Click here to switch to the map view.

The map label for this gene is radC [C]

Identifier: 74318606

GI number: 74318606

Start: 2664044

End: 2664718

Strand: Direct

Name: radC [C]

Synonym: Tbd_2588

Alternate gene names: 74318606

Gene position: 2664044-2664718 (Clockwise)

Preceding gene: 74318602

Following gene: 74318607

Centisome position: 91.55

GC content: 68.89

Gene sequence:

>675_bases
ATGGCGATTCGCGACTGGCCGGAGGACGCGCGTCCGCGCGAGAAGCTCCTGAAACAGGGCGCGGCGGCGCTGACCGATGC
GGAACTGGTCGCGGTATTCCTGCGCACCGGGGTCGCCGGCAAGAGCGCGGTCGATCTCGGACGGGATCTGATCGAGCGTT
TCGGAGGTCTCGGCGCGCTGTGCCGCGCCGACCGGGTCGCGGCCTGCCGGGCGCCCGGCGTCGGTGAGGCGAAATACGCC
CTGCTCCAGGCCGTGATGGAAATGGCCCGCCGCACGCTGGCCGAGGACATGCAGGCCGGCGACGCCCTGTCATCCCCCGC
GGCCGTGCGCGACTACCTGCGGCTGATCCTGCGCGACAAGGAATACGAGGTCTTCTGCTGCGTGTTTCTCAACGCGCAAA
ATCGCGTGATCGCGGTCGAGGAACTGTTTCGCGGCACGCTCACGCAGACCAGCGTCTATCCGCGGGAAATCGTCAAACGC
GCGCTCGCGCACAACGCCGCGGCGATGATTCTCGCGCACAACCACCCGAGCGGGGTCAACGAGCCGAGTCAGGCCGACCG
CTCGCTGACCCGTCGGCTCGCCGAGGCCCTGGCGCTCGTCGACATCCGCGTGCTCGACCATTTCATCATCGCCGGCGCCT
CGGCGCTCTCGTTCGCCGAGGCCGGTCATCTCTGA

Upstream 100 bases:

>100_bases
CGTCACCCCGAGAACGATTTTTTTGTCTGCTAGCGACACGGCTCGATTCCCAGCGCGCTTTCCATGAAAATGCTCGCATT
CTACGGGAGGGGGCAAGGGG

Downstream 100 bases:

>100_bases
GCCGGGCGGCTTGCCCGCGCGTTGGGAACTGTGGTATAAATCGCGGTTCTCGGGTTGACCCTCTGCGTTAACCCCACCGG
TTAACCCTCAATTTCTGGAG

Product: DNA repair protein RadC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 224; Mature: 223

Protein sequence:

>224_residues
MAIRDWPEDARPREKLLKQGAAALTDAELVAVFLRTGVAGKSAVDLGRDLIERFGGLGALCRADRVAACRAPGVGEAKYA
LLQAVMEMARRTLAEDMQAGDALSSPAAVRDYLRLILRDKEYEVFCCVFLNAQNRVIAVEELFRGTLTQTSVYPREIVKR
ALAHNAAAMILAHNHPSGVNEPSQADRSLTRRLAEALALVDIRVLDHFIIAGASALSFAEAGHL

Sequences:

>Translated_224_residues
MAIRDWPEDARPREKLLKQGAAALTDAELVAVFLRTGVAGKSAVDLGRDLIERFGGLGALCRADRVAACRAPGVGEAKYA
LLQAVMEMARRTLAEDMQAGDALSSPAAVRDYLRLILRDKEYEVFCCVFLNAQNRVIAVEELFRGTLTQTSVYPREIVKR
ALAHNAAAMILAHNHPSGVNEPSQADRSLTRRLAEALALVDIRVLDHFIIAGASALSFAEAGHL
>Mature_223_residues
AIRDWPEDARPREKLLKQGAAALTDAELVAVFLRTGVAGKSAVDLGRDLIERFGGLGALCRADRVAACRAPGVGEAKYAL
LQAVMEMARRTLAEDMQAGDALSSPAAVRDYLRLILRDKEYEVFCCVFLNAQNRVIAVEELFRGTLTQTSVYPREIVKRA
LAHNAAAMILAHNHPSGVNEPSQADRSLTRRLAEALALVDIRVLDHFIIAGASALSFAEAGHL

Specific function: Involved In DNA Repair. [C]

COG id: COG2003

COG function: function code L; DNA repair proteins

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UPF0758 family

Homologues:

Organism=Escherichia coli, GI87082300, Length=211, Percent_Identity=45.0236966824645, Blast_Score=194, Evalue=3e-51,
Organism=Escherichia coli, GI1788997, Length=125, Percent_Identity=55.2, Blast_Score=142, Evalue=2e-35,
Organism=Escherichia coli, GI2367100, Length=125, Percent_Identity=56, Blast_Score=140, Evalue=8e-35,
Organism=Escherichia coli, GI1788312, Length=143, Percent_Identity=51.0489510489511, Blast_Score=139, Evalue=2e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): Y2588_THIDA (Q3SFR5)

Other databases:

- EMBL:   CP000116
- RefSeq:   YP_316346.1
- ProteinModelPortal:   Q3SFR5
- SMR:   Q3SFR5
- STRING:   Q3SFR5
- GeneID:   3672564
- GenomeReviews:   CP000116_GR
- KEGG:   tbd:Tbd_2588
- NMPDR:   fig|292415.3.peg.2660
- eggNOG:   COG2003
- HOGENOM:   HBG751042
- OMA:   GISKYTQ
- PhylomeDB:   Q3SFR5
- BioCyc:   TDEN292415:TBD_2588-MONOMER
- InterPro:   IPR010994
- InterPro:   IPR001405
- InterPro:   IPR020891
- TIGRFAMs:   TIGR00608

Pfam domain/function: PF04002 DUF2466; SSF47781 RuvA_2_like

EC number: NA

Molecular weight: Translated: 24304; Mature: 24173

Theoretical pI: Translated: 7.51; Mature: 7.51

Prosite motif: PS01302 UPF0758

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAIRDWPEDARPREKLLKQGAAALTDAELVAVFLRTGVAGKSAVDLGRDLIERFGGLGAL
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCHHH
CRADRVAACRAPGVGEAKYALLQAVMEMARRTLAEDMQAGDALSSPAAVRDYLRLILRDK
HHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCC
EYEVFCCVFLNAQNRVIAVEELFRGTLTQTSVYPREIVKRALAHNAAAMILAHNHPSGVN
CCEEEEEEEECCCCCEEEHHHHHHHHHHHCCCCHHHHHHHHHHCCHHEEEEEECCCCCCC
EPSQADRSLTRRLAEALALVDIRVLDHFIIAGASALSFAEAGHL
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
AIRDWPEDARPREKLLKQGAAALTDAELVAVFLRTGVAGKSAVDLGRDLIERFGGLGAL
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCHHH
CRADRVAACRAPGVGEAKYALLQAVMEMARRTLAEDMQAGDALSSPAAVRDYLRLILRDK
HHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCC
EYEVFCCVFLNAQNRVIAVEELFRGTLTQTSVYPREIVKRALAHNAAAMILAHNHPSGVN
CCEEEEEEEECCCCCEEEHHHHHHHHHHHCCCCHHHHHHHHHHCCHHEEEEEECCCCCCC
EPSQADRSLTRRLAEALALVDIRVLDHFIIAGASALSFAEAGHL
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA