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The map label for this gene is mrkC [H]

Identifier: 73540541

GI number: 73540541

Start: 905398

End: 907956

Strand: Reverse

Name: mrkC [H]

Synonym: Reut_A0838

Alternate gene names: 73540541

Gene position: 907956-905398 (Counterclockwise)

Preceding gene: 73540542

Following gene: 73540540

Centisome position: 23.85

GC content: 65.46

Gene sequence:

>2559_bases
ATGCAAAAAAGAACAGCGCACGCTATTCCGCCCAGCCTGCGGCCGCTCAGTGCCGTAGTCATGATGCTCGTCAGTGCCGG
CGCGCTCGGTGCAAACCCCGATCCACGCCCGGCGCCTTCGTCCGCCGAAGTGGAATTCAATGACCTGTTCCTGCACCAGC
CCGGCGGAAGCGCAGTCGATTTCAGCCGCTTCAACACGGGCAATGTCGTGCTGCCTGGCAACTACCGCGCGGAGCTTTAC
GTCAACCAGGCATGGCTCGGGCGGATGGAAGTCCGCATGGGCGAGACGGCGGGCAAGGATAGTCCGGTACTGCCTTGCTT
CGATGAGCCACTGCTTGTTCGGATCGGCGCGGATGCCAACAAGCTCACGCCGGAAGCGACGGCATCCGTGCAAGATCGCG
ACGCTTGCGTGCCGCTGCATGCCATCATCGCTGGTGCCACCGCGAGCTTCGACAGCAGCGAACAACGGCTCGATGTCAGC
GTGCCACAGGCCGCGCTGACGCGGCAGGCGCGCGGGTATGTGGATCCTCGGTACTGGAGCGACGGCGTAACCGCGGCGAC
GCTCCAGTACAACGGCAGCGTCTATCAGTCGCGCGCGGAAGCCCGTACGGCCACGCAAGGCTATCTGGGCCTCAATGCGG
GCTTCAATGCCGGCCCCTGGCGCTTCCGACACAAGGGCAGCCTCGGCGTCGATCAGGGCAACGCGCGGTACCAGAGCATA
CAGACCAGCTTGCAGCGCTCGGTCGTTGCGCTGCGCAGCCAACTGGTGCTCGGCGATGCTTTCACCGACGGTACCGTCTT
CGACAGCGTCGGCTTCCGTGGCGTCCAGCTCGCGAGCGACGACCGCATGCAACCGGAATCACAGCGCGGCTATGCACCGA
GCGTGCGCGGCATCGCCAACAGCAACGCGCGCGTACAGGTCCGCCAAAACGGCAACCTGATCTACGAAACCACGGTCGCG
GCCGGCCCGTTCGAGATCGACGACCTCTATCCGACCGGCTATGGCGGCGACCTGGAAGTCGTGGTGACCGAAGCCGACGG
CAGCGTGCATGTTTCGCGTGTCCCTTATGCGGCCGCTGTCAATGCCTTGCGTCCCGGCGTCACACGCTATGGCATCACCG
CAGGCCAATACCGCAATGCGGGCCTGCATGACCGTCCTGCCATGCTCCAGGCCACCGTACAGCACGGCTTCACCAATATG
GTGACCGGCTACGGTGGTGTCGTGGTGGCAGAAGGCTACCTCGCCGCAGCGGCTGGCGCCGCGCTCAACACGGTCTATGG
TGCGTTCGGTGCTGACCTGACCCATGCGGGCACGCGCCTCACCACGCAGCCGGACCGTCATGGCTTCAGCATGCGAATCA
GCTACAGCAAGCTCGTGGAGCCCACCGGCACCAACGTATCCGTCGCGGCCTATCGCTATTCGAGCAGCGGTTACCTCAGC
TTTGCCGATGCGATGACCCTGCGCGAACTCGAGCACGGCGCCATGCAATCGACGATGCGCGGCATCCCGCGCAGCCAGCT
CCAGCTCACCCTGAATCAACGCCTGCAGCCCGGCTACGGGTCCCTGTATCTGTCCGGGTCAGTACACGGCTACTGGAACC
GCAGAGGCACCGACACGCAGTTCCAGCTCGGCTACAACAACAGCTACAAGTCGCTGAACTATGGCGTTGCGGCATCGCGC
CAGTTCAGCGTGTCGAGCGGTCGCTGGGAAAGCCGCGTTATGCTCAATATCGGCATCCCGCTGGGCAAGGCCCGGCATGC
GCCGTATGCCATGACCGGCATCGAGCGCGATTCGTCCGGAGCGGTGAGCCTGCAGCAGTCAATGACTGGCTCGCTCGGCG
CCGACAACGCCTTCAGCTACGGCGTGAATGCCGGCTATGCCGGCGGTAGCGGCCGCCATGCTGCAAGCCTCGCGGGTAAT
GCGTCTTATCTGTCTCCCGTGGCTACGCTGACGGCAACTGCTGGCAAGGGCAGCAACTATTCGCAAGTGTCCGCGGGCAT
CTCGGGCGGCGTCGTGGCCTATGCCGGCGGCGTGGGCTTCACGCCGACGATGGGCGAGACGCTTGCCATCGTCGAAGCCG
CCGACGCTGGCGGAGCCCGGCTCGCCAACGGGAGCGGGCTGCGTATCGATCGCTGGGGCCACGCGGTGGTGCCCGGACTG
GTGCCGTTCTCGCGCAACCAGATCGAGATCGATCCGAAGGGCCTGCCGATGAACGTGGAGCTGGACTCCACGCTCCAGCA
GGTTGCCCCGACCGCAGGCGCCGTGGTGGCGGTCCGGTTCGCGACCGCGGATCGCGGACGGCCTGCGGTCATCCGCACCA
GCACGGCCGATGGCAAGTCGATTCCATTCGGCGCCGAAGTACAGGATGCTCACGGCAACAACATTGGCACCGTTGGACAA
GGCAGCCGCATCGTTGCGCGCGGCCTGCGGGCCGAACGTGGCCAGTTGACCGTGCGGTGGGGCAAGACGGCGCAAGACAG
CTGCCGACTCGACTATGTGCTGCCCGCCGCAGCGCGGCGCGATACGCGCATTGAGGTCATCGAGGCGCAGTGCCATTGA

Upstream 100 bases:

>100_bases
GGCACATGCCGGCCTCACTGAAATTCCCCTGATTCGCGCTGACGCATGCCGCTGGACGGCAGGGACGCGTGTTACCCCAA
TTTCCAGCGCAATACATGCC

Downstream 100 bases:

>100_bases
ACTGGCCCGCCGTTTCACCAAGAAATTGTCCATGGCACCGCGGCGGCAGGTGGCTACACTGTGAAGCTACCGCGCCTCCG
GATGCCGTCATGACCACCTA

Product: fimbrial biogenesis outer membrane usher protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 852; Mature: 852

Protein sequence:

>852_residues
MQKRTAHAIPPSLRPLSAVVMMLVSAGALGANPDPRPAPSSAEVEFNDLFLHQPGGSAVDFSRFNTGNVVLPGNYRAELY
VNQAWLGRMEVRMGETAGKDSPVLPCFDEPLLVRIGADANKLTPEATASVQDRDACVPLHAIIAGATASFDSSEQRLDVS
VPQAALTRQARGYVDPRYWSDGVTAATLQYNGSVYQSRAEARTATQGYLGLNAGFNAGPWRFRHKGSLGVDQGNARYQSI
QTSLQRSVVALRSQLVLGDAFTDGTVFDSVGFRGVQLASDDRMQPESQRGYAPSVRGIANSNARVQVRQNGNLIYETTVA
AGPFEIDDLYPTGYGGDLEVVVTEADGSVHVSRVPYAAAVNALRPGVTRYGITAGQYRNAGLHDRPAMLQATVQHGFTNM
VTGYGGVVVAEGYLAAAAGAALNTVYGAFGADLTHAGTRLTTQPDRHGFSMRISYSKLVEPTGTNVSVAAYRYSSSGYLS
FADAMTLRELEHGAMQSTMRGIPRSQLQLTLNQRLQPGYGSLYLSGSVHGYWNRRGTDTQFQLGYNNSYKSLNYGVAASR
QFSVSSGRWESRVMLNIGIPLGKARHAPYAMTGIERDSSGAVSLQQSMTGSLGADNAFSYGVNAGYAGGSGRHAASLAGN
ASYLSPVATLTATAGKGSNYSQVSAGISGGVVAYAGGVGFTPTMGETLAIVEAADAGGARLANGSGLRIDRWGHAVVPGL
VPFSRNQIEIDPKGLPMNVELDSTLQQVAPTAGAVVAVRFATADRGRPAVIRTSTADGKSIPFGAEVQDAHGNNIGTVGQ
GSRIVARGLRAERGQLTVRWGKTAQDSCRLDYVLPAAARRDTRIEVIEAQCH

Sequences:

>Translated_852_residues
MQKRTAHAIPPSLRPLSAVVMMLVSAGALGANPDPRPAPSSAEVEFNDLFLHQPGGSAVDFSRFNTGNVVLPGNYRAELY
VNQAWLGRMEVRMGETAGKDSPVLPCFDEPLLVRIGADANKLTPEATASVQDRDACVPLHAIIAGATASFDSSEQRLDVS
VPQAALTRQARGYVDPRYWSDGVTAATLQYNGSVYQSRAEARTATQGYLGLNAGFNAGPWRFRHKGSLGVDQGNARYQSI
QTSLQRSVVALRSQLVLGDAFTDGTVFDSVGFRGVQLASDDRMQPESQRGYAPSVRGIANSNARVQVRQNGNLIYETTVA
AGPFEIDDLYPTGYGGDLEVVVTEADGSVHVSRVPYAAAVNALRPGVTRYGITAGQYRNAGLHDRPAMLQATVQHGFTNM
VTGYGGVVVAEGYLAAAAGAALNTVYGAFGADLTHAGTRLTTQPDRHGFSMRISYSKLVEPTGTNVSVAAYRYSSSGYLS
FADAMTLRELEHGAMQSTMRGIPRSQLQLTLNQRLQPGYGSLYLSGSVHGYWNRRGTDTQFQLGYNNSYKSLNYGVAASR
QFSVSSGRWESRVMLNIGIPLGKARHAPYAMTGIERDSSGAVSLQQSMTGSLGADNAFSYGVNAGYAGGSGRHAASLAGN
ASYLSPVATLTATAGKGSNYSQVSAGISGGVVAYAGGVGFTPTMGETLAIVEAADAGGARLANGSGLRIDRWGHAVVPGL
VPFSRNQIEIDPKGLPMNVELDSTLQQVAPTAGAVVAVRFATADRGRPAVIRTSTADGKSIPFGAEVQDAHGNNIGTVGQ
GSRIVARGLRAERGQLTVRWGKTAQDSCRLDYVLPAAARRDTRIEVIEAQCH
>Mature_852_residues
MQKRTAHAIPPSLRPLSAVVMMLVSAGALGANPDPRPAPSSAEVEFNDLFLHQPGGSAVDFSRFNTGNVVLPGNYRAELY
VNQAWLGRMEVRMGETAGKDSPVLPCFDEPLLVRIGADANKLTPEATASVQDRDACVPLHAIIAGATASFDSSEQRLDVS
VPQAALTRQARGYVDPRYWSDGVTAATLQYNGSVYQSRAEARTATQGYLGLNAGFNAGPWRFRHKGSLGVDQGNARYQSI
QTSLQRSVVALRSQLVLGDAFTDGTVFDSVGFRGVQLASDDRMQPESQRGYAPSVRGIANSNARVQVRQNGNLIYETTVA
AGPFEIDDLYPTGYGGDLEVVVTEADGSVHVSRVPYAAAVNALRPGVTRYGITAGQYRNAGLHDRPAMLQATVQHGFTNM
VTGYGGVVVAEGYLAAAAGAALNTVYGAFGADLTHAGTRLTTQPDRHGFSMRISYSKLVEPTGTNVSVAAYRYSSSGYLS
FADAMTLRELEHGAMQSTMRGIPRSQLQLTLNQRLQPGYGSLYLSGSVHGYWNRRGTDTQFQLGYNNSYKSLNYGVAASR
QFSVSSGRWESRVMLNIGIPLGKARHAPYAMTGIERDSSGAVSLQQSMTGSLGADNAFSYGVNAGYAGGSGRHAASLAGN
ASYLSPVATLTATAGKGSNYSQVSAGISGGVVAYAGGVGFTPTMGETLAIVEAADAGGARLANGSGLRIDRWGHAVVPGL
VPFSRNQIEIDPKGLPMNVELDSTLQQVAPTAGAVVAVRFATADRGRPAVIRTSTADGKSIPFGAEVQDAHGNNIGTVGQ
GSRIVARGLRAERGQLTVRWGKTAQDSCRLDYVLPAAARRDTRIEVIEAQCH

Specific function: Involved in the export and assembly of the type 3 fimbrial subunit (mrkA) [H]

COG id: COG3188

COG function: function code NU; P pilus assembly protein, porin PapC

Gene ontology:

Cell location: Cell outer membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fimbrial export usher family [H]

Homologues:

Organism=Escherichia coli, GI1786332, Length=838, Percent_Identity=35.799522673031, Blast_Score=484, Evalue=1e-138,
Organism=Escherichia coli, GI1790772, Length=898, Percent_Identity=33.4075723830735, Blast_Score=468, Evalue=1e-132,
Organism=Escherichia coli, GI1789533, Length=842, Percent_Identity=34.5605700712589, Blast_Score=450, Evalue=1e-127,
Organism=Escherichia coli, GI1787172, Length=850, Percent_Identity=33.7647058823529, Blast_Score=417, Evalue=1e-117,
Organism=Escherichia coli, GI1786744, Length=850, Percent_Identity=32.9411764705882, Blast_Score=416, Evalue=1e-117,
Organism=Escherichia coli, GI1788427, Length=759, Percent_Identity=33.7285902503294, Blast_Score=400, Evalue=1e-112,
Organism=Escherichia coli, GI87081778, Length=837, Percent_Identity=27.7180406212664, Blast_Score=249, Evalue=6e-67,
Organism=Escherichia coli, GI1789610, Length=803, Percent_Identity=26.1519302615193, Blast_Score=176, Evalue=5e-45,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000015
- InterPro:   IPR018030 [H]

Pfam domain/function: PF00577 Usher [H]

EC number: NA

Molecular weight: Translated: 90108; Mature: 90108

Theoretical pI: Translated: 9.17; Mature: 9.17

Prosite motif: PS01151 FIMBRIAL_USHER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQKRTAHAIPPSLRPLSAVVMMLVSAGALGANPDPRPAPSSAEVEFNDLFLHQPGGSAVD
CCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEEEEEEECCCCCEEE
FSRFNTGNVVLPGNYRAELYVNQAWLGRMEVRMGETAGKDSPVLPCFDEPLLVRIGADAN
EEECCCCCEEECCCCEEEEEEEHHHCCEEEEEECCCCCCCCCCCCCCCCCEEEEECCCCC
KLTPEATASVQDRDACVPLHAIIAGATASFDSSEQRLDVSVPQAALTRQARGYVDPRYWS
CCCCCHHCCCCCCCCCCCHHHHHCCCCCCCCCCCCEEEEECCHHHHHHHHCCCCCCCCCC
DGVTAATLQYNGSVYQSRAEARTATQGYLGLNAGFNAGPWRFRHKGSLGVDQGNARYQSI
CCCEEEEEEECCCHHHHHHHHHHHCCCEEEECCCCCCCCEEEEECCCCCCCCCCHHHHHH
QTSLQRSVVALRSQLVLGDAFTDGTVFDSVGFRGVQLASDDRMQPESQRGYAPSVRGIAN
HHHHHHHHHHHHHHEEEECCCCCCEEECCCCCCEEEECCCCCCCCHHHCCCCCCCCCCCC
SNARVQVRQNGNLIYETTVAAGPFEIDDLYPTGYGGDLEVVVTEADGSVHVSRVPYAAAV
CCCEEEEEECCCEEEEEEECCCCEECCCCCCCCCCCCEEEEEEECCCCEEEECCCHHHHH
NALRPGVTRYGITAGQYRNAGLHDRPAMLQATVQHGFTNMVTGYGGVVVAEGYLAAAAGA
HHHCCCCHHCCCCCCCCCCCCCCCCCHHHHHHHHHCCHHHHCCCCCEEEECCHHHHHHHH
ALNTVYGAFGADLTHAGTRLTTQPDRHGFSMRISYSKLVEPTGTNVSVAAYRYSSSGYLS
HHHHHHHHCCCCHHCCCCEECCCCCCCCEEEEEEHHHHCCCCCCCEEEEEEEECCCCCEE
FADAMTLRELEHGAMQSTMRGIPRSQLQLTLNQRLQPGYGSLYLSGSVHGYWNRRGTDTQ
HHHHHHHHHHHHHHHHHHHHCCCHHHEEEEEHHCCCCCCCEEEEECCEEEEECCCCCCCE
FQLGYNNSYKSLNYGVAASRQFSVSSGRWESRVMLNIGIPLGKARHAPYAMTGIERDSSG
EEECCCCCCCCEECCEECCEEEECCCCCCCEEEEEEECCCCCCCCCCCEEEECCCCCCCC
AVSLQQSMTGSLGADNAFSYGVNAGYAGGSGRHAASLAGNASYLSPVATLTATAGKGSNY
CEEEHHHCCCCCCCCCCEECCCCCCCCCCCCCEEEEECCCCHHHCCHHEEEEECCCCCCC
SQVSAGISGGVVAYAGGVGFTPTMGETLAIVEAADAGGARLANGSGLRIDRWGHAVVPGL
HHHHCCCCCCEEEEECCCCCCCCCCCEEEEEEECCCCCCEECCCCCEEEECCCCEECCCC
VPFSRNQIEIDPKGLPMNVELDSTLQQVAPTAGAVVAVRFATADRGRPAVIRTSTADGKS
CCCCCCEEEECCCCCEEEEEHHHHHHHHCCCCCEEEEEEEEECCCCCCEEEEECCCCCCC
IPFGAEVQDAHGNNIGTVGQGSRIVARGLRAERGQLTVRWGKTAQDSCRLDYVLPAAARR
CCCCCEEECCCCCCCCCCCCCCHHHHHCCCCCCCEEEEEECCCCCCCCCEEEEECCCCCC
DTRIEVIEAQCH
CCEEEEEEECCC
>Mature Secondary Structure
MQKRTAHAIPPSLRPLSAVVMMLVSAGALGANPDPRPAPSSAEVEFNDLFLHQPGGSAVD
CCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEEEEEEECCCCCEEE
FSRFNTGNVVLPGNYRAELYVNQAWLGRMEVRMGETAGKDSPVLPCFDEPLLVRIGADAN
EEECCCCCEEECCCCEEEEEEEHHHCCEEEEEECCCCCCCCCCCCCCCCCEEEEECCCCC
KLTPEATASVQDRDACVPLHAIIAGATASFDSSEQRLDVSVPQAALTRQARGYVDPRYWS
CCCCCHHCCCCCCCCCCCHHHHHCCCCCCCCCCCCEEEEECCHHHHHHHHCCCCCCCCCC
DGVTAATLQYNGSVYQSRAEARTATQGYLGLNAGFNAGPWRFRHKGSLGVDQGNARYQSI
CCCEEEEEEECCCHHHHHHHHHHHCCCEEEECCCCCCCCEEEEECCCCCCCCCCHHHHHH
QTSLQRSVVALRSQLVLGDAFTDGTVFDSVGFRGVQLASDDRMQPESQRGYAPSVRGIAN
HHHHHHHHHHHHHHEEEECCCCCCEEECCCCCCEEEECCCCCCCCHHHCCCCCCCCCCCC
SNARVQVRQNGNLIYETTVAAGPFEIDDLYPTGYGGDLEVVVTEADGSVHVSRVPYAAAV
CCCEEEEEECCCEEEEEEECCCCEECCCCCCCCCCCCEEEEEEECCCCEEEECCCHHHHH
NALRPGVTRYGITAGQYRNAGLHDRPAMLQATVQHGFTNMVTGYGGVVVAEGYLAAAAGA
HHHCCCCHHCCCCCCCCCCCCCCCCCHHHHHHHHHCCHHHHCCCCCEEEECCHHHHHHHH
ALNTVYGAFGADLTHAGTRLTTQPDRHGFSMRISYSKLVEPTGTNVSVAAYRYSSSGYLS
HHHHHHHHCCCCHHCCCCEECCCCCCCCEEEEEEHHHHCCCCCCCEEEEEEEECCCCCEE
FADAMTLRELEHGAMQSTMRGIPRSQLQLTLNQRLQPGYGSLYLSGSVHGYWNRRGTDTQ
HHHHHHHHHHHHHHHHHHHHCCCHHHEEEEEHHCCCCCCCEEEEECCEEEEECCCCCCCE
FQLGYNNSYKSLNYGVAASRQFSVSSGRWESRVMLNIGIPLGKARHAPYAMTGIERDSSG
EEECCCCCCCCEECCEECCEEEECCCCCCCEEEEEEECCCCCCCCCCCEEEECCCCCCCC
AVSLQQSMTGSLGADNAFSYGVNAGYAGGSGRHAASLAGNASYLSPVATLTATAGKGSNY
CEEEHHHCCCCCCCCCCEECCCCCCCCCCCCCEEEEECCCCHHHCCHHEEEEECCCCCCC
SQVSAGISGGVVAYAGGVGFTPTMGETLAIVEAADAGGARLANGSGLRIDRWGHAVVPGL
HHHHCCCCCCEEEEECCCCCCCCCCCEEEEEEECCCCCCEECCCCCEEEECCCCEECCCC
VPFSRNQIEIDPKGLPMNVELDSTLQQVAPTAGAVVAVRFATADRGRPAVIRTSTADGKS
CCCCCCEEEECCCCCEEEEEHHHHHHHHCCCCCEEEEEEEEECCCCCCEEEEECCCCCCC
IPFGAEVQDAHGNNIGTVGQGSRIVARGLRAERGQLTVRWGKTAQDSCRLDYVLPAAARR
CCCCCEEECCCCCCCCCCCCCCHHHHHCCCCCCCEEEEEECCCCCCCCCEEEEECCCCCC
DTRIEVIEAQCH
CCEEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1670938 [H]