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The map label for this gene is iorB [H]

Identifier: 77458671

GI number: 77458671

Start: 2798070

End: 2800307

Strand: Reverse

Name: iorB [H]

Synonym: Pfl01_2446

Alternate gene names: 77458671

Gene position: 2800307-2798070 (Counterclockwise)

Preceding gene: 77458672

Following gene: 77458670

Centisome position: 43.49

GC content: 65.64

Gene sequence:

>2238_bases
ATGACGACGATCAATGAGGTCGATCACAGTCGCCGTGCGTTCCTGCGCGGGGGCGCTCTGCTGGTAGCGTTTGCTTTGGT
GCCGGTCTCGCGCCGCGCCCTGGCTGACACCGAAGTCGACACTTTGGGCACTGTCGTGCTGGCGCCGGACCTGCCCGGCA
GCCTGCGCACCAACCCTTGGCTCGATGCGTGGATCCGCGTCGGCCCCGACGGCATCACCGTCTACACCGGCAAGGTCGAA
CTGGGCACCGGGGTCAAAACCGCGTTGCTGCAAATTGCCGCTGAACGGCTGGAGGTCTCCCCGACAGCGATCAACCTGCT
CACCGCCGACACCGCACTGACGCCGAACGAAGGCTACACCGCCGGCAGCCACACGATTTTCGACAGCGGCACCGCGCTGT
TCAACGCGGCGGCACAAGTGCGCGAGATGCTGCTCGAATCGGCCGGGCGCAGCTGGAACGTTGCGCCGGCACTGCTGACG
ACTCGCGACGGCAGCATTCTCGGCCCGACCGGCCAACGCATGTCCTACGCCGACGCCGTCCGGGATGTGGATCTGCACCG
CTATGCAACGTCCGAGTCACCCTCGATGCCGCCGGCGTCATTCAAGCTCATCGGCCATTCGCTGCCACGCCTGGACATTC
CGGGCAAAGTCAGCGGCGGCGCCGCGTTCGTGCAGGACATTCGCCTGCCGGGCATGCTCCATGCCCGGGTCATCCGCCCG
CCGCGTCCCGGCTGCACGCTGGACGCCATCGATATTGAATCGATCAAGGCGCTGTCCGGGGTGGTGCAGGTGATTCGCGA
CGGCAATTATCTGGCCGTGGTCGCGCGGGACGAATGGCAAGCGATCAAAGCCATGCGTCATGGATACGCCTCGGCGCGCT
GGAGCGGCGGACAGGCGATTCCCGAATCGCGCGACATCCATGCGCTCCTCAAGCGCCTGCCCTCGCGTCGTTATCCGATT
AGCCATGAAGGCACCCCACAAGGCGCGACCGACAACGAATATCGCGCCCGGGTGACCAAGCAATACCTGATGCACGGTTC
GATCGGTCCGTCCTGCGCCGTGGCCTGGTTCAAGGACGGCACCCTCAACGTCTGGACCCACACCCAGGGCGTGTATCCGC
TGCGTGCCGGGATCGCCGAAATGCTGCGGTTGCCGCCCGAGCGCGTGCGCTGCATCCACACCGAAGGTTCCGGCTGTTAC
GGCCATAACGGCGCGGACGATGCAGCAGCCGACGCGGCGTTGATTGCCATGCGCGTGCCGGGCACGCCGGTGCGGGTGCA
ATGGATGCGCGAGCAGGAAAACCTTTGGGAGCCGTACAGCTCGGCGATGGTCACCGAAGTGCAAGCCAACCTTGACGCAC
AGGGTCGGCTGCAGGACTGGAACTATGAGCTGTGGACCACGCCGCACAACGAACGCATCGTCAACGCCGGGCGCTTGCTG
CCCGCACGCCTGCTGGCCCGGCCGTTCGCCTCCGCACCTTCGGTGCCGATCGCTCAGCCCGAAGGCGACGGCGATCGCAA
CGCGGTGCCGCTGTACACCGTGGCCTCTTCGCGGATCGACATGAACTTCGTCACCGAAATGCCGTTCCGCACCTCGGCCA
TGCGCTCGCTGGGCGCCCACATCAACGTCTTCGCCATCGAAGCCTGCATCGACGAGCTGGCCGCCAAGGCCGGACTGGAT
CCGGTTGCCCTGCGCCTGGCGCACCTGACCGATCCTCGGGCACGGGCTGTTGTGGAAAAGGTTCGCGATGCCGTCGGCTG
GCCGCAAAAAAGCAGTGAACCCGGCGCAGGCCTTGGCTTCGCCTTCGCGCGTTACAAAAACATCATGGGTTACTGCGCCA
TTGCCGTGCGTTTGCGGGTGCATCCGCAGACCGGCGAAGTGCAGATCGATCACGTCGTGACCGCAGTGGACGTGGGCCAG
ATCGTCAGTCCCGATGGCCTGCGTAACCAGGTCGAGGGCGGGATCGTGCAGTCCACCAGCTGGACGCTGTATGAAAAGGT
CGCCTATGACGCCGGTGGCATCCGCAGCTACGACTGGAGCGGCTACCCGATCCTGCGCTTCTCGCAAGTACCCAAAAAGG
TCGACGTTCACCTGCTCGACCAGCCGGGGCAACCGTTTCTGGGGGCCGCCGAAATCGTCCAGGGCCCCATGGCGGCCGCC
ATCGGCAACGCCGTGGCGAATGCCACCGGCCGGCGTTGGCTCAACCTTCCGCTGACCCGCTCGCAACAGCCTTCCTGA

Upstream 100 bases:

>100_bases
CCATTCGCGAACACATGTCCGTCAACCTCTGCCGCTGCGGCACGCACTTGCGCATCATCGAGGCGATCAACCTTGTCGCC
CGGCAAAACGGGAGCGCGCT

Downstream 100 bases:

>100_bases
ACTGCGCCACGTTGCATTTCACGCAATGCAGCGTGGCGTCGCGTGTGGATTATCAAGCACCGGACAGCCGCTTAACGTAG
GGCCATCCGGTGTCGGGCCA

Product: twin-arginine translocation pathway signal protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 745; Mature: 744

Protein sequence:

>745_residues
MTTINEVDHSRRAFLRGGALLVAFALVPVSRRALADTEVDTLGTVVLAPDLPGSLRTNPWLDAWIRVGPDGITVYTGKVE
LGTGVKTALLQIAAERLEVSPTAINLLTADTALTPNEGYTAGSHTIFDSGTALFNAAAQVREMLLESAGRSWNVAPALLT
TRDGSILGPTGQRMSYADAVRDVDLHRYATSESPSMPPASFKLIGHSLPRLDIPGKVSGGAAFVQDIRLPGMLHARVIRP
PRPGCTLDAIDIESIKALSGVVQVIRDGNYLAVVARDEWQAIKAMRHGYASARWSGGQAIPESRDIHALLKRLPSRRYPI
SHEGTPQGATDNEYRARVTKQYLMHGSIGPSCAVAWFKDGTLNVWTHTQGVYPLRAGIAEMLRLPPERVRCIHTEGSGCY
GHNGADDAAADAALIAMRVPGTPVRVQWMREQENLWEPYSSAMVTEVQANLDAQGRLQDWNYELWTTPHNERIVNAGRLL
PARLLARPFASAPSVPIAQPEGDGDRNAVPLYTVASSRIDMNFVTEMPFRTSAMRSLGAHINVFAIEACIDELAAKAGLD
PVALRLAHLTDPRARAVVEKVRDAVGWPQKSSEPGAGLGFAFARYKNIMGYCAIAVRLRVHPQTGEVQIDHVVTAVDVGQ
IVSPDGLRNQVEGGIVQSTSWTLYEKVAYDAGGIRSYDWSGYPILRFSQVPKKVDVHLLDQPGQPFLGAAEIVQGPMAAA
IGNAVANATGRRWLNLPLTRSQQPS

Sequences:

