Click here to switch to the map view.

The map label for this gene is engD [H]

Identifier: 21673124

GI number: 21673124

Start: 296557

End: 297648

Strand: Reverse

Name: engD [H]

Synonym: CT0285

Alternate gene names: 21673124

Gene position: 297648-296557 (Counterclockwise)

Preceding gene: 21673128

Following gene: 21673123

Centisome position: 13.81

GC content: 59.34

Gene sequence:

>1092_bases
ATGTCACTTCGCTGCGGCATTGTCGGTCTGCCCAATGTCGGCAAATCGACGCTGTTCAATGCTATCACGGCCAAGCAGGC
CGAAGCCGCCAACTACCCGTTCTGCACCATCGAACCCAACGTCGGCACCGTGCTCGTGCCCGATCCGCGCCTCAGTGAAC
TCGCCCGCGTCGTCAAGACTCCGGTGATCGTGCCTGCGGTGCTCGAAATCGTCGATATTGCCGGTCTGGTCAGAGGTGCC
AGCAAGGGTGAAGGACTTGGCAACCAGTTCCTCTCGCACATCCGCGAGGTTGACGCGATCATTCACGTGGTACGCTGCTT
CGAGGATCCGAACATCATCCACGTCGAAGGCAAAATCGATCCGGCGGGCGACATCGCCACCATCGAGACCGAGCTGATGC
TGGCCGACCTCGACAGCATGGAAAAGCGCATCGACAAATTGCGCAAGGGTGCCCGCAAGGAGAAAGATCAGCAGGCGCTG
GTCGATCTGGCCGAGAAGATCGTGGCCGGACTCGGCGAGGGCGTGCCGGTGCGCAGCATTCTCGAAAACGACGAAGAACG
CGCCATGGCGAAACAGTTTTTCCTCATCACGGCAAAGCCGGTGCTTTTTGCCGCCAATGTGGCTGAAACCGACCTGCCTG
ATGGTAACGAGCATACCGCAACGGTGGCGAAGATAGCAGCAGAGAACGGTTCGAAAATGCTCATCATCAGCGCCAAAGCC
GAAGCGGACATTGCCGAGCTGCCCGAAGAGGAGCGTCCGGACTTCCTCGAAAGCCTCGGCCTCGAAATGTCGGGCCTCGA
CCGCCTGATCATGGCCGCCTACAACCTGCTCGGCCTGCACAACTACTTCACGGCAGGCGTCAAGGAGGTTCACGCCTGGA
CGATCCGCAAGGGCGCCGCCGCTCCGGAAGCCGCCGCCGCGATCCACTCCGACTTCGAGAAGGGCTTCATCAGGGCCGAG
GTGATGGCCTACGAAGACCTGATAACTCTCGGCTCGGAGCAGAAGGTCAAAGAGGCCGGCAAAATGCGCTCCGAAGGCAA
AGAGTATGTTGTCAAGGATGGGGATGTGATTACTTTCCGGTTTAATGTGTAA

Upstream 100 bases:

>100_bases
TGCATTTTAAAATAGCCTGTAATTGTAAAAAATTAATTTGCTTTTTCCAAACGAATTGATTACATGTTAAAACCGTTTTT
CTCAACAAACATCTCCGCCC

Downstream 100 bases:

>100_bases
GACGCCATGCCACAGCACAAGGTTTCATCTGACAGTCCTATCGGCATCTTCGATTCGGGCATCGGTGGTCTGACCGTCGT
CAAGGCCGTGCAGGCCGCAC

Product: GTP-dependent nucleic acid-binding protein EngD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 363; Mature: 362

Protein sequence:

>363_residues
MSLRCGIVGLPNVGKSTLFNAITAKQAEAANYPFCTIEPNVGTVLVPDPRLSELARVVKTPVIVPAVLEIVDIAGLVRGA
SKGEGLGNQFLSHIREVDAIIHVVRCFEDPNIIHVEGKIDPAGDIATIETELMLADLDSMEKRIDKLRKGARKEKDQQAL
VDLAEKIVAGLGEGVPVRSILENDEERAMAKQFFLITAKPVLFAANVAETDLPDGNEHTATVAKIAAENGSKMLIISAKA
EADIAELPEEERPDFLESLGLEMSGLDRLIMAAYNLLGLHNYFTAGVKEVHAWTIRKGAAAPEAAAAIHSDFEKGFIRAE
VMAYEDLITLGSEQKVKEAGKMRSEGKEYVVKDGDVITFRFNV

Sequences:

>Translated_363_residues
MSLRCGIVGLPNVGKSTLFNAITAKQAEAANYPFCTIEPNVGTVLVPDPRLSELARVVKTPVIVPAVLEIVDIAGLVRGA
SKGEGLGNQFLSHIREVDAIIHVVRCFEDPNIIHVEGKIDPAGDIATIETELMLADLDSMEKRIDKLRKGARKEKDQQAL
VDLAEKIVAGLGEGVPVRSILENDEERAMAKQFFLITAKPVLFAANVAETDLPDGNEHTATVAKIAAENGSKMLIISAKA
EADIAELPEEERPDFLESLGLEMSGLDRLIMAAYNLLGLHNYFTAGVKEVHAWTIRKGAAAPEAAAAIHSDFEKGFIRAE
VMAYEDLITLGSEQKVKEAGKMRSEGKEYVVKDGDVITFRFNV
>Mature_362_residues
SLRCGIVGLPNVGKSTLFNAITAKQAEAANYPFCTIEPNVGTVLVPDPRLSELARVVKTPVIVPAVLEIVDIAGLVRGAS
KGEGLGNQFLSHIREVDAIIHVVRCFEDPNIIHVEGKIDPAGDIATIETELMLADLDSMEKRIDKLRKGARKEKDQQALV
DLAEKIVAGLGEGVPVRSILENDEERAMAKQFFLITAKPVLFAANVAETDLPDGNEHTATVAKIAAENGSKMLIISAKAE
ADIAELPEEERPDFLESLGLEMSGLDRLIMAAYNLLGLHNYFTAGVKEVHAWTIRKGAAAPEAAAAIHSDFEKGFIRAEV
MAYEDLITLGSEQKVKEAGKMRSEGKEYVVKDGDVITFRFNV

Specific function: GTP-dependent nucleic acid-binding protein which may act as a translation factor [H]

COG id: COG0012

COG function: function code J; Predicted GTPase, probable translation factor

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 G (guanine nucleotide-binding) domain [H]

Homologues:

Organism=Homo sapiens, GI58761500, Length=369, Percent_Identity=45.7994579945799, Blast_Score=303, Evalue=1e-82,
Organism=Homo sapiens, GI58761502, Length=227, Percent_Identity=40.0881057268723, Blast_Score=148, Evalue=7e-36,
Organism=Escherichia coli, GI1787454, Length=364, Percent_Identity=56.8681318681319, Blast_Score=408, Evalue=1e-115,
Organism=Escherichia coli, GI1789574, Length=99, Percent_Identity=32.3232323232323, Blast_Score=69, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI17509631, Length=368, Percent_Identity=43.2065217391304, Blast_Score=304, Evalue=4e-83,
Organism=Saccharomyces cerevisiae, GI6319499, Length=370, Percent_Identity=41.6216216216216, Blast_Score=262, Evalue=8e-71,
Organism=Saccharomyces cerevisiae, GI6321773, Length=379, Percent_Identity=36.4116094986807, Blast_Score=227, Evalue=3e-60,
Organism=Saccharomyces cerevisiae, GI6321649, Length=324, Percent_Identity=26.8518518518519, Blast_Score=88, Evalue=2e-18,
Organism=Saccharomyces cerevisiae, GI6321962, Length=129, Percent_Identity=27.1317829457364, Blast_Score=63, Evalue=6e-11,
Organism=Drosophila melanogaster, GI24640873, Length=369, Percent_Identity=43.9024390243902, Blast_Score=287, Evalue=7e-78,
Organism=Drosophila melanogaster, GI24640877, Length=369, Percent_Identity=43.9024390243902, Blast_Score=287, Evalue=7e-78,
Organism=Drosophila melanogaster, GI24640875, Length=369, Percent_Identity=43.9024390243902, Blast_Score=287, Evalue=7e-78,
Organism=Drosophila melanogaster, GI24640879, Length=327, Percent_Identity=41.5902140672783, Blast_Score=230, Evalue=1e-60,
Organism=Drosophila melanogaster, GI24585318, Length=140, Percent_Identity=31.4285714285714, Blast_Score=70, Evalue=2e-12,

Paralogues:

None

Copy number: 120 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 140 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012675
- InterPro:   IPR004396
- InterPro:   IPR013029
- InterPro:   IPR006073
- InterPro:   IPR002917
- InterPro:   IPR012676
- InterPro:   IPR023192 [H]

Pfam domain/function: PF01926 MMR_HSR1; PF06071 YchF-GTPase_C [H]

EC number: NA

Molecular weight: Translated: 39340; Mature: 39209

Theoretical pI: Translated: 4.76; Mature: 4.76

Prosite motif: PS00443 GATASE_TYPE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLRCGIVGLPNVGKSTLFNAITAKQAEAANYPFCTIEPNVGTVLVPDPRLSELARVVKT
CCCEECEEECCCCCHHHHHHHHHHHHHHCCCCCEEEECCCCCEEEECCCCHHHHHHHHHC
PVIVPAVLEIVDIAGLVRGASKGEGLGNQFLSHIREVDAIIHVVRCFEDPNIIHVEGKID
CCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCC
PAGDIATIETELMLADLDSMEKRIDKLRKGARKEKDQQALVDLAEKIVAGLGEGVPVRSI
CCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCHHHH
LENDEERAMAKQFFLITAKPVLFAANVAETDLPDGNEHTATVAKIAAENGSKMLIISAKA
HCCCHHHHHHHHHHEEEECHHHEECCCCCCCCCCCCCHHHHHHHHHHCCCCEEEEEECCC
EADIAELPEEERPDFLESLGLEMSGLDRLIMAAYNLLGLHNYFTAGVKEVHAWTIRKGAA
CCCHHHCCCCCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
APEAAAAIHSDFEKGFIRAEVMAYEDLITLGSEQKVKEAGKMRSEGKEYVVKDGDVITFR
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCEEEEECCCEEEEE
FNV
ECC
>Mature Secondary Structure 
SLRCGIVGLPNVGKSTLFNAITAKQAEAANYPFCTIEPNVGTVLVPDPRLSELARVVKT
CCEECEEECCCCCHHHHHHHHHHHHHHCCCCCEEEECCCCCEEEECCCCHHHHHHHHHC
PVIVPAVLEIVDIAGLVRGASKGEGLGNQFLSHIREVDAIIHVVRCFEDPNIIHVEGKID
CCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCC
PAGDIATIETELMLADLDSMEKRIDKLRKGARKEKDQQALVDLAEKIVAGLGEGVPVRSI
CCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCHHHH
LENDEERAMAKQFFLITAKPVLFAANVAETDLPDGNEHTATVAKIAAENGSKMLIISAKA
HCCCHHHHHHHHHHEEEECHHHEECCCCCCCCCCCCCHHHHHHHHHHCCCCEEEEEECCC
EADIAELPEEERPDFLESLGLEMSGLDRLIMAAYNLLGLHNYFTAGVKEVHAWTIRKGAA
CCCHHHCCCCCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
APEAAAAIHSDFEKGFIRAEVMAYEDLITLGSEQKVKEAGKMRSEGKEYVVKDGDVITFR
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCEEEEECCCEEEEE
FNV
ECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377 [H]