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The map label for this gene is yieH [H]

Identifier: 78067484

GI number: 78067484

Start: 3149958

End: 3150644

Strand: Direct

Name: yieH [H]

Synonym: Bcep18194_A6015

Alternate gene names: 78067484

Gene position: 3149958-3150644 (Clockwise)

Preceding gene: 78067483

Following gene: 78067489

Centisome position: 85.27

GC content: 66.81

Gene sequence:

>687_bases
ATGCTCGATCACCTCATCTGCGACTGCGACGGCGTGCTCGTCGACAGCGAAGTCATCGCCGACCGCGTCCTGCTCGACAC
GCTGTCCGCCACGTTCCCGAATCTCGATTTCGAAGCCGCCGCCAAGTCGGCGTTCGGCCAGCAGACGTCGCGCTTCCTGG
CGGGAATCGAATCCCGCTTCGGGATCGAGATGCCGGCCAACTTCATCGAGACCATCGAGCACAACATCGAGAGCGCGCTG
GCGCAATCGCTCGCGCCGATCTCCGGCGTGCGCGACGCGCTGCTGAAGGTGAGCCTGCCGGTGGCCGTCGTGTCGAACAG
CCGGCTCGCGCGCGTGCGCAGCTCGCTGAAGCGTGCGTCGCTCACCGAGATCTTCGGCGATCGCGTGTTCAGTTCCGAGC
AGGTGGCGCGTCCGAAGCCCTACCCCGATGTGTACCTGCACGCGGCGCACACGCTCGGCGTCGCGCCGGAGCGCTGCATC
GTCGTCGAGGACAGCGTGTCGGGGTTGAATGCCGCACGTGCGGCGGGCATGAAGACGATCGCGTTCGTCGGCGCGAGCCA
CATCCCCGACAACTACGCGGACGCGCTGCGCGCGATGGGCATCACGCGAATCATGCGCAAGATGGACGAACTGCCGGCGT
TCGTCGAAGCCGGCATGCGCGGCGAATTCGGCGACGTGCAGTCCTGA

Upstream 100 bases:

>100_bases
CGCATCGGGAAAATTTGCCGAAGCGTCGCGCGGCGTCGGCGTGAAAACACGTATGATGGCGAATTGATCTGCGTCGCCGA
CATCCCGCTTTTTCACCACC

Downstream 100 bases:

>100_bases
TGCTTTTGACGGCCCGACCAGGCTGATCGGGCCGATCCGGCGTGCGCCGGTTCACGCACGCCGTGCCACGGGCGCGAACG
CGCCCGCCTTCCTTTCCCTC

Product: HAD family hydrolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 228; Mature: 228

Protein sequence:

>228_residues
MLDHLICDCDGVLVDSEVIADRVLLDTLSATFPNLDFEAAAKSAFGQQTSRFLAGIESRFGIEMPANFIETIEHNIESAL
AQSLAPISGVRDALLKVSLPVAVVSNSRLARVRSSLKRASLTEIFGDRVFSSEQVARPKPYPDVYLHAAHTLGVAPERCI
VVEDSVSGLNAARAAGMKTIAFVGASHIPDNYADALRAMGITRIMRKMDELPAFVEAGMRGEFGDVQS

Sequences:

>Translated_228_residues
MLDHLICDCDGVLVDSEVIADRVLLDTLSATFPNLDFEAAAKSAFGQQTSRFLAGIESRFGIEMPANFIETIEHNIESAL
AQSLAPISGVRDALLKVSLPVAVVSNSRLARVRSSLKRASLTEIFGDRVFSSEQVARPKPYPDVYLHAAHTLGVAPERCI
VVEDSVSGLNAARAAGMKTIAFVGASHIPDNYADALRAMGITRIMRKMDELPAFVEAGMRGEFGDVQS
>Mature_228_residues
MLDHLICDCDGVLVDSEVIADRVLLDTLSATFPNLDFEAAAKSAFGQQTSRFLAGIESRFGIEMPANFIETIEHNIESAL
AQSLAPISGVRDALLKVSLPVAVVSNSRLARVRSSLKRASLTEIFGDRVFSSEQVARPKPYPDVYLHAAHTLGVAPERCI
VVEDSVSGLNAARAAGMKTIAFVGASHIPDNYADALRAMGITRIMRKMDELPAFVEAGMRGEFGDVQS

Specific function: Catalyzes the dephosphorylation of the artificial chromogenic substrate p-nitrophenyl phosphate (pNPP) and of the natural substrates phosphoenolpyruvate and AMP [H]

COG id: COG0637

COG function: function code R; Predicted phosphatase/phosphohexomutase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HAD-like hydrolase superfamily. CbbY/CbbZ/Gph/YieH family [H]

Homologues:

Organism=Escherichia coli, GI1790151, Length=181, Percent_Identity=29.8342541436464, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI1788021, Length=181, Percent_Identity=32.0441988950276, Blast_Score=70, Evalue=1e-13,
Organism=Drosophila melanogaster, GI20129151, Length=245, Percent_Identity=28.1632653061224, Blast_Score=72, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005834
- InterPro:   IPR023214
- InterPro:   IPR006439
- InterPro:   IPR006402
- InterPro:   IPR005833 [H]

Pfam domain/function: PF00702 Hydrolase [H]

EC number: NA

Molecular weight: Translated: 24563; Mature: 24563

Theoretical pI: Translated: 5.10; Mature: 5.10

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLDHLICDCDGVLVDSEVIADRVLLDTLSATFPNLDFEAAAKSAFGQQTSRFLAGIESRF
CCCCEEECCCCEEECHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHC
GIEMPANFIETIEHNIESALAQSLAPISGVRDALLKVSLPVAVVSNSRLARVRSSLKRAS
CCCCCHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHCCHHHHCCCHHHHHHHHHHHHH
LTEIFGDRVFSSEQVARPKPYPDVYLHAAHTLGVAPERCIVVEDSVSGLNAARAAGMKTI
HHHHHHHHHCCCCCCCCCCCCCHHEEEHHHHHCCCCCEEEEEECCCCCHHHHHHHCHHHH
AFVGASHIPDNYADALRAMGITRIMRKMDELPAFVEAGMRGEFGDVQS
HHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure
MLDHLICDCDGVLVDSEVIADRVLLDTLSATFPNLDFEAAAKSAFGQQTSRFLAGIESRF
CCCCEEECCCCEEECHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHC
GIEMPANFIETIEHNIESALAQSLAPISGVRDALLKVSLPVAVVSNSRLARVRSSLKRAS
CCCCCHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHCCHHHHCCCHHHHHHHHHHHHH
LTEIFGDRVFSSEQVARPKPYPDVYLHAAHTLGVAPERCIVVEDSVSGLNAARAAGMKTI
HHHHHHHHHCCCCCCCCCCCCCHHEEEHHHHHCCCCCEEEEEECCCCCHHHHHHHCHHHH
AFVGASHIPDNYADALRAMGITRIMRKMDELPAFVEAGMRGEFGDVQS
HHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7686882; 9278503 [H]