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The map label for this gene is yjl094C [H]

Identifier: 21243532

GI number: 21243532

Start: 3288652

End: 3289917

Strand: Reverse

Name: yjl094C [H]

Synonym: XAC2805

Alternate gene names: 21243532

Gene position: 3289917-3288652 (Counterclockwise)

Preceding gene: 21243533

Following gene: 21243529

Centisome position: 63.57

GC content: 64.14

Gene sequence:

>1266_bases
ATGACCACTCCGCAGATGTCGGTGTACTTCTTTTTGCAGGCGGCCGCGATTTTGTTGGTATGCCGGCTGGTCGGCATGCT
GGCCAAGCGCCTCGGGCAACCGCAGGTGGTGGGGGAAATGATTGCCGGCGTGATGCTGGGGCCCTCGTTGTTCGGCTTGC
TGGCGCCAGGCGTGCAGGCGGCCCTGTTCCCCAAGCAGACCATGGACGTGCTGTATGTGTTCGCGCAGTTCGGCGTGGGC
CTGTACATGTTCCTGGTCGGAACCGATTTCCGCGGCGACCACTTTCGCGCGCGCTATCGCAGCGCCATGAGCGTGTCGAT
GGCGGGCATCGCGGTGCCGTTCCTGCTGGCGTTCGCCATGTGCCCGTGGCTGATCAACGTGGATGGCCTGTTTTCGGAAA
AGGCCAAGCTGACCGAAGCGTCGTTGTTCCTGGGCGCGGCGATCGCGATCACCGCCTTTCCGATGCTGGCGCGCATCATC
CACGAACGCGGTCTGACCAATAGCCCGTTGGGCACCTTGGCGCTGACCGCTGGCGCGTTCGACGATGCCGCAGCGTGGTG
CATTCTGGCCGTGGTGCTGGCCAGTTTCGGCGGCAGTTGGGGCAGTGCCTACCTGGCCATCGGCGGCGGCATCGGCTATG
CGGTCTTCATGATTTTCGTCGGCCGGCATCTGCTCAAGCGGCTGGCCGATCATGTGGTGCCCGGCCAGCCGCTGAGCAAC
AGTGTCCTGGCGGTCGTGCTGATCCTGTTCTGCACCAGCGCCTGGGCGATGGATGCGATCGGCATCCATGCAGTGTTCGG
CGGTTTCCTGCTCGGTGTCTGCCTGCCCAGGGGCGCACTGACCGAGAAGCTGCGCGAGATGCTGCAGCCGTTCGTCGTGG
TGCTGTTGCTGCCGATGTTCTTCACCTATTCGGGCTTGAAAACCCAGCTCAGCGTGTTGCTGCAGCCGCAGATCATGCTG
GCCGGCGTGGCGATCCTGGCCGCATCGTTCATCGGCAAGGGTGTGGCCTGCTGGGCCGCGGCGCGTGCCACCGGCGAGAA
CAACCGCGACGCCATGGCGATCGGTTCGCTGATGAATGCACGCGGGTTGATGGAGCTGATCATCATCAACATCGGCTTGC
AGGCGGGTGTAATCGAGCAGGGCCTGTTCTCGGTGCTGGTGCTGATGGCGATCCTGTCCACGCTGATGGCCACGCCGTTG
TTCAACTGGATCATGCGCCGCCACGCCCATGTGAGCGACGCGGTGCCGAGCCTGCAGTCGCGGTGA

Upstream 100 bases:

>100_bases
AGCGCGCAGGTGGGCTTGGATCGCCACGGCAGCCGCACGCTATCGAAGTGCGGCAGCTCCGGTTACGATCTGCGCACTTT
TCACGGATGTTGCCGCACGC

Downstream 100 bases:

>100_bases
TCGGTTGCGCAACTGCCCGCAGGTGCGGGCAGTTGCGTCGGCGTGCGCGTGGCCGGGCGTTGCGTCAACGCCCCAGCGGT
AACTGCACGCTGGCCAGCAG

Product: cation:proton antiporter

Products: Proton [Cytoplasm]; K (I) [Periplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 421; Mature: 420

Protein sequence:

>421_residues
MTTPQMSVYFFLQAAAILLVCRLVGMLAKRLGQPQVVGEMIAGVMLGPSLFGLLAPGVQAALFPKQTMDVLYVFAQFGVG
LYMFLVGTDFRGDHFRARYRSAMSVSMAGIAVPFLLAFAMCPWLINVDGLFSEKAKLTEASLFLGAAIAITAFPMLARII
HERGLTNSPLGTLALTAGAFDDAAAWCILAVVLASFGGSWGSAYLAIGGGIGYAVFMIFVGRHLLKRLADHVVPGQPLSN
SVLAVVLILFCTSAWAMDAIGIHAVFGGFLLGVCLPRGALTEKLREMLQPFVVVLLLPMFFTYSGLKTQLSVLLQPQIML
AGVAILAASFIGKGVACWAAARATGENNRDAMAIGSLMNARGLMELIIINIGLQAGVIEQGLFSVLVLMAILSTLMATPL
FNWIMRRHAHVSDAVPSLQSR

Sequences:

>Translated_421_residues
MTTPQMSVYFFLQAAAILLVCRLVGMLAKRLGQPQVVGEMIAGVMLGPSLFGLLAPGVQAALFPKQTMDVLYVFAQFGVG
LYMFLVGTDFRGDHFRARYRSAMSVSMAGIAVPFLLAFAMCPWLINVDGLFSEKAKLTEASLFLGAAIAITAFPMLARII
HERGLTNSPLGTLALTAGAFDDAAAWCILAVVLASFGGSWGSAYLAIGGGIGYAVFMIFVGRHLLKRLADHVVPGQPLSN
SVLAVVLILFCTSAWAMDAIGIHAVFGGFLLGVCLPRGALTEKLREMLQPFVVVLLLPMFFTYSGLKTQLSVLLQPQIML
AGVAILAASFIGKGVACWAAARATGENNRDAMAIGSLMNARGLMELIIINIGLQAGVIEQGLFSVLVLMAILSTLMATPL
FNWIMRRHAHVSDAVPSLQSR
>Mature_420_residues
TTPQMSVYFFLQAAAILLVCRLVGMLAKRLGQPQVVGEMIAGVMLGPSLFGLLAPGVQAALFPKQTMDVLYVFAQFGVGL
YMFLVGTDFRGDHFRARYRSAMSVSMAGIAVPFLLAFAMCPWLINVDGLFSEKAKLTEASLFLGAAIAITAFPMLARIIH
ERGLTNSPLGTLALTAGAFDDAAAWCILAVVLASFGGSWGSAYLAIGGGIGYAVFMIFVGRHLLKRLADHVVPGQPLSNS
VLAVVLILFCTSAWAMDAIGIHAVFGGFLLGVCLPRGALTEKLREMLQPFVVVLLLPMFFTYSGLKTQLSVLLQPQIMLA
GVAILAASFIGKGVACWAAARATGENNRDAMAIGSLMNARGLMELIIINIGLQAGVIEQGLFSVLVLMAILSTLMATPLF
NWIMRRHAHVSDAVPSLQSR

Specific function: This is a Na(+)/H(+) antiporter. It can mediate sodium uptake when a transmembrane pH gradient is applied [H]

COG id: COG0475

COG function: function code P; Kef-type K+ transport systems, membrane components

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family [H]

Homologues:

Organism=Escherichia coli, GI1789749, Length=387, Percent_Identity=24.2894056847545, Blast_Score=62, Evalue=7e-11,
Organism=Saccharomyces cerevisiae, GI6322367, Length=405, Percent_Identity=30.8641975308642, Blast_Score=181, Evalue=2e-46,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006153
- InterPro:   IPR004771 [H]

Pfam domain/function: PF00999 Na_H_Exchanger [H]

EC number: NA

Molecular weight: Translated: 44890; Mature: 44759

Theoretical pI: Translated: 9.25; Mature: 9.25

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
5.2 %Met     (Translated Protein)
6.7 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
5.0 %Met     (Mature Protein)
6.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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C
>Mature Secondary Structure 
TTPQMSVYFFLQAAAILLVCRLVGMLAKRLGQPQVVGEMIAGVMLGPSLFGLLAPGVQA
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCHHH
ALFPKQTMDVLYVFAQFGVGLYMFLVGTDFRGDHFRARYRSAMSVSMAGIAVPFLLAFAM
HHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
CPWLINVDGLFSEKAKLTEASLFLGAAIAITAFPMLARIIHERGLTNSPLGTLALTAGAF
HHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHEECCCC
DDAAAWCILAVVLASFGGSWGSAYLAIGGGIGYAVFMIFVGRHLLKRLADHVVPGQPLSN
HHHHHHHHHHHHHHHHCCCCCCCCEEECCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCH
SVLAVVLILFCTSAWAMDAIGIHAVFGGFLLGVCLPRGALTEKLREMLQPFVVVLLLPMF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHH
FTYSGLKTQLSVLLQPQIMLAGVAILAASFIGKGVACWAAARATGENNRDAMAIGSLMNA
HHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCHHHHHHHHHHH
RGLMELIIINIGLQAGVIEQGLFSVLVLMAILSTLMATPLFNWIMRRHAHVSDAVPSLQS
HHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
R
C

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; K (I) [Cytoplasm] [C]

Specific reaction: Proton [Periplasm] + K (I) [Cytoplasm] = Proton [Cytoplasm] + K (I) [Periplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1312090; 1325937 [H]