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The map label for this gene is 38233708

Identifier: 38233708

GI number: 38233708

Start: 1101650

End: 1103803

Strand: Direct

Name: 38233708

Synonym: DIP1118

Alternate gene names: NA

Gene position: 1101650-1103803 (Clockwise)

Preceding gene: 38233706

Following gene: 38233709

Centisome position: 44.27

GC content: 55.8

Gene sequence:

>2154_bases
ATGTTTGAGGTGCTATACGGCAGCCGAAAACGGGCGCTTTTCACCGTTATCGGCTGGATAATCATGATCGGGGTGTTTGC
TGCACTGGCACCAACAATTGATGACGTCCTCACTAAGGGCAACAATAACGCGGGCGCTGATGCTGCATCGACACAGGCTG
CACAACTGATTGAAATGAATTTTCCTGATGCTGACGCAGTTCCCGCGATCCTGACGGTGCGAGGCGGAGACGCTAACGTA
TCCAAAGTGTTGGCGGCAGTCGATTCGGTGAGAGAAAACGTTGACCGCTTTGGGCCGTCGATAAGCGCGGCGTGCAAACG
TCCCAGTCCTACGTGCGTTCCCGCTAGCACAACGGAAATGACCAGCGGTGACACCAATCTAGTGGTCATACCAGTCACAG
GTGATCCCACGACGACCGAATATCGCGACGATATTAAGACGCTACGTGCCGAGCTCGCTCATGCATTTGGGGTAGAAGAC
CTAACTCCCGATGCAGCACCTGTCCATGTGACTGGTCCGGTGGGCATTGTTACTGACACCGTGAACGTGTTCGCTGGTGG
AGACAAGATTCTGTTATTGGCAACGATGCTGCTCGTTTTGGTTATTTTGCTTGCCGTTTACCGTGCACCGCTCATGGCGC
TACTGCCGCTGTTCGCGGTAGGTATGGCCATGCGACTGGCTCAGACTGGTGGTGCACTTCTTGCCGACGCTGGAATCATT
AATATCTCCAGCCAGACCGCATCTATTATGACCGTGCTGCTTTTCGGCGTGGGCACTGACTATGCGCTGATCATTAATGC
CCGCTGGCGCGAACATCTCCGAGACACCAACGATCCAGCGCGTGCAATGATCGTCGCGATGGGGCATGTGCTCCCTGTGC
TGCTGTCTAGTGCCGGCACCATTGTTGCCGCGATGCTCGCTCTGTTAACCACTACTTCTCCCACTCTCCAAGGATTTGGC
CCCTACCTAGCTATTGGTGTCGTATCTGCAATGATCGCGGCACTGACGCTTCTGCCAGCGCTGATGGTGTTAGCTGGACG
TGTTGCGCTGTGGCCAAACAAACCTGAACTTGGCCACGACTCCAAGATCTGGACCAAAGTGGCTGATCTGGTTACCACAA
AGCCCAAGGCCATTTTGGCTGGTACTGCGGCGCTCATGGTTGTTCTAGCGCTCGGTCTGCTCAACTACTCAGTTTCCTAC
AACCTGATGTCAGGCTTCCGCATCGCAACTGATTCAGCCGCTGGCCAGAAGGTAATCGCGCAGGACTTTGGTGAAGGTGA
AATCGCGCCGTCCACCATGATTGTCACTGGCCCAGGCGCAGACGCAGCAGCTAAGGCGATTGCTGAACAACTCCCGCAAC
AGCTTCCAGGGGACGTCACGCGCGCAGCCTTTTCGCCTCGGAAGGACGTGACCGAAGACGGCTCGGCTGCCCGTGTCGAC
GTAGTGCTCAACGCTGATCCATACTCCACGACGGCCTTTGACATGTTGGACCGCGCTACGGAACAAGCAGGTGAGATCGC
AGGTTCCGAAGTGAGAGTTGCCAGCGCTGGTGAAACCGCCACTGCCCGAGATAGTGCTGCCGAGGTCACTCACGACTTCA
CACTCCTTGTGCCACTGATCTTCCTTGTGATCGCTTTGATCCTCGGACTGTTGCTGCGGTCGTGGCTGGCTCCGATCTAT
CTCATCGCCACACTTGGCCTATCGTTTGCAGCAACGCTCGGCCTCGTTGCCTTTATCACCCTCACGGTGCAAGGCGATAC
CGGTTTTGGCAGCTACGTGCCGGTGTATGTGCTGGTGTTCCTCACAGCGCTTGGTGTCGACTACACCATCTTTGTGATGG
CACGATTGCGTGAAGAAATGCGAGATAAAACCATGGCGGAAGCCATGCGCCGCGCAATTATTGCCACCGGTGGCGTGGTG
TCTTCTGCAGGACTTATTTTGGCCGCAACATTTGCCGTGCTGATGACGCAGCCCATCCGCGAGCTCTACCAATTCGGTAT
GGCCATGATGCTCGGCATTTTGATCGACACTTTTATCATCCGACCGCTCATGGTACCGGCAATCGTTACCCTCCTAGGTG
ATCGCGCGCTGCTGCCAGCGAAGCCAAGGCAGGAGAGCTGCGAGGCTTCTATAGAGCCTGTGCCTGCCTCATAA

Upstream 100 bases:

>100_bases
CGGCCGGGGTTATCTGGTTGCAAGAATGTGACAGGGTGTCACATAATAGGCACGACTGTGACACCTTGTCACGGCTGGGT
TGACTATGAGGAAGACAAAC

Downstream 100 bases:

>100_bases
TCAATCTGTAACGCCCGAAGGGGCGACACCTGTGTCCATGCCGGTCATAGGCGCCGCCCTTTCACATTATCCATCGGGGG
TAATTGGGTAGGCATGATTA

Product: MmpL family integral membrane protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 717; Mature: 717

Protein sequence:

>717_residues
MFEVLYGSRKRALFTVIGWIIMIGVFAALAPTIDDVLTKGNNNAGADAASTQAAQLIEMNFPDADAVPAILTVRGGDANV
SKVLAAVDSVRENVDRFGPSISAACKRPSPTCVPASTTEMTSGDTNLVVIPVTGDPTTTEYRDDIKTLRAELAHAFGVED
LTPDAAPVHVTGPVGIVTDTVNVFAGGDKILLLATMLLVLVILLAVYRAPLMALLPLFAVGMAMRLAQTGGALLADAGII
NISSQTASIMTVLLFGVGTDYALIINARWREHLRDTNDPARAMIVAMGHVLPVLLSSAGTIVAAMLALLTTTSPTLQGFG
PYLAIGVVSAMIAALTLLPALMVLAGRVALWPNKPELGHDSKIWTKVADLVTTKPKAILAGTAALMVVLALGLLNYSVSY
NLMSGFRIATDSAAGQKVIAQDFGEGEIAPSTMIVTGPGADAAAKAIAEQLPQQLPGDVTRAAFSPRKDVTEDGSAARVD
VVLNADPYSTTAFDMLDRATEQAGEIAGSEVRVASAGETATARDSAAEVTHDFTLLVPLIFLVIALILGLLLRSWLAPIY
LIATLGLSFAATLGLVAFITLTVQGDTGFGSYVPVYVLVFLTALGVDYTIFVMARLREEMRDKTMAEAMRRAIIATGGVV
SSAGLILAATFAVLMTQPIRELYQFGMAMMLGILIDTFIIRPLMVPAIVTLLGDRALLPAKPRQESCEASIEPVPAS

Sequences:

>Translated_717_residues
MFEVLYGSRKRALFTVIGWIIMIGVFAALAPTIDDVLTKGNNNAGADAASTQAAQLIEMNFPDADAVPAILTVRGGDANV
SKVLAAVDSVRENVDRFGPSISAACKRPSPTCVPASTTEMTSGDTNLVVIPVTGDPTTTEYRDDIKTLRAELAHAFGVED
LTPDAAPVHVTGPVGIVTDTVNVFAGGDKILLLATMLLVLVILLAVYRAPLMALLPLFAVGMAMRLAQTGGALLADAGII
NISSQTASIMTVLLFGVGTDYALIINARWREHLRDTNDPARAMIVAMGHVLPVLLSSAGTIVAAMLALLTTTSPTLQGFG
PYLAIGVVSAMIAALTLLPALMVLAGRVALWPNKPELGHDSKIWTKVADLVTTKPKAILAGTAALMVVLALGLLNYSVSY
NLMSGFRIATDSAAGQKVIAQDFGEGEIAPSTMIVTGPGADAAAKAIAEQLPQQLPGDVTRAAFSPRKDVTEDGSAARVD
VVLNADPYSTTAFDMLDRATEQAGEIAGSEVRVASAGETATARDSAAEVTHDFTLLVPLIFLVIALILGLLLRSWLAPIY
LIATLGLSFAATLGLVAFITLTVQGDTGFGSYVPVYVLVFLTALGVDYTIFVMARLREEMRDKTMAEAMRRAIIATGGVV
SSAGLILAATFAVLMTQPIRELYQFGMAMMLGILIDTFIIRPLMVPAIVTLLGDRALLPAKPRQESCEASIEPVPAS
>Mature_717_residues
MFEVLYGSRKRALFTVIGWIIMIGVFAALAPTIDDVLTKGNNNAGADAASTQAAQLIEMNFPDADAVPAILTVRGGDANV
SKVLAAVDSVRENVDRFGPSISAACKRPSPTCVPASTTEMTSGDTNLVVIPVTGDPTTTEYRDDIKTLRAELAHAFGVED
LTPDAAPVHVTGPVGIVTDTVNVFAGGDKILLLATMLLVLVILLAVYRAPLMALLPLFAVGMAMRLAQTGGALLADAGII
NISSQTASIMTVLLFGVGTDYALIINARWREHLRDTNDPARAMIVAMGHVLPVLLSSAGTIVAAMLALLTTTSPTLQGFG
PYLAIGVVSAMIAALTLLPALMVLAGRVALWPNKPELGHDSKIWTKVADLVTTKPKAILAGTAALMVVLALGLLNYSVSY
NLMSGFRIATDSAAGQKVIAQDFGEGEIAPSTMIVTGPGADAAAKAIAEQLPQQLPGDVTRAAFSPRKDVTEDGSAARVD
VVLNADPYSTTAFDMLDRATEQAGEIAGSEVRVASAGETATARDSAAEVTHDFTLLVPLIFLVIALILGLLLRSWLAPIY
LIATLGLSFAATLGLVAFITLTVQGDTGFGSYVPVYVLVFLTALGVDYTIFVMARLREEMRDKTMAEAMRRAIIATGGVV
SSAGLILAATFAVLMTQPIRELYQFGMAMMLGILIDTFIIRPLMVPAIVTLLGDRALLPAKPRQESCEASIEPVPAS

Specific function: Unknown

COG id: COG2409

COG function: function code R; Predicted drug exporters of the RND superfamily

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mmpL family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004869
- InterPro:   IPR000731 [H]

Pfam domain/function: PF03176 MMPL [H]

EC number: NA

Molecular weight: Translated: 75215; Mature: 75215

Theoretical pI: Translated: 4.72; Mature: 4.72

Prosite motif: PS50156 SSD

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFEVLYGSRKRALFTVIGWIIMIGVFAALAPTIDDVLTKGNNNAGADAASTQAAQLIEMN
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCC
FPDADAVPAILTVRGGDANVSKVLAAVDSVRENVDRFGPSISAACKRPSPTCVPASTTEM
CCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCCCCCCCCCCCCC
TSGDTNLVVIPVTGDPTTTEYRDDIKTLRAELAHAFGVEDLTPDAAPVHVTGPVGIVTDT
CCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEECCCEEEECC
VNVFAGGDKILLLATMLLVLVILLAVYRAPLMALLPLFAVGMAMRLAQTGGALLADAGII
HHEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCEE
NISSQTASIMTVLLFGVGTDYALIINARWREHLRDTNDPARAMIVAMGHVLPVLLSSAGT
EECCHHHHHHHHHHHHCCCCEEEEEEHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCHH
IVAAMLALLTTTSPTLQGFGPYLAIGVVSAMIAALTLLPALMVLAGRVALWPNKPELGHD
HHHHHHHHHHCCCCCHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCEEECCCCCCCCCC
SKIWTKVADLVTTKPKAILAGTAALMVVLALGLLNYSVSYNLMSGFRIATDSAAGQKVIA
HHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHEEHHHCCCEEECCCCCCCHHHH
QDFGEGEIAPSTMIVTGPGADAAAKAIAEQLPQQLPGDVTRAAFSPRKDVTEDGSAARVD
HHCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHCCCHHHHHHCCCCCCCCCCCCCEEEE
VVLNADPYSTTAFDMLDRATEQAGEIAGSEVRVASAGETATARDSAAEVTHDFTLLVPLI
EEEECCCCCHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCCHHHHHHHHHHHHHHHH
FLVIALILGLLLRSWLAPIYLIATLGLSFAATLGLVAFITLTVQGDTGFGSYVPVYVLVF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCCCHHHHHHHHH
LTALGVDYTIFVMARLREEMRDKTMAEAMRRAIIATGGVVSSAGLILAATFAVLMTQPIR
HHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHH
ELYQFGMAMMLGILIDTFIIRPLMVPAIVTLLGDRALLPAKPRQESCEASIEPVPAS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHCCCCCCCCCCC
>Mature Secondary Structure
MFEVLYGSRKRALFTVIGWIIMIGVFAALAPTIDDVLTKGNNNAGADAASTQAAQLIEMN
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCC
FPDADAVPAILTVRGGDANVSKVLAAVDSVRENVDRFGPSISAACKRPSPTCVPASTTEM
CCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCCCCCCCCCCCCC
TSGDTNLVVIPVTGDPTTTEYRDDIKTLRAELAHAFGVEDLTPDAAPVHVTGPVGIVTDT
CCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEECCCEEEECC
VNVFAGGDKILLLATMLLVLVILLAVYRAPLMALLPLFAVGMAMRLAQTGGALLADAGII
HHEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCEE
NISSQTASIMTVLLFGVGTDYALIINARWREHLRDTNDPARAMIVAMGHVLPVLLSSAGT
EECCHHHHHHHHHHHHCCCCEEEEEEHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCHH
IVAAMLALLTTTSPTLQGFGPYLAIGVVSAMIAALTLLPALMVLAGRVALWPNKPELGHD
HHHHHHHHHHCCCCCHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCEEECCCCCCCCCC
SKIWTKVADLVTTKPKAILAGTAALMVVLALGLLNYSVSYNLMSGFRIATDSAAGQKVIA
HHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHEEHHHCCCEEECCCCCCCHHHH
QDFGEGEIAPSTMIVTGPGADAAAKAIAEQLPQQLPGDVTRAAFSPRKDVTEDGSAARVD
HHCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHCCCHHHHHHCCCCCCCCCCCCCEEEE
VVLNADPYSTTAFDMLDRATEQAGEIAGSEVRVASAGETATARDSAAEVTHDFTLLVPLI
EEEECCCCCHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCCHHHHHHHHHHHHHHHH
FLVIALILGLLLRSWLAPIYLIATLGLSFAATLGLVAFITLTVQGDTGFGSYVPVYVLVF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCCCHHHHHHHHH
LTALGVDYTIFVMARLREEMRDKTMAEAMRRAIIATGGVVSSAGLILAATFAVLMTQPIR
HHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHH
ELYQFGMAMMLGILIDTFIIRPLMVPAIVTLLGDRALLPAKPRQESCEASIEPVPAS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12000953 [H]