CFRELKEKIGSVDFIVHSIGMSQNIRKQMPYEDLNYEWFVRTLDVSALSLHRIVSYALKHEAINPGGSILALSYIASQRN
YWTYSDMGDAKSLLESIVRSYGPRLARKGIRINTISQSPTYTKAGSGIPGFDKMYEYSDLMSPLGNASAEECAEYTMTIL
SDLSRKVTMQNLFHDGGYSSMGATIPMIKLAHEVLNDKELAERVGLDEFMPS
>Mature_291_residues
SEKAHYGLLKGKKGIVFGPLDESSIGWQIALYAYNEGATIAISNIAAAQRFGNMDELSALCGNAPIIVCDASKNEDVDNC
FRELKEKIGSVDFIVHSIGMSQNIRKQMPYEDLNYEWFVRTLDVSALSLHRIVSYALKHEAINPGGSILALSYIASQRNY
WTYSDMGDAKSLLESIVRSYGPRLARKGIRINTISQSPTYTKAGSGIPGFDKMYEYSDLMSPLGNASAEECAEYTMTILS
DLSRKVTMQNLFHDGGYSSMGATIPMIKLAHEVLNDKELAERVGLDEFMPS

Specific function: Fatty acid biosynthesis pathway; second reduction step. [C]

COG id: COG0623

COG function: function code I; Enoyl-[acyl-carrier-protein] reductase (NADH)

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily [H]

Homologues:

Organism=Escherichia coli, GI1787545, Length=254, Percent_Identity=30.3149606299213, Blast_Score=112, Evalue=3e-26,

Paralogues:

None

Copy number: 200 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 240 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR014358
- InterPro:   IPR002347
- InterPro:   IPR016040 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: =1.3.1.9 [H]

Molecular weight: Translated: 32257; Mature: 32126

Theoretical pI: Translated: 5.39; Mature: 5.39

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEKAHYGLLKGKKGIVFGPLDESSIGWQIALYAYNEGATIAISNIAAAQRFGNMDELSA
CCCCCCCCHHCCCCCCEECCCCCCCCCEEEEEEEECCCCEEEEHHHHHHHHCCCHHHHHH
LCGNAPIIVCDASKNEDVDNCFRELKEKIGSVDFIVHSIGMSQNIRKQMPYEDLNYEWFV
HHCCCCEEEEECCCCCCHHHHHHHHHHHHCCHHHHHHHHCCCHHHHHHCCCCCCCCEEEE
RTLDVSALSLHRIVSYALKHEAINPGGSILALSYIASQRNYWTYSDMGDAKSLLESIVRS
EEHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCEECCCCCHHHHHHHHHHHH
YGPRLARKGIRINTISQSPTYTKAGSGIPGFDKMYEYSDLMSPLGNASAEECAEYTMTIL
HCHHHHHCCCEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHH
SDLSRKVTMQNLFHDGGYSSMGATIPMIKLAHEVLNDKELAERVGLDEFMPS
HHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCHHHHHHHCCHHHHCCC
>Mature Secondary Structure 
SEKAHYGLLKGKKGIVFGPLDESSIGWQIALYAYNEGATIAISNIAAAQRFGNMDELSA
CCCCCCCHHCCCCCCEECCCCCCCCCEEEEEEEECCCCEEEEHHHHHHHHCCCHHHHHH
LCGNAPIIVCDASKNEDVDNCFRELKEKIGSVDFIVHSIGMSQNIRKQMPYEDLNYEWFV
HHCCCCEEEEECCCCCCHHHHHHHHHHHHCCHHHHHHHHCCCHHHHHHCCCCCCCCEEEE
RTLDVSALSLHRIVSYALKHEAINPGGSILALSYIASQRNYWTYSDMGDAKSLLESIVRS
EEHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCEECCCCCHHHHHHHHHHHH
YGPRLARKGIRINTISQSPTYTKAGSGIPGFDKMYEYSDLMSPLGNASAEECAEYTMTIL
HCHHHHHCCCEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHH
SDLSRKVTMQNLFHDGGYSSMGATIPMIKLAHEVLNDKELAERVGLDEFMPS
HHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCHHHHHHHCCHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11481430 [H]