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The map label for this gene is lutA

Identifier: 222150422

GI number: 222150422

Start: 178043

End: 178780

Strand: Direct

Name: lutA

Synonym: MCCL_0172

Alternate gene names: 222150422

Gene position: 178043-178780 (Clockwise)

Preceding gene: 222150421

Following gene: 222150423

Centisome position: 8.47

GC content: 39.16

Gene sequence:

>738_bases
ATGAAAGTAAGCTTATTCAGTACGTGTTTAGTAGATGTATTCGAAAAACGTGTGGGTATTGCAACAGTGGAATTGTTAGA
GAAACTAGGATGTGAAGTAGATTTCCCGGCAGCACAAGTATGTTGTGGGCAACCTGCTTATAACTCAGGGTATCACGAGG
AAACGAAGAAAGCTGCGAAGAATATGATTAAAGCTTTCGAGCAATCAGAAGTTGTCGTTGCACCTTCAGGATCATGTGTA
ACGATGTTTAAACATTATCCAGATCTATTCAAAAACGATGCAAAGTGGCAAGCACGTGCACAAGAACTTGCAGATAAAAC
GTATGAAGTTACGCAGTTCATTGTAGAAGTGTTAGGTATTACAAATGTAGGAGCAAAACTTGATGGTGTAGCTACAATTC
ATCCATCTTGCCATATGACACGTCTGTTAGGTAATGTGACTGCACCTGCTAAACTTCTGAACGAAGTAGAAGGACTAGAA
GTTGTTGAATTACCTAAATACTACAATTGTTGTGGTTTCGGTGGAACATTTGCTGTTAAAATGAGCGATGTTTCAGGTGA
AATGGTAGATGAAAAAGTAGATTGCATCGTTGAAAGTGGTGCAGACTATTTAGTTGGCGGAGACTGCAGTTGTTTGATGA
ATATTGATGGTAGATTAAGACGTCGTGGTGTTGATGTGAAAGCTGTACATATCATTGAAATCTTAAATAACCAAGTTGAG
GCGGTGACTACACGATGA

Upstream 100 bases:

>100_bases
AAAAACGTTGCAATAGAATAGAACTATTGGTCACCGAGTCATATGATGACTGTTTAATTTTCAGCTGTGGGCACACTGAA
AAAAATTGGGGGGTATAACT

Downstream 100 bases:

>100_bases
GTATGAGAATAGGTAACGAAACGTTTAAGCAGGCAGTTAAGACGGAACTTAAAGATGACTTCATGCGTGGTGCTGTGAGT
AGTGCACAAGATAGATTAAG

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 245; Mature: 245

Protein sequence:

>245_residues
MKVSLFSTCLVDVFEKRVGIATVELLEKLGCEVDFPAAQVCCGQPAYNSGYHEETKKAAKNMIKAFEQSEVVVAPSGSCV
TMFKHYPDLFKNDAKWQARAQELADKTYEVTQFIVEVLGITNVGAKLDGVATIHPSCHMTRLLGNVTAPAKLLNEVEGLE
VVELPKYYNCCGFGGTFAVKMSDVSGEMVDEKVDCIVESGADYLVGGDCSCLMNIDGRLRRRGVDVKAVHIIEILNNQVE
AVTTR

Sequences:

>Translated_245_residues
MKVSLFSTCLVDVFEKRVGIATVELLEKLGCEVDFPAAQVCCGQPAYNSGYHEETKKAAKNMIKAFEQSEVVVAPSGSCV
TMFKHYPDLFKNDAKWQARAQELADKTYEVTQFIVEVLGITNVGAKLDGVATIHPSCHMTRLLGNVTAPAKLLNEVEGLE
VVELPKYYNCCGFGGTFAVKMSDVSGEMVDEKVDCIVESGADYLVGGDCSCLMNIDGRLRRRGVDVKAVHIIEILNNQVE
AVTTR
>Mature_245_residues
MKVSLFSTCLVDVFEKRVGIATVELLEKLGCEVDFPAAQVCCGQPAYNSGYHEETKKAAKNMIKAFEQSEVVVAPSGSCV
TMFKHYPDLFKNDAKWQARAQELADKTYEVTQFIVEVLGITNVGAKLDGVATIHPSCHMTRLLGNVTAPAKLLNEVEGLE
VVELPKYYNCCGFGGTFAVKMSDVSGEMVDEKVDCIVESGADYLVGGDCSCLMNIDGRLRRRGVDVKAVHIIEILNNQVE
AVTTR

Specific function: Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source

COG id: COG0247

COG function: function code C; Fe-S oxidoreductase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the lutA/ykgE family

Homologues:

Organism=Escherichia coli, GI1786497, Length=239, Percent_Identity=46.8619246861925, Blast_Score=233, Evalue=6e-63,
Organism=Escherichia coli, GI48994913, Length=248, Percent_Identity=22.9838709677419, Blast_Score=72, Evalue=4e-14,
Organism=Escherichia coli, GI1788576, Length=226, Percent_Identity=26.9911504424779, Blast_Score=63, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): LUTA_MACCJ (B9E9G8)

Other databases:

- EMBL:   AP009484
- RefSeq:   YP_002559575.1
- GeneID:   7390911
- GenomeReviews:   AP009484_GR
- KEGG:   mcl:MCCL_0172
- OMA:   GAYFPHR
- HAMAP:   MF_02105
- InterPro:   IPR004017
- InterPro:   IPR022822

Pfam domain/function: PF02754 CCG

EC number: NA

Molecular weight: Translated: 26767; Mature: 26767

Theoretical pI: Translated: 5.01; Mature: 5.01

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.5 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
7.3 %Cys+Met (Translated Protein)
4.5 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
7.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKVSLFSTCLVDVFEKRVGIATVELLEKLGCEVDFPAAQVCCGQPAYNSGYHEETKKAAK
CCCHHHHHHHHHHHHHHHCHHHHHHHHHHCCCCCCCHHHHHCCCCCCCCCCHHHHHHHHH
NMIKAFEQSEVVVAPSGSCVTMFKHYPDLFKNDAKWQARAQELADKTYEVTQFIVEVLGI
HHHHHHHCCCEEEECCCCEEHHHHHCHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
TNVGAKLDGVATIHPSCHMTRLLGNVTAPAKLLNEVEGLEVVELPKYYNCCGFGGTFAVK
CCCCCCCCCEEEECCCHHHHHHHHCCCHHHHHHHHHCCCEEEECCCHHCCCCCCCEEEEE
MSDVSGEMVDEKVDCIVESGADYLVGGDCSCLMNIDGRLRRRGVDVKAVHIIEILNNQVE
EECCCCHHHHHHHHHHHHCCCCEEECCCCEEEECCCHHHHHCCCCHHHHHHHHHHCCCHH
AVTTR
EEECC
>Mature Secondary Structure
MKVSLFSTCLVDVFEKRVGIATVELLEKLGCEVDFPAAQVCCGQPAYNSGYHEETKKAAK
CCCHHHHHHHHHHHHHHHCHHHHHHHHHHCCCCCCCHHHHHCCCCCCCCCCHHHHHHHHH
NMIKAFEQSEVVVAPSGSCVTMFKHYPDLFKNDAKWQARAQELADKTYEVTQFIVEVLGI
HHHHHHHCCCEEEECCCCEEHHHHHCHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
TNVGAKLDGVATIHPSCHMTRLLGNVTAPAKLLNEVEGLEVVELPKYYNCCGFGGTFAVK
CCCCCCCCCEEEECCCHHHHHHHHCCCHHHHHHHHHCCCEEEECCCHHCCCCCCCEEEEE
MSDVSGEMVDEKVDCIVESGADYLVGGDCSCLMNIDGRLRRRGVDVKAVHIIEILNNQVE
EECCCCHHHHHHHHHHHHCCCCEEECCCCEEEECCCHHHHHCCCCHHHHHHHHHHCCCHH
AVTTR
EEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA