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The map label for this gene is iorA [H]

Identifier: 77458672

GI number: 77458672

Start: 2800304

End: 2800777

Strand: Reverse

Name: iorA [H]

Synonym: Pfl01_2447

Alternate gene names: 77458672

Gene position: 2800777-2800304 (Counterclockwise)

Preceding gene: 77458673

Following gene: 77458671

Centisome position: 43.5

GC content: 61.39

Gene sequence:

>474_bases
ATGACTCAGATCACCCTCAACGTCAACGGATCCACCCAGGCTCTCGAACTGGAGCCCGACATGCCGCTGCTCTATGCGCT
GCGCAATCACCTGGGCCTGAACGGCGCCAAGTACGGCTGTGGTCTGGGCCAATGCGGTGCCTGCACCGTCATCGTCGATG
ACCAACCGGTGTTTTCCTGCCTGACACCCTGCGCCGGTCTCGAAGGCAAAAAGGTTCGGACGGTCGAGAGTCTGGGAACC
GCCGAACACCCCGGCTCTCTGCAGCAAGCGTTCATCGACAAGCAGGCCGCTCAATGCGGTTATTGCATCGCCGGCATGTT
GATGCGTGCGCAGTCTCTGCTGGAACGCAATCCGCACCCCGACGAGCAGACCATTCGCGAACACATGTCCGTCAACCTCT
GCCGCTGCGGCACGCACTTGCGCATCATCGAGGCGATCAACCTTGTCGCCCGGCAAAACGGGAGCGCGCTATGA

Upstream 100 bases:

>100_bases
AACTCGACGCCCTGGCCGTCTACCTGCGCCATCAGGCCAGCCCCGACCAACCGTGGACCGACCTTCCTGCCACCCTCCAA
GCGCTACGTCAGGAGACGAA

Downstream 100 bases:

>100_bases
CGACGATCAATGAGGTCGATCACAGTCGCCGTGCGTTCCTGCGCGGGGGCGCTCTGCTGGTAGCGTTTGCTTTGGTGCCG
GTCTCGCGCCGCGCCCTGGC

Product: ferredoxin

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 157; Mature: 156

Protein sequence:

>157_residues
MTQITLNVNGSTQALELEPDMPLLYALRNHLGLNGAKYGCGLGQCGACTVIVDDQPVFSCLTPCAGLEGKKVRTVESLGT
AEHPGSLQQAFIDKQAAQCGYCIAGMLMRAQSLLERNPHPDEQTIREHMSVNLCRCGTHLRIIEAINLVARQNGSAL

Sequences:

>Translated_157_residues
MTQITLNVNGSTQALELEPDMPLLYALRNHLGLNGAKYGCGLGQCGACTVIVDDQPVFSCLTPCAGLEGKKVRTVESLGT
AEHPGSLQQAFIDKQAAQCGYCIAGMLMRAQSLLERNPHPDEQTIREHMSVNLCRCGTHLRIIEAINLVARQNGSAL
>Mature_156_residues
TQITLNVNGSTQALELEPDMPLLYALRNHLGLNGAKYGCGLGQCGACTVIVDDQPVFSCLTPCAGLEGKKVRTVESLGTA
EHPGSLQQAFIDKQAAQCGYCIAGMLMRAQSLLERNPHPDEQTIREHMSVNLCRCGTHLRIIEAINLVARQNGSAL

Specific function: Specific towards N-containing N-heterocyclic substrates, including isoquinoline, isoquinolin-5-ol, phthalazine and quinazoline [H]

COG id: COG2080

COG function: function code C; Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 2Fe-2S ferredoxin-type domain [H]

Homologues:

Organism=Homo sapiens, GI91823271, Length=147, Percent_Identity=34.6938775510204, Blast_Score=68, Evalue=4e-12,
Organism=Escherichia coli, GI1786480, Length=162, Percent_Identity=37.6543209876543, Blast_Score=106, Evalue=6e-25,
Organism=Escherichia coli, GI1789232, Length=148, Percent_Identity=36.4864864864865, Blast_Score=89, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI32566215, Length=165, Percent_Identity=36.3636363636364, Blast_Score=103, Evalue=5e-23,
Organism=Caenorhabditis elegans, GI17539860, Length=156, Percent_Identity=37.8205128205128, Blast_Score=102, Evalue=7e-23,
Organism=Caenorhabditis elegans, GI17540638, Length=157, Percent_Identity=35.6687898089172, Blast_Score=98, Evalue=2e-21,
Organism=Drosophila melanogaster, GI17737937, Length=164, Percent_Identity=33.5365853658537, Blast_Score=78, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24647197, Length=164, Percent_Identity=33.5365853658537, Blast_Score=68, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24647195, Length=164, Percent_Identity=33.5365853658537, Blast_Score=68, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24647201, Length=162, Percent_Identity=33.3333333333333, Blast_Score=64, Evalue=4e-11,
Organism=Drosophila melanogaster, GI24647199, Length=166, Percent_Identity=31.3253012048193, Blast_Score=64, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002888
- InterPro:   IPR006058
- InterPro:   IPR012675
- InterPro:   IPR001041 [H]

Pfam domain/function: PF00111 Fer2; PF01799 Fer2_2 [H]

EC number: =1.3.99.16 [H]

Molecular weight: Translated: 16906; Mature: 16775

Theoretical pI: Translated: 6.64; Mature: 6.64

Prosite motif: PS00197 2FE2S_FER_1 ; PS51085 2FE2S_FER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

5.7 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
8.9 %Cys+Met (Translated Protein)
5.8 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
8.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTQITLNVNGSTQALELEPDMPLLYALRNHLGLNGAKYGCGLGQCGACTVIVDDQPVFSC
CCEEEEEECCCCEEEEECCCCHHHHHHHHHCCCCCCCCCCCCCCCCEEEEEECCCHHHHH
LTPCAGLEGKKVRTVESLGTAEHPGSLQQAFIDKQAAQCGYCIAGMLMRAQSLLERNPHP
HHHCCCCCCCEEHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
DEQTIREHMSVNLCRCGTHLRIIEAINLVARQNGSAL
CHHHHHHHHCCCHHHCCCHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure 
TQITLNVNGSTQALELEPDMPLLYALRNHLGLNGAKYGCGLGQCGACTVIVDDQPVFSC
CEEEEEECCCCEEEEECCCCHHHHHHHHHCCCCCCCCCCCCCCCCEEEEEECCCHHHHH
LTPCAGLEGKKVRTVESLGTAEHPGSLQQAFIDKQAAQCGYCIAGMLMRAQSLLERNPHP
HHHCCCCCCCEEHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
DEQTIREHMSVNLCRCGTHLRIIEAINLVARQNGSAL
CHHHHHHHHCCCHHHCCCHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7782304; 8157655 [H]