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The map label for this gene is dinB [H]

Identifier: 238028036

GI number: 238028036

Start: 2826273

End: 2827757

Strand: Reverse

Name: dinB [H]

Synonym: bglu_1g24860

Alternate gene names: 238028036

Gene position: 2827757-2826273 (Counterclockwise)

Preceding gene: 238028040

Following gene: 238028031

Centisome position: 72.39

GC content: 70.91

Gene sequence:

>1485_bases
ATGGCGGGTAAATCCCGATCGCCATTTGCTGCGGTTGATTATCCGCGGCGCCTGTTCGTCTGCGTAAGCGGGGCGCCTTT
GCGCCCGCGCCGGCGGCGCCGGGAAAAATTTCGCGTCTGCAACCTTCGGTCAGGTCCGCGCGCGCTTTCACGTGATAATG
CTGTTTTGCCCCGCCCCGACACCGTGAGTTCCCCCGCGCCCGCTCCGGATTCCGTCGCGCCGGCCCTTGCCGCGGCCGGC
GCGCACGCGTTCGTGCGCAAGATCATTCATCTCGACTGCGACTGCTTCTACGCGTCGGTCGAGATGCGCGACGACCCCTC
GCTGCGCGGCCGTCCGCTCGCGGTGGGCGGCCGGCCCGACCGGCGCGGCGTGATCGCCACCTGCAACTACGAGGCGCGGC
GCTACGGCGTGCATTCGGCGATGTCGTCGGCGCTGGCGATGCGCAAGTGCCCGGACCTGCTGATCCTGCCGCCGTCGATG
GACAAGTACCGGATCGCCTCGCGCGCGATCATGGAGATCTATCGCGACTACACGGCCGAGGTCGAGCCGCTCTCGCTCGA
CGAGGCCTACCTCGACGTGAGCCGCACCGGGCGCTGCCAGGGCAGCGCGACGCTGATCGCGCGCGAGATCCGCGCGCGCG
TGCGCGACACGGTGGGCGTGACGGTCTCGGCCGGGGTCGCGCCGAACAAGTTCGTCGCCAAGATCGCTTCCGACTGGAAC
AAGCCCGACGGCCTGTTCGTGGTGCGGCCGCACGAGGTGGACGCGTTCGTGGCGGCGCTGCCGGTGCGCAAGCTGTTCGG
CGTCGGCCGCGTCACCGCGGGGCGGCTCGAGCGGCTCGGCATCGAGACCTGCGCGCAACTGCGCGAATGGTCGCTGTTCG
ACCTGCATCGCGAGTTCGGCGCGTTCGGCCGGCGCCTGCACGAGTTGTCGCACGGCATCGACGAGCGCCGCGTGCGCGCC
GACCGCGAGCGCAAGTCGGTCAGCGTCGAGACCACCTATGTCCACGATCTCACCACGCTCGAACAGTGCGCCGCGGAAAT
GCGCCGGCTGGTGCCGCAGCTCGACGCGCGCATCGAGCGCGCCGGCGCGCGCCGGCTGGTCCGCAAGCTCTACGTGAAGA
TCCGCTTTGCCGATTTCCAGCGCACCACGGTGGAATGCGTGGCCGACGCGACCGACGTGCAGACCGCCATCGCGCTGCTG
GGCAAGGGGCTCGCACGGCGGCCGCAGGCGGTGCGGCTGCTCGGCGTGGGCGTGCGCGTCGACGAGGACACGGCCGAGCG
CCACGGCCAGATCGCGTTGTTCGACGACGAAGCGGACGCGCACGAACGGGAGGGCGAGGCGGGGGCGGGCGTCATTGACG
CCGTGGTCGACGCGGCCGACCAGAGCAACCCAGCAGATGCGCCGGCGAGCCTTGCCGGCGACGTTGCCGATGCAGGCGAC
CAAGCGCGCGAGAACGACGGCCCCGCCGAACCCGGCTCGGCATGA

Upstream 100 bases:

>100_bases
AATCAAGATAATTGAGTAAATAATGCGTGGATAAACGCCTGGTCAGACGTCTAATCTGCAATATTGAACGAATTAAATAA
GGGTTCGATTTTGAATTCGA

Downstream 100 bases:

>100_bases
AAGAACGGCGCCCGTATGACCGGGCGCCGTTCGGTACAGCGAGGCGCGGCGGGCCGGCAGCCCGCGCCCGCCCGGCGAAT
CAGGCGGCACGGCTGCCCGG

Product: DNA polymerase IV

Products: NA

Alternate protein names: Pol IV [H]

Number of amino acids: Translated: 494; Mature: 493

Protein sequence:

>494_residues
MAGKSRSPFAAVDYPRRLFVCVSGAPLRPRRRRREKFRVCNLRSGPRALSRDNAVLPRPDTVSSPAPAPDSVAPALAAAG
AHAFVRKIIHLDCDCFYASVEMRDDPSLRGRPLAVGGRPDRRGVIATCNYEARRYGVHSAMSSALAMRKCPDLLILPPSM
DKYRIASRAIMEIYRDYTAEVEPLSLDEAYLDVSRTGRCQGSATLIAREIRARVRDTVGVTVSAGVAPNKFVAKIASDWN
KPDGLFVVRPHEVDAFVAALPVRKLFGVGRVTAGRLERLGIETCAQLREWSLFDLHREFGAFGRRLHELSHGIDERRVRA
DRERKSVSVETTYVHDLTTLEQCAAEMRRLVPQLDARIERAGARRLVRKLYVKIRFADFQRTTVECVADATDVQTAIALL
GKGLARRPQAVRLLGVGVRVDEDTAERHGQIALFDDEADAHEREGEAGAGVIDAVVDAADQSNPADAPASLAGDVADAGD
QARENDGPAEPGSA

Sequences:

>Translated_494_residues
MAGKSRSPFAAVDYPRRLFVCVSGAPLRPRRRRREKFRVCNLRSGPRALSRDNAVLPRPDTVSSPAPAPDSVAPALAAAG
AHAFVRKIIHLDCDCFYASVEMRDDPSLRGRPLAVGGRPDRRGVIATCNYEARRYGVHSAMSSALAMRKCPDLLILPPSM
DKYRIASRAIMEIYRDYTAEVEPLSLDEAYLDVSRTGRCQGSATLIAREIRARVRDTVGVTVSAGVAPNKFVAKIASDWN
KPDGLFVVRPHEVDAFVAALPVRKLFGVGRVTAGRLERLGIETCAQLREWSLFDLHREFGAFGRRLHELSHGIDERRVRA
DRERKSVSVETTYVHDLTTLEQCAAEMRRLVPQLDARIERAGARRLVRKLYVKIRFADFQRTTVECVADATDVQTAIALL
GKGLARRPQAVRLLGVGVRVDEDTAERHGQIALFDDEADAHEREGEAGAGVIDAVVDAADQSNPADAPASLAGDVADAGD
QARENDGPAEPGSA
>Mature_493_residues
AGKSRSPFAAVDYPRRLFVCVSGAPLRPRRRRREKFRVCNLRSGPRALSRDNAVLPRPDTVSSPAPAPDSVAPALAAAGA
HAFVRKIIHLDCDCFYASVEMRDDPSLRGRPLAVGGRPDRRGVIATCNYEARRYGVHSAMSSALAMRKCPDLLILPPSMD
KYRIASRAIMEIYRDYTAEVEPLSLDEAYLDVSRTGRCQGSATLIAREIRARVRDTVGVTVSAGVAPNKFVAKIASDWNK
PDGLFVVRPHEVDAFVAALPVRKLFGVGRVTAGRLERLGIETCAQLREWSLFDLHREFGAFGRRLHELSHGIDERRVRAD
RERKSVSVETTYVHDLTTLEQCAAEMRRLVPQLDARIERAGARRLVRKLYVKIRFADFQRTTVECVADATDVQTAIALLG
KGLARRPQAVRLLGVGVRVDEDTAERHGQIALFDDEADAHEREGEAGAGVIDAVVDAADQSNPADAPASLAGDVADAGDQ
ARENDGPAEPGSA

Specific function: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits

COG id: COG0389

COG function: function code L; Nucleotidyltransferase/DNA polymerase involved in DNA repair

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 umuC domain [H]

Homologues:

Organism=Homo sapiens, GI84043967, Length=341, Percent_Identity=29.3255131964809, Blast_Score=161, Evalue=1e-39,
Organism=Homo sapiens, GI7706681, Length=342, Percent_Identity=29.2397660818713, Blast_Score=161, Evalue=1e-39,
Organism=Homo sapiens, GI154350220, Length=315, Percent_Identity=29.5238095238095, Blast_Score=130, Evalue=2e-30,
Organism=Homo sapiens, GI7705344, Length=121, Percent_Identity=43.801652892562, Blast_Score=119, Evalue=7e-27,
Organism=Homo sapiens, GI5729982, Length=366, Percent_Identity=27.8688524590164, Blast_Score=107, Evalue=3e-23,
Organism=Escherichia coli, GI1786425, Length=351, Percent_Identity=48.1481481481481, Blast_Score=319, Evalue=3e-88,
Organism=Escherichia coli, GI1787432, Length=219, Percent_Identity=28.7671232876712, Blast_Score=78, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI193205700, Length=425, Percent_Identity=27.5294117647059, Blast_Score=135, Evalue=4e-32,
Organism=Caenorhabditis elegans, GI17537959, Length=286, Percent_Identity=30.4195804195804, Blast_Score=120, Evalue=2e-27,
Organism=Caenorhabditis elegans, GI193205702, Length=370, Percent_Identity=25.9459459459459, Blast_Score=96, Evalue=4e-20,
Organism=Caenorhabditis elegans, GI115534089, Length=124, Percent_Identity=38.7096774193548, Blast_Score=79, Evalue=6e-15,
Organism=Saccharomyces cerevisiae, GI6324921, Length=310, Percent_Identity=26.7741935483871, Blast_Score=78, Evalue=3e-15,
Organism=Drosophila melanogaster, GI19923006, Length=350, Percent_Identity=25.7142857142857, Blast_Score=129, Evalue=5e-30,
Organism=Drosophila melanogaster, GI21355641, Length=296, Percent_Identity=30.0675675675676, Blast_Score=122, Evalue=8e-28,
Organism=Drosophila melanogaster, GI24644984, Length=296, Percent_Identity=30.0675675675676, Blast_Score=122, Evalue=8e-28,
Organism=Drosophila melanogaster, GI24668444, Length=123, Percent_Identity=34.9593495934959, Blast_Score=72, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017962
- InterPro:   IPR017961
- InterPro:   IPR001126
- InterPro:   IPR017963
- InterPro:   IPR022880 [H]

Pfam domain/function: PF00817 IMS [H]

EC number: =2.7.7.7 [H]

Molecular weight: Translated: 54087; Mature: 53956

Theoretical pI: Translated: 8.82; Mature: 8.82

Prosite motif: PS50173 UMUC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAGKSRSPFAAVDYPRRLFVCVSGAPLRPRRRRREKFRVCNLRSGPRALSRDNAVLPRPD
CCCCCCCCCEECCCCCEEEEEECCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCC
TVSSPAPAPDSVAPALAAAGAHAFVRKIIHLDCDCFYASVEMRDDPSLRGRPLAVGGRPD
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCCCCCEEEECCCCC
RRGVIATCNYEARRYGVHSAMSSALAMRKCPDLLILPPSMDKYRIASRAIMEIYRDYTAE
CCCEEEEECCHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCHHHHHHHHHHHHHHHHCCC
VEPLSLDEAYLDVSRTGRCQGSATLIAREIRARVRDTVGVTVSAGVAPNKFVAKIASDWN
CCCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCEEEECCCCCHHHHHHHHHCCC
KPDGLFVVRPHEVDAFVAALPVRKLFGVGRVTAGRLERLGIETCAQLREWSLFDLHREFG
CCCCEEEECCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHH
AFGRRLHELSHGIDERRVRADRERKSVSVETTYVHDLTTLEQCAAEMRRLVPQLDARIER
HHHHHHHHHHCCHHHHHHHHHHHHHCEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHH
AGARRLVRKLYVKIRFADFQRTTVECVADATDVQTAIALLGKGLARRPQAVRLLGVGVRV
HHHHHHHHHHHHHEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECEEE
DEDTAERHGQIALFDDEADAHEREGEAGAGVIDAVVDAADQSNPADAPASLAGDVADAGD
CCHHHHHCCCEEEECCCCCHHHCCCCCCCHHHHHHHHHHCCCCCCCCCHHHHCCHHHCCC
QARENDGPAEPGSA
HHHCCCCCCCCCCC
>Mature Secondary Structure 
AGKSRSPFAAVDYPRRLFVCVSGAPLRPRRRRREKFRVCNLRSGPRALSRDNAVLPRPD
CCCCCCCCEECCCCCEEEEEECCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCC
TVSSPAPAPDSVAPALAAAGAHAFVRKIIHLDCDCFYASVEMRDDPSLRGRPLAVGGRPD
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCCCCCEEEECCCCC
RRGVIATCNYEARRYGVHSAMSSALAMRKCPDLLILPPSMDKYRIASRAIMEIYRDYTAE
CCCEEEEECCHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCHHHHHHHHHHHHHHHHCCC
VEPLSLDEAYLDVSRTGRCQGSATLIAREIRARVRDTVGVTVSAGVAPNKFVAKIASDWN
CCCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCEEEECCCCCHHHHHHHHHCCC
KPDGLFVVRPHEVDAFVAALPVRKLFGVGRVTAGRLERLGIETCAQLREWSLFDLHREFG
CCCCEEEECCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHH
AFGRRLHELSHGIDERRVRADRERKSVSVETTYVHDLTTLEQCAAEMRRLVPQLDARIER
HHHHHHHHHHCCHHHHHHHHHHHHHCEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHH
AGARRLVRKLYVKIRFADFQRTTVECVADATDVQTAIALLGKGLARRPQAVRLLGVGVRV
HHHHHHHHHHHHHEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECEEE
DEDTAERHGQIALFDDEADAHEREGEAGAGVIDAVVDAADQSNPADAPASLAGDVADAGD
CCHHHHHCCCEEEECCCCCHHHCCCCCCCHHHHHHHHHHCCCCCCCCCHHHHCCHHHCCC
QARENDGPAEPGSA
HHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11823852 [H]