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The map label for this gene is lnt [H]

Identifier: 74318602

GI number: 74318602

Start: 2659209

End: 2660771

Strand: Direct

Name: lnt [H]

Synonym: Tbd_2584

Alternate gene names: 74318602

Gene position: 2659209-2660771 (Clockwise)

Preceding gene: 74318601

Following gene: 74318606

Centisome position: 91.39

GC content: 69.29

Gene sequence:

>1563_bases
TTGAGTCGGCGCGCTGAGGTCTTCGCCGGCACCGCGCCCGCCCTCCCGCGCCGCCTGCCGTTCGCGCAACTGCTGATCCC
GCTTATCGCCGGCGTGGCGGCAGTCGCGGGTTTTGCGCCCTTCGGCCTGTGGCCGCTGCCGATCCTCAGCCTCGCCGTGC
TCTTCGTCATGCTCGAACGCGCGCCCTCGCTGCGCGCGGGCTTGGCGCTGGGCTTCGCATGGGGACTCGGTTTTTTCCTC
ACCGGCGTGAGCTGGGTCTACGTCAGCCTCTCCGTCTACGGCGGTATGCCGGCATGGCTCGCGGGTCTGGCAACGTTCCT
GTTCTGCGGGTTTCTCGCGCTCTTTCCGGCGGCGGTCGGTGGTTTGCACGCGCGCCTTCGGGGGCATCAACGCACGCCGC
TTGCACCCGTCGTGCGCCTCCTGGTCCTGCTCCCGATGCTGTGGGGCGCGAGCGAATGGGTGCGCGGCTGGATTTTCACC
GGCTTCCCTTGGCTGGTCGTCGGCTATTCCCAAGTTCCCGCGAGTCCGCTCGCCGGCTACGCGCCGCTCACCGGCGTGTA
CGGCGTGTCATTCGTGCTGGCGTCGCTTGCCGCACTGCTGACCTGGCTGCTCACGCCGGGGCGAAGGCTGGCGGCGCGCG
CATGGGCGCTGGGGGCGATCGCGGTGGCGCTGTTTGGCGGGCAGCTTTTACGCGGCGTCGCGTGGACGACGCCGGACGGC
GGGCCGACTTCGGTCGCGCTGCTGCAAGGCAACGTCCCCCAGGCGATGAAATGGCAGCCCGAGCGCACGCTTCCCACGCT
CGAAACCTATCTGCGGATGGCGGCGGCCTCCCCGGCACGTCTGATCGTGCTGCCCGAGACCGCGCTGCCGCTGTTCGAAT
CCGATCTGCCCGAGCGCTACCGCGAGCGGCTCGCCGAGCTCGGCAGGGCCAATGGCGGCGACGTGCTCGCCGGCCTGCCG
ACCGGCTCCTACGAGCACGGCTACTACAACAGCGTGATCAGCCTCGGCAGCGCGCCCGGGCAGCGCTACCACAAGATTCA
CCTGGTGCCGTTCGGCGAATACATTCCGCTCAGGGCACTGTGGGGCTGGGTCGTCGAGGTGCTGCACATTCCGCTGTCGG
ATTTCTCGCGCGGCGGGGTCGAGCAGCGCCCGCTCGCGATCGGCGGCCAGCGCGTCGCGGCAGACATCTGCTATGAGGAC
GCTTTCGGCGAGGAAATCATCCGCCAGCTGCCGGAAGCGAGCGTGCTCGTGAACGTGAGCAACCTCGCCTGGTTCGGCGA
CTCGTTCGCGCCGTGGCAGCACGTGCAGATGTCGCAGATGCGGGCGCTCGAGAGCGGACGCATGATGCTGCGCGCGACCA
ATACCGGGGTCACGGCGATCATCGATGCACGCGGAAACCTGCTCGCCAGCCTGCCCCTGTTCACGGCCGGCAGCCTGACC
GGCGAAATCCAGGGCTATGCGGGGAGCACACCGTATGTGCGCTGGGGCAACGCGCCGGTGCTCGCGCTATGGGGCGTGAT
CGGGGTCGGGCTCCTCGCCCTTCGATTCAGGCGCTCGCCCTGA

Upstream 100 bases:

>100_bases
ACCTCGAAAAGTCTTGCGAGCCAGGGCGACAACACGCCCTTCCTCAACCACCCGATGCAAGGGCGCGTGCGCTATACCCT
GATCGACGGACATATCGATT

Downstream 100 bases:

>100_bases
CGCGGGTCGCGTTGCGGCCGCCGCGCTTGGCTTCGAGCAAGGCCGCGTCGGCGCGCGCGAGCGCCTCATTCTCGCCCCCG
TCATCACGGCTGTATTCGGA

Product: apolipoprotein N-acyltransferase

Products: NA

Alternate protein names: ALP N-acyltransferase [H]

Number of amino acids: Translated: 520; Mature: 519

Protein sequence:

>520_residues
MSRRAEVFAGTAPALPRRLPFAQLLIPLIAGVAAVAGFAPFGLWPLPILSLAVLFVMLERAPSLRAGLALGFAWGLGFFL
TGVSWVYVSLSVYGGMPAWLAGLATFLFCGFLALFPAAVGGLHARLRGHQRTPLAPVVRLLVLLPMLWGASEWVRGWIFT
GFPWLVVGYSQVPASPLAGYAPLTGVYGVSFVLASLAALLTWLLTPGRRLAARAWALGAIAVALFGGQLLRGVAWTTPDG
GPTSVALLQGNVPQAMKWQPERTLPTLETYLRMAAASPARLIVLPETALPLFESDLPERYRERLAELGRANGGDVLAGLP
TGSYEHGYYNSVISLGSAPGQRYHKIHLVPFGEYIPLRALWGWVVEVLHIPLSDFSRGGVEQRPLAIGGQRVAADICYED
AFGEEIIRQLPEASVLVNVSNLAWFGDSFAPWQHVQMSQMRALESGRMMLRATNTGVTAIIDARGNLLASLPLFTAGSLT
GEIQGYAGSTPYVRWGNAPVLALWGVIGVGLLALRFRRSP

Sequences:

>Translated_520_residues
MSRRAEVFAGTAPALPRRLPFAQLLIPLIAGVAAVAGFAPFGLWPLPILSLAVLFVMLERAPSLRAGLALGFAWGLGFFL
TGVSWVYVSLSVYGGMPAWLAGLATFLFCGFLALFPAAVGGLHARLRGHQRTPLAPVVRLLVLLPMLWGASEWVRGWIFT
GFPWLVVGYSQVPASPLAGYAPLTGVYGVSFVLASLAALLTWLLTPGRRLAARAWALGAIAVALFGGQLLRGVAWTTPDG
GPTSVALLQGNVPQAMKWQPERTLPTLETYLRMAAASPARLIVLPETALPLFESDLPERYRERLAELGRANGGDVLAGLP
TGSYEHGYYNSVISLGSAPGQRYHKIHLVPFGEYIPLRALWGWVVEVLHIPLSDFSRGGVEQRPLAIGGQRVAADICYED
AFGEEIIRQLPEASVLVNVSNLAWFGDSFAPWQHVQMSQMRALESGRMMLRATNTGVTAIIDARGNLLASLPLFTAGSLT
GEIQGYAGSTPYVRWGNAPVLALWGVIGVGLLALRFRRSP
>Mature_519_residues
SRRAEVFAGTAPALPRRLPFAQLLIPLIAGVAAVAGFAPFGLWPLPILSLAVLFVMLERAPSLRAGLALGFAWGLGFFLT
GVSWVYVSLSVYGGMPAWLAGLATFLFCGFLALFPAAVGGLHARLRGHQRTPLAPVVRLLVLLPMLWGASEWVRGWIFTG
FPWLVVGYSQVPASPLAGYAPLTGVYGVSFVLASLAALLTWLLTPGRRLAARAWALGAIAVALFGGQLLRGVAWTTPDGG
PTSVALLQGNVPQAMKWQPERTLPTLETYLRMAAASPARLIVLPETALPLFESDLPERYRERLAELGRANGGDVLAGLPT
GSYEHGYYNSVISLGSAPGQRYHKIHLVPFGEYIPLRALWGWVVEVLHIPLSDFSRGGVEQRPLAIGGQRVAADICYEDA
FGEEIIRQLPEASVLVNVSNLAWFGDSFAPWQHVQMSQMRALESGRMMLRATNTGVTAIIDARGNLLASLPLFTAGSLTG
EIQGYAGSTPYVRWGNAPVLALWGVIGVGLLALRFRRSP

Specific function: Transfers the fatty acyl group on membrane lipoproteins [H]

COG id: COG0815

COG function: function code M; Apolipoprotein N-acyltransferase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 CN hydrolase domain [H]

