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The map label for this gene is yitJ [H]

Identifier: 37520358

GI number: 37520358

Start: 840819

End: 841712

Strand: Direct

Name: yitJ [H]

Synonym: glr0789

Alternate gene names: 37520358

Gene position: 840819-841712 (Clockwise)

Preceding gene: 37520355

Following gene: 37520359

Centisome position: 18.05

GC content: 64.88

Gene sequence:

>894_bases
ATGGTGAAGTCAGCCCGCCTCGAGACGGCCGCCGAGCGCAAGGAATTTTTGATCACCGCCGAGGTGATGCCTCCCAAAGG
GCCGGACATAGAAGCCTTTCTAGAAAAAGCCACTCTGCTCAAAAACCGGGTGCATGCCGTCAATGTCACCGATTCCAACC
GGGCGGTGATGCGCATGAGCCCGCTTGCCGCCTCGGCATTGCTGGTGCAGCGGGGGATCGAGCCTATCTGCCAGCTGGCC
TGCCGCGACCGCAACCGCATCGCTCTGCAGGGCGATCTGCTCGGGGCGGAGGCGCTGGGTATCCACAATATCCTGGCGCT
CACCGGCGATCCGGTCGGTTGCGGCGATCACCCCCAGGCACGGGCGGTCTGCGACCTCGAATCGGTGCGGCTGCTCAGGG
TGATCGGCGGGCTCAACCGGGGCTTCGACAGCGCCGGCAACGCCCTGAGCAGCCCCACGCGCCTGTTTGCCGGGGCGGCC
ATCGATCCGCAGTGCACCAGCGAAGCGGGGCTGCGCTCCCGCTTTCGGCGCAAGGTGGAGTCGGGGGCGCGCTTTTTTCA
AAGCCAGCTGGTCACCGATTTTGAGCGTCTGGCCTGGTTCATGGACGCAATTGCCCACGAGAGCGCCCGGCCGGTGCTCG
CCGGGATATTCTTGCTCAAATCCGCCAAGAATGCCGAATTCATCAACCGCAATCTGCCCGGGGTCACCATTCCGGAGGGG
ATCATCCGGCGGCTCGCCGGGGCGTGCGATCCCCTCAAAGAAGGCACGGCGATCGCCGCCGAGCAGGTGGCCAAGGCCCG
GCAGATCTGCGACGGCGTCCATCTGATGGCCATCCGCAAGGAGGAGTTGATTCCCGAAATTCTCGACCTGGCCGGTATCG
CGCCTGTGCAATAG

Upstream 100 bases:

>100_bases
AAAATCGCCGGCTCCTGCGGTGGCCGGTCGGTCTGGGACGGCTCGGCGGGTCGCCCGAATATAGGTACCATGCATAGATA
CCCAGGACAACCCTCGACCC

Downstream 100 bases:

>100_bases
ACAATTTGCCGCCGGGTGGGGCATCCGGGCGTGGTAGGATGACCCCAACTTTTGACGGGGTGTTCATGGCAGGTCTCCTG
CGGCGGCTGGGTGCGGCGGC

Product: hypothetical protein

Products: NA

Alternate protein names: Homocysteine S-methyltransferase; S-methylmethionine:homocysteine methyltransferase; 5,10-methylenetetrahydrofolate reductase [H]

Number of amino acids: Translated: 297; Mature: 297

Protein sequence:

>297_residues
MVKSARLETAAERKEFLITAEVMPPKGPDIEAFLEKATLLKNRVHAVNVTDSNRAVMRMSPLAASALLVQRGIEPICQLA
CRDRNRIALQGDLLGAEALGIHNILALTGDPVGCGDHPQARAVCDLESVRLLRVIGGLNRGFDSAGNALSSPTRLFAGAA
IDPQCTSEAGLRSRFRRKVESGARFFQSQLVTDFERLAWFMDAIAHESARPVLAGIFLLKSAKNAEFINRNLPGVTIPEG
IIRRLAGACDPLKEGTAIAAEQVAKARQICDGVHLMAIRKEELIPEILDLAGIAPVQ

Sequences:

>Translated_297_residues
MVKSARLETAAERKEFLITAEVMPPKGPDIEAFLEKATLLKNRVHAVNVTDSNRAVMRMSPLAASALLVQRGIEPICQLA
CRDRNRIALQGDLLGAEALGIHNILALTGDPVGCGDHPQARAVCDLESVRLLRVIGGLNRGFDSAGNALSSPTRLFAGAA
IDPQCTSEAGLRSRFRRKVESGARFFQSQLVTDFERLAWFMDAIAHESARPVLAGIFLLKSAKNAEFINRNLPGVTIPEG
IIRRLAGACDPLKEGTAIAAEQVAKARQICDGVHLMAIRKEELIPEILDLAGIAPVQ
>Mature_297_residues
MVKSARLETAAERKEFLITAEVMPPKGPDIEAFLEKATLLKNRVHAVNVTDSNRAVMRMSPLAASALLVQRGIEPICQLA
CRDRNRIALQGDLLGAEALGIHNILALTGDPVGCGDHPQARAVCDLESVRLLRVIGGLNRGFDSAGNALSSPTRLFAGAA
IDPQCTSEAGLRSRFRRKVESGARFFQSQLVTDFERLAWFMDAIAHESARPVLAGIFLLKSAKNAEFINRNLPGVTIPEG
IIRRLAGACDPLKEGTAIAAEQVAKARQICDGVHLMAIRKEELIPEILDLAGIAPVQ

Specific function: Unknown

COG id: COG0685

COG function: function code E; 5,10-methylenetetrahydrofolate reductase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 Hcy-binding domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003171
- InterPro:   IPR003726 [H]

Pfam domain/function: PF02219 MTHFR; PF02574 S-methyl_trans [H]

EC number: =2.1.1.10; =1.5.1.20 [H]

Molecular weight: Translated: 32041; Mature: 32041

Theoretical pI: Translated: 8.30; Mature: 8.30

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVKSARLETAAERKEFLITAEVMPPKGPDIEAFLEKATLLKNRVHAVNVTDSNRAVMRMS
CCCCHHHHHHHHHHHEEEEEEECCCCCCCHHHHHHHHHHHHCCCEEEEECCCCCEEEEEC
PLAASALLVQRGIEPICQLACRDRNRIALQGDLLGAEALGIHNILALTGDPVGCGDHPQA
HHHHHHHHHHHCHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHEEECCCCCCCCCCCCH
RAVCDLESVRLLRVIGGLNRGFDSAGNALSSPTRLFAGAAIDPQCTSEAGLRSRFRRKVE
HHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHCCCCCCCCCCHHHHHHHHHHHHHH
SGARFFQSQLVTDFERLAWFMDAIAHESARPVLAGIFLLKSAKNAEFINRNLPGVTIPEG
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCHHHHHCCCCCCCCCHH
IIRRLAGACDPLKEGTAIAAEQVAKARQICDGVHLMAIRKEELIPEILDLAGIAPVQ
HHHHHHHCCCCHHCCHHHHHHHHHHHHHHHCCHHHEEHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MVKSARLETAAERKEFLITAEVMPPKGPDIEAFLEKATLLKNRVHAVNVTDSNRAVMRMS
CCCCHHHHHHHHHHHEEEEEEECCCCCCCHHHHHHHHHHHHCCCEEEEECCCCCEEEEEC
PLAASALLVQRGIEPICQLACRDRNRIALQGDLLGAEALGIHNILALTGDPVGCGDHPQA
HHHHHHHHHHHCHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHEEECCCCCCCCCCCCH
RAVCDLESVRLLRVIGGLNRGFDSAGNALSSPTRLFAGAAIDPQCTSEAGLRSRFRRKVE
HHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHCCCCCCCCCCHHHHHHHHHHHHHH
SGARFFQSQLVTDFERLAWFMDAIAHESARPVLAGIFLLKSAKNAEFINRNLPGVTIPEG
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCHHHHHCCCCCCCCCHH
IIRRLAGACDPLKEGTAIAAEQVAKARQICDGVHLMAIRKEELIPEILDLAGIAPVQ
HHHHHHHCCCCHHCCHHHHHHHHHHHHHHHCCHHHEEHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9353932; 9384377 [H]