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The map label for this gene is yrbE [H]

Identifier: 78067483

GI number: 78067483

Start: 3148704

End: 3149765

Strand: Direct

Name: yrbE [H]

Synonym: Bcep18194_A6014

Alternate gene names: 78067483

Gene position: 3148704-3149765 (Clockwise)

Preceding gene: 78067482

Following gene: 78067484

Centisome position: 85.24

GC content: 68.83

Gene sequence:

>1062_bases
ATGACTGCCGCCACGGCGTGCGGTCGACTTGAACCACGCGCCGGCGGAAAACCACAACATCAACAGGAGAACGGAATGAT
CGAATTCGCGTTGTTCGGCGCGGGACGCATCGGCAAGATCCACGCGGCGAATCTCGCGCGCCATCCGGGTGCGAAGCTGA
AGTACGTCGTCGACCGGCATGCGCCGTCGGCCGAAGCGCTGGCCCATGCGCACGGCGCGCAGGTGGCCGACGTAGAACGC
GCGCTCGGCGATCCGGCGATTACGGCGGTCGTGATCGCATCGAGCACCGACACGCATGCCGACCTGATCGTCGCGGCGGC
GAATGCGGGCAAGGCCGTGTTCTGCGAGAAGCCCGTCGACCTGACCGTCGAGCGCTCGCGTGTGTGCGCGGACGTCGTCC
GGCGCAGCGGCGTGACCTGCATGATCGGCTTCCAGCGCCGCTTCGACCCGACGTTCGCCGCGCTGAAGGCGCGCGTCGAG
CGCGGCGAGATCGGTGCGCCTGAAATGCTGGTCGTCACGAGCCGCGACCCGGGCGCGCCGCCCGTCGACTACATCCGCAG
CTCGGGCGGCATCTTCAAGGACATGCTGATCCACGATTTCGACGTGTTCCGCTGGATCCTCGGCGACGAAGCGCAGACGC
TGCACGCGACCGGCAGCTGCCTGACCGATCCGGCCGTGCACGACGCGGGCGACATCGATTCGACTGCCGTGACGATCCGC
ACGCGGCGCGGGCTGCTGTGCCAGATCAACACGTCGCGGCGCGCCGCCTACGGCTACGACCAGCGTTTCGAGCTGCTCGG
CAGCCACGGGATGCTGCAGGCCGGCAACGTGCGGCCGACCGAGGTGAGCGCGTGGCTCGCGGCCGGCATCGCGACGGATG
TGCCGGAGCCGTTCTTCCTCGAACGCTACCGGCATGCGTACGCGGCCGAGATCGCGCACTTCGTCGACGCGCTGCGCGAC
GGCACGCCGGTCCGCACGACGATCGACGACGGGCTCGCCGCGCTCGAACTGGCCGAGGCCGCGATGACGTCATGGAAAAC
GGGGCGCGTAATCGAGCTGTAA

Upstream 100 bases:

>100_bases
TCTCGTTCGAGCCGTTCGCAAACGAAATCGCCGAAGCCGACGACATCGAGGACCGGCTGCGTTCGAGCATCGACTACGTG
CGCGGTGAGCTGGCGGCTCA

Downstream 100 bases:

>100_bases
CGTCACCGGTAGCAAGCGGCGGCACACCGCTCAAGCGGGTCGCCGCCGGACGATCGGCTGCACACCGGAACGGCCTGTAG
CGAGCACGCCGTCGCATCGG

Product: myo-inositol 2-dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 353; Mature: 352

Protein sequence:

>353_residues
MTAATACGRLEPRAGGKPQHQQENGMIEFALFGAGRIGKIHAANLARHPGAKLKYVVDRHAPSAEALAHAHGAQVADVER
ALGDPAITAVVIASSTDTHADLIVAAANAGKAVFCEKPVDLTVERSRVCADVVRRSGVTCMIGFQRRFDPTFAALKARVE
RGEIGAPEMLVVTSRDPGAPPVDYIRSSGGIFKDMLIHDFDVFRWILGDEAQTLHATGSCLTDPAVHDAGDIDSTAVTIR
TRRGLLCQINTSRRAAYGYDQRFELLGSHGMLQAGNVRPTEVSAWLAAGIATDVPEPFFLERYRHAYAAEIAHFVDALRD
GTPVRTTIDDGLAALELAEAAMTSWKTGRVIEL

Sequences:

>Translated_353_residues
MTAATACGRLEPRAGGKPQHQQENGMIEFALFGAGRIGKIHAANLARHPGAKLKYVVDRHAPSAEALAHAHGAQVADVER
ALGDPAITAVVIASSTDTHADLIVAAANAGKAVFCEKPVDLTVERSRVCADVVRRSGVTCMIGFQRRFDPTFAALKARVE
RGEIGAPEMLVVTSRDPGAPPVDYIRSSGGIFKDMLIHDFDVFRWILGDEAQTLHATGSCLTDPAVHDAGDIDSTAVTIR
TRRGLLCQINTSRRAAYGYDQRFELLGSHGMLQAGNVRPTEVSAWLAAGIATDVPEPFFLERYRHAYAAEIAHFVDALRD
GTPVRTTIDDGLAALELAEAAMTSWKTGRVIEL
>Mature_352_residues
TAATACGRLEPRAGGKPQHQQENGMIEFALFGAGRIGKIHAANLARHPGAKLKYVVDRHAPSAEALAHAHGAQVADVERA
LGDPAITAVVIASSTDTHADLIVAAANAGKAVFCEKPVDLTVERSRVCADVVRRSGVTCMIGFQRRFDPTFAALKARVER
GEIGAPEMLVVTSRDPGAPPVDYIRSSGGIFKDMLIHDFDVFRWILGDEAQTLHATGSCLTDPAVHDAGDIDSTAVTIRT
RRGLLCQINTSRRAAYGYDQRFELLGSHGMLQAGNVRPTEVSAWLAAGIATDVPEPFFLERYRHAYAAEIAHFVDALRDG
TPVRTTIDDGLAALELAEAAMTSWKTGRVIEL

Specific function: Unknown

COG id: COG0673

COG function: function code R; Predicted dehydrogenases and related proteins

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the gfo/idh/mocA family [H]

Homologues:

Organism=Escherichia coli, GI1789848, Length=168, Percent_Identity=27.3809523809524, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI1787574, Length=249, Percent_Identity=28.9156626506024, Blast_Score=62, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016040
- InterPro:   IPR000683
- InterPro:   IPR004104 [H]

Pfam domain/function: PF01408 GFO_IDH_MocA; PF02894 GFO_IDH_MocA_C [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 37899; Mature: 37768

Theoretical pI: Translated: 6.70; Mature: 6.70

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTAATACGRLEPRAGGKPQHQQENGMIEFALFGAGRIGKIHAANLARHPGAKLKYVVDRH
CCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEECCCCCCEEEHHHHCCCCCCCEEEEEECC
APSAEALAHAHGAQVADVERALGDPAITAVVIASSTDTHADLIVAAANAGKAVFCEKPVD
CCHHHHHHHHCCCHHHHHHHHHCCCCEEEEEEECCCCCCCEEEEEECCCCCEEEECCCCC
LTVERSRVCADVVRRSGVTCMIGFQRRFDPTFAALKARVERGEIGAPEMLVVTSRDPGAP
CEEHHHHHHHHHHHHCCCEEEEECCCCCCHHHHHHHHHHHCCCCCCCCEEEEECCCCCCC
PVDYIRSSGGIFKDMLIHDFDVFRWILGDEAQTLHATGSCLTDPAVHDAGDIDSTAVTIR
HHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCCCCCCEEEEEE
TRRGLLCQINTSRRAAYGYDQRFELLGSHGMLQAGNVRPTEVSAWLAAGIATDVPEPFFL
ECCCEEEEEECCCCCCCCCCHHHHHHCCCCCEECCCCCCHHHHHHHHHHHHHCCCCHHHH
ERYRHAYAAEIAHFVDALRDGTPVRTTIDDGLAALELAEAAMTSWKTGRVIEL
HHHHHHHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHHHHCCCCCCEEEC
>Mature Secondary Structure 
TAATACGRLEPRAGGKPQHQQENGMIEFALFGAGRIGKIHAANLARHPGAKLKYVVDRH
CCCCCCCCCCCCCCCCCCCCCCCCEEEEEEECCCCCCEEEHHHHCCCCCCCEEEEEECC
APSAEALAHAHGAQVADVERALGDPAITAVVIASSTDTHADLIVAAANAGKAVFCEKPVD
CCHHHHHHHHCCCHHHHHHHHHCCCCEEEEEEECCCCCCCEEEEEECCCCCEEEECCCCC
LTVERSRVCADVVRRSGVTCMIGFQRRFDPTFAALKARVERGEIGAPEMLVVTSRDPGAP
CEEHHHHHHHHHHHHCCCEEEEECCCCCCHHHHHHHHHHHCCCCCCCCEEEEECCCCCCC
PVDYIRSSGGIFKDMLIHDFDVFRWILGDEAQTLHATGSCLTDPAVHDAGDIDSTAVTIR
HHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCCCCCCEEEEEE
TRRGLLCQINTSRRAAYGYDQRFELLGSHGMLQAGNVRPTEVSAWLAAGIATDVPEPFFL
ECCCEEEEEECCCCCCCCCCHHHHHHCCCCCEECCCCCCHHHHHHHHHHHHHCCCCHHHH
ERYRHAYAAEIAHFVDALRDGTPVRTTIDDGLAALELAEAAMTSWKTGRVIEL
HHHHHHHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHHHHCCCCCCEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377; 9025289 [H]