Homologues:

Organism=Escherichia coli, GI1786878, Length=515, Percent_Identity=37.0873786407767, Blast_Score=303, Evalue=2e-83,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004563
- InterPro:   IPR003010 [H]

Pfam domain/function: PF00795 CN_hydrolase [H]

EC number: 2.3.1.- [C]

Molecular weight: Translated: 55907; Mature: 55776

Theoretical pI: Translated: 10.01; Mature: 10.01

Prosite motif: PS50263 CN_HYDROLASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRRAEVFAGTAPALPRRLPFAQLLIPLIAGVAAVAGFAPFGLWPLPILSLAVLFVMLER
CCCCCCEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHC
APSLRAGLALGFAWGLGFFLTGVSWVYVSLSVYGGMPAWLAGLATFLFCGFLALFPAAVG
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHH
GLHARLRGHQRTPLAPVVRLLVLLPMLWGASEWVRGWIFTGFPWLVVGYSQVPASPLAGY
HHHHHHCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHCCCHHHEEECHHCCCCCCCCC
APLTGVYGVSFVLASLAALLTWLLTPGRRLAARAWALGAIAVALFGGQLLRGVAWTTPDG
CHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCEEECCCC
GPTSVALLQGNVPQAMKWQPERTLPTLETYLRMAAASPARLIVLPETALPLFESDLPERY
CCCEEEEEECCCCHHHCCCCCCCCHHHHHHHHHHHCCCCEEEEECCCCCHHHHCCCHHHH
RERLAELGRANGGDVLAGLPTGSYEHGYYNSVISLGSAPGQRYHKIHLVPFGEYIPLRAL
HHHHHHHHCCCCCCEEEECCCCCCCCCHHHHHHHCCCCCCCCEEEEEEEECCCCCHHHHH
WGWVVEVLHIPLSDFSRGGVEQRPLAIGGQRVAADICYEDAFGEEIIRQLPEASVLVNVS
HHHHHHHHHCCHHHHCCCCCCCCCEEECCHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEH
NLAWFGDSFAPWQHVQMSQMRALESGRMMLRATNTGVTAIIDARGNLLASLPLFTAGSLT
HHEECCCCCCCHHHHHHHHHHHHHCCCEEEEEECCCEEEEEECCCCEEECCCHHCCCCCC
GEIQGYAGSTPYVRWGNAPVLALWGVIGVGLLALRFRRSP
CEECCCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
SRRAEVFAGTAPALPRRLPFAQLLIPLIAGVAAVAGFAPFGLWPLPILSLAVLFVMLER
CCCCCEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHC
APSLRAGLALGFAWGLGFFLTGVSWVYVSLSVYGGMPAWLAGLATFLFCGFLALFPAAVG
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHH
GLHARLRGHQRTPLAPVVRLLVLLPMLWGASEWVRGWIFTGFPWLVVGYSQVPASPLAGY
HHHHHHCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHCCCHHHEEECHHCCCCCCCCC
APLTGVYGVSFVLASLAALLTWLLTPGRRLAARAWALGAIAVALFGGQLLRGVAWTTPDG
CHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCEEECCCC
GPTSVALLQGNVPQAMKWQPERTLPTLETYLRMAAASPARLIVLPETALPLFESDLPERY
CCCEEEEEECCCCHHHCCCCCCCCHHHHHHHHHHHCCCCEEEEECCCCCHHHHCCCHHHH
RERLAELGRANGGDVLAGLPTGSYEHGYYNSVISLGSAPGQRYHKIHLVPFGEYIPLRAL
HHHHHHHHCCCCCCEEEECCCCCCCCCHHHHHHHCCCCCCCCEEEEEEEECCCCCHHHHH
WGWVVEVLHIPLSDFSRGGVEQRPLAIGGQRVAADICYEDAFGEEIIRQLPEASVLVNVS
HHHHHHHHHCCHHHHCCCCCCCCCEEECCHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEH
NLAWFGDSFAPWQHVQMSQMRALESGRMMLRATNTGVTAIIDARGNLLASLPLFTAGSLT
HHEECCCCCCCHHHHHHHHHHHHHCCCEEEEEECCCEEEEEECCCCEEECCCHHCCCCCC
GEIQGYAGSTPYVRWGNAPVLALWGVIGVGLLALRFRRSP
CEECCCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Transferases; Acyltransferases; Transferring groups other than amino-acyl groups [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12700255 [H]