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The map label for this gene is coaE [H]

Identifier: 209696041

GI number: 209696041

Start: 2849518

End: 2850141

Strand: Direct

Name: coaE [H]

Synonym: VSAL_I2633

Alternate gene names: 209696041

Gene position: 2849518-2850141 (Clockwise)

Preceding gene: 209696040

Following gene: 209696042

Centisome position: 85.7

GC content: 36.06

Gene sequence:

>624_bases
ATGAGTTATGTCATCGCTATTACGGGTGGTATAGGCAGTGGTAAAACGACAATTGCAGATAAATTTAACCAATTATATGA
CATTGATATTGTTGATGCCGATATCATTGCTCGTGACGTTGTTAAACCGAAAACAAACGGATTACACCAAATCGAAGCGC
ATTTTGGATCCTCGATTTTATTAAGTGATGGCAGTTTAAATCGTGCAGAGTTACGACAACGTATTTTTTCTGCTCCAAAA
GAAAAAGAATGGCTAAATAATTTACTTCATCCTTTAATTCGCCAAGAGATGCAACATCAGATTACTCTGACTCAAGCGCC
ATACGCTTTACTCGTTGTCCCTCTATTAGTTGAAAACAATCTACAAAACTTAGCAAATCGTATTCTCATTGTTGATGTTT
CGGAGCAAACTCAAATTAATCGAACAATGAATCGTGATAGAGTAACTAATGAACAAGTTAATGCTATTCTTGCTTCTCAA
GCAAGTCGAGAGCAACGTCTAGCGATTGCCGATGATGTCATTGATAATAACCAACAAAATGTAGACCTTAATAGCAAAAT
TGCTCTTCTACATCAGAAATATCTGGTATTGTCTCAAGCCTCTAAGATAGAAGAAAAGAATTGA

Upstream 100 bases:

>100_bases
TTCCATTTGGTCCTTATCTCGCGATTGCAGGTTGGATATGTTTATTGTGGGGCCAAGAAATTAGCCAATGGTACTTCACC
TCAATTCTAGGGTTTCCCGT

Downstream 100 bases:

>100_bases
TAACGACTATGAATGGACTTGGAATGCAAAAGTTTGAACATCCTTTAAATGAAAGGACTCGAATTTATTTACGTATAGAA
TCTCTATTGCGTAAGCTTGG

Product: dephospho-CoA kinase (dephosphocoenzyme a kinase)

Products: NA

Alternate protein names: Dephosphocoenzyme A kinase [H]

Number of amino acids: Translated: 207; Mature: 206

Protein sequence:

>207_residues
MSYVIAITGGIGSGKTTIADKFNQLYDIDIVDADIIARDVVKPKTNGLHQIEAHFGSSILLSDGSLNRAELRQRIFSAPK
EKEWLNNLLHPLIRQEMQHQITLTQAPYALLVVPLLVENNLQNLANRILIVDVSEQTQINRTMNRDRVTNEQVNAILASQ
ASREQRLAIADDVIDNNQQNVDLNSKIALLHQKYLVLSQASKIEEKN

Sequences:

>Translated_207_residues
MSYVIAITGGIGSGKTTIADKFNQLYDIDIVDADIIARDVVKPKTNGLHQIEAHFGSSILLSDGSLNRAELRQRIFSAPK
EKEWLNNLLHPLIRQEMQHQITLTQAPYALLVVPLLVENNLQNLANRILIVDVSEQTQINRTMNRDRVTNEQVNAILASQ
ASREQRLAIADDVIDNNQQNVDLNSKIALLHQKYLVLSQASKIEEKN
>Mature_206_residues
SYVIAITGGIGSGKTTIADKFNQLYDIDIVDADIIARDVVKPKTNGLHQIEAHFGSSILLSDGSLNRAELRQRIFSAPKE
KEWLNNLLHPLIRQEMQHQITLTQAPYALLVVPLLVENNLQNLANRILIVDVSEQTQINRTMNRDRVTNEQVNAILASQA
SREQRLAIADDVIDNNQQNVDLNSKIALLHQKYLVLSQASKIEEKN

Specific function: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A [H]

COG id: COG0237

COG function: function code H; Dephospho-CoA kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 DPCK (dephospho-CoA kinase) domain [H]

Homologues:

Organism=Homo sapiens, GI191252797, Length=193, Percent_Identity=31.0880829015544, Blast_Score=100, Evalue=1e-21,
Organism=Homo sapiens, GI191252795, Length=193, Percent_Identity=31.0880829015544, Blast_Score=100, Evalue=1e-21,
Organism=Homo sapiens, GI110227607, Length=167, Percent_Identity=28.1437125748503, Blast_Score=73, Evalue=2e-13,
Organism=Homo sapiens, GI110227605, Length=167, Percent_Identity=28.1437125748503, Blast_Score=72, Evalue=4e-13,
Organism=Homo sapiens, GI110227603, Length=167, Percent_Identity=28.1437125748503, Blast_Score=72, Evalue=4e-13,
Organism=Homo sapiens, GI110227601, Length=167, Percent_Identity=28.1437125748503, Blast_Score=72, Evalue=4e-13,
Organism=Homo sapiens, GI205277394, Length=167, Percent_Identity=28.1437125748503, Blast_Score=72, Evalue=5e-13,
Organism=Escherichia coli, GI1786292, Length=206, Percent_Identity=56.7961165048544, Blast_Score=222, Evalue=1e-59,
Organism=Caenorhabditis elegans, GI17554944, Length=189, Percent_Identity=29.6296296296296, Blast_Score=96, Evalue=1e-20,
Organism=Saccharomyces cerevisiae, GI6320402, Length=191, Percent_Identity=37.696335078534, Blast_Score=117, Evalue=2e-27,
Organism=Drosophila melanogaster, GI24644728, Length=179, Percent_Identity=31.2849162011173, Blast_Score=96, Evalue=2e-20,
Organism=Drosophila melanogaster, GI24658602, Length=191, Percent_Identity=25.6544502617801, Blast_Score=71, Evalue=6e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001977 [H]

Pfam domain/function: PF01121 CoaE [H]

EC number: =2.7.1.24 [H]

Molecular weight: Translated: 23255; Mature: 23124

Theoretical pI: Translated: 6.36; Mature: 6.36

Prosite motif: PS01294 COAE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSYVIAITGGIGSGKTTIADKFNQLYDIDIVDADIIARDVVKPKTNGLHQIEAHFGSSIL
CCEEEEEECCCCCCCHHHHHHHHHEEEEEEECHHHHHHHHCCCCCCCHHHHHHHCCCEEE
LSDGSLNRAELRQRIFSAPKEKEWLNNLLHPLIRQEMQHQITLTQAPYALLVVPLLVENN
EECCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHEEEECCCCHHHHHHHHHHHCC
LQNLANRILIVDVSEQTQINRTMNRDRVTNEQVNAILASQASREQRLAIADDVIDNNQQN
HHHHHCEEEEEECCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
VDLNSKIALLHQKYLVLSQASKIEEKN
CCCCHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
SYVIAITGGIGSGKTTIADKFNQLYDIDIVDADIIARDVVKPKTNGLHQIEAHFGSSIL
CEEEEEECCCCCCCHHHHHHHHHEEEEEEECHHHHHHHHCCCCCCCHHHHHHHCCCEEE
LSDGSLNRAELRQRIFSAPKEKEWLNNLLHPLIRQEMQHQITLTQAPYALLVVPLLVENN
EECCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHEEEECCCCHHHHHHHHHHHCC
LQNLANRILIVDVSEQTQINRTMNRDRVTNEQVNAILASQASREQRLAIADDVIDNNQQN
HHHHHCEEEEEECCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
VDLNSKIALLHQKYLVLSQASKIEEKN
CCCCHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10024587; 10952301 [H]