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The map label for this gene is ftsZ [H]

Identifier: 59712803

GI number: 59712803

Start: 2467642

End: 2468892

Strand: Reverse

Name: ftsZ [H]

Synonym: VF_2196

Alternate gene names: 59712803

Gene position: 2468892-2467642 (Counterclockwise)

Preceding gene: 59712804

Following gene: 59712802

Centisome position: 85.21

GC content: 44.52

Gene sequence:

>1251_bases
ATGTTTGAGCCGATGATGGAAATGTCCGACGACGCAGTAATTAAAGTTGTTGGTGTAGGTGGCGGTGGCGGTAATGCTAT
CGAGCACATGGTACGAGAATCAATTGAAGGCGTTGAGTTCATCAGTGTAAATACTGATGCACAAGCGCTTCGTAAAACGA
GCGTGAACACCGTTATTCAAATTGGTGGCGACATCACTAAAGGATTAGGTGCTGGTGCAAACCCGCAAGTAGGCCGTGAT
GCAGCTCTAGAAGACCGTGAAGCACTGAAAGAAGTGTTAGCGGGCGCTGATATGGTATTTATCGCAGCTGGTATGGGCGG
CGGTACAGGTACTGGTGCAGCTCCTATTATTGCTGAAGTTGCTAAAGAATTAAATATTCTAACAGTTGCTGTGGTTACAA
AACCATTTAGCTTTGAAGGTCGTAAGCGTCTTGCTTTTGCTGAGCAAGGTATCGAAGAGTTATCAAAACATGTTGACTCA
TTAATTACGATTCCAAACGAAAAATTATTAAAAGTTCTTGGCCGTGGTATTACGTTATTAGAAGCATTTGCAAAAGCGAA
TGATGTTCTTCGTAATGCTGTTCAAGGTATCGCAGAACTTATTACTCGTCCTGGTATGATCAACGTCGATTTCGCCGATG
TTCGTACAGTTATGTCTGAAATGGGACATGCAATGATGGGTAGCGGTATCGCAGTAGGCGAAGATCGTGCAGAACAAGCA
GCAGAAGAAGCGATTTCAAGTCCGTTACTTGAAGATATCGATCTTGCTGGTGCTCGTGGTGTTCTTGTTAACATCACTGC
AGGTTTAGATATGCGTCTTGATGAATTTGAAACTGTTGGTAATACAGTGAAAGCATTTGCATCAGATAACGCAACGGTTG
TTATTGGTACTTCTCTTGATCCTGATATGAGTGACGAAATTCGCGTAACGGTTGTTGCTACAGGTATCGGTACTGAAAAA
AAGCCTGAAATCACGTTAGTGACGAATAAAGCAGCGGCTCCTGCTCAATCGGCTCCAGCAGCGCAACCTGCGGTTCAAGC
ACAAGTAAAACCAAAAGTTGAAGCTCCAGTTGAACCTGTGGTTGAAAAAGCGGCACAAAACGTGCAAGTAACTAAACCAG
CAGCACAGCCATCTGCGCCATCTACATCACCAGCGGCTGGTGTTCAGAATGCGGGTGCGGCACAAGCTAAGCCAGATCAG
AAAGAAGATTATTTAGATATCCCAGCGTTTTTACGACGCCAAGCTGACTAA

Upstream 100 bases:

>100_bases
CAAGTAAGAGCCAATCTTTTACTACCGTAATAAAGAAATTTAAAAATTGGATACTAAAAGAGTTTTAACCTGAGCGAACA
GGAAGAAACGGAGAGAACAA

Downstream 100 bases:

>100_bases
TTAATCATCAAACGATTTGGTTTTATGAAAAATTGTGTGCTAGAATGTCAGACCAGTTCTTAGAATTGGTTTGAAATTAA
GCATATTTATAGTTGAGATG

Product: cell division protein FtsZ

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 416; Mature: 416

Protein sequence:

>416_residues
MFEPMMEMSDDAVIKVVGVGGGGGNAIEHMVRESIEGVEFISVNTDAQALRKTSVNTVIQIGGDITKGLGAGANPQVGRD
AALEDREALKEVLAGADMVFIAAGMGGGTGTGAAPIIAEVAKELNILTVAVVTKPFSFEGRKRLAFAEQGIEELSKHVDS
LITIPNEKLLKVLGRGITLLEAFAKANDVLRNAVQGIAELITRPGMINVDFADVRTVMSEMGHAMMGSGIAVGEDRAEQA
AEEAISSPLLEDIDLAGARGVLVNITAGLDMRLDEFETVGNTVKAFASDNATVVIGTSLDPDMSDEIRVTVVATGIGTEK
KPEITLVTNKAAAPAQSAPAAQPAVQAQVKPKVEAPVEPVVEKAAQNVQVTKPAAQPSAPSTSPAAGVQNAGAAQAKPDQ
KEDYLDIPAFLRRQAD

Sequences:

>Translated_416_residues
MFEPMMEMSDDAVIKVVGVGGGGGNAIEHMVRESIEGVEFISVNTDAQALRKTSVNTVIQIGGDITKGLGAGANPQVGRD
AALEDREALKEVLAGADMVFIAAGMGGGTGTGAAPIIAEVAKELNILTVAVVTKPFSFEGRKRLAFAEQGIEELSKHVDS
LITIPNEKLLKVLGRGITLLEAFAKANDVLRNAVQGIAELITRPGMINVDFADVRTVMSEMGHAMMGSGIAVGEDRAEQA
AEEAISSPLLEDIDLAGARGVLVNITAGLDMRLDEFETVGNTVKAFASDNATVVIGTSLDPDMSDEIRVTVVATGIGTEK
KPEITLVTNKAAAPAQSAPAAQPAVQAQVKPKVEAPVEPVVEKAAQNVQVTKPAAQPSAPSTSPAAGVQNAGAAQAKPDQ
KEDYLDIPAFLRRQAD
>Mature_416_residues
MFEPMMEMSDDAVIKVVGVGGGGGNAIEHMVRESIEGVEFISVNTDAQALRKTSVNTVIQIGGDITKGLGAGANPQVGRD
AALEDREALKEVLAGADMVFIAAGMGGGTGTGAAPIIAEVAKELNILTVAVVTKPFSFEGRKRLAFAEQGIEELSKHVDS
LITIPNEKLLKVLGRGITLLEAFAKANDVLRNAVQGIAELITRPGMINVDFADVRTVMSEMGHAMMGSGIAVGEDRAEQA
AEEAISSPLLEDIDLAGARGVLVNITAGLDMRLDEFETVGNTVKAFASDNATVVIGTSLDPDMSDEIRVTVVATGIGTEK
KPEITLVTNKAAAPAQSAPAAQPAVQAQVKPKVEAPVEPVVEKAAQNVQVTKPAAQPSAPSTSPAAGVQNAGAAQAKPDQ
KEDYLDIPAFLRRQAD

Specific function: This protein is essential to the cell-division process. It seems to assemble into a dynamic ring on the inner surface of the cytoplasmic membrane at the place where division will occur, and the formation of the ring is the signal for septation to begin. B

COG id: COG0206

COG function: function code D; Cell division GTPase

Gene ontology:

Cell location: Cytoplasm. Note=Assembles at the inner surface of the cytoplasmic membrane (By similarity) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ftsZ family [H]

Homologues:

Organism=Escherichia coli, GI1786284, Length=416, Percent_Identity=72.1153846153846, Blast_Score=520, Evalue=1e-149,

Paralogues:

None

Copy number: 320 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020805
- InterPro:   IPR000158
- InterPro:   IPR008280
- InterPro:   IPR018316
- InterPro:   IPR003008 [H]

Pfam domain/function: PF00091 Tubulin [H]

EC number: NA

Molecular weight: Translated: 43191; Mature: 43191

Theoretical pI: Translated: 4.40; Mature: 4.40

Prosite motif: PS01134 FTSZ_1 ; PS01135 FTSZ_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFEPMMEMSDDAVIKVVGVGGGGGNAIEHMVRESIEGVEFISVNTDAQALRKTSVNTVIQ
CCCCCHHCCCCCEEEEEEECCCCCHHHHHHHHHHCCCCEEEEECCHHHHHHHHCCHHEEE
IGGDITKGLGAGANPQVGRDAALEDREALKEVLAGADMVFIAAGMGGGTGTGAAPIIAEV
ECCCHHHCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCEEEEEECCCCCCCCCHHHHHHHH
AKELNILTVAVVTKPFSFEGRKRLAFAEQGIEELSKHVDSLITIPNEKLLKVLGRGITLL
HHHCCEEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCHHHH
EAFAKANDVLRNAVQGIAELITRPGMINVDFADVRTVMSEMGHAMMGSGIAVGEDRAEQA
HHHHHHHHHHHHHHHHHHHHHHCCCEEECCHHHHHHHHHHHCHHHHCCCCCCCCHHHHHH
AEEAISSPLLEDIDLAGARGVLVNITAGLDMRLDEFETVGNTVKAFASDNATVVIGTSLD
HHHHHHCCCHHHHHCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHCCCCCEEEEECCCC
PDMSDEIRVTVVATGIGTEKKPEITLVTNKAAAPAQSAPAAQPAVQAQVKPKVEAPVEPV
CCCCCCEEEEEEEECCCCCCCCCEEEEECCCCCCCCCCCCCCCHHHHCCCCCCCCCHHHH
VEKAAQNVQVTKPAAQPSAPSTSPAAGVQNAGAAQAKPDQKEDYLDIPAFLRRQAD
HHHHHCCEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHCCCC
>Mature Secondary Structure
MFEPMMEMSDDAVIKVVGVGGGGGNAIEHMVRESIEGVEFISVNTDAQALRKTSVNTVIQ
CCCCCHHCCCCCEEEEEEECCCCCHHHHHHHHHHCCCCEEEEECCHHHHHHHHCCHHEEE
IGGDITKGLGAGANPQVGRDAALEDREALKEVLAGADMVFIAAGMGGGTGTGAAPIIAEV
ECCCHHHCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCEEEEEECCCCCCCCCHHHHHHHH
AKELNILTVAVVTKPFSFEGRKRLAFAEQGIEELSKHVDSLITIPNEKLLKVLGRGITLL
HHHCCEEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCHHHH
EAFAKANDVLRNAVQGIAELITRPGMINVDFADVRTVMSEMGHAMMGSGIAVGEDRAEQA
HHHHHHHHHHHHHHHHHHHHHHCCCEEECCHHHHHHHHHHHCHHHHCCCCCCCCHHHHHH
AEEAISSPLLEDIDLAGARGVLVNITAGLDMRLDEFETVGNTVKAFASDNATVVIGTSLD
HHHHHHCCCHHHHHCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHCCCCCEEEEECCCC
PDMSDEIRVTVVATGIGTEKKPEITLVTNKAAAPAQSAPAAQPAVQAQVKPKVEAPVEPV
CCCCCCEEEEEEEECCCCCCCCCEEEEECCCCCCCCCCCCCCCHHHHCCCCCCCCCHHHH
VEKAAQNVQVTKPAAQPSAPSTSPAAGVQNAGAAQAKPDQKEDYLDIPAFLRRQAD
HHHHHCCEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11443086 [H]