>Translated_745_residues
MTTINEVDHSRRAFLRGGALLVAFALVPVSRRALADTEVDTLGTVVLAPDLPGSLRTNPWLDAWIRVGPDGITVYTGKVE
LGTGVKTALLQIAAERLEVSPTAINLLTADTALTPNEGYTAGSHTIFDSGTALFNAAAQVREMLLESAGRSWNVAPALLT
TRDGSILGPTGQRMSYADAVRDVDLHRYATSESPSMPPASFKLIGHSLPRLDIPGKVSGGAAFVQDIRLPGMLHARVIRP
PRPGCTLDAIDIESIKALSGVVQVIRDGNYLAVVARDEWQAIKAMRHGYASARWSGGQAIPESRDIHALLKRLPSRRYPI
SHEGTPQGATDNEYRARVTKQYLMHGSIGPSCAVAWFKDGTLNVWTHTQGVYPLRAGIAEMLRLPPERVRCIHTEGSGCY
GHNGADDAAADAALIAMRVPGTPVRVQWMREQENLWEPYSSAMVTEVQANLDAQGRLQDWNYELWTTPHNERIVNAGRLL
PARLLARPFASAPSVPIAQPEGDGDRNAVPLYTVASSRIDMNFVTEMPFRTSAMRSLGAHINVFAIEACIDELAAKAGLD
PVALRLAHLTDPRARAVVEKVRDAVGWPQKSSEPGAGLGFAFARYKNIMGYCAIAVRLRVHPQTGEVQIDHVVTAVDVGQ
IVSPDGLRNQVEGGIVQSTSWTLYEKVAYDAGGIRSYDWSGYPILRFSQVPKKVDVHLLDQPGQPFLGAAEIVQGPMAAA
IGNAVANATGRRWLNLPLTRSQQPS
>Mature_744_residues
TTINEVDHSRRAFLRGGALLVAFALVPVSRRALADTEVDTLGTVVLAPDLPGSLRTNPWLDAWIRVGPDGITVYTGKVEL
GTGVKTALLQIAAERLEVSPTAINLLTADTALTPNEGYTAGSHTIFDSGTALFNAAAQVREMLLESAGRSWNVAPALLTT
RDGSILGPTGQRMSYADAVRDVDLHRYATSESPSMPPASFKLIGHSLPRLDIPGKVSGGAAFVQDIRLPGMLHARVIRPP
RPGCTLDAIDIESIKALSGVVQVIRDGNYLAVVARDEWQAIKAMRHGYASARWSGGQAIPESRDIHALLKRLPSRRYPIS
HEGTPQGATDNEYRARVTKQYLMHGSIGPSCAVAWFKDGTLNVWTHTQGVYPLRAGIAEMLRLPPERVRCIHTEGSGCYG
HNGADDAAADAALIAMRVPGTPVRVQWMREQENLWEPYSSAMVTEVQANLDAQGRLQDWNYELWTTPHNERIVNAGRLLP
ARLLARPFASAPSVPIAQPEGDGDRNAVPLYTVASSRIDMNFVTEMPFRTSAMRSLGAHINVFAIEACIDELAAKAGLDP
VALRLAHLTDPRARAVVEKVRDAVGWPQKSSEPGAGLGFAFARYKNIMGYCAIAVRLRVHPQTGEVQIDHVVTAVDVGQI
VSPDGLRNQVEGGIVQSTSWTLYEKVAYDAGGIRSYDWSGYPILRFSQVPKKVDVHLLDQPGQPFLGAAEIVQGPMAAAI
GNAVANATGRRWLNLPLTRSQQPS

Specific function: Specific towards N-containing N-heterocyclic substrates, including isoquinoline, isoquinolin-5-ol, phthalazine and quinazoline [H]

COG id: COG1529

COG function: function code C; Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000674
- InterPro:   IPR008274
- InterPro:   IPR012368
- InterPro:   IPR006311 [H]

Pfam domain/function: PF02738 Ald_Xan_dh_C2 [H]

EC number: =1.3.99.16 [H]

Molecular weight: Translated: 80682; Mature: 80551

Theoretical pI: Translated: 7.94; Mature: 7.94

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTINEVDHSRRAFLRGGALLVAFALVPVSRRALADTEVDTLGTVVLAPDLPGSLRTNPW
CCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCHHHCEEEEECCCCCCCCCCCCC
LDAWIRVGPDGITVYTGKVELGTGVKTALLQIAAERLEVSPTAINLLTADTALTPNEGYT
CEEHEEECCCCEEEEEEEEEECCCHHHHHHHHHHHHHCCCCCEEEEEEECCEECCCCCCC
AGSHTIFDSGTALFNAAAQVREMLLESAGRSWNVAPALLTTRDGSILGPTGQRMSYADAV
CCCCEEECCCHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCEECCCCCCCHHHHHH
RDVDLHRYATSESPSMPPASFKLIGHSLPRLDIPGKVSGGAAFVQDIRLPGMLHARVIRP
HHCHHHHHCCCCCCCCCCHHHHHHCCCCCCCCCCCCCCCCHHHHHHHCCCCCEEEEEECC
PRPGCTLDAIDIESIKALSGVVQVIRDGNYLAVVARDEWQAIKAMRHGYASARWSGGQAI
CCCCCEEEECCHHHHHHHHHHHHHHHCCCEEEEEECCHHHHHHHHHCCCCCCCCCCCCCC
PESRDIHALLKRLPSRRYPISHEGTPQGATDNEYRARVTKQYLMHGSIGPSCAVAWFKDG
CCCCCHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCEEEEEEECC
TLNVWTHTQGVYPLRAGIAEMLRLPPERVRCIHTEGSGCYGHNGADDAAADAALIAMRVP
EEEEEEECCCCCHHHHHHHHHHHCCHHHEEEEEECCCCCCCCCCCCCHHCCEEEEEEECC
GTPVRVQWMREQENLWEPYSSAMVTEVQANLDAQGRLQDWNYELWTTPHNERIVNAGRLL
CCCEEEEEEHHHHHHCCHHHHHHHHHHHHCCCCCCCEECCCEEEEECCCCCEEECCCCCH
PARLLARPFASAPSVPIAQPEGDGDRNAVPLYTVASSRIDMNFVTEMPFRTSAMRSLGAH
HHHHHHHHCCCCCCCCCCCCCCCCCCCCEEEEEEECCCCCEEEEECCCCHHHHHHHHCCC
INVFAIEACIDELAAKAGLDPVALRLAHLTDPRARAVVEKVRDAVGWPQKSSEPGAGLGF
EEEEEHHHHHHHHHHHCCCCHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCCCCCCHHH
AFARYKNIMGYCAIAVRLRVHPQTGEVQIDHVVTAVDVGQIVSPDGLRNQVEGGIVQSTS
HHHHHHHHHHEEEEEEEEEECCCCCCEEEEEEEEEECCCCCCCCCCCHHHHCCCEEECCC
WTLYEKVAYDAGGIRSYDWSGYPILRFSQVPKKVDVHLLDQPGQPFLGAAEIVQGPMAAA
CHHHHHHHHCCCCCCCCCCCCCCEEECCCCCCEECEEEECCCCCCCCCHHHHHCCHHHHH
IGNAVANATGRRWLNLPLTRSQQPS
HHHHHHHCCCCEEEECCCCCCCCCC
>Mature Secondary Structure 
TTINEVDHSRRAFLRGGALLVAFALVPVSRRALADTEVDTLGTVVLAPDLPGSLRTNPW
CCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCHHHCEEEEECCCCCCCCCCCCC
LDAWIRVGPDGITVYTGKVELGTGVKTALLQIAAERLEVSPTAINLLTADTALTPNEGYT
CEEHEEECCCCEEEEEEEEEECCCHHHHHHHHHHHHHCCCCCEEEEEEECCEECCCCCCC
AGSHTIFDSGTALFNAAAQVREMLLESAGRSWNVAPALLTTRDGSILGPTGQRMSYADAV
CCCCEEECCCHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCEECCCCCCCHHHHHH
RDVDLHRYATSESPSMPPASFKLIGHSLPRLDIPGKVSGGAAFVQDIRLPGMLHARVIRP
HHCHHHHHCCCCCCCCCCHHHHHHCCCCCCCCCCCCCCCCHHHHHHHCCCCCEEEEEECC
PRPGCTLDAIDIESIKALSGVVQVIRDGNYLAVVARDEWQAIKAMRHGYASARWSGGQAI
CCCCCEEEECCHHHHHHHHHHHHHHHCCCEEEEEECCHHHHHHHHHCCCCCCCCCCCCCC
PESRDIHALLKRLPSRRYPISHEGTPQGATDNEYRARVTKQYLMHGSIGPSCAVAWFKDG
CCCCCHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCEEEEEEECC
TLNVWTHTQGVYPLRAGIAEMLRLPPERVRCIHTEGSGCYGHNGADDAAADAALIAMRVP
EEEEEEECCCCCHHHHHHHHHHHCCHHHEEEEEECCCCCCCCCCCCCHHCCEEEEEEECC
GTPVRVQWMREQENLWEPYSSAMVTEVQANLDAQGRLQDWNYELWTTPHNERIVNAGRLL
CCCEEEEEEHHHHHHCCHHHHHHHHHHHHCCCCCCCEECCCEEEEECCCCCEEECCCCCH
PARLLARPFASAPSVPIAQPEGDGDRNAVPLYTVASSRIDMNFVTEMPFRTSAMRSLGAH
HHHHHHHHCCCCCCCCCCCCCCCCCCCCEEEEEEECCCCCEEEEECCCCHHHHHHHHCCC
INVFAIEACIDELAAKAGLDPVALRLAHLTDPRARAVVEKVRDAVGWPQKSSEPGAGLGF
EEEEEHHHHHHHHHHHCCCCHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCCCCCCHHH
AFARYKNIMGYCAIAVRLRVHPQTGEVQIDHVVTAVDVGQIVSPDGLRNQVEGGIVQSTS
HHHHHHHHHHEEEEEEEEEECCCCCCEEEEEEEEEECCCCCCCCCCCHHHHCCCEEECCC
WTLYEKVAYDAGGIRSYDWSGYPILRFSQVPKKVDVHLLDQPGQPFLGAAEIVQGPMAAA
CHHHHHHHHCCCCCCCCCCCCCCEEECCCCCCEECEEEECCCCCCCCCHHHHHCCHHHHH
IGNAVANATGRRWLNLPLTRSQQPS
HHHHHHHCCCCEEEECCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7782304; 8157655 [H]