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The map label for this gene is ftsA [H]

Identifier: 59712804

GI number: 59712804

Start: 2468925

End: 2470187

Strand: Reverse

Name: ftsA [H]

Synonym: VF_2197

Alternate gene names: 59712804

Gene position: 2470187-2468925 (Counterclockwise)

Preceding gene: 172087760

Following gene: 59712803

Centisome position: 85.25

GC content: 39.19

Gene sequence:

>1263_bases
ATGAGTAAAACGCCAGAAGGCAGTATTATTGTTGGTTTAGACATTGGTACAAACAAAGTTTCAGCGTTAGTTGGCGAAGT
TTTACCTGATGGCCAAGTGAGTGTTATCGGCTCTGGTTCATGTCCATCTCGTGGTATGGATAAAGGTGGTGTAAACGACC
TAGAATCGGTTGTAAAATCGGTTCAAAGAGCGATTGATCAAGCTGAATTGATGGCTGAATGTACCATTACATCAGTGTTT
ATCTCTCTTTCTGGCAAACATATTGCTAGCCAAATCGAGAAAGGTATGGGGTCAATTTCTGAAGAAGAAGTGACTCAAGA
TGACATGGATAGCGTTATTCATACTGCAAAATCTGTTAAGATAGGTGATGAACAGCGTACATTGCATGTAATTCCACAAG
AATTCTCTATTGATGTTCAAAAAGGGATCAGAAACCCTATTGGGTTATCAGGAATGAGAATGGAAGTTAGCGTTCATCTT
ATTACCTGCCATAATGATATGGCACGTAATATAGTGAAAGCGGTAGAACGTTGTGGTTTAAAAGTTGAACATATTATTTT
TTCTGGCTTAGCTTCAAGTAATGCAGTTATTACAGAAGATGAGCGTGATTTAGGTGTTTGTGTTGTTGATATCGGTGCTG
GCACAATGGATATCGCAATTTGGACTGACGGTTCATTACGCCATGCTGAAGTATTACCTTATGCCGGAAATGCAGTAACA
AGTGATATAGCTTATGCTTTTGGTACGCCATTTAACGATGCTGAAAAATTAAAAGTAAAATATGGTTGTGCGATAAGTGA
GCATATTAATCGAGATGAAACGGTCAATGTTCCAAGTGTTGGCGGACGTCCATCTCGAAGTTTACAGCGAAGAATGCTAG
CAGAAGTTATCGAACCAAGGTATTCTGAACTGCTTGGTCTTGTAAATCAGCGAATTGTCTCAATTCAAGACCAATTACGC
GCTGAAGGTACAAAACATCATCTTGCTGCTGGTATTGTATTGACTGGTGGTGGGTCACAGATTGAAGGTTTGGTTGACTG
CGCTGAGCGTGTGTTCCAAACTCAAGTTAGAATTGGTCAACCTTTAGAGGTGACAGGCCTAACAGATTACGTAAAAGAAC
CTTATCAAGCAACAGCTGTAGGGCTTTTACATTACGGTAAAGAAAGTCAGCTACATGACGATGAAGATTATGTGCCAAGT
AAGAGCCAATCTTTTACTACCGTAATAAAGAAATTTAAAAATTGGATACTAAAAGAGTTTTAA

Upstream 100 bases:

>100_bases
AGTAAAAAAGATTCGATAGATTATATAGATCTTCGTTATGACACTGGTGCTGCCGTTGGATGGAAATCCGATGATGTAGA
AAATAAAGAAGAGAATTGAC

Downstream 100 bases:

>100_bases
CCTGAGCGAACAGGAAGAAACGGAGAGAACAAATGTTTGAGCCGATGATGGAAATGTCCGACGACGCAGTAATTAAAGTT
GTTGGTGTAGGTGGCGGTGG

Product: cell division protein FtsA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 420; Mature: 419

Protein sequence:

>420_residues
MSKTPEGSIIVGLDIGTNKVSALVGEVLPDGQVSVIGSGSCPSRGMDKGGVNDLESVVKSVQRAIDQAELMAECTITSVF
ISLSGKHIASQIEKGMGSISEEEVTQDDMDSVIHTAKSVKIGDEQRTLHVIPQEFSIDVQKGIRNPIGLSGMRMEVSVHL
ITCHNDMARNIVKAVERCGLKVEHIIFSGLASSNAVITEDERDLGVCVVDIGAGTMDIAIWTDGSLRHAEVLPYAGNAVT
SDIAYAFGTPFNDAEKLKVKYGCAISEHINRDETVNVPSVGGRPSRSLQRRMLAEVIEPRYSELLGLVNQRIVSIQDQLR
AEGTKHHLAAGIVLTGGGSQIEGLVDCAERVFQTQVRIGQPLEVTGLTDYVKEPYQATAVGLLHYGKESQLHDDEDYVPS
KSQSFTTVIKKFKNWILKEF

Sequences:

>Translated_420_residues
MSKTPEGSIIVGLDIGTNKVSALVGEVLPDGQVSVIGSGSCPSRGMDKGGVNDLESVVKSVQRAIDQAELMAECTITSVF
ISLSGKHIASQIEKGMGSISEEEVTQDDMDSVIHTAKSVKIGDEQRTLHVIPQEFSIDVQKGIRNPIGLSGMRMEVSVHL
ITCHNDMARNIVKAVERCGLKVEHIIFSGLASSNAVITEDERDLGVCVVDIGAGTMDIAIWTDGSLRHAEVLPYAGNAVT
SDIAYAFGTPFNDAEKLKVKYGCAISEHINRDETVNVPSVGGRPSRSLQRRMLAEVIEPRYSELLGLVNQRIVSIQDQLR
AEGTKHHLAAGIVLTGGGSQIEGLVDCAERVFQTQVRIGQPLEVTGLTDYVKEPYQATAVGLLHYGKESQLHDDEDYVPS
KSQSFTTVIKKFKNWILKEF
>Mature_419_residues
SKTPEGSIIVGLDIGTNKVSALVGEVLPDGQVSVIGSGSCPSRGMDKGGVNDLESVVKSVQRAIDQAELMAECTITSVFI
SLSGKHIASQIEKGMGSISEEEVTQDDMDSVIHTAKSVKIGDEQRTLHVIPQEFSIDVQKGIRNPIGLSGMRMEVSVHLI
TCHNDMARNIVKAVERCGLKVEHIIFSGLASSNAVITEDERDLGVCVVDIGAGTMDIAIWTDGSLRHAEVLPYAGNAVTS
DIAYAFGTPFNDAEKLKVKYGCAISEHINRDETVNVPSVGGRPSRSLQRRMLAEVIEPRYSELLGLVNQRIVSIQDQLRA
EGTKHHLAAGIVLTGGGSQIEGLVDCAERVFQTQVRIGQPLEVTGLTDYVKEPYQATAVGLLHYGKESQLHDDEDYVPSK
SQSFTTVIKKFKNWILKEF

Specific function: This protein may be involved in anomalous filament growth. May be a component of the septum [H]

COG id: COG0849

COG function: function code D; Actin-like ATPase involved in cell division

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ftsA/mreB family [H]

Homologues:

Organism=Escherichia coli, GI1786282, Length=420, Percent_Identity=68.5714285714286, Blast_Score=614, Evalue=1e-177,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020823
- InterPro:   IPR003494 [H]

Pfam domain/function: PF02491 FtsA [H]

EC number: NA

Molecular weight: Translated: 45484; Mature: 45353

Theoretical pI: Translated: 5.19; Mature: 5.19

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKTPEGSIIVGLDIGTNKVSALVGEVLPDGQVSVIGSGSCPSRGMDKGGVNDLESVVKS
CCCCCCCCEEEEEECCCHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCCHHHHHHHHHH
VQRAIDQAELMAECTITSVFISLSGKHIASQIEKGMGSISEEEVTQDDMDSVIHTAKSVK
HHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCHHHCCHHHHHHHHHHHHCCE
IGDEQRTLHVIPQEFSIDVQKGIRNPIGLSGMRMEVSVHLITCHNDMARNIVKAVERCGL
ECCCCCEEEECCCHHCEEHHHHCCCCCCCCCEEEEEEEEEEEECCHHHHHHHHHHHHCCC
KVEHIIFSGLASSNAVITEDERDLGVCVVDIGAGTMDIAIWTDGSLRHAEVLPYAGNAVT
EEHHHHHHCCCCCCCEEEECCCCCEEEEEEECCCEEEEEEEECCCCCCEEECCCCCCHHH
SDIAYAFGTPFNDAEKLKVKYGCAISEHINRDETVNVPSVGGRPSRSLQRRMLAEVIEPR
HHHHHHCCCCCCCHHHEEEEECCCHHHHCCCCCEECCCCCCCCCCHHHHHHHHHHHHCHH
YSELLGLVNQRIVSIQDQLRAEGTKHHLAAGIVLTGGGSQIEGLVDCAERVFQTQVRIGQ
HHHHHHHHHHHHHHHHHHHHCCCCHHEEEEEEEEECCCCHHHHHHHHHHHHHHHHHHCCC
PLEVTGLTDYVKEPYQATAVGLLHYGKESQLHDDEDYVPSKSQSFTTVIKKFKNWILKEF
CEEECCCHHHHHCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SKTPEGSIIVGLDIGTNKVSALVGEVLPDGQVSVIGSGSCPSRGMDKGGVNDLESVVKS
CCCCCCCEEEEEECCCHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCCHHHHHHHHHH
VQRAIDQAELMAECTITSVFISLSGKHIASQIEKGMGSISEEEVTQDDMDSVIHTAKSVK
HHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCHHHCCHHHHHHHHHHHHCCE
IGDEQRTLHVIPQEFSIDVQKGIRNPIGLSGMRMEVSVHLITCHNDMARNIVKAVERCGL
ECCCCCEEEECCCHHCEEHHHHCCCCCCCCCEEEEEEEEEEEECCHHHHHHHHHHHHCCC
KVEHIIFSGLASSNAVITEDERDLGVCVVDIGAGTMDIAIWTDGSLRHAEVLPYAGNAVT
EEHHHHHHCCCCCCCEEEECCCCCEEEEEEECCCEEEEEEEECCCCCCEEECCCCCCHHH
SDIAYAFGTPFNDAEKLKVKYGCAISEHINRDETVNVPSVGGRPSRSLQRRMLAEVIEPR
HHHHHHCCCCCCCHHHEEEEECCCHHHHCCCCCEECCCCCCCCCCHHHHHHHHHHHHCHH
YSELLGLVNQRIVSIQDQLRAEGTKHHLAAGIVLTGGGSQIEGLVDCAERVFQTQVRIGQ
HHHHHHHHHHHHHHHHHHHHCCCCHHEEEEEEEEECCCCHHHHHHHHHHHHHHHHHHCCC
PLEVTGLTDYVKEPYQATAVGLLHYGKESQLHDDEDYVPSKSQSFTTVIKKFKNWILKEF
CEEECCCHHHHHCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12384590; 12704152 [H]