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The map label for this gene is dalD [H]

Identifier: 78067385

GI number: 78067385

Start: 3038278

End: 3039672

Strand: Direct

Name: dalD [H]

Synonym: Bcep18194_A5916

Alternate gene names: 78067385

Gene position: 3038278-3039672 (Clockwise)

Preceding gene: 78067384

Following gene: 78067386

Centisome position: 82.25

GC content: 70.82

Gene sequence:

>1395_bases
ATGAGCGCATCGCCCTCCGCCCGCACGCCCGTGCTGCTGCACATCGGCGCGGGCTCGTTTCACCGCGCGCACCAAGCGTG
GTATCTGCATCGCGTGAACGCGGCCGTCCCGGCCGACGAGCGCTGGTCGCTGACCGTCGGCAACATCCGCGACGACATGC
ACGCGACGATGGACGCGCTCGCCGCGCAGCACGGCGCCTACACGCTCGAAACCGTCACGCCGCAAGGCGAGCGCGCGTAC
GAGACGATCCGCGCGATCACGCGCGTGCTGCCGTGGTCGATCGACCTCGCCGCGCTGATCGATGCCGGCGCCGATCCGGA
CTGCCGGATCGTGTCGTTCACCGTCACGGAAGGCGGCTACTACCTCGACGAACACAACCGGCTCGACCTCGCGAACGCCG
ATCTCGCGGCCGACCTGCAGGGCGCGCGCACGACGCTGTACGGCGCGCTCGCGGCGCTGCTCGCCGAACGCGTGACCCGC
GGCGCGGGCCCGCTCACGCTGCAGAGCTGCGACAACCTGCGCAACAACGGCGCGCGCTTTCGTGCGGGAATGCGTGAATT
CCTCGAACGGCGCGGACAGGCCGACCTGCTCGCATGGTTCGATGCGAACGTTGCGACACCCAGCGCGATGGTCGACCGCA
TCACGCCGCGCCCGACCGCCGACGTGCGCGAGCGCGTGCTGGCGGCCACCGGCGTCGACGACGCGTGCCCGGTAATGGGC
GAATCGTTCATCCAGTGGGTGATCGAAGACCGCTTTGCGGCCGGCCGGCCGCGCTGGGAGCTGGCCGGCGCCGAACTCGT
CGACGACGTGCACCCGTACGAGGAAGCGAAGATCCGCATCCTCAACGCGACGCACAGCTGCATCGCGTGGGCCGGCACGC
TCGCGGGCCACACGTATATCCACGAAGGCACGCACGACGCGGCGATCCGCCGCTTCGCGCACGACTACGTGACGCAGGAC
GTGATCCCCTGCCTCACGCCGAGCCCGCTCGATCTCGCGCGCTACCGCGACGTCGTGCTCGAACGCTTCGGCAACCCGTA
CGTGCTGGACACGAACCAGCGCGTCGCGGCCGACGGCTTCTCGAAGATCCCCGGCTTCATCGCGCCGACGCTCGCCGAAT
CGTTCGCACGCGGCGCATCGCCGATCGCGACCGCCGTGCTGCCCGCGCTGTTCCTGCGCTTTCTCGAACGCTGGGCGCGC
GGCGCGCTGCCGTATGCGTACCAGGACGGCGTGATGGACGAAAGCGCTGCACGGGCGATCGTCGGCGCCACCGACCCCGT
CGTCGCGCTGTGCGCGAACCGGCAGCTGTGGGGCTCGCTCGCCGGCAACGCGGCGCTGTTCGAGGCCATCCGCGGCGGAC
TCTGGCGCGTCGACGCATGGCTCGCGGCACGCTGA

Upstream 100 bases:

>100_bases
CCCGCCTTGACTTTCGCTCGCCCGAATACGATCATTCGCTCACACAAAGAGCAAATGATCGTATTCGACAGGACAGTCAG
GCACGAACAGGAGACCCCGG

Downstream 100 bases:

>100_bases
CGCGCATCCGGGCGAACCTGCCTTGGCACGGGCGCGGCCGCGCGGCTAAAGTAGCGACTCCCCACTGACGGAACGGATCG
CTCATGTATCTCGGCATCGA

Product: mannitol dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 464; Mature: 463

Protein sequence:

>464_residues
MSASPSARTPVLLHIGAGSFHRAHQAWYLHRVNAAVPADERWSLTVGNIRDDMHATMDALAAQHGAYTLETVTPQGERAY
ETIRAITRVLPWSIDLAALIDAGADPDCRIVSFTVTEGGYYLDEHNRLDLANADLAADLQGARTTLYGALAALLAERVTR
GAGPLTLQSCDNLRNNGARFRAGMREFLERRGQADLLAWFDANVATPSAMVDRITPRPTADVRERVLAATGVDDACPVMG
ESFIQWVIEDRFAAGRPRWELAGAELVDDVHPYEEAKIRILNATHSCIAWAGTLAGHTYIHEGTHDAAIRRFAHDYVTQD
VIPCLTPSPLDLARYRDVVLERFGNPYVLDTNQRVAADGFSKIPGFIAPTLAESFARGASPIATAVLPALFLRFLERWAR
GALPYAYQDGVMDESAARAIVGATDPVVALCANRQLWGSLAGNAALFEAIRGGLWRVDAWLAAR

Sequences:

>Translated_464_residues
MSASPSARTPVLLHIGAGSFHRAHQAWYLHRVNAAVPADERWSLTVGNIRDDMHATMDALAAQHGAYTLETVTPQGERAY
ETIRAITRVLPWSIDLAALIDAGADPDCRIVSFTVTEGGYYLDEHNRLDLANADLAADLQGARTTLYGALAALLAERVTR
GAGPLTLQSCDNLRNNGARFRAGMREFLERRGQADLLAWFDANVATPSAMVDRITPRPTADVRERVLAATGVDDACPVMG
ESFIQWVIEDRFAAGRPRWELAGAELVDDVHPYEEAKIRILNATHSCIAWAGTLAGHTYIHEGTHDAAIRRFAHDYVTQD
VIPCLTPSPLDLARYRDVVLERFGNPYVLDTNQRVAADGFSKIPGFIAPTLAESFARGASPIATAVLPALFLRFLERWAR
GALPYAYQDGVMDESAARAIVGATDPVVALCANRQLWGSLAGNAALFEAIRGGLWRVDAWLAAR
>Mature_463_residues
SASPSARTPVLLHIGAGSFHRAHQAWYLHRVNAAVPADERWSLTVGNIRDDMHATMDALAAQHGAYTLETVTPQGERAYE
TIRAITRVLPWSIDLAALIDAGADPDCRIVSFTVTEGGYYLDEHNRLDLANADLAADLQGARTTLYGALAALLAERVTRG
AGPLTLQSCDNLRNNGARFRAGMREFLERRGQADLLAWFDANVATPSAMVDRITPRPTADVRERVLAATGVDDACPVMGE
SFIQWVIEDRFAAGRPRWELAGAELVDDVHPYEEAKIRILNATHSCIAWAGTLAGHTYIHEGTHDAAIRRFAHDYVTQDV
IPCLTPSPLDLARYRDVVLERFGNPYVLDTNQRVAADGFSKIPGFIAPTLAESFARGASPIATAVLPALFLRFLERWARG
ALPYAYQDGVMDESAARAIVGATDPVVALCANRQLWGSLAGNAALFEAIRGGLWRVDAWLAAR

Specific function: Unknown

COG id: COG0246

COG function: function code G; Mannitol-1-phosphate/altronate dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mannitol dehydrogenase family [H]

Homologues:

Organism=Escherichia coli, GI1788497, Length=358, Percent_Identity=36.3128491620112, Blast_Score=211, Evalue=7e-56,
Organism=Escherichia coli, GI1787823, Length=365, Percent_Identity=36.7123287671233, Blast_Score=199, Evalue=4e-52,
Organism=Escherichia coli, GI1790779, Length=361, Percent_Identity=35.1800554016621, Blast_Score=197, Evalue=9e-52,
Organism=Escherichia coli, GI48994885, Length=425, Percent_Identity=25.4117647058824, Blast_Score=92, Evalue=5e-20,
Organism=Escherichia coli, GI1790028, Length=367, Percent_Identity=24.2506811989101, Blast_Score=75, Evalue=8e-15,
Organism=Saccharomyces cerevisiae, GI6324401, Length=422, Percent_Identity=37.4407582938389, Blast_Score=264, Evalue=3e-71,
Organism=Saccharomyces cerevisiae, GI6320765, Length=422, Percent_Identity=37.4407582938389, Blast_Score=264, Evalue=3e-71,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008927
- InterPro:   IPR013328
- InterPro:   IPR000669
- InterPro:   IPR013118
- InterPro:   IPR013131
- InterPro:   IPR016040 [H]

Pfam domain/function: PF01232 Mannitol_dh; PF08125 Mannitol_dh_C [H]

EC number: =1.1.1.11 [H]

Molecular weight: Translated: 50591; Mature: 50459

Theoretical pI: Translated: 5.91; Mature: 5.91

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSASPSARTPVLLHIGAGSFHRAHQAWYLHRVNAAVPADERWSLTVGNIRDDMHATMDAL
CCCCCCCCCCEEEEECCCCHHHHHHHHHHEECCCCCCCCCCCEEEECCHHHHHHHHHHHH
AAQHGAYTLETVTPQGERAYETIRAITRVLPWSIDLAALIDAGADPDCRIVSFTVTEGGY
HHHCCCEEEEEECCCCHHHHHHHHHHHHHCCCCCCHHHHHCCCCCCCCEEEEEEEECCCE
YLDEHNRLDLANADLAADLQGARTTLYGALAALLAERVTRGAGPLTLQSCDNLRNNGARF
EECCCCCEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEHHHHHHHHCCCHHH
RAGMREFLERRGQADLLAWFDANVATPSAMVDRITPRPTADVRERVLAATGVDDACPVMG
HHHHHHHHHHCCCCCEEEEECCCCCCHHHHHHCCCCCCCHHHHHHHHHHCCCCCCCHHHH
ESFIQWVIEDRFAAGRPRWELAGAELVDDVHPYEEAKIRILNATHSCIAWAGTLAGHTYI
HHHHHHHHHHHHHCCCCCCEECCHHHHHHCCCCCCCEEEEEECCHHHHHHHHHHHCCCEE
HEGTHDAAIRRFAHDYVTQDVIPCLTPSPLDLARYRDVVLERFGNPYVLDTNQRVAADGF
ECCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCEEEECCCCHHHCCH
SKIPGFIAPTLAESFARGASPIATAVLPALFLRFLERWARGALPYAYQDGVMDESAARAI
HHCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHCCCCCHHHHHHH
VGATDPVVALCANRQLWGSLAGNAALFEAIRGGLWRVDAWLAAR
HCCCCCHHHHHCCCHHHHHHCCHHHHHHHHHCCCEEEHHHHCCC
>Mature Secondary Structure 
SASPSARTPVLLHIGAGSFHRAHQAWYLHRVNAAVPADERWSLTVGNIRDDMHATMDAL
CCCCCCCCCEEEEECCCCHHHHHHHHHHEECCCCCCCCCCCEEEECCHHHHHHHHHHHH
AAQHGAYTLETVTPQGERAYETIRAITRVLPWSIDLAALIDAGADPDCRIVSFTVTEGGY
HHHCCCEEEEEECCCCHHHHHHHHHHHHHCCCCCCHHHHHCCCCCCCCEEEEEEEECCCE
YLDEHNRLDLANADLAADLQGARTTLYGALAALLAERVTRGAGPLTLQSCDNLRNNGARF
EECCCCCEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEHHHHHHHHCCCHHH
RAGMREFLERRGQADLLAWFDANVATPSAMVDRITPRPTADVRERVLAATGVDDACPVMG
HHHHHHHHHHCCCCCEEEEECCCCCCHHHHHHCCCCCCCHHHHHHHHHHCCCCCCCHHHH
ESFIQWVIEDRFAAGRPRWELAGAELVDDVHPYEEAKIRILNATHSCIAWAGTLAGHTYI
HHHHHHHHHHHHHCCCCCCEECCHHHHHHCCCCCCCEEEEEECCHHHHHHHHHHHCCCEE
HEGTHDAAIRRFAHDYVTQDVIPCLTPSPLDLARYRDVVLERFGNPYVLDTNQRVAADGF
ECCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCEEEECCCCHHHCCH
SKIPGFIAPTLAESFARGASPIATAVLPALFLRFLERWARGALPYAYQDGVMDESAARAI
HHCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHCCCCCHHHHHHH
VGATDPVVALCANRQLWGSLAGNAALFEAIRGGLWRVDAWLAAR
HCCCCCHHHHHCCCHHHHHHCCHHHHHHHHHCCCEEEHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11823852 [H]