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The map label for this gene is murI

Identifier: 21673123

GI number: 21673123

Start: 295732

End: 296550

Strand: Reverse

Name: murI

Synonym: CT0284

Alternate gene names: 21673123

Gene position: 296550-295732 (Counterclockwise)

Preceding gene: 21673124

Following gene: 21673122

Centisome position: 13.76

GC content: 59.83

Gene sequence:

>819_bases
ATGCCACAGCACAAGGTTTCATCTGACAGTCCTATCGGCATCTTCGATTCGGGCATCGGTGGTCTGACCGTCGTCAAGGC
CGTGCAGGCCGCACTGCCCTCTGAGCGGATCATCTATTTTGGCGACACGGCTCGCGTACCGTACGGCTCGAAATCGCAGG
TCACGATTCGGAAGTATGCCCGCGAGGACACCGAGCTGTTGATGAAGCACCAGCCGAAGCTCATCATCGTGGCGTGTAAC
ACCGTGTCAGCGCTGGCGCTCGACGTAGTCGAGCAGACTGCCGGAGGCATTCCGGTCATCGGCGTGCTGAAAGCTGGCGC
GGAACTGGCCGTGCAGAAGACGAAATCGGGCCGCATCGGCGTCATCGGCACCCAGGCCACCATCGGCTCGAACGCCTACA
CCTGCGCCATCCGCGAGGAGAAAGAAACACTCGAAGTTTTTCCGAAAGCCTGTCCGCTTTTCGTACCGCTCGCCGAAGAG
GGCTTCATCGATCACCCTGCCACAAGACTTGTCGCCGAAGAATACTTGGCTGCCTTCACCGGTAAAGAGATCGACACCCT
CGTGCTCGGCTGCACCCACTACCCGATTCTCCGCAAGATCATCGAAAGCATCACCGGGCCGGAAATCACCATCATCGACT
CCGCCGAAGCGGTTGCCAGCAAAGCCGGAGAACTCCTCGCAGCTCGCGGCCTCTTGAACCAAAGCCCCGAAAAAGCGCTG
CCGCATCTCATGGTCAGCGACCTCCCGCAGAAGTTCCGCGAACTCTACCGCCTCTTCATGGGCACCGAACTCCCCGACGT
CGAGCTGGTAGGGATGTAG

Upstream 100 bases:

>100_bases
GCAGAAGGTCAAAGAGGCCGGCAAAATGCGCTCCGAAGGCAAAGAGTATGTTGTCAAGGATGGGGATGTGATTACTTTCC
GGTTTAATGTGTAAGACGCC

Downstream 100 bases:

>100_bases
CCATTGCCTTTCCCATTTTAATCGTATCTTTTCCGGCAAAATCTGAACCTTGAAGGCGACGGCCTTACCATACCGGAGAG
ACCAGTGAAAATCAATCTTG

Product: glutamate racemase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 272; Mature: 271

Protein sequence:

>272_residues
MPQHKVSSDSPIGIFDSGIGGLTVVKAVQAALPSERIIYFGDTARVPYGSKSQVTIRKYAREDTELLMKHQPKLIIVACN
TVSALALDVVEQTAGGIPVIGVLKAGAELAVQKTKSGRIGVIGTQATIGSNAYTCAIREEKETLEVFPKACPLFVPLAEE
GFIDHPATRLVAEEYLAAFTGKEIDTLVLGCTHYPILRKIIESITGPEITIIDSAEAVASKAGELLAARGLLNQSPEKAL
PHLMVSDLPQKFRELYRLFMGTELPDVELVGM

Sequences:

>Translated_272_residues
MPQHKVSSDSPIGIFDSGIGGLTVVKAVQAALPSERIIYFGDTARVPYGSKSQVTIRKYAREDTELLMKHQPKLIIVACN
TVSALALDVVEQTAGGIPVIGVLKAGAELAVQKTKSGRIGVIGTQATIGSNAYTCAIREEKETLEVFPKACPLFVPLAEE
GFIDHPATRLVAEEYLAAFTGKEIDTLVLGCTHYPILRKIIESITGPEITIIDSAEAVASKAGELLAARGLLNQSPEKAL
PHLMVSDLPQKFRELYRLFMGTELPDVELVGM
>Mature_271_residues
PQHKVSSDSPIGIFDSGIGGLTVVKAVQAALPSERIIYFGDTARVPYGSKSQVTIRKYAREDTELLMKHQPKLIIVACNT
VSALALDVVEQTAGGIPVIGVLKAGAELAVQKTKSGRIGVIGTQATIGSNAYTCAIREEKETLEVFPKACPLFVPLAEEG
FIDHPATRLVAEEYLAAFTGKEIDTLVLGCTHYPILRKIIESITGPEITIIDSAEAVASKAGELLAARGLLNQSPEKALP
HLMVSDLPQKFRELYRLFMGTELPDVELVGM

Specific function: Provides the (R)-glutamate required for cell wall biosynthesis

COG id: COG0796

COG function: function code M; Glutamate racemase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aspartate/glutamate racemases family

Homologues:

Organism=Escherichia coli, GI87082355, Length=225, Percent_Identity=29.3333333333333, Blast_Score=78, Evalue=5e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MURI_CHLTE (Q8KFN8)

Other databases:

- EMBL:   AE006470
- RefSeq:   NP_661188.1
- ProteinModelPortal:   Q8KFN8
- SMR:   Q8KFN8
- GeneID:   1007856
- GenomeReviews:   AE006470_GR
- KEGG:   cte:CT0284
- NMPDR:   fig|194439.1.peg.282
- TIGR:   CT0284
- HOGENOM:   HBG645102
- OMA:   VACNTAA
- ProtClustDB:   PRK00865
- BioCyc:   CTEP194439:CT_0284-MONOMER
- BRENDA:   5.1.1.3
- HAMAP:   MF_00258
- InterPro:   IPR015942
- InterPro:   IPR001920
- InterPro:   IPR018187
- InterPro:   IPR004391
- Gene3D:   G3DSA:3.40.50.1860
- TIGRFAMs:   TIGR00067

Pfam domain/function: PF01177 Asp_Glu_race; SSF53681 Asp/Glu_race

EC number: =5.1.1.3

Molecular weight: Translated: 29225; Mature: 29094

Theoretical pI: Translated: 5.70; Mature: 5.70

Prosite motif: PS00923 ASP_GLU_RACEMASE_1; PS00924 ASP_GLU_RACEMASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPQHKVSSDSPIGIFDSGIGGLTVVKAVQAALPSERIIYFGDTARVPYGSKSQVTIRKYA
CCCCCCCCCCCCEEEECCCCHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCCHHHHHH
REDTELLMKHQPKLIIVACNTVSALALDVVEQTAGGIPVIGVLKAGAELAVQKTKSGRIG
HHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHCCCCCEEHHHHCCCHHEEEECCCCCEE
VIGTQATIGSNAYTCAIREEKETLEVFPKACPLFVPLAEEGFIDHPATRLVAEEYLAAFT
EEECCEEECCCEEEEEEECCHHHHHHHHCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHC
GKEIDTLVLGCTHYPILRKIIESITGPEITIIDSAEAVASKAGELLAARGLLNQSPEKAL
CCCCCEEEECCCCHHHHHHHHHHCCCCEEEEEECHHHHHHHHHHHHHHHHHHCCCHHHHH
PHLMVSDLPQKFRELYRLFMGTELPDVELVGM
HHHHHHHHHHHHHHHHHHHHCCCCCCEEEECC
>Mature Secondary Structure 
PQHKVSSDSPIGIFDSGIGGLTVVKAVQAALPSERIIYFGDTARVPYGSKSQVTIRKYA
CCCCCCCCCCCEEEECCCCHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCCHHHHHH
REDTELLMKHQPKLIIVACNTVSALALDVVEQTAGGIPVIGVLKAGAELAVQKTKSGRIG
HHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHCCCCCEEHHHHCCCHHEEEECCCCCEE
VIGTQATIGSNAYTCAIREEKETLEVFPKACPLFVPLAEEGFIDHPATRLVAEEYLAAFT
EEECCEEECCCEEEEEEECCHHHHHHHHCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHC
GKEIDTLVLGCTHYPILRKIIESITGPEITIIDSAEAVASKAGELLAARGLLNQSPEKAL
CCCCCEEEECCCCHHHHHHHHHHCCCCEEEEEECHHHHHHHHHHHHHHHHHHCCCHHHHH
PHLMVSDLPQKFRELYRLFMGTELPDVELVGM
HHHHHHHHHHHHHHHHHHHHCCCCCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12093901