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The map label for this gene is lsrR [H]

Identifier: 218549506

GI number: 218549506

Start: 2217378

End: 2218319

Strand: Direct

Name: lsrR [H]

Synonym: EFER_2177

Alternate gene names: 218549506

Gene position: 2217378-2218319 (Clockwise)

Preceding gene: 218549501

Following gene: 218549508

Centisome position: 48.32

GC content: 48.94

Gene sequence:

>942_bases
GTGAACAAAGAAGATGACATCAGGCTCGATCAAAAAGTACGGGCGGCATGGATGTACTACATTGCCGGGCTTAATCAGAG
CGAAATCGCCAGCCAGTTAGGCACTTCGCGGCCAGTGGTTCAACGCCTGATAGCGGCAGCAAAAGACGAAGGGATTGTGT
CAATTGGATTGCACCATCCGGTTGCCAACTGTCTCGATTATGCCCAACTGTTAAAGGAAAAGTACCAATTAACCGACTGC
AATATTGTGCCGGTGTACAGTATTGAAAGTACGCTCGATAGCGTGACATTTGGCTGTTATCAACTGATGGCGCGTTACTT
ACAGGGTGACAAACCGACCATCGTTGGTATTGGTTCTGGCTTAACGTTGAAGAAAACCATTAAACGTATTGATTTTGATA
GTCAGAATACCCGCTGTGTGGCGTTGATTAGCGCCATGAATGAACACGGGCAATGCAACTATTACGACGACGTACCGCTG
CTTTTGGCGAGAAAAATTCAGGGGAAATATTACCAGTGGCCTGCACCACGCTATGCTCAGTCGCGCGAAGAGTACCAAAT
GTGGTCAACCAACCGATTGTTCCGCAATGTCTCAACCGTGGCACGTGACTCTGATGTTATTTTCGTGGGTATCGGTGCTT
TAGGTCGTCAAAGCCCTATCTTCAAAGATGGTTTTATTGATGAGCAGCAACTGGAGGAGTTAACAGCACGCGGAGGCGTT
GGTGAAATCCTCGGACGCTTTATTGATGCTGAAGGCAATGTTGTGGAAAGCCAGATCAACCAGATGATCACCAGCCATGA
TATCCGCGAAAGCAACTGCCCACGTATCGCTGCTGCCTGTGGTGAGGATAAACGTCCGGCGATCCTCGCGGCATTAAAAG
GTGGGTGGATCAACGGTCTGGTTACCGATGAACACACCGCACGCTGGTTGCTGACACGTTAA

Upstream 100 bases:

>100_bases
AAAGCAATAAACTTGCCTCGCGGTAAAGCTATCGCCAAAATGACGCTAATCTGTTGCGGGATTTTCACGATTCCGCACGC
CACTTTTGAGGTAGGGAAAC

Downstream 100 bases:

>100_bases
TCTCAGCTGACAACATTCAGGCTGGGAATGAGTTGTGGCGGTATCTCAATGCGACGCAGGGTGGTATCGCCAGAATCCAC
AATTTCAAACACTTTTTCGA

Product: D-arabitol repressor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 313; Mature: 313

Protein sequence:

>313_residues
MNKEDDIRLDQKVRAAWMYYIAGLNQSEIASQLGTSRPVVQRLIAAAKDEGIVSIGLHHPVANCLDYAQLLKEKYQLTDC
NIVPVYSIESTLDSVTFGCYQLMARYLQGDKPTIVGIGSGLTLKKTIKRIDFDSQNTRCVALISAMNEHGQCNYYDDVPL
LLARKIQGKYYQWPAPRYAQSREEYQMWSTNRLFRNVSTVARDSDVIFVGIGALGRQSPIFKDGFIDEQQLEELTARGGV
GEILGRFIDAEGNVVESQINQMITSHDIRESNCPRIAAACGEDKRPAILAALKGGWINGLVTDEHTARWLLTR

Sequences:

>Translated_313_residues
MNKEDDIRLDQKVRAAWMYYIAGLNQSEIASQLGTSRPVVQRLIAAAKDEGIVSIGLHHPVANCLDYAQLLKEKYQLTDC
NIVPVYSIESTLDSVTFGCYQLMARYLQGDKPTIVGIGSGLTLKKTIKRIDFDSQNTRCVALISAMNEHGQCNYYDDVPL
LLARKIQGKYYQWPAPRYAQSREEYQMWSTNRLFRNVSTVARDSDVIFVGIGALGRQSPIFKDGFIDEQQLEELTARGGV
GEILGRFIDAEGNVVESQINQMITSHDIRESNCPRIAAACGEDKRPAILAALKGGWINGLVTDEHTARWLLTR
>Mature_313_residues
MNKEDDIRLDQKVRAAWMYYIAGLNQSEIASQLGTSRPVVQRLIAAAKDEGIVSIGLHHPVANCLDYAQLLKEKYQLTDC
NIVPVYSIESTLDSVTFGCYQLMARYLQGDKPTIVGIGSGLTLKKTIKRIDFDSQNTRCVALISAMNEHGQCNYYDDVPL
LLARKIQGKYYQWPAPRYAQSREEYQMWSTNRLFRNVSTVARDSDVIFVGIGALGRQSPIFKDGFIDEQQLEELTARGGV
GEILGRFIDAEGNVVESQINQMITSHDIRESNCPRIAAACGEDKRPAILAALKGGWINGLVTDEHTARWLLTR

Specific function: Regulates transcription of many different genes. In the absence of autoinducer 2 (AI-2), represses transcription of the lsr operon and its own transcription. In the presence of AI-2, lsrR is inactivated by binding phospho-AI-2, leading to the transcriptio

COG id: COG2390

COG function: function code K; Transcriptional regulator, contains sigma factor-related N-terminal domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sorC transcriptional regulatory family [H]

Homologues:

Organism=Escherichia coli, GI1787791, Length=313, Percent_Identity=31.9488817891374, Blast_Score=135, Evalue=2e-33,
Organism=Escherichia coli, GI87082414, Length=311, Percent_Identity=25.7234726688103, Blast_Score=95, Evalue=7e-21,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007324
- InterPro:   IPR011991 [H]

Pfam domain/function: PF04198 Sugar-bind [H]

EC number: NA

Molecular weight: Translated: 35051; Mature: 35051

Theoretical pI: Translated: 6.66; Mature: 6.66

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKEDDIRLDQKVRAAWMYYIAGLNQSEIASQLGTSRPVVQRLIAAAKDEGIVSIGLHHP
CCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHCCCCHHHHHHHHHHCCCCEEEEECCCH
VANCLDYAQLLKEKYQLTDCNIVPVYSIESTLDSVTFGCYQLMARYLQGDKPTIVGIGSG
HHHHHHHHHHHHHHHCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCC
LTLKKTIKRIDFDSQNTRCVALISAMNEHGQCNYYDDVPLLLARKIQGKYYQWPAPRYAQ
CHHHHHHHHCCCCCCCCHHHHHHHHHCCCCCCCCCCCHHHHHHHHHCCCEEECCCCHHHH
SREEYQMWSTNRLFRNVSTVARDSDVIFVGIGALGRQSPIFKDGFIDEQQLEELTARGGV
CHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCCCCHHHHHHHHHCCCH
GEILGRFIDAEGNVVESQINQMITSHDIRESNCPRIAAACGEDKRPAILAALKGGWINGL
HHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCCCCHHHHCCCCCCCEEEEEECCCCEECE
VTDEHTARWLLTR
ECCCCCCCEEECC
>Mature Secondary Structure
MNKEDDIRLDQKVRAAWMYYIAGLNQSEIASQLGTSRPVVQRLIAAAKDEGIVSIGLHHP
CCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHCCCCHHHHHHHHHHCCCCEEEEECCCH
VANCLDYAQLLKEKYQLTDCNIVPVYSIESTLDSVTFGCYQLMARYLQGDKPTIVGIGSG
HHHHHHHHHHHHHHHCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCC
LTLKKTIKRIDFDSQNTRCVALISAMNEHGQCNYYDDVPLLLARKIQGKYYQWPAPRYAQ
CHHHHHHHHCCCCCCCCHHHHHHHHHCCCCCCCCCCCHHHHHHHHHCCCEEECCCCHHHH
SREEYQMWSTNRLFRNVSTVARDSDVIFVGIGALGRQSPIFKDGFIDEQQLEELTARGGV
CHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCCCCHHHHHHHHHCCCH
GEILGRFIDAEGNVVESQINQMITSHDIRESNCPRIAAACGEDKRPAILAALKGGWINGL
HHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCCCCHHHHCCCCCCCEEEEEECCCCEECE
VTDEHTARWLLTR
ECCCCCCCEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA