| Definition | Escherichia fergusonii ATCC 35469 chromosome, complete genome. |
|---|---|
| Accession | NC_011740 |
| Length | 4,588,711 |
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The map label for this gene is rbtD [H]
Identifier: 218549508
GI number: 218549508
Start: 2219512
End: 2220264
Strand: Direct
Name: rbtD [H]
Synonym: EFER_2179
Alternate gene names: 218549508
Gene position: 2219512-2220264 (Clockwise)
Preceding gene: 218549506
Following gene: 218549509
Centisome position: 48.37
GC content: 51.39
Gene sequence:
>753_bases ATGATGAATCACTCTGTGCCCTCTATGAATACTCCCCTTAATGGCAAAGTTGCGGCTATCACTGGCGCTGCGTCAGGTAT TGGCCTGCAGTGTGCAAAAACGCTGCTTGATGCAGGAGCAAAGGTAGTATTGATTGACCGGGAAGGCGACAAACTGCAAA AGATTGTCGCTGAGTTAGGTGAAAACGCGTACGCGCTGCAACTCGATCTCTTCAATAATCAGCAAGTCGATAACATGTTG GCGGGCATTATCGAACTGGCGGGTGGGCTGGATATTTTTCATGCCAATGCAGGGGCTTACATTGGCGGCCCGGTGGCTGA AGGTGATCCAGACGTCTGGGATCGCGTATTAAATCTGAATATAAATGCGGCGTTTCGCTGTGTCCGTGCTGTCCTGCCAC ATATGATTGCGCAGAAATCGGGCGATATTATTTTTACCAGTTCCATCGCGGGCGTCGTTCCGGTTATCTGGGAACCGATC TACACCGCGTCCAAATTTGCCGTTCAGGCGTTCGTACACACTACCCGCCGCCAGGTTTCTCAATATGGCGTACGTGTGGG TGCGGTACTGCCAGGGCCGGTAGTCACTGCCCTGCTCGATGACTGGCCAAAAGCCAAAATGGAAGAAGCCCTGGCAAATG GTAGCCTGATGCAACCGATTGAAGTGGCGGAATCAGTACTATTTATGGTGACACGCTCGAAAAATGTCACCGTGCGAGAT TTAGTGATCCTGCCTGGCAGTGTCGATCTGTAA
Upstream 100 bases:
>100_bases GCTTCATCGATTGAGCAGTTTGCTTCACACGCCAGCTAAATTCCCGTTCAGTGCGTGCCAGCAAACAGAGACTATAAATT CGCCCTGGTAAAAGGATTAT
Downstream 100 bases:
>100_bases GGGCGCAATCATGACAATAACCAAAACCGTTATTGGTGTTGATGTGGGATCAGGCAGTGTCCGCGCCGGGATTTTTGATC TCAACGGATCTCTGCTATCC
Product: Ribitol 2-dehydrogenase
Products: NA
Alternate protein names: RDH [H]
Number of amino acids: Translated: 250; Mature: 250
Protein sequence:
>250_residues MMNHSVPSMNTPLNGKVAAITGAASGIGLQCAKTLLDAGAKVVLIDREGDKLQKIVAELGENAYALQLDLFNNQQVDNML AGIIELAGGLDIFHANAGAYIGGPVAEGDPDVWDRVLNLNINAAFRCVRAVLPHMIAQKSGDIIFTSSIAGVVPVIWEPI YTASKFAVQAFVHTTRRQVSQYGVRVGAVLPGPVVTALLDDWPKAKMEEALANGSLMQPIEVAESVLFMVTRSKNVTVRD LVILPGSVDL
Sequences:
>Translated_250_residues MMNHSVPSMNTPLNGKVAAITGAASGIGLQCAKTLLDAGAKVVLIDREGDKLQKIVAELGENAYALQLDLFNNQQVDNML AGIIELAGGLDIFHANAGAYIGGPVAEGDPDVWDRVLNLNINAAFRCVRAVLPHMIAQKSGDIIFTSSIAGVVPVIWEPI YTASKFAVQAFVHTTRRQVSQYGVRVGAVLPGPVVTALLDDWPKAKMEEALANGSLMQPIEVAESVLFMVTRSKNVTVRD LVILPGSVDL >Mature_250_residues MMNHSVPSMNTPLNGKVAAITGAASGIGLQCAKTLLDAGAKVVLIDREGDKLQKIVAELGENAYALQLDLFNNQQVDNML AGIIELAGGLDIFHANAGAYIGGPVAEGDPDVWDRVLNLNINAAFRCVRAVLPHMIAQKSGDIIFTSSIAGVVPVIWEPI YTASKFAVQAFVHTTRRQVSQYGVRVGAVLPGPVVTALLDDWPKAKMEEALANGSLMQPIEVAESVLFMVTRSKNVTVRD LVILPGSVDL
Specific function: Unknown
COG id: COG4221
COG function: function code R; Short-chain alcohol dehydrogenase of unknown specificity
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]
Homologues:
Organism=Homo sapiens, GI20149619, Length=246, Percent_Identity=33.3333333333333, Blast_Score=115, Evalue=3e-26, Organism=Homo sapiens, GI31542939, Length=204, Percent_Identity=32.843137254902, Blast_Score=92, Evalue=5e-19, Organism=Homo sapiens, GI32483357, Length=254, Percent_Identity=26.7716535433071, Blast_Score=90, Evalue=2e-18, Organism=Homo sapiens, GI7657478, Length=188, Percent_Identity=33.5106382978723, Blast_Score=88, Evalue=8e-18, Organism=Homo sapiens, GI109715829, Length=244, Percent_Identity=27.0491803278689, Blast_Score=87, Evalue=1e-17, Organism=Homo sapiens, GI7706318, Length=197, Percent_Identity=29.4416243654822, Blast_Score=86, Evalue=3e-17, Organism=Homo sapiens, GI157739938, Length=243, Percent_Identity=26.3374485596708, Blast_Score=86, Evalue=3e-17, Organism=Homo sapiens, GI66933014, Length=195, Percent_Identity=34.3589743589744, Blast_Score=80, Evalue=3e-15, Organism=Homo sapiens, GI33667109, Length=189, Percent_Identity=28.042328042328, Blast_Score=79, Evalue=3e-15, Organism=Homo sapiens, GI7705855, Length=192, Percent_Identity=32.8125, Blast_Score=79, Evalue=4e-15, Organism=Homo sapiens, GI224922801, Length=170, Percent_Identity=32.9411764705882, Blast_Score=79, Evalue=4e-15, Organism=Homo sapiens, GI5031737, Length=189, Percent_Identity=28.042328042328, Blast_Score=79, Evalue=4e-15, Organism=Homo sapiens, GI40254992, Length=215, Percent_Identity=24.6511627906977, Blast_Score=76, Evalue=3e-14, Organism=Homo sapiens, GI142976729, Length=250, Percent_Identity=25.2, Blast_Score=72, Evalue=3e-13, Organism=Homo sapiens, GI126723191, Length=192, Percent_Identity=27.6041666666667, Blast_Score=71, Evalue=9e-13, Organism=Homo sapiens, GI4503817, Length=226, Percent_Identity=25.6637168141593, Blast_Score=70, Evalue=1e-12, Organism=Homo sapiens, GI223718074, Length=194, Percent_Identity=29.3814432989691, Blast_Score=70, Evalue=2e-12, Organism=Homo sapiens, GI15277342, Length=238, Percent_Identity=26.890756302521, Blast_Score=70, Evalue=2e-12, Organism=Homo sapiens, GI32455239, Length=182, Percent_Identity=31.3186813186813, Blast_Score=69, Evalue=6e-12, Organism=Homo sapiens, GI5031765, Length=182, Percent_Identity=31.3186813186813, Blast_Score=69, Evalue=6e-12, Organism=Homo sapiens, GI19923817, Length=239, Percent_Identity=23.8493723849372, Blast_Score=67, Evalue=1e-11, Organism=Homo sapiens, GI210032110, Length=252, Percent_Identity=24.6031746031746, Blast_Score=66, Evalue=4e-11, Organism=Homo sapiens, GI22507405, Length=196, Percent_Identity=31.1224489795918, Blast_Score=65, Evalue=4e-11, Organism=Homo sapiens, GI59889578, Length=228, Percent_Identity=24.5614035087719, Blast_Score=65, Evalue=4e-11, Organism=Homo sapiens, GI126723750, Length=247, Percent_Identity=23.8866396761134, Blast_Score=65, Evalue=8e-11, Organism=Escherichia coli, GI1787820, Length=234, Percent_Identity=30.3418803418803, Blast_Score=100, Evalue=1e-22, Organism=Escherichia coli, GI87082100, Length=233, Percent_Identity=30.4721030042918, Blast_Score=90, Evalue=1e-19, Organism=Escherichia coli, GI1787335, Length=222, Percent_Identity=28.8288288288288, Blast_Score=89, Evalue=2e-19, Organism=Escherichia coli, GI87082160, Length=200, Percent_Identity=28, Blast_Score=79, Evalue=3e-16, Organism=Escherichia coli, GI1787526, Length=206, Percent_Identity=32.0388349514563, Blast_Score=79, Evalue=4e-16, Organism=Escherichia coli, GI1788459, Length=240, Percent_Identity=27.9166666666667, Blast_Score=78, Evalue=5e-16, Organism=Escherichia coli, GI1787905, Length=232, Percent_Identity=30.6034482758621, Blast_Score=77, Evalue=1e-15, Organism=Escherichia coli, GI1786701, Length=207, Percent_Identity=28.0193236714976, Blast_Score=75, Evalue=3e-15, Organism=Escherichia coli, GI1789208, Length=187, Percent_Identity=31.5508021390374, Blast_Score=72, Evalue=4e-14, Organism=Escherichia coli, GI1789378, Length=242, Percent_Identity=26.0330578512397, Blast_Score=71, Evalue=7e-14, Organism=Escherichia coli, GI1786812, Length=251, Percent_Identity=25.0996015936255, Blast_Score=69, Evalue=3e-13, Organism=Escherichia coli, GI1790717, Length=196, Percent_Identity=28.0612244897959, Blast_Score=69, Evalue=4e-13, Organism=Caenorhabditis elegans, GI193204405, Length=244, Percent_Identity=29.9180327868852, Blast_Score=96, Evalue=2e-20, Organism=Caenorhabditis elegans, GI71994600, Length=246, Percent_Identity=30.0813008130081, Blast_Score=93, Evalue=1e-19, Organism=Caenorhabditis elegans, GI17562910, Length=246, Percent_Identity=29.2682926829268, Blast_Score=91, Evalue=4e-19, Organism=Caenorhabditis elegans, GI17562906, Length=246, Percent_Identity=29.2682926829268, Blast_Score=91, Evalue=5e-19, Organism=Caenorhabditis elegans, GI71994604, Length=245, Percent_Identity=28.5714285714286, Blast_Score=90, Evalue=1e-18, Organism=Caenorhabditis elegans, GI17562908, Length=247, Percent_Identity=28.3400809716599, Blast_Score=89, Evalue=2e-18, Organism=Caenorhabditis elegans, GI17560676, Length=229, Percent_Identity=28.3842794759825, Blast_Score=89, Evalue=3e-18, Organism=Caenorhabditis elegans, GI17544670, Length=264, Percent_Identity=31.0606060606061, Blast_Score=89, Evalue=3e-18, Organism=Caenorhabditis elegans, GI17559104, Length=259, Percent_Identity=28.5714285714286, Blast_Score=87, Evalue=7e-18, Organism=Caenorhabditis elegans, GI17531453, Length=243, Percent_Identity=29.2181069958848, Blast_Score=86, Evalue=2e-17, Organism=Caenorhabditis elegans, GI17560220, Length=246, Percent_Identity=27.6422764227642, Blast_Score=81, Evalue=4e-16, Organism=Caenorhabditis elegans, GI17560332, Length=262, Percent_Identity=27.0992366412214, Blast_Score=80, Evalue=1e-15, Organism=Caenorhabditis elegans, GI17560150, Length=242, Percent_Identity=26.8595041322314, Blast_Score=78, Evalue=4e-15, Organism=Caenorhabditis elegans, GI17538480, Length=248, Percent_Identity=26.2096774193548, Blast_Score=75, Evalue=3e-14, Organism=Caenorhabditis elegans, GI17562990, Length=241, Percent_Identity=26.1410788381743, Blast_Score=74, Evalue=5e-14, Organism=Caenorhabditis elegans, GI72000259, Length=244, Percent_Identity=25, Blast_Score=74, Evalue=5e-14, Organism=Caenorhabditis elegans, GI17562904, Length=244, Percent_Identity=25.4098360655738, Blast_Score=74, Evalue=6e-14, Organism=Caenorhabditis elegans, GI17561402, Length=258, Percent_Identity=24.4186046511628, Blast_Score=74, Evalue=8e-14, Organism=Caenorhabditis elegans, GI25147288, Length=230, Percent_Identity=26.9565217391304, Blast_Score=74, Evalue=9e-14, Organism=Caenorhabditis elegans, GI17555706, Length=232, Percent_Identity=25, Blast_Score=73, Evalue=2e-13, Organism=Caenorhabditis elegans, GI17563726, Length=246, Percent_Identity=26.0162601626016, Blast_Score=70, Evalue=9e-13, Organism=Caenorhabditis elegans, GI17551412, Length=254, Percent_Identity=25.5905511811024, Blast_Score=66, Evalue=2e-11, Organism=Caenorhabditis elegans, GI17538486, Length=243, Percent_Identity=25.9259259259259, Blast_Score=65, Evalue=3e-11, Organism=Caenorhabditis elegans, GI17568967, Length=192, Percent_Identity=27.0833333333333, Blast_Score=65, Evalue=5e-11, Organism=Caenorhabditis elegans, GI17555612, Length=236, Percent_Identity=27.9661016949153, Blast_Score=64, Evalue=5e-11, Organism=Caenorhabditis elegans, GI17564282, Length=193, Percent_Identity=25.9067357512953, Blast_Score=64, Evalue=9e-11, Organism=Saccharomyces cerevisiae, GI6323882, Length=249, Percent_Identity=29.718875502008, Blast_Score=87, Evalue=2e-18, Organism=Saccharomyces cerevisiae, GI6322067, Length=192, Percent_Identity=26.5625, Blast_Score=71, Evalue=2e-13, Organism=Saccharomyces cerevisiae, GI6322227, Length=196, Percent_Identity=29.5918367346939, Blast_Score=69, Evalue=6e-13, Organism=Drosophila melanogaster, GI21358495, Length=243, Percent_Identity=30.4526748971193, Blast_Score=96, Evalue=3e-20, Organism=Drosophila melanogaster, GI28571387, Length=241, Percent_Identity=29.4605809128631, Blast_Score=95, Evalue=4e-20, Organism=Drosophila melanogaster, GI24639444, Length=226, Percent_Identity=31.4159292035398, Blast_Score=94, Evalue=6e-20, Organism=Drosophila melanogaster, GI21355319, Length=233, Percent_Identity=29.6137339055794, Blast_Score=92, Evalue=4e-19, Organism=Drosophila melanogaster, GI24641232, Length=246, Percent_Identity=29.6747967479675, Blast_Score=87, Evalue=1e-17, Organism=Drosophila melanogaster, GI23397609, Length=244, Percent_Identity=29.9180327868852, Blast_Score=86, Evalue=2e-17, Organism=Drosophila melanogaster, GI28571526, Length=235, Percent_Identity=28.936170212766, Blast_Score=86, Evalue=3e-17, Organism=Drosophila melanogaster, GI21357041, Length=219, Percent_Identity=30.5936073059361, Blast_Score=85, Evalue=4e-17, Organism=Drosophila melanogaster, GI24663911, Length=244, Percent_Identity=28.2786885245902, Blast_Score=85, Evalue=4e-17, Organism=Drosophila melanogaster, GI24643142, Length=220, Percent_Identity=33.1818181818182, Blast_Score=82, Evalue=5e-16, Organism=Drosophila melanogaster, GI24641388, Length=254, Percent_Identity=28.740157480315, Blast_Score=81, Evalue=5e-16, Organism=Drosophila melanogaster, GI24648944, Length=239, Percent_Identity=28.0334728033473, Blast_Score=79, Evalue=3e-15, Organism=Drosophila melanogaster, GI116007236, Length=246, Percent_Identity=26.4227642276423, Blast_Score=79, Evalue=3e-15, Organism=Drosophila melanogaster, GI281364892, Length=231, Percent_Identity=27.7056277056277, Blast_Score=78, Evalue=4e-15, Organism=Drosophila melanogaster, GI24580925, Length=202, Percent_Identity=28.2178217821782, Blast_Score=78, Evalue=6e-15, Organism=Drosophila melanogaster, GI24644339, Length=230, Percent_Identity=29.1304347826087, Blast_Score=78, Evalue=7e-15, Organism=Drosophila melanogaster, GI24640442, Length=193, Percent_Identity=30.0518134715026, Blast_Score=77, Evalue=8e-15, Organism=Drosophila melanogaster, GI281364494, Length=246, Percent_Identity=26.4227642276423, Blast_Score=77, Evalue=1e-14, Organism=Drosophila melanogaster, GI21355631, Length=171, Percent_Identity=28.0701754385965, Blast_Score=74, Evalue=7e-14, Organism=Drosophila melanogaster, GI24665243, Length=199, Percent_Identity=29.1457286432161, Blast_Score=74, Evalue=1e-13, Organism=Drosophila melanogaster, GI221331218, Length=201, Percent_Identity=28.8557213930348, Blast_Score=74, Evalue=1e-13, Organism=Drosophila melanogaster, GI24665247, Length=200, Percent_Identity=29.5, Blast_Score=72, Evalue=4e-13, Organism=Drosophila melanogaster, GI221331216, Length=202, Percent_Identity=29.2079207920792, Blast_Score=72, Evalue=5e-13, Organism=Drosophila melanogaster, GI24648693, Length=253, Percent_Identity=26.8774703557312, Blast_Score=71, Evalue=6e-13, Organism=Drosophila melanogaster, GI21355889, Length=253, Percent_Identity=26.8774703557312, Blast_Score=71, Evalue=6e-13, Organism=Drosophila melanogaster, GI116007238, Length=196, Percent_Identity=26.0204081632653, Blast_Score=70, Evalue=2e-12, Organism=Drosophila melanogaster, GI21356301, Length=224, Percent_Identity=26.7857142857143, Blast_Score=67, Evalue=1e-11, Organism=Drosophila melanogaster, GI17737361, Length=201, Percent_Identity=28.3582089552239, Blast_Score=67, Evalue=1e-11, Organism=Drosophila melanogaster, GI116007234, Length=245, Percent_Identity=25.7142857142857, Blast_Score=66, Evalue=2e-11, Organism=Drosophila melanogaster, GI28574402, Length=192, Percent_Identity=28.6458333333333, Blast_Score=66, Evalue=2e-11, Organism=Drosophila melanogaster, GI24584744, Length=192, Percent_Identity=28.6458333333333, Blast_Score=66, Evalue=2e-11, Organism=Drosophila melanogaster, GI18859837, Length=190, Percent_Identity=26.8421052631579, Blast_Score=65, Evalue=4e-11, Organism=Drosophila melanogaster, GI24649181, Length=185, Percent_Identity=25.4054054054054, Blast_Score=65, Evalue=6e-11,
Paralogues:
None
Copy number: 1300 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). [C]
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR002198 - InterPro: IPR002347 - InterPro: IPR016040 - InterPro: IPR020904 [H]
Pfam domain/function: PF00106 adh_short [H]
EC number: =1.1.1.56 [H]
Molecular weight: Translated: 26598; Mature: 26598
Theoretical pI: Translated: 5.27; Mature: 5.27
Prosite motif: PS00061 ADH_SHORT
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.8 %Cys (Translated Protein) 3.2 %Met (Translated Protein) 4.0 %Cys+Met (Translated Protein) 0.8 %Cys (Mature Protein) 3.2 %Met (Mature Protein) 4.0 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MMNHSVPSMNTPLNGKVAAITGAASGIGLQCAKTLLDAGAKVVLIDREGDKLQKIVAELG CCCCCCCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHC ENAYALQLDLFNNQQVDNMLAGIIELAGGLDIFHANAGAYIGGPVAEGDPDVWDRVLNLN CCEEEEEEEECCCCCHHHHHHHHHHHHCCCEEEECCCCCEECCCCCCCCHHHHHHHHCCC INAAFRCVRAVLPHMIAQKSGDIIFTSSIAGVVPVIWEPIYTASKFAVQAFVHTTRRQVS HHHHHHHHHHHHHHHHHHCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH QYGVRVGAVLPGPVVTALLDDWPKAKMEEALANGSLMQPIEVAESVLFMVTRSKNVTVRD HHCEEEECCCCHHHHHHHHHCCCHHHHHHHHHCCCCCCHHHHHHHHHHHEECCCCCEEEE LVILPGSVDL EEEECCCCCC >Mature Secondary Structure MMNHSVPSMNTPLNGKVAAITGAASGIGLQCAKTLLDAGAKVVLIDREGDKLQKIVAELG CCCCCCCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHC ENAYALQLDLFNNQQVDNMLAGIIELAGGLDIFHANAGAYIGGPVAEGDPDVWDRVLNLN CCEEEEEEEECCCCCHHHHHHHHHHHHCCCEEEECCCCCEECCCCCCCCHHHHHHHHCCC INAAFRCVRAVLPHMIAQKSGDIIFTSSIAGVVPVIWEPIYTASKFAVQAFVHTTRRQVS HHHHHHHHHHHHHHHHHHCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH QYGVRVGAVLPGPVVTALLDDWPKAKMEEALANGSLMQPIEVAESVLFMVTRSKNVTVRD HHCEEEECCCCHHHHHHHHHCCCHHHHHHHHHCCCCCCHHHHHHHHHHHEECCCCCEEEE LVILPGSVDL EEEECCCCCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 10.0
TargetDB status: NA
Availability: NA
References: 3904726; 2933028; 3891331 [H]