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The map label for this gene is pdhA [H]

Identifier: 238028031

GI number: 238028031

Start: 2816574

End: 2819270

Strand: Reverse

Name: pdhA [H]

Synonym: bglu_1g24810

Alternate gene names: 238028031

Gene position: 2819270-2816574 (Counterclockwise)

Preceding gene: 238028036

Following gene: 238028030

Centisome position: 72.17

GC content: 65.37

Gene sequence:

>2697_bases
ATGTCCGCTGTACCCAACGAAGTGATGAAGTACGTCGCCGCCGAGCAGGACGACGATTCGCAAGAAACCGTCGAATGGCT
GGAGGCACTGGACGGCGTGATCTCGTCGGTCGGTCCGGGCCGAGCGCATTACCTCATCGAAAAGCAGATCGAGTTCGCCC
GCATGCATGGCGAGCATCTGCCGTTTTCCGCGAACACCCCCTATATCAACACCATCCCGGTCGAGCGTCAGGCGAAGATC
CCGGGCGATCAGGACGTCGAACACCGGATCCGCTCGTACACGCGCTGGAACGCGATCGCGATGGTGCTGCGCGCCGGCAA
GGACACCAACGTCGGCGGCCACATCGCCTCGTTCGCGTCGGCCGCGACGCTCTATGACGTCGGCTTCAACCATTTCTGGC
ACGCGCCGTCCGAAGCGCACGGCGGTGACCTCGTGTTCGTGCAGGGCCACTCGTCGCCGGGCGTCTATTCGCGCGCGTTC
CTGCTCGGCCGCCTGAGCGAGGAGCAGCTCGACAACTTCCGCCAGGAAGTCGGCGGCAACGGCATCTCGTCGTATCCGCA
CCCGTGGCTGATGCCGGACTTCTGGCAGTTCCCGACGGTGTCGATGGGCCTCGGCCCGATTATGGCGATCTACCAGGCGC
GCTTCATGAAGTACCTGGAGGCGCGCGGCATCACCAAGACCGCGGGCCGCAAGGTTTGGGCCTTCCTCGGCGACGGCGAG
ACCGACGAGCCGGAATCGCTCGGCGCGATCGGCATGGCGAGCCGCGAGCGGCTCGACAACCTCGTGTTCGTGATCAACTG
CAACCTGCAGCGCCTGGACGGTCCGGTGCGCGGCAACGGCAAGATCATCCAGGAACTCGAATCGGAATTCCGCGGTGCCG
GCTGGAACGTCATCAAGGTGATCTGGGGCAGCCGCTGGGATTCGCTGCTGGCCCGCGACAAGTCGGGCGCGCTGATGCGC
CGCATGATGGAAGTCGTCGACGGCGAATACCAGACCTACAAGTCGGAGTCCGGCGCGTTCGTGCGCGAGCACTTCTTCAA
CACGCCGGAACTGAAGGCGATGGTCGCCGACTGGTCGGACGACGACATCTGGAACCTGAACCGCGGCGGCCATGATCCGC
ACAAGATCTACGCGGCGTTCCACGAGGCCAGCAACACCAAGGGCGCGCCGACCGTGATCCTCGCCAAGACGATCAAGGGC
TACGGGATGGGCGAAGCCGGCCAGGCGATGAACATCACCCACCAGCAGAAGAAGCTGCCGGTGGAACAGCTCAAGCGCTT
CCGCGACCAGTTCCGTCTGCCGATCAGCGACGACGTGATCGCCGACGTGCCCTACCTGAAGTTCGAGGAAGGCTCGAAGG
AACTCGAGTACATGCGCGCGCACCGCCAGGCGCTCGGCGGCTACCTGCCGCAGCGCCGCCAGAAGGCGCAGTCGCTGCCG
GTGCCGGCGCTCGACGCGTTCGAGCCGCTGCTCAAGGGCACGGGCGAGGGCCGCGAGATATCGACCACGATGGCGTTCGT
GCGGATCCTGAACATCCTGCTGAAGGACAAGGCGCTCGGCAAGCGCGTCGTGCCGATCGTGCCGGACGAGTCGCGTACCT
TCGGCATGGAAGGCCTGTTCCGCCAGATCGGCATCTGGAACCAGCAGGGCCAGAAGTACGTGCCGGAAGATTCCGACCAG
CTGATGTTCTACAAGGAATCGGAAACCGGCCAGATCCTGCAGGAAGGCATCAACGAAGCGGGCGGCATGTGCGACTGGAT
CGCGGCGGCGACCTCGTATTCGACGCACGGCGAGATCATGGTGCCGTTCTACATCTTCTATTCGATGTTCGGCTTCCAGC
GCATCGGCGACCTGGCCTGGGCGGCGGGCGACATGCGCTCGCGCGGCTTCCTGCTGGGCGGCACTGCCGGGCGTACCACG
CTCAACGGTGAAGGCCTGCAGCACGAAGACGGCCACTCGCTGCTGTGGGCGGCCTCGGTGCCGAACTGCGTGAGCTACGA
CCCGACCTTCGGCTACGAGCTCGCCGTGATCATCCAGAACGGCCTGCAGCGCATGGTGGCCGATCAGGAGGACGTGTACT
ACTACGTCACGGTGATGAACGAGAACTACGAGCACCCGGCGATTCCGCAGGGTGAGCACGTGGCGGCCGACATCATCAAG
GGCATGTACGCGTTCCGCAAGGCCGAGGCCGACCAGAAGGCGCCCCGCGTGCAACTGCTCGGCGCGGGCACGATCTTCAA
CGAAGTGATCGCCGCCGCCGACCTGCTGAAGAACGACTGGGGCGTCGCCGCCGATCTCTGGAGCGTGCCGAGCTTCACCG
AGCTCGCGCGCGAGGGCCACGAGGTCGAGCGCTGGAACCTGCTGAACCCCACCGAGGAGCGCCGCCTGTCGCATGTCCAG
AGGCTGCTGAAGGACACGCAGGGCCCGGTGATCGCCTCGACCGACTACGTGCGCGCGCTGGCCGACCAGATCCGCGGCCA
GATCGATCGCCGTTACGTGGTGCTCGGCACCGACGGCTATGGCCGCTCGGACACGCGCAAGGCGCTGCGCCACTTCTTCG
AGGTGGATCGCCACTGGGTGACCGTCGCCGCGCTGAACGCGCTGGCCGACGAAGGCACGATCGACCGCAAGGTGGTCGCC
GAGGCGATCAAGAAGTACGGCCTCGATCCGTCGAAACCCAATCCGATGACGGTTTAA

Upstream 100 bases:

>100_bases
TGGCCAGCCTCTTTACAATCCGCCGGGAGCTTGCCGCAGCCGCCGGAATCGGGTCGTCTGCACGCAGCGCGATCTCACAC
TCAGGACCCAGGAGACGAGC

Downstream 100 bases:

>100_bases
ACGCATACGTGCCATGTCACGCCGCGCCGCCCGACCAGGGCGGCGCGGCCCAGGAGACTTTTACAGATGAGTCAAGCGAT
CGAAGTCAAGGTGCCGGATA

Product: pyruvate dehydrogenase subunit E1

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 898; Mature: 897

Protein sequence:

>898_residues
MSAVPNEVMKYVAAEQDDDSQETVEWLEALDGVISSVGPGRAHYLIEKQIEFARMHGEHLPFSANTPYINTIPVERQAKI
PGDQDVEHRIRSYTRWNAIAMVLRAGKDTNVGGHIASFASAATLYDVGFNHFWHAPSEAHGGDLVFVQGHSSPGVYSRAF
LLGRLSEEQLDNFRQEVGGNGISSYPHPWLMPDFWQFPTVSMGLGPIMAIYQARFMKYLEARGITKTAGRKVWAFLGDGE
TDEPESLGAIGMASRERLDNLVFVINCNLQRLDGPVRGNGKIIQELESEFRGAGWNVIKVIWGSRWDSLLARDKSGALMR
RMMEVVDGEYQTYKSESGAFVREHFFNTPELKAMVADWSDDDIWNLNRGGHDPHKIYAAFHEASNTKGAPTVILAKTIKG
YGMGEAGQAMNITHQQKKLPVEQLKRFRDQFRLPISDDVIADVPYLKFEEGSKELEYMRAHRQALGGYLPQRRQKAQSLP
VPALDAFEPLLKGTGEGREISTTMAFVRILNILLKDKALGKRVVPIVPDESRTFGMEGLFRQIGIWNQQGQKYVPEDSDQ
LMFYKESETGQILQEGINEAGGMCDWIAAATSYSTHGEIMVPFYIFYSMFGFQRIGDLAWAAGDMRSRGFLLGGTAGRTT
LNGEGLQHEDGHSLLWAASVPNCVSYDPTFGYELAVIIQNGLQRMVADQEDVYYYVTVMNENYEHPAIPQGEHVAADIIK
GMYAFRKAEADQKAPRVQLLGAGTIFNEVIAAADLLKNDWGVAADLWSVPSFTELAREGHEVERWNLLNPTEERRLSHVQ
RLLKDTQGPVIASTDYVRALADQIRGQIDRRYVVLGTDGYGRSDTRKALRHFFEVDRHWVTVAALNALADEGTIDRKVVA
EAIKKYGLDPSKPNPMTV

Sequences:

>Translated_898_residues
MSAVPNEVMKYVAAEQDDDSQETVEWLEALDGVISSVGPGRAHYLIEKQIEFARMHGEHLPFSANTPYINTIPVERQAKI
PGDQDVEHRIRSYTRWNAIAMVLRAGKDTNVGGHIASFASAATLYDVGFNHFWHAPSEAHGGDLVFVQGHSSPGVYSRAF
LLGRLSEEQLDNFRQEVGGNGISSYPHPWLMPDFWQFPTVSMGLGPIMAIYQARFMKYLEARGITKTAGRKVWAFLGDGE
TDEPESLGAIGMASRERLDNLVFVINCNLQRLDGPVRGNGKIIQELESEFRGAGWNVIKVIWGSRWDSLLARDKSGALMR
RMMEVVDGEYQTYKSESGAFVREHFFNTPELKAMVADWSDDDIWNLNRGGHDPHKIYAAFHEASNTKGAPTVILAKTIKG
YGMGEAGQAMNITHQQKKLPVEQLKRFRDQFRLPISDDVIADVPYLKFEEGSKELEYMRAHRQALGGYLPQRRQKAQSLP
VPALDAFEPLLKGTGEGREISTTMAFVRILNILLKDKALGKRVVPIVPDESRTFGMEGLFRQIGIWNQQGQKYVPEDSDQ
LMFYKESETGQILQEGINEAGGMCDWIAAATSYSTHGEIMVPFYIFYSMFGFQRIGDLAWAAGDMRSRGFLLGGTAGRTT
LNGEGLQHEDGHSLLWAASVPNCVSYDPTFGYELAVIIQNGLQRMVADQEDVYYYVTVMNENYEHPAIPQGEHVAADIIK
GMYAFRKAEADQKAPRVQLLGAGTIFNEVIAAADLLKNDWGVAADLWSVPSFTELAREGHEVERWNLLNPTEERRLSHVQ
RLLKDTQGPVIASTDYVRALADQIRGQIDRRYVVLGTDGYGRSDTRKALRHFFEVDRHWVTVAALNALADEGTIDRKVVA
EAIKKYGLDPSKPNPMTV
>Mature_897_residues
SAVPNEVMKYVAAEQDDDSQETVEWLEALDGVISSVGPGRAHYLIEKQIEFARMHGEHLPFSANTPYINTIPVERQAKIP
GDQDVEHRIRSYTRWNAIAMVLRAGKDTNVGGHIASFASAATLYDVGFNHFWHAPSEAHGGDLVFVQGHSSPGVYSRAFL
LGRLSEEQLDNFRQEVGGNGISSYPHPWLMPDFWQFPTVSMGLGPIMAIYQARFMKYLEARGITKTAGRKVWAFLGDGET
DEPESLGAIGMASRERLDNLVFVINCNLQRLDGPVRGNGKIIQELESEFRGAGWNVIKVIWGSRWDSLLARDKSGALMRR
MMEVVDGEYQTYKSESGAFVREHFFNTPELKAMVADWSDDDIWNLNRGGHDPHKIYAAFHEASNTKGAPTVILAKTIKGY
GMGEAGQAMNITHQQKKLPVEQLKRFRDQFRLPISDDVIADVPYLKFEEGSKELEYMRAHRQALGGYLPQRRQKAQSLPV
PALDAFEPLLKGTGEGREISTTMAFVRILNILLKDKALGKRVVPIVPDESRTFGMEGLFRQIGIWNQQGQKYVPEDSDQL
MFYKESETGQILQEGINEAGGMCDWIAAATSYSTHGEIMVPFYIFYSMFGFQRIGDLAWAAGDMRSRGFLLGGTAGRTTL
NGEGLQHEDGHSLLWAASVPNCVSYDPTFGYELAVIIQNGLQRMVADQEDVYYYVTVMNENYEHPAIPQGEHVAADIIKG
MYAFRKAEADQKAPRVQLLGAGTIFNEVIAAADLLKNDWGVAADLWSVPSFTELAREGHEVERWNLLNPTEERRLSHVQR
LLKDTQGPVIASTDYVRALADQIRGQIDRRYVVLGTDGYGRSDTRKALRHFFEVDRHWVTVAALNALADEGTIDRKVVAE
AIKKYGLDPSKPNPMTV

Specific function: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components:pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydroge

COG id: COG2609

COG function: function code C; Pyruvate dehydrogenase complex, dehydrogenase (E1) component

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1786304, Length=885, Percent_Identity=59.5480225988701, Blast_Score=1078, Evalue=0.0,

Paralogues:

None

Copy number: 1140 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 400 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). 6,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004660
- InterPro:   IPR009014
- InterPro:   IPR015941
- InterPro:   IPR005474 [H]

Pfam domain/function: PF00456 Transketolase_N [H]

EC number: =1.2.4.1 [H]

Molecular weight: Translated: 100510; Mature: 100379

Theoretical pI: Translated: 5.86; Mature: 5.86

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAVPNEVMKYVAAEQDDDSQETVEWLEALDGVISSVGPGRAHYLIEKQIEFARMHGEHL
CCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCC
PFSANTPYINTIPVERQAKIPGDQDVEHRIRSYTRWNAIAMVLRAGKDTNVGGHIASFAS
CCCCCCCEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHH
AATLYDVGFNHFWHAPSEAHGGDLVFVQGHSSPGVYSRAFLLGRLSEEQLDNFRQEVGGN
HHHHHHCCHHHHCCCCCCCCCCCEEEEECCCCCCHHHHHHHHHCCCHHHHHHHHHHHCCC
GISSYPHPWLMPDFWQFPTVSMGLGPIMAIYQARFMKYLEARGITKTAGRKVWAFLGDGE
CCCCCCCCCCCCCCCCCCCCHHCHHHHHHHHHHHHHHHHHHCCCCHHCCCEEEEEECCCC
TDEPESLGAIGMASRERLDNLVFVINCNLQRLDGPVRGNGKIIQELESEFRGAGWNVIKV
CCCCHHHCHHCHHHHHHHCCEEEEEECCHHHCCCCCCCCCHHHHHHHHHHCCCCCEEEEE
IWGSRWDSLLARDKSGALMRRMMEVVDGEYQTYKSESGAFVREHFFNTPELKAMVADWSD
ECCCCHHHHHHCCCCHHHHHHHHHHHCCHHHHHCCCCCCHHHHHCCCCCHHHEEEECCCC
DDIWNLNRGGHDPHKIYAAFHEASNTKGAPTVILAKTIKGYGMGEAGQAMNITHQQKKLP
CCCEECCCCCCCHHHHHHHHHHHCCCCCCCEEEEEEHHCCCCCCCCCCCCCCCHHHHCCC
VEQLKRFRDQFRLPISDDVIADVPYLKFEEGSKELEYMRAHRQALGGYLPQRRQKAQSLP
HHHHHHHHHHHCCCCCCCHHCCCCCEEECCCCHHHHHHHHHHHHHCCCCHHHHHHHHCCC
VPALDAFEPLLKGTGEGREISTTMAFVRILNILLKDKALGKRVVPIVPDESRTFGMEGLF
CCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCEECCCCCCCCCHHHHH
RQIGIWNQQGQKYVPEDSDQLMFYKESETGQILQEGINEAGGMCDWIAAATSYSTHGEIM
HHHCCCCCCCCCCCCCCCCCEEEEECCCHHHHHHHHHHHHCCHHHHHHHHCCCCCCCCEE
VPFYIFYSMFGFQRIGDLAWAAGDMRSRGFLLGGTAGRTTLNGEGLQHEDGHSLLWAASV
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCCCEECCCCCCCCCCCEEEEECCC
PNCVSYDPTFGYELAVIIQNGLQRMVADQEDVYYYVTVMNENYEHPAIPQGEHVAADIIK
CCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEEEEEECCCCCCCCCCCCCHHHHHHHH
GMYAFRKAEADQKAPRVQLLGAGTIFNEVIAAADLLKNDWGVAADLWSVPSFTELAREGH
HHHHHHHHCCHHCCCCEEEEECHHHHHHHHHHHHHHHCCCCCHHHHHCCCCHHHHHHCCC
EVERWNLLNPTEERRLSHVQRLLKDTQGPVIASTDYVRALADQIRGQIDRRYVVLGTDGY
CCCCCCCCCCHHHHHHHHHHHHHHHCCCCEEECHHHHHHHHHHHHHCCCCEEEEEECCCC
GRSDTRKALRHFFEVDRHWVTVAALNALADEGTIDRKVVAEAIKKYGLDPSKPNPMTV
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure 
SAVPNEVMKYVAAEQDDDSQETVEWLEALDGVISSVGPGRAHYLIEKQIEFARMHGEHL
CCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCC
PFSANTPYINTIPVERQAKIPGDQDVEHRIRSYTRWNAIAMVLRAGKDTNVGGHIASFAS
CCCCCCCEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHH
AATLYDVGFNHFWHAPSEAHGGDLVFVQGHSSPGVYSRAFLLGRLSEEQLDNFRQEVGGN
HHHHHHCCHHHHCCCCCCCCCCCEEEEECCCCCCHHHHHHHHHCCCHHHHHHHHHHHCCC
GISSYPHPWLMPDFWQFPTVSMGLGPIMAIYQARFMKYLEARGITKTAGRKVWAFLGDGE
CCCCCCCCCCCCCCCCCCCCHHCHHHHHHHHHHHHHHHHHHCCCCHHCCCEEEEEECCCC
TDEPESLGAIGMASRERLDNLVFVINCNLQRLDGPVRGNGKIIQELESEFRGAGWNVIKV
CCCCHHHCHHCHHHHHHHCCEEEEEECCHHHCCCCCCCCCHHHHHHHHHHCCCCCEEEEE
IWGSRWDSLLARDKSGALMRRMMEVVDGEYQTYKSESGAFVREHFFNTPELKAMVADWSD
ECCCCHHHHHHCCCCHHHHHHHHHHHCCHHHHHCCCCCCHHHHHCCCCCHHHEEEECCCC
DDIWNLNRGGHDPHKIYAAFHEASNTKGAPTVILAKTIKGYGMGEAGQAMNITHQQKKLP
CCCEECCCCCCCHHHHHHHHHHHCCCCCCCEEEEEEHHCCCCCCCCCCCCCCCHHHHCCC
VEQLKRFRDQFRLPISDDVIADVPYLKFEEGSKELEYMRAHRQALGGYLPQRRQKAQSLP
HHHHHHHHHHHCCCCCCCHHCCCCCEEECCCCHHHHHHHHHHHHHCCCCHHHHHHHHCCC
VPALDAFEPLLKGTGEGREISTTMAFVRILNILLKDKALGKRVVPIVPDESRTFGMEGLF
CCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCEECCCCCCCCCHHHHH
RQIGIWNQQGQKYVPEDSDQLMFYKESETGQILQEGINEAGGMCDWIAAATSYSTHGEIM
HHHCCCCCCCCCCCCCCCCCEEEEECCCHHHHHHHHHHHHCCHHHHHHHHCCCCCCCCEE
VPFYIFYSMFGFQRIGDLAWAAGDMRSRGFLLGGTAGRTTLNGEGLQHEDGHSLLWAASV
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCCCEECCCCCCCCCCCEEEEECCC
PNCVSYDPTFGYELAVIIQNGLQRMVADQEDVYYYVTVMNENYEHPAIPQGEHVAADIIK
CCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEEEEEECCCCCCCCCCCCCHHHHHHHH
GMYAFRKAEADQKAPRVQLLGAGTIFNEVIAAADLLKNDWGVAADLWSVPSFTELAREGH
HHHHHHHHCCHHCCCCEEEEECHHHHHHHHHHHHHHHCCCCCHHHHHCCCCHHHHHHCCC
EVERWNLLNPTEERRLSHVQRLLKDTQGPVIASTDYVRALADQIRGQIDRRYVVLGTDGY
CCCCCCCCCCHHHHHHHHHHHHHHHCCCCEEECHHHHHHHHHHHHHCCCCEEEEEECCCC
GRSDTRKALRHFFEVDRHWVTVAALNALADEGTIDRKVVAEAIKKYGLDPSKPNPMTV
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8021225 [H]