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The map label for this gene is hemA [H]

Identifier: 238916685

GI number: 238916685

Start: 757313

End: 758530

Strand: Direct

Name: hemA [H]

Synonym: EUBELI_00747

Alternate gene names: 238916685

Gene position: 757313-758530 (Clockwise)

Preceding gene: 238916684

Following gene: 238916686

Centisome position: 35.32

GC content: 40.07

Gene sequence:

>1218_bases
ATGCAGTTAGGATATGTAGGAATTAATTATAAGAATACAGACCTTTCAGTAAGGGACAAGATTACATTCACAGACAGCGG
GATAGCAGACTTTATGCAACAGGCAGAGGAAGCAGGTGTGAAACAGTGCATGTGCCTTTCAACATGCAACAGATGCGAAG
TGTTTTATTTGTATGAGGATGAAACATTTGTACAAGTAATGTCCGATTTATTCAATGATTATTTTGGACTTACTGATACT
AAATTAGCCGGTGTCAAATGTGGTGAAGAAGCACTGGTATATCTGTTTTGCATAGCCGCCGGACTTGAAAGCATGGTGCT
TGGAGAGGATCAGATACTAGGCCAGTTAAAGGATGCGGCAGACCTTTCAAGAACGCTTGGACACAGCGGGAAAGAACTTA
ATTATATAGTAAGAGAAGCGGTAAGCTGTGCAAAGCGGATTAAGACAGAGTACAAGGTAAGTGAAAAACCAGTATCTGTA
TGCTATGTCGGTATTCAGGAGTTAGACAGAGTATGTGGTATATCAGGAAAGCACGCGCTTGTTATAGGAAGCGGCAAAAC
AGCAGCTCTTGCCATAAGATATCTGGCAGAATATGGCGCTGATGTAACAGTGTGTTCAAGAACTTATCAGCATGCGAAGG
CGTTGCTTAAGGAGTTTTCACAGATTGAGGTTATTGCATATGATAAGAAAACAGAAGCACTTAAAAGCAGTGATATAGTT
GTCTCAGCGACTTCATCACCTCATCTGGTGATTAAATGTGCTGAATTATCAGGGGGTAAAAAGATGACACTTCTTGATCT
TGCTGCACCAAGAGATATAGAAAAATCGGCAGGTGACATTTTTGGAGTTACTCTTATTGACCTTGACAGGATAGGTGGGA
TTGTGAAGTCTAATCAGAATGAGAGGGCACATTTGTTAAAAGAAAGCCAGTGCGTGATTGATGAATATATAGCGGAAACA
AAGAAATGGCTCACATCAAGCAGAATGGATACAACTATCCAGTCGCTTGGCAAAAAATGTGATGAGATAGTACAGGATAG
CTATGATTATCTTAACCGCAAGATTGACCTTTCAGACCATGACAGGGTAATCTTAAAGAAGATTCTTAAGTCGTCATTAC
ACAGATTGTTAAAAGAACCGATTGAAGAATTGAAAAATGTGGAAGAAAATGAACAGCAGCAGTATAAAGACATGGTGGAG
AGACTGTTTGGCTTGTAG

Upstream 100 bases:

>100_bases
GTTCGTATCAGACGCACACACTAATGAGGATATCAACCGTACAATAGAGGTTATGGAAGAATTCTTCAGGAAATAATTCG
GATAATAAGTGGGAATACAG

Downstream 100 bases:

>100_bases
GGAGGATTATGCATTACAGAATAGGAACGAGAGGTTCGAAGCTGGCACTTGTCCAGTCGGAATATGTTAAGAGAAGAATG
GAAGAGGCGTATCCTGAGGA

Product: glutamyl-tRNA reductase

Products: NA

Alternate protein names: GluTR [H]

Number of amino acids: Translated: 405; Mature: 405

Protein sequence:

>405_residues
MQLGYVGINYKNTDLSVRDKITFTDSGIADFMQQAEEAGVKQCMCLSTCNRCEVFYLYEDETFVQVMSDLFNDYFGLTDT
KLAGVKCGEEALVYLFCIAAGLESMVLGEDQILGQLKDAADLSRTLGHSGKELNYIVREAVSCAKRIKTEYKVSEKPVSV
CYVGIQELDRVCGISGKHALVIGSGKTAALAIRYLAEYGADVTVCSRTYQHAKALLKEFSQIEVIAYDKKTEALKSSDIV
VSATSSPHLVIKCAELSGGKKMTLLDLAAPRDIEKSAGDIFGVTLIDLDRIGGIVKSNQNERAHLLKESQCVIDEYIAET
KKWLTSSRMDTTIQSLGKKCDEIVQDSYDYLNRKIDLSDHDRVILKKILKSSLHRLLKEPIEELKNVEENEQQQYKDMVE
RLFGL

Sequences:

>Translated_405_residues
MQLGYVGINYKNTDLSVRDKITFTDSGIADFMQQAEEAGVKQCMCLSTCNRCEVFYLYEDETFVQVMSDLFNDYFGLTDT
KLAGVKCGEEALVYLFCIAAGLESMVLGEDQILGQLKDAADLSRTLGHSGKELNYIVREAVSCAKRIKTEYKVSEKPVSV
CYVGIQELDRVCGISGKHALVIGSGKTAALAIRYLAEYGADVTVCSRTYQHAKALLKEFSQIEVIAYDKKTEALKSSDIV
VSATSSPHLVIKCAELSGGKKMTLLDLAAPRDIEKSAGDIFGVTLIDLDRIGGIVKSNQNERAHLLKESQCVIDEYIAET
KKWLTSSRMDTTIQSLGKKCDEIVQDSYDYLNRKIDLSDHDRVILKKILKSSLHRLLKEPIEELKNVEENEQQQYKDMVE
RLFGL
>Mature_405_residues
MQLGYVGINYKNTDLSVRDKITFTDSGIADFMQQAEEAGVKQCMCLSTCNRCEVFYLYEDETFVQVMSDLFNDYFGLTDT
KLAGVKCGEEALVYLFCIAAGLESMVLGEDQILGQLKDAADLSRTLGHSGKELNYIVREAVSCAKRIKTEYKVSEKPVSV
CYVGIQELDRVCGISGKHALVIGSGKTAALAIRYLAEYGADVTVCSRTYQHAKALLKEFSQIEVIAYDKKTEALKSSDIV
VSATSSPHLVIKCAELSGGKKMTLLDLAAPRDIEKSAGDIFGVTLIDLDRIGGIVKSNQNERAHLLKESQCVIDEYIAET
KKWLTSSRMDTTIQSLGKKCDEIVQDSYDYLNRKIDLSDHDRVILKKILKSSLHRLLKEPIEELKNVEENEQQQYKDMVE
RLFGL

Specific function: Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) [H]

COG id: COG0373

COG function: function code H; Glutamyl-tRNA reductase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glutamyl-tRNA reductase family [H]

Homologues:

Organism=Escherichia coli, GI1787461, Length=365, Percent_Identity=28.4931506849315, Blast_Score=141, Evalue=9e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000343
- InterPro:   IPR015896
- InterPro:   IPR015895
- InterPro:   IPR016040
- InterPro:   IPR018214
- InterPro:   IPR006151 [H]

Pfam domain/function: PF00745 GlutR_dimer; PF05201 GlutR_N; PF01488 Shikimate_DH [H]

EC number: =1.2.1.70 [H]

Molecular weight: Translated: 45192; Mature: 45192

Theoretical pI: Translated: 5.25; Mature: 5.25

Prosite motif: PS00747 GLUTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.2 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
3.2 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQLGYVGINYKNTDLSVRDKITFTDSGIADFMQQAEEAGVKQCMCLSTCNRCEVFYLYED
CCEEEEEEEEECCCCEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECC
ETFVQVMSDLFNDYFGLTDTKLAGVKCGEEALVYLFCIAAGLESMVLGEDQILGQLKDAA
CHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
DLSRTLGHSGKELNYIVREAVSCAKRIKTEYKVSEKPVSVCYVGIQELDRVCGISGKHAL
HHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCEE
VIGSGKTAALAIRYLAEYGADVTVCSRTYQHAKALLKEFSQIEVIAYDKKTEALKSSDIV
EEECCCHHHHHHHHHHHHCCCEEHHHHHHHHHHHHHHHHCCEEEEEECCHHHHHCCCCEE
VSATSSPHLVIKCAELSGGKKMTLLDLAAPRDIEKSAGDIFGVTLIDLDRIGGIVKSNQN
EEECCCCEEEEEEEECCCCCEEEEEECCCCCCHHHCCCCEEEEHEEEHHHHCHHHCCCCC
ERAHLLKESQCVIDEYIAETKKWLTSSRMDTTIQSLGKKCDEIVQDSYDYLNRKIDLSDH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
DRVILKKILKSSLHRLLKEPIEELKNVEENEQQQYKDMVERLFGL
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MQLGYVGINYKNTDLSVRDKITFTDSGIADFMQQAEEAGVKQCMCLSTCNRCEVFYLYED
CCEEEEEEEEECCCCEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECC
ETFVQVMSDLFNDYFGLTDTKLAGVKCGEEALVYLFCIAAGLESMVLGEDQILGQLKDAA
CHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
DLSRTLGHSGKELNYIVREAVSCAKRIKTEYKVSEKPVSVCYVGIQELDRVCGISGKHAL
HHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCEE
VIGSGKTAALAIRYLAEYGADVTVCSRTYQHAKALLKEFSQIEVIAYDKKTEALKSSDIV
EEECCCHHHHHHHHHHHHCCCEEHHHHHHHHHHHHHHHHCCEEEEEECCHHHHHCCCCEE
VSATSSPHLVIKCAELSGGKKMTLLDLAAPRDIEKSAGDIFGVTLIDLDRIGGIVKSNQN
EEECCCCEEEEEEEECCCCCEEEEEECCCCCCHHHCCCCEEEEHEEEHHHHCHHHCCCCC
ERAHLLKESQCVIDEYIAETKKWLTSSRMDTTIQSLGKKCDEIVQDSYDYLNRKIDLSDH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
DRVILKKILKSSLHRLLKEPIEELKNVEENEQQQYKDMVERLFGL
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA