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The map label for this gene is 221229644

Identifier: 221229644

GI number: 221229644

Start: 593303

End: 594970

Strand: Direct

Name: 221229644

Synonym: MLBr_00489

Alternate gene names: NA

Gene position: 593303-594970 (Clockwise)

Preceding gene: 221229643

Following gene: 221229645

Centisome position: 18.15

GC content: 62.23

Gene sequence:

>1668_bases
TTGCGGTCCGGCTTATTCGGGGTTTTGCGGTGGACTGCAGTAGGCTTGGTCGCGACGCTGGTGGCTTCTTTGGCGCTGAC
TGCGTGTTCTGGAAGCGCCGCGGGGGAGATCGTCTATGTGGTCGACGGGGCGTTGGGTACCTACAACACTAACACCATCG
TCGGTGCTGCGTCGGCCGGAGCGCAGGCGTTTGCCCGCACGCTCATCGGCTTCGGCTATCACGGCCCCGATGGACAGATA
GTCGCTGACCACGACTTCGGAACCATCACGGTGGTGGGCGGGGTGCCATTAGTGCTCGACTACCAGATAGCCGACAATGC
TGTCTACTCCGACGGCAAGCAGGTGACTTGCGATGATTTGGTGCTGACCTGGGCTGCCCAGTCTGGGCGGTTTCCCGGCT
TCGATGCTGCCACCCAGGCCGGTTACCGCGACATTGCTAATATCGAGTGCCTGGCCGGGCAGAAGAAATCCCGCGTGTTC
TTCGTCCCGGACCGCAGCGTTGTCGATTATGAACAGCTGTTCGCCGCGACCTCGATGATGCCGTCACACGTCATCGCTGA
CCAACTGAATATCGACGTGACGGAGGCATTGCTGACCCACAATGCGACATTGGTGGAACAGATCGCGCGATTGTGGAACA
CCACCTGGGACCTCAAACCAGCTGTCGATTTGAGACGCTTCCCGTCGTCAGGCCCATACAAGATCGAATCCGTCTTGAAC
GGTGGCGCTGTAGTGCTTGTAGCCAACGACCGTTGGTGGGGTCTCAAGGCGACCACCAAGCGGATCACAGTACGGCCACA
GGAAGCCGACATCCAGGACCGAGTCAACAACCGCAGCGTCGACGTCGTCGATGTCGCGGTCGGGTCGTCGGGATCGCTGG
CCACTCCGGACAATTACGCGCGCATCGACTCGCCGTCGGCGGGCATCGAGCAGCTGATCTTTGCGCCGCAGGGGCTGCTG
GCTGCGGCTGCCGCCCGCCGCGCACTCGCGCTGTGTACGCCACGCGACGTGGTCGCTCGAGACGCGGGGTTGTCGATCGC
CAACTCACGCCTGTCCCCGGCTACCGAGGATGCCATCGCTGCGGCCGACGGTGCTCGCGAGGCCGGCCAGTTCAGCAAGG
CGGATCCCGCCGCAGCGCACGACGCACTTAGTGGTGAGACGTTGCCGGTGCGGATCGGCTACCAAGGGCCCAACGCACGG
TTGGCGGCCACCGTCGGGACTATCGCCAAGGCGTGCGCTGTAGCTGGTATCAGTGTGTCCAGCGTTACCTTGGACTCCTC
GACGGACCCCTCGGGCCCGCAGGCGCTTCGGGACGGAAAGATCGACGTGCTGTTGGCCAGCACTGGTGGCGCCACCGGCA
GCGGATCGAGTGGGTCATCTTCGATGGATGCCTATGACCTACACACCGGCAACGGCAACAACCTGTCTGGCTATGCAAAC
GCGCAGGTTGACAACAATATCGGCGCGTTGGCGGTATCCGCTGACCCAGCCGAGCGTGTTCGGCTCCTCGCCGATAGTGC
ACCTGTACTCTGGGCGGATATGCCGACATTGCCTCTATACCGGCAGCAGCGAATGCTGCTGATGTCGAAGACAATGTATG
CAGTTACCAGGAATCCGACCCGTTGGGGCGCGGGTTGGAACATGGATCGATGGGCGTTAGTACGATGA

Upstream 100 bases:

>100_bases
GGCCGACCGGTACCCGACGTCCTACCGGCAAGCGAAACAACGTCGGTCGGCGGTAGTCAAGGTGGCTACCCGAGGTTGGC
AAGCCGTGAGTGAGTACGAT

Downstream 100 bases:

>100_bases
AAAGCTTTAAGGTTTGAGGAGGTGTCTCCGTGGCCGACCTTATCGCTGCCTTGACTCGGAATGCGGCCGATTTCCCGACG
CCAGCCATCCAGTTCAAGGA

Product: putative lipoprotein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 555; Mature: 555

Protein sequence:

>555_residues
MRSGLFGVLRWTAVGLVATLVASLALTACSGSAAGEIVYVVDGALGTYNTNTIVGAASAGAQAFARTLIGFGYHGPDGQI
VADHDFGTITVVGGVPLVLDYQIADNAVYSDGKQVTCDDLVLTWAAQSGRFPGFDAATQAGYRDIANIECLAGQKKSRVF
FVPDRSVVDYEQLFAATSMMPSHVIADQLNIDVTEALLTHNATLVEQIARLWNTTWDLKPAVDLRRFPSSGPYKIESVLN
GGAVVLVANDRWWGLKATTKRITVRPQEADIQDRVNNRSVDVVDVAVGSSGSLATPDNYARIDSPSAGIEQLIFAPQGLL
AAAAARRALALCTPRDVVARDAGLSIANSRLSPATEDAIAAADGAREAGQFSKADPAAAHDALSGETLPVRIGYQGPNAR
LAATVGTIAKACAVAGISVSSVTLDSSTDPSGPQALRDGKIDVLLASTGGATGSGSSGSSSMDAYDLHTGNGNNLSGYAN
AQVDNNIGALAVSADPAERVRLLADSAPVLWADMPTLPLYRQQRMLLMSKTMYAVTRNPTRWGAGWNMDRWALVR

Sequences:

>Translated_555_residues
MRSGLFGVLRWTAVGLVATLVASLALTACSGSAAGEIVYVVDGALGTYNTNTIVGAASAGAQAFARTLIGFGYHGPDGQI
VADHDFGTITVVGGVPLVLDYQIADNAVYSDGKQVTCDDLVLTWAAQSGRFPGFDAATQAGYRDIANIECLAGQKKSRVF
FVPDRSVVDYEQLFAATSMMPSHVIADQLNIDVTEALLTHNATLVEQIARLWNTTWDLKPAVDLRRFPSSGPYKIESVLN
GGAVVLVANDRWWGLKATTKRITVRPQEADIQDRVNNRSVDVVDVAVGSSGSLATPDNYARIDSPSAGIEQLIFAPQGLL
AAAAARRALALCTPRDVVARDAGLSIANSRLSPATEDAIAAADGAREAGQFSKADPAAAHDALSGETLPVRIGYQGPNAR
LAATVGTIAKACAVAGISVSSVTLDSSTDPSGPQALRDGKIDVLLASTGGATGSGSSGSSSMDAYDLHTGNGNNLSGYAN
AQVDNNIGALAVSADPAERVRLLADSAPVLWADMPTLPLYRQQRMLLMSKTMYAVTRNPTRWGAGWNMDRWALVR
>Mature_555_residues
MRSGLFGVLRWTAVGLVATLVASLALTACSGSAAGEIVYVVDGALGTYNTNTIVGAASAGAQAFARTLIGFGYHGPDGQI
VADHDFGTITVVGGVPLVLDYQIADNAVYSDGKQVTCDDLVLTWAAQSGRFPGFDAATQAGYRDIANIECLAGQKKSRVF
FVPDRSVVDYEQLFAATSMMPSHVIADQLNIDVTEALLTHNATLVEQIARLWNTTWDLKPAVDLRRFPSSGPYKIESVLN
GGAVVLVANDRWWGLKATTKRITVRPQEADIQDRVNNRSVDVVDVAVGSSGSLATPDNYARIDSPSAGIEQLIFAPQGLL
AAAAARRALALCTPRDVVARDAGLSIANSRLSPATEDAIAAADGAREAGQFSKADPAAAHDALSGETLPVRIGYQGPNAR
LAATVGTIAKACAVAGISVSSVTLDSSTDPSGPQALRDGKIDVLLASTGGATGSGSSGSSSMDAYDLHTGNGNNLSGYAN
AQVDNNIGALAVSADPAERVRLLADSAPVLWADMPTLPLYRQQRMLLMSKTMYAVTRNPTRWGAGWNMDRWALVR

Specific function: Unknown

COG id: COG0747

COG function: function code E; ABC-type dipeptide transport system, periplasmic component

Gene ontology:

Cell location: Cell membrane; Lipid-anchor (Probable)

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: To M.tuberculosis Rv2585c and M.bovis Mb2616c

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): Y489_MYCLE (Q49646)

Other databases:

- EMBL:   U00011
- EMBL:   AL023591
- EMBL:   AL583918
- PIR:   A86970
- PIR:   S72732
- RefSeq:   NP_301429.1
- ProteinModelPortal:   Q49646
- EnsemblBacteria:   EBMYCT00000028514
- GeneID:   909242
- GenomeReviews:   AL450380_GR
- KEGG:   mle:ML0489
- NMPDR:   fig|272631.1.peg.301
- Leproma:   ML0489
- GeneTree:   EBGT00050000016139
- HOGENOM:   HBG564678
- OMA:   WNMDRWV
- ProtClustDB:   CLSK791940
- BioCyc:   MLEP272631:ML0489-MONOMER
- InterPro:   IPR000914

Pfam domain/function: PF00496 SBP_bac_5

EC number: NA

Molecular weight: Translated: 58109; Mature: 58109

Theoretical pI: Translated: 5.14; Mature: 5.14

Prosite motif: PS51257 PROKAR_LIPOPROTEIN; PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRSGLFGVLRWTAVGLVATLVASLALTACSGSAAGEIVYVVDGALGTYNTNTIVGAASAG
CCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCCCCEEEEECCCC
AQAFARTLIGFGYHGPDGQIVADHDFGTITVVGGVPLVLDYQIADNAVYSDGKQVTCDDL
HHHHHHHHHHCCEECCCCCEEEECCCCEEEEECCCEEEEEEEECCCCEECCCCEEEHHHE
VLTWAAQSGRFPGFDAATQAGYRDIANIECLAGQKKSRVFFVPDRSVVDYEQLFAATSMM
EEEEECCCCCCCCCCHHHHCCCHHCCCEEEECCCCCCEEEECCCCCCCCHHHHHHHHHCC
PSHVIADQLNIDVTEALLTHNATLVEQIARLWNTTWDLKPAVDLRRFPSSGPYKIESVLN
CHHHHHHHCCCHHHHHHHHCCHHHHHHHHHHHCCCCCCCCCHHHHCCCCCCCEEEHEECC
GGAVVLVANDRWWGLKATTKRITVRPQEADIQDRVNNRSVDVVDVAVGSSGSLATPDNYA
CCEEEEEECCCEECEEECCEEEEECCCCCCHHHHCCCCCEEEEEEEECCCCCCCCCCCCC
RIDSPSAGIEQLIFAPQGLLAAAAARRALALCTPRDVVARDAGLSIANSRLSPATEDAIA
CCCCCCCCHHHHHHCCCHHHHHHHHHHHEEECCCHHHHHHCCCCEECCCCCCCCCHHHHH
AADGAREAGQFSKADPAAAHDALSGETLPVRIGYQGPNARLAATVGTIAKACAVAGISVS
HCCCCHHHCCCCCCCCCHHHHCCCCCEEEEEEECCCCCCEEEHHHHHHHHHHHHCCCEEE
SVTLDSSTDPSGPQALRDGKIDVLLASTGGATGSGSSGSSSMDAYDLHTGNGNNLSGYAN
EEEECCCCCCCCCHHHHCCCEEEEEEECCCCCCCCCCCCCCCCEEEEECCCCCCCCCEEE
AQVDNNIGALAVSADPAERVRLLADSAPVLWADMPTLPLYRQQRMLLMSKTMYAVTRNPT
CEECCCCEEEEEECCHHHHHHHHHCCCCEEEECCCCCCHHHHHHHHHHHHHEEEEECCCC
RWGAGWNMDRWALVR
CCCCCCCCCCEEECC
>Mature Secondary Structure
MRSGLFGVLRWTAVGLVATLVASLALTACSGSAAGEIVYVVDGALGTYNTNTIVGAASAG
CCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCCCCEEEEECCCC
AQAFARTLIGFGYHGPDGQIVADHDFGTITVVGGVPLVLDYQIADNAVYSDGKQVTCDDL
HHHHHHHHHHCCEECCCCCEEEECCCCEEEEECCCEEEEEEEECCCCEECCCCEEEHHHE
VLTWAAQSGRFPGFDAATQAGYRDIANIECLAGQKKSRVFFVPDRSVVDYEQLFAATSMM
EEEEECCCCCCCCCCHHHHCCCHHCCCEEEECCCCCCEEEECCCCCCCCHHHHHHHHHCC
PSHVIADQLNIDVTEALLTHNATLVEQIARLWNTTWDLKPAVDLRRFPSSGPYKIESVLN
CHHHHHHHCCCHHHHHHHHCCHHHHHHHHHHHCCCCCCCCCHHHHCCCCCCCEEEHEECC
GGAVVLVANDRWWGLKATTKRITVRPQEADIQDRVNNRSVDVVDVAVGSSGSLATPDNYA
CCEEEEEECCCEECEEECCEEEEECCCCCCHHHHCCCCCEEEEEEEECCCCCCCCCCCCC
RIDSPSAGIEQLIFAPQGLLAAAAARRALALCTPRDVVARDAGLSIANSRLSPATEDAIA
CCCCCCCCHHHHHHCCCHHHHHHHHHHHEEECCCHHHHHHCCCCEECCCCCCCCCHHHHH
AADGAREAGQFSKADPAAAHDALSGETLPVRIGYQGPNARLAATVGTIAKACAVAGISVS
HCCCCHHHCCCCCCCCCHHHHCCCCCEEEEEEECCCCCCEEEHHHHHHHHHHHHCCCEEE
SVTLDSSTDPSGPQALRDGKIDVLLASTGGATGSGSSGSSSMDAYDLHTGNGNNLSGYAN
EEEECCCCCCCCCHHHHCCCEEEEEEECCCCCCCCCCCCCCCCEEEEECCCCCCCCCEEE
AQVDNNIGALAVSADPAERVRLLADSAPVLWADMPTLPLYRQQRMLLMSKTMYAVTRNPT
CEECCCCEEEEEECCHHHHHHHHHCCCCEEEECCCCCCHHHHHHHHHHHHHEEEEECCCC
RWGAGWNMDRWALVR
CCCCCCCCCCEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11234002