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The map label for this gene is thiL [H]

Identifier: 66047684

GI number: 66047684

Start: 5320863

End: 5321828

Strand: Reverse

Name: thiL [H]

Synonym: Psyr_4457

Alternate gene names: 66047684

Gene position: 5321828-5320863 (Counterclockwise)

Preceding gene: 66047685

Following gene: 66047683

Centisome position: 87.33

GC content: 66.56

Gene sequence:

>966_bases
ATGGGAGAGTTCGAGCTGATCCGCAATTACTTCGCCGCCGCGCCCTGTGCGCAGGCGGGCGAGGAAGTTGCCCTGGGGAT
CGGCGATGACTGCGCGCTGCTGGCGTTGACGCCCGGCGAGCAGTTGGCGATCTCGACCGACACCCTGGTTGCCGGGGTGC
ATTTTCCTGATGTCTGCGACCCCTTTCTGCTTGGCCAGCGTGCGCTGGCAGTGTCTGCCAGTGACCTGGCGGCCATGGGC
GCCAGGCCTGTCGCGTTCACCCTTGCCCTGACCCTGCCGCAGGTCGATGCCGACTGGCTGCAGACCTTCGCTCGCGGCCT
GAACCAGATGGCGCAAGGCTGTTCGCTGCGTCTGATCGGTGGTGATACCACGCGCGGTCCCTTGAGCCTGACCCTGACAG
TGTTTGGCGCTGTGCCGGCCGGATCAGCCCTGACCCGCGCGGGTGCCGAGGCGGGTGACCTGCTGTGTGTCGGCGGCACG
CTGGGTGATGGCGCCGGTGCATTGCCGCTGGTATTGAAGCAGCGCAGCGCCGAACCCTCGATCGCCGAAGCATTGCTGGC
CCGCTACTGGTCGCCCCAACCGCAACTGGCGCTGGGCCAGGCCTTGCGCGGCAGGGCGACGTCGGCGCTGGACATCTCCG
ATGGGCTGCTGGCCGACTGCGGACATATCGCTCGCGCGTCGGGTGTGCGTCTGGTGGTCGAGCGCGACCGGCTGCCGATG
TCCGACCCATTGCTGACCTTGTTCGATCTGCCCTCTGCCCGACAGGCCGCGCTGAGCGGTGGTGATGATTACATCCTGGC
CTTCACCCTGCCCTCCGAACATCTGCCGGTTCTGCTGAAAGAAGGCTGGCCGGTGCATGTCATTGGCCGGGTAGAGCAGG
GGCAAGGCGTCGTGCTTGTCGACGACACGGGGCAAGACGTCACACCCGACACGCGTGGCTACCAGCATTTTGGCGGTGAG
CAGTGA

Upstream 100 bases:

>100_bases
GACGGCCACAAGTTCGTCAATGGCGTGCTGGACAAGCTGGCGCCGCGCCTGCGTGAAGTCGAAGTGAAGGCCCACAAGCG
CTGATTCGCGCCTGACCTTC

Downstream 100 bases:

>100_bases
GCGGATGAGCGCTTCTATCTATCGAACTTTATGATCTAAATGCCCGAGAATTCACCCTGAGCGTCTGCAGGAACCTGCTG
TTACAATGCAAATCTTGCGA

Product: thiamine monophosphate kinase

Products: NA

Alternate protein names: Thiamine-phosphate kinase [H]

Number of amino acids: Translated: 321; Mature: 320

Protein sequence:

>321_residues
MGEFELIRNYFAAAPCAQAGEEVALGIGDDCALLALTPGEQLAISTDTLVAGVHFPDVCDPFLLGQRALAVSASDLAAMG
ARPVAFTLALTLPQVDADWLQTFARGLNQMAQGCSLRLIGGDTTRGPLSLTLTVFGAVPAGSALTRAGAEAGDLLCVGGT
LGDGAGALPLVLKQRSAEPSIAEALLARYWSPQPQLALGQALRGRATSALDISDGLLADCGHIARASGVRLVVERDRLPM
SDPLLTLFDLPSARQAALSGGDDYILAFTLPSEHLPVLLKEGWPVHVIGRVEQGQGVVLVDDTGQDVTPDTRGYQHFGGE
Q

Sequences:

>Translated_321_residues
MGEFELIRNYFAAAPCAQAGEEVALGIGDDCALLALTPGEQLAISTDTLVAGVHFPDVCDPFLLGQRALAVSASDLAAMG
ARPVAFTLALTLPQVDADWLQTFARGLNQMAQGCSLRLIGGDTTRGPLSLTLTVFGAVPAGSALTRAGAEAGDLLCVGGT
LGDGAGALPLVLKQRSAEPSIAEALLARYWSPQPQLALGQALRGRATSALDISDGLLADCGHIARASGVRLVVERDRLPM
SDPLLTLFDLPSARQAALSGGDDYILAFTLPSEHLPVLLKEGWPVHVIGRVEQGQGVVLVDDTGQDVTPDTRGYQHFGGE
Q
>Mature_320_residues
GEFELIRNYFAAAPCAQAGEEVALGIGDDCALLALTPGEQLAISTDTLVAGVHFPDVCDPFLLGQRALAVSASDLAAMGA
RPVAFTLALTLPQVDADWLQTFARGLNQMAQGCSLRLIGGDTTRGPLSLTLTVFGAVPAGSALTRAGAEAGDLLCVGGTL
GDGAGALPLVLKQRSAEPSIAEALLARYWSPQPQLALGQALRGRATSALDISDGLLADCGHIARASGVRLVVERDRLPMS
DPLLTLFDLPSARQAALSGGDDYILAFTLPSEHLPVLLKEGWPVHVIGRVEQGQGVVLVDDTGQDVTPDTRGYQHFGGEQ

Specific function: Thiamine biosynthesis. [C]

COG id: COG0611

COG function: function code H; Thiamine monophosphate kinase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the thiamine-monophosphate kinase family [H]

Homologues:

Organism=Escherichia coli, GI1786619, Length=323, Percent_Identity=47.6780185758514, Blast_Score=242, Evalue=2e-65,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000728
- InterPro:   IPR010918
- InterPro:   IPR016188
- InterPro:   IPR006283 [H]

Pfam domain/function: PF00586 AIRS; PF02769 AIRS_C [H]

EC number: =2.7.4.16 [H]

Molecular weight: Translated: 33371; Mature: 33240

Theoretical pI: Translated: 4.34; Mature: 4.34

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGEFELIRNYFAAAPCAQAGEEVALGIGDDCALLALTPGEQLAISTDTLVAGVHFPDVCD
CCHHHHHHHHHHCCCHHHCCCEEEEECCCCEEEEEECCCCCEEEECCEEEEECCCCCCCC
PFLLGQRALAVSASDLAAMGARPVAFTLALTLPQVDADWLQTFARGLNQMAQGCSLRLIG
HHHHCCHHEEECHHHHHHHCCCCEEEEEEEECCCCCHHHHHHHHHHHHHHHCCCEEEEEC
GDTTRGPLSLTLTVFGAVPAGSALTRAGAEAGDLLCVGGTLGDGAGALPLVLKQRSAEPS
CCCCCCCEEEEEEEEECCCCCHHHHHCCCCCCCEEEECCCCCCCCCCCHHHEECCCCCCH
IAEALLARYWSPQPQLALGQALRGRATSALDISDGLLADCGHIARASGVRLVVERDRLPM
HHHHHHHHHCCCCCCHHHHHHHCCCCCCEEECCCCHHHHHHHHHHCCCEEEEEECCCCCC
SDPLLTLFDLPSARQAALSGGDDYILAFTLPSEHLPVLLKEGWPVHVIGRVEQGQGVVLV
CCCCEEEECCCCHHHHHHCCCCCEEEEEECCCCCCCEEECCCCCEEEEEEEECCCCEEEE
DDTGQDVTPDTRGYQHFGGEQ
ECCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
GEFELIRNYFAAAPCAQAGEEVALGIGDDCALLALTPGEQLAISTDTLVAGVHFPDVCD
CHHHHHHHHHHCCCHHHCCCEEEEECCCCEEEEEECCCCCEEEECCEEEEECCCCCCCC
PFLLGQRALAVSASDLAAMGARPVAFTLALTLPQVDADWLQTFARGLNQMAQGCSLRLIG
HHHHCCHHEEECHHHHHHHCCCCEEEEEEEECCCCCHHHHHHHHHHHHHHHCCCEEEEEC
GDTTRGPLSLTLTVFGAVPAGSALTRAGAEAGDLLCVGGTLGDGAGALPLVLKQRSAEPS
CCCCCCCEEEEEEEEECCCCCHHHHHCCCCCCCEEEECCCCCCCCCCCHHHEECCCCCCH
IAEALLARYWSPQPQLALGQALRGRATSALDISDGLLADCGHIARASGVRLVVERDRLPM
HHHHHHHHHCCCCCCHHHHHHHCCCCCCEEECCCCHHHHHHHHHHCCCEEEEEECCCCCC
SDPLLTLFDLPSARQAALSGGDDYILAFTLPSEHLPVLLKEGWPVHVIGRVEQGQGVVLV
CCCCEEEECCCCHHHHHHCCCCCEEEEEECCCCCCCEEECCCCCEEEEEEEECCCCEEEE
DDTGQDVTPDTRGYQHFGGEQ
ECCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11677609 [H]