| Definition | Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 chromosome chromosome I, complete sequence. |
|---|---|
| Accession | NC_005823 |
| Length | 4,277,185 |
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The map label for this gene is thrC
Identifier: 45656382
GI number: 45656382
Start: 560695
End: 562044
Strand: Direct
Name: thrC
Synonym: LIC10484
Alternate gene names: 45656382
Gene position: 560695-562044 (Clockwise)
Preceding gene: 45656381
Following gene: 45656383
Centisome position: 13.11
GC content: 39.78
Gene sequence:
>1350_bases ATGATCTCTACTTTTACTCGATACAAAGCTGAATTTGAATGTATCAACGATTCCTGTAAAACCAGATATGATCTAAACGA AATCATTTATGAATGTAAAAAGTGCGGAAGTCTTCTCCAAGTTTCCCACGATTTAGATGCGTTAAAATCTGTATCCGGAC AGGAATGGAAGGATCTGTTTGATAGTAGATTTCGTTCTGTCAAGTTTCCCAATTCTTCCGGAATTTGGAACAAAAGAGAA TGGGTTCTTCCTCATATCGAGGATAAGAACATTGTAACTTCAGGTGAAGGTCTTACTCATCTTTTTACTTCGGATCGATT GACCGAAAGTCTTGGACTCGGAAGTTTTTATGTGAAACAGTGTGGGATCTCACACACTGGATCTTTTAAAGATTTAGGAA TGACTGTTTTATTATCTCAAGTAAAACAGATGATTTCTTCTGGGGTTCCGATTCGTGCAGTGGCTTGTGCTAGTTCGGGA GATACTTCGGCCGCTTTAGCATCTTACGCCGCAAAGGCGGGAATTCCTGCGATTATATTTTTACCTGCGGGTAAAGTGTC TCAAGCGCAACTGATTCAACCAGTATCTAACGGTGCTAAGGTGATCGCACTTGATACTGACTTTGATGGTTGTATGAAAA TCGTCAAAGAAGTAACTCGAGAAGCTGGAATTTATTTAGCAAACTCGATGAACTCTTTACGGATTGAAGGACAAAAAACG ATTTCAGTGGAAATCACTCAACAGTTAGGGTGGAAGGTTCCGGATTGGATCGTAATTCCGGGTGGAAATTTAGGAAACGT ATCTGCGTTAGGTGCTGGTTTCGAGATGATGTTTTCTTTGGGGCTAATAGATAAACTTCCGAGGATCGTTTTAGCACAAG CGGAACACGCAAATCCTCTTTATCTTTCTTATTTAAAGAATTTTGAAAGTTTTGAACCGGTTTCTGCAAAAACGACTCTT GCTTCTGCGATTCAAATTGGAAATCCGGTTTCGATTCAAAAGGCGATCAAAACTCTTAAAAAGTTCAATGGGGTTGTGGA ACAGGCCAGCGAATCGGAGTTAGCCGATGCGGCCTCTAAAGCGGACTTATTCGGTTTATACAATGATCCTCATACGGGTG TGGCTTTGGCGGCTTTGGAAAAGTTGATTCAAAAAGGAACCATTTCTAAAGGTGAGAGTGTAGTAGTCATTTCGACTGCT CACGGATTGAAATTCACAGAGTTTAAGTTGAAATTCCACGGAGGTGAAATTCCTGGAACGGATTTTAAAATTGTAAATTC AATTCATAAGGTAGAGCCTAAAGCGGATAAAGTAGTCGGTTTAATTCGGGATTTATTAGTTTCAAAATAA
Upstream 100 bases:
>100_bases TGCAAGACTTGCCAAGTTAAAATCTCTTTTGGACGGGGGGTTGATTACTCAAGAAGAATTTGATACCAAAAAAAAGGACA TTTTGAATTCTATCTAAAAT
Downstream 100 bases:
>100_bases TTTGTTTTTGAAAATTGGGATTTAAACCGCGCACTAACCGAAAAATACAAGGTGGAGTTTTTGGTGCAAGGGCCTACTTT AAATTTTCTTATCTTTCTGT
Product: threonine synthase
Products: NA
Alternate protein names: TS [H]
Number of amino acids: Translated: 449; Mature: 449
Protein sequence:
>449_residues MISTFTRYKAEFECINDSCKTRYDLNEIIYECKKCGSLLQVSHDLDALKSVSGQEWKDLFDSRFRSVKFPNSSGIWNKRE WVLPHIEDKNIVTSGEGLTHLFTSDRLTESLGLGSFYVKQCGISHTGSFKDLGMTVLLSQVKQMISSGVPIRAVACASSG DTSAALASYAAKAGIPAIIFLPAGKVSQAQLIQPVSNGAKVIALDTDFDGCMKIVKEVTREAGIYLANSMNSLRIEGQKT ISVEITQQLGWKVPDWIVIPGGNLGNVSALGAGFEMMFSLGLIDKLPRIVLAQAEHANPLYLSYLKNFESFEPVSAKTTL ASAIQIGNPVSIQKAIKTLKKFNGVVEQASESELADAASKADLFGLYNDPHTGVALAALEKLIQKGTISKGESVVVISTA HGLKFTEFKLKFHGGEIPGTDFKIVNSIHKVEPKADKVVGLIRDLLVSK
Sequences:
>Translated_449_residues MISTFTRYKAEFECINDSCKTRYDLNEIIYECKKCGSLLQVSHDLDALKSVSGQEWKDLFDSRFRSVKFPNSSGIWNKRE WVLPHIEDKNIVTSGEGLTHLFTSDRLTESLGLGSFYVKQCGISHTGSFKDLGMTVLLSQVKQMISSGVPIRAVACASSG DTSAALASYAAKAGIPAIIFLPAGKVSQAQLIQPVSNGAKVIALDTDFDGCMKIVKEVTREAGIYLANSMNSLRIEGQKT ISVEITQQLGWKVPDWIVIPGGNLGNVSALGAGFEMMFSLGLIDKLPRIVLAQAEHANPLYLSYLKNFESFEPVSAKTTL ASAIQIGNPVSIQKAIKTLKKFNGVVEQASESELADAASKADLFGLYNDPHTGVALAALEKLIQKGTISKGESVVVISTA HGLKFTEFKLKFHGGEIPGTDFKIVNSIHKVEPKADKVVGLIRDLLVSK >Mature_449_residues MISTFTRYKAEFECINDSCKTRYDLNEIIYECKKCGSLLQVSHDLDALKSVSGQEWKDLFDSRFRSVKFPNSSGIWNKRE WVLPHIEDKNIVTSGEGLTHLFTSDRLTESLGLGSFYVKQCGISHTGSFKDLGMTVLLSQVKQMISSGVPIRAVACASSG DTSAALASYAAKAGIPAIIFLPAGKVSQAQLIQPVSNGAKVIALDTDFDGCMKIVKEVTREAGIYLANSMNSLRIEGQKT ISVEITQQLGWKVPDWIVIPGGNLGNVSALGAGFEMMFSLGLIDKLPRIVLAQAEHANPLYLSYLKNFESFEPVSAKTTL ASAIQIGNPVSIQKAIKTLKKFNGVVEQASESELADAASKADLFGLYNDPHTGVALAALEKLIQKGTISKGESVVVISTA HGLKFTEFKLKFHGGEIPGTDFKIVNSIHKVEPKADKVVGLIRDLLVSK
Specific function: Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine [H]
COG id: COG0498
COG function: function code E; Threonine synthase
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the threonine synthase family [H]
Homologues:
Organism=Escherichia coli, GI1786185, Length=301, Percent_Identity=25.5813953488372, Blast_Score=82, Evalue=5e-17,
Paralogues:
None
Copy number: 560 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR001926 - InterPro: IPR000634 - InterPro: IPR004450 [H]
Pfam domain/function: PF00291 PALP [H]
EC number: =4.2.3.1 [H]
Molecular weight: Translated: 48666; Mature: 48666
Theoretical pI: Translated: 8.27; Mature: 8.27
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
1.6 %Cys (Translated Protein) 1.6 %Met (Translated Protein) 3.1 %Cys+Met (Translated Protein) 1.6 %Cys (Mature Protein) 1.6 %Met (Mature Protein) 3.1 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MISTFTRYKAEFECINDSCKTRYDLNEIIYECKKCGSLLQVSHDLDALKSVSGQEWKDLF CCCCCHHHHHHHHHHCCHHHCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHCCCHHHHHHH DSRFRSVKFPNSSGIWNKREWVLPHIEDKNIVTSGEGLTHLFTSDRLTESLGLGSFYVKQ HHHHHEEECCCCCCCCCCCCEECCCCCCCCEEECCCCCEEEHHHHHHHHHHCCCHHHHHH CGISHTGSFKDLGMTVLLSQVKQMISSGVPIRAVACASSGDTSAALASYAAKAGIPAIIF CCCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCHHHHHHHHHHCCCCEEEE LPAGKVSQAQLIQPVSNGAKVIALDTDFDGCMKIVKEVTREAGIYLANSMNSLRIEGQKT ECCCCCCHHHHHHHHCCCCEEEEEECCHHHHHHHHHHHHHHCCEEEECCCCCEEECCCEE ISVEITQQLGWKVPDWIVIPGGNLGNVSALGAGFEMMFSLGLIDKLPRIVLAQAEHANPL EEEEEHHHCCCCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHCCHHEEHHCCCCCCH YLSYLKNFESFEPVSAKTTLASAIQIGNPVSIQKAIKTLKKFNGVVEQASESELADAASK HHHHHHCCCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH ADLFGLYNDPHTGVALAALEKLIQKGTISKGESVVVISTAHGLKFTEFKLKFHGGEIPGT HHEEECCCCCCCHHHHHHHHHHHHCCCCCCCCEEEEEEECCCCEEEEEEEEEECCCCCCC DFKIVNSIHKVEPKADKVVGLIRDLLVSK CHHHHHHHHHCCCHHHHHHHHHHHHHCCC >Mature Secondary Structure MISTFTRYKAEFECINDSCKTRYDLNEIIYECKKCGSLLQVSHDLDALKSVSGQEWKDLF CCCCCHHHHHHHHHHCCHHHCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHCCCHHHHHHH DSRFRSVKFPNSSGIWNKREWVLPHIEDKNIVTSGEGLTHLFTSDRLTESLGLGSFYVKQ HHHHHEEECCCCCCCCCCCCEECCCCCCCCEEECCCCCEEEHHHHHHHHHHCCCHHHHHH CGISHTGSFKDLGMTVLLSQVKQMISSGVPIRAVACASSGDTSAALASYAAKAGIPAIIF CCCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCHHHHHHHHHHCCCCEEEE LPAGKVSQAQLIQPVSNGAKVIALDTDFDGCMKIVKEVTREAGIYLANSMNSLRIEGQKT ECCCCCCHHHHHHHHCCCCEEEEEECCHHHHHHHHHHHHHHCCEEEECCCCCEEECCCEE ISVEITQQLGWKVPDWIVIPGGNLGNVSALGAGFEMMFSLGLIDKLPRIVLAQAEHANPL EEEEEHHHCCCCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHCCHHEEHHCCCCCCH YLSYLKNFESFEPVSAKTTLASAIQIGNPVSIQKAIKTLKKFNGVVEQASESELADAASK HHHHHHCCCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH ADLFGLYNDPHTGVALAALEKLIQKGTISKGESVVVISTAHGLKFTEFKLKFHGGEIPGT HHEEECCCCCCCHHHHHHHHHHHHCCCCCCCCEEEEEEECCCCEEEEEEEEEECCCCCCC DFKIVNSIHKVEPKADKVVGLIRDLLVSK CHHHHHHHHHCCCHHHHHHHHHHHHHCCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: 8688087 [